[To describe arthrosis as a "degenerative joint disease" is obsolete].
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A great variety of diseases may express themselves in the form of joint involvement in patients under the age of one year. Articular infections are the most important disease to be recognized due to the urgent need for treatment. Inflammatory diseases and heritable disorders of various origins may also start early in life.
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Drug discovery and delivery to retard the degeneration of joint tissues are challenging. Current treatment is generally inadequate. This commentary places in perspective the inadequacy characteristic of existing therapeutics and the promising developments embodied in the newer therapeutics administered via the oral or intra-auricular routes.
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