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An evaluation of growth changes and treatment effects in Class II, Division 1 malocclusion with conventional roentgenographic cephalometry and finite element method analysis.

Conventional methods of roentgenographic cephalometry will yield differences in interpretation of growth or treatment changes depending on which methods of superimposition are used. The finite element method of analysis has been reported to have significant advantages since it does not require a reference frame to describe the changes that have taken place. This article describes the growth of a patient with a Class II, Division 1 malocclusion during approximately 2 years of orthodontic treatment with the use of conventional cephalometric growth and static analyses, as well as the finite element method. Thirty cephalometric points were digitized on the pretreatment and the posttreatment lateral cephalograms of a patient undergoing orthodontic treatment between the ages of 10 and 12 years. The finite element method provided a reference frame invariant description of the size, shape, change, and rotation of each of the 12 finite elements representing different anatomic structures.

Cephalometry↗

Growth allometry of the mandibles of giant transgenic mice: an analysis based on the finite-element scaling method.

Transgenic mice genetically engineered to produce increased levels of growth hormones, accelerated somatic growth, and larger terminal sizes [Palmiter et al., 1982, 1983] offer an intriguing model with which to investigate the genetic and developmental control of skeletal proportions. In this study, form differences in the mandible between giant transgenic mice (MT-rGH) and their normal litter-mate controls are examined using data generated by finite-element scaling analysis (FESA). Finite-element scaling analysis is a tensor based method developed to study morphological differences between forms. The method uses landmark data to provide measures of size and shape differences local to those landmarks of mandibular size and shape differences for 18 landmarks were compared between the two mouse samples. Bivariate and multivariate analyses were completed to ascertain 1) whether the mandible of larger transgenic mice differed significantly from normal controls, and 2) if observed proportion change resulted from the general allometric affects of overall mandibular size increase. Comparisons of local size and shape differences against a measure of total size difference reveal similar trajectories of growth allometry, indicating that proportion differences between adult control and transgenic mice result from ontogenic scaling.

Animals↗

Migration, stem shape, and surface finish in cemented total hip arthroplasty.

In many recent publications it was suggested that the amount of early subsidence of a femoral stem in total hip arthroplasty is indicative for later revision. In this article it is argued that stems can be designed according to alternative objectives, resulting in different shapes and surface roughness, each producing its own characteristic postoperative subsidence pattern. It was investigated whether these inherent subsidence patterns can be estimated in preclinical testing. For that purpose two stems, both without a collar, relying on cement fixation only, were compared regarding their stress transfer, migration, and induced micromotion behavior. Finite element analysis, cyclic bench testing of substitute bone reconstructions, and clinical radiostereophotogrammetric analysis were applied. The stems investigated were the Exeter, which is assumed to be a force closed fixation design, relying on subsidence under load as a method of maintaining stability, and the SHP, as a shape closed fixation design, meant to be contained by the cement mantle. Both designs were true to their design concepts in the analyses, in the sense that migrations and micromotions of the Exeter stems far exceeded those of the SHP stems. It was found that preclinical studies such as finite element analysis or bench tests give reasonable indications of in vivo postoperative behavior. It is concluded that early clinical migration values should be considered relative to stem shape and surface finish, when prediction of later revision probability is the issue.

Aged↗

Two-dimensional finite element method analysis of the proximal end of the femur.

The effects of differences in the models in the two dimensional analysis of the proximal end of the femur were investigated. The models were compared by the following four types of analysis: (1) the model having the same mechanical property entirely, (2) the model in which the mechanical property of the cortical bone of the diaphysis differs from that of the cancellous bone in the femoral head, (3) the model being the same as (2), except that the thin cortical bone is set around the bones other than cortical bone of the diaphysis, and (4) the model having several mechanical properties in the cancellous bones. As a result, it is evident that model formation is very important in the analysis of the locomotive organs in vivo by the finite element method. The analysis was performed by using the NASTRAN program. THe report of R. Scholten was used as a reference for the element divisions and the mechanical properties.

Femur Head↗

Three-dimensional finite element stress analysis of a cuneiform-geometry implant.

PURPOSE: The biomechanical behavior of an osseointegrated dental implant plays an important role in its functional longevity inside the bone. Studies of this aspect of dental implants by the finite element method are ongoing. In the present study, a cuneiform-geometry implant was considered with a 3-dimensional model that had a mesh that was finer than in the models commonly found in the literature. MATERIALS AND METHODS: A mechanical model of an edentulous mandible was generated from computerized tomography, with the implant placed in the left first premolar region. A 100-N axial load was applied at the implant abutment, and the mandibular boundary conditions were modeled considering the real geometry of its muscle supporting system. The cortical and trabecular bone was assumed to be homogeneous, isotropic, and linearly elastic. RESULTS: The stress analysis provided results that were used to plot global and detailed graphics of normal maximum (S1), minimum (S3), and von Mises stress fields. The results obtained were analyzed and compared qualitatively with the literature. DISCUSSION: Quantitative comparisons were not performed because of basic differences between the model adopted here and those used by other authors. The stress distribution pattern for the studied geometry was similar to those found in the current literature, but insignificant apical stress concentration occurred. The stress concentration occurred at the neck of the implant, ie, in the cortical bone, which was similar to results for other implant shapes reported in the literature. CONCLUSION: The studied geometry showed a smooth stress pattern, with stress concentrated in the cervical region. The values, however, were within the range of values found in the cortical layer far from the implant, caused by the muscular action. No significant stress concentration was found in the apical area.

Computer Simulation↗

Finite element stress analysis of left ventricular mechanics in the beating dog heart.

A three-dimensional finite element model was used to explore whether or not transmural distributions of end-diastolic and end-systolic fiber stress are uniform from the apex to the base of the canine left ventricular wall. An elastance model for active fiber stress was incorporated in an axisymmetric model that accurately represented the geometry and fiber angle distribution of the anterior free wall. The nonlinear constitutive equation for the resting myocardium was transversely isotropic with respect to the local fiber axis. Transmural distributions of end-diastolic fiber stress became increasingly nonuniform from midventricle toward the apex or the base. At a typical diastolic left ventricular pressure (1 kPa), the differences between largest and smallest fiber stresses were only 0.5 kPa near midventricle, compared with 4.6 kPa at the apex, and 3.3 kPa at the base. Transmural fiber stress differences at end-systole (14 kPa) were relatively small in regions from the base to the midventricle (13-22 kPa), but were larger between midventricle and the apex (30-43 kPa). All six three-dimensional end-diastolic strain components were within or very close to one standard deviation of published measurements through the midanterior left ventricular free wall of the passive canine heart [Omens et al., Am. J. Physiol. 261, H918-H928 (1991)]. End-systolic in-plane normal and shear strains also agreed closely with published experimental measurements in the beating dog heart [Waldman et al., Circ. Res. 63, 550-562 (1988)]. The results indicate that, unlike in the midventricle region that has been studied most fully, there may be significant regional nonhomogeneity of fiber stress in the normal left ventricle associated with regional variations in shape and fiber angle.

Animals↗

Finite element stress analysis of simulated metastatic lesions in the lumbar vertebral body.

A three-dimensional finite element model of a lumbar vertebral body was developed to study the effects of geometry, material properties and loading conditions on stresses in the presence of metastatic lesions. Parameters studied included location and size of the lesion, modulus of the cortical and trabecular bone within and near the lesion, generalized osteoporosis and load distribution. The results, expressed as ratios of peak values of displacement and stress, relative to a normal baseline case, indicated that the location of a defect which did not penetrate the cortex had a minor influence on the peak displacement and stresses, as did the presence of lesions occupying less than 40% of the volume of the vertebral centrum. A lesion occupying 40% of the centrum volume increased the endplate displacement by 2.9 times, the peak tensile stress in the cortical shell by 2.2 times, and the peak von Mises stress in the endplate by 2.8 times. When this lesion penetrated the cortex, these values increased to 3.8, 3.3 and 4.4 times, respectively. The most severe case involved a defect penetrating the anterior cortex, osteoporotic bone properties and anteriorly eccentric loading. In this case, the peak values increased to 8.4, 3.4 and 5.9 times their baseline values, respectively. The results are consistent with a model of the vertebral body as a stiff frame of cortical bone surrounding a relatively compliant core of trabecular bone. Only variations in geometry and properties large enough to lessen significantly the structural stiffness affect the peak stresses and displacements.(ABSTRACT TRUNCATED AT 250 WORDS)

Humans↗

Removal of the subchondral plate in acetabular preparation.

Retention of the subchondral plate during acetabular preparation in total hip replacement is believed to be an important part of modern cementing techniques. We have constructed a two-dimensional finite element analysis to assess the effect of retention and removal of this relatively stiff structure. The finite element analysis demonstrates increased stiffness and stress concentrations at the bone-cement interface that may have an adverse effect. Although further study is required, it may be that subchondral bone retention is not advantageous.

Acetabulum↗

Influence of implant length and bicortical anchorage on implant stress distribution.

BACKGROUND: Short implants present superior failure rates for everybody. PURPOSE: The aim of this theoretic study was to assess to what extent implant length and bicortical anchorage affect the way stress is transferred to implant components, the implant proper, and the surrounding bone. MATERIALS AND METHODS: Stress analysis was performed using finite element analysis. A three-dimensional linear elastic model was generated. All implants modeled were of the same diameter (3.75 mm) but varied in length, at 6, 7, 8, 9, 10, 11, and 12 mm (Brånemark System, Nobel Biocare AB, Gothenburg, Sweden). Each implant was modeled with a titanium abutment screw and abutment, a gold cylinder and prosthetic screw, and a ceramic crown. The implants were seated in a supporting bone structure consisting of cortical and cancellous bone. An occlusal load of 100 N was applied at a 30 degrees angle to the buccolingual plane. RESULTS: With the selected model and bone properties, the coronal cortical anchorage was dominating, and the bone stress concentrated to that area. CONCLUSIONS: The maximum bone stress was virtually constant, independent of implant length and bicortical anchorage. The maximum implant stress, however, increased somewhat with implant length and bicortical anchorage.

Bone and Bones↗

Three-dimensional computerized stress analysis of commercially pure titanium and yttrium-partially stabilized zirconia implants.

PURPOSE: The purpose of this study was to use three-dimensional finite element analysis to analyze stress distribution patterns in Re-Implant implants made of commercially pure titanium (cpTi) and yttrium-partially stabilized zirconia (YPSZ). MATERIALS AND METHODS: Two three-dimensional finite element analysis models of a maxillary incisor with Re-Implant implants were made, surrounded by cortical and cancellous bone. A porcelain-fused-to-metal crown for the cpTi implant and a ceramic crown for the YPSZ implant were modeled. Stress levels were calculated according to the von Mises criteria. RESULTS: Higher stresses were observed at the area where the implant entered the bone. Stresses were higher at the facial and lingual surfaces than the proximal ones. In cortical bone and at the junction of cortical and cancellous bone, stress distribution presented a pattern of alternating higher (4.0 to 5.0 MPa) and lower (1.3 to 2.0 MPa) stress areas. Higher stresses were found at the apical third of the implant-to-bone junction as well. CONCLUSION: Re-Implant implants presented a pattern of low, well-distributed stresses along the entire implant-to-bone interface. YPSZ implants had very similar stress distribution to cpTi implants and may be viable esthetic alternatives, especially in maxillary anterior regions.

Ceramics↗

Curved beam model of the proximal femur for estimating stress using dual-energy X-ray absorptiometry derived structural geometry.

The investigation of individual differences in hip strength requires a method to measure structural geometry in vivo and a valid analytical approach to calculate mechanical stress. We developed a method for deriving structural geometry of the femur from the proximal shaft through the femoral neck, using data from dual energy X-ray absorptiometry. The geometric properties are employed in a two-dimensional curved beam model of the proximal femur to estimate stresses on the lateral and medial bone surfaces. Stresses calculated by this method are compared with those from the conventional flexure formula and with results produced from a cadaver femur with use of three-dimensional finite element analysis of computed tomography data. Loading conditions simulating a one-legged stance and a fall on the greater trochanter are employed. Stresses calculated by curved beam theory are in much better agreement with three-dimensional finite element analysis than are those for which the conventional straight beam formula was used. In simulation of a fall on the greater trochanter, all three methods show peaks of stress at the femoral neck but only the curved beam and finite element analysis methods show an additional peak at the medial intertrochanteric margin. Both neck and trochanter regions correspond to common failure sites for hip fractures in the elderly. The curved beam treatment of hip structure derived from dual-energy X-ray absorptiometry provides an approach for the in vivo engineering analysis of hip structure that is not practical by other methods.

Absorptiometry, Photon↗

[Finite element stress analysis of stress distribution endodontic posts at shoulder].

The objective of the present resarch is the comparative stress distribution of various design for post-core at shoulder. The purpose of this study was to analyse the stress distribution and concentration in the dentin of paralled-sided and taped posts by different shoulder designs with finite elements stress analysis method. It was found that stress tended to concentrate under the core shoulder with vertical force. When the force applied from the linqual side. The stress concentrated at the buccal side. The 90 degrees shoulder angles exhibited more even stress distribution than sharp shoulder angles. The analysis revealed that sharp angle should be avoided as occlusal shoulder in clinical practice because this design are less resistant to forces applied on them and are susceptible to fractures in the dentin.

Models, Biological↗

Contact finite element stress analysis of porous ingrowth acetabular cup implantation, ingrowth, and loosening.

Two-dimensional linear and contact finite element analyses were conducted of total hip arthroplasty using metal-backed, porous ingrowth acetabular components. The stress transmission characteristics from the component to the surrounding bone were given special attention. Resultant loads of 20 and 40 degrees medial of vertical were studied, and the influence of adding a metal flange to the rim of the cup was evaluated. The results indicated that when a conventional metal-backed component (without a flange) is initially implanted and subjected to normal loading, these components may experience distraction between the component and the surrounding bone at inferior sites. Compressive stresses in the superior dome cancellous bone, however, will be substantial. If complete porous ingrowth is achieved, the superior dome compressive stresses will be reduced and substantial shear stresses created. In addition, high local bone stresses were found at the component rim. If bone ingrowth is achieved only in specific locations, stress transmission will be dictated by those locations and may differ markedly from the case of complete bone ingrowth. In the event that no porous ingrowth is achieved and a fibrous layer forms around the component, the interface stresses will be similar to those calculated for the natural hip. The addition of a flange to the rim of the cup will reduce the magnitude of the radial stresses transmitted to the cancellous bone superiorly and medially by directly transferring some of the load to the lateral wall of the pelvis. The flange will also help to relieve the high local stresses that are found at the component rim.

Biomechanical Phenomena↗

Load transfer with the Austin Moore cementless hip prosthesis.

More than 1,300 Austin Moore hemiarthroplasties have been reviewed in the literature, with no reports of fracture of the stem. Many patients with these hip implants had good function. The lack of stem fractures in patients with good functions has not been explained and contrasts with stem fractures that have occurred in patients with cemented prostheses of other designs during the same time. We used three-dimensional finite-element analysis and free-body diagrams to explain the lack of fractures for this device by a description of the probable load-transfer mechanisms between the prosthesis and the bone. Results from our finite-element analysis indicate that, with good calcar-collar support, the stresses in the stem are small because the stem portion of the prosthesis and the bone are uncoupled and, consequently, do not share the resultant bending moment of the head and abductor forces. If the stem is coupled to the bone so that the resultant bending moment is shared, high stresses in the stem are predicted; such stresses are inconsistent with the complete absence of fractures of these prostheses. The results of the finite-element analysis further showed that loss of calcar-collar support with proximal fixation through the fenestrations resulted in high stresses in the stem and stress shielding of the proximal medial cortex. The uncoupled prosthesis also may be modeled with a free-body diagram as a three-force member loaded at the head, stem tip, and in the proximal region. With this model, it can be shown that the reaction force of the stem tip, and thus the peak bending stress in the stem, increases as calcar-collar support is decreased. If there is no calcar-collar support, proximal support must be provided by some combination of integration of bone in the fenestrations and wedging due to the lateral-medial taper of the device. Stresses in the stem are largest when there is no wedging, but high stresses develop in the cancellous bone in the fenestrations. When there is wedging, stresses in the stem can be low, but stresses in the supporting cancellous bone can be high; additional proximal support through the fenestrations substantially reduces these bone stresses. If reduced stresses in the cancellous bone are indicative of a stable device, these mechanisms indicate that fractures of the Austin Moore prosthesis have not occurred in normally loaded hips because load was transferred primarily either through the collar or by wedging, with additional support at the fenestrations.

Aged↗

The possibilities of uncemented glenoid component--a finite element study.

OBJECTIVE: (1) Determine the initial stress distributions within an uncemented implanted glenoid during elevation of the arm and to investigate whether failure is caused by stresses generated within this implant-bone structure. (2) Compare stress patterns between the uncemented design and two basic models of cemented prostheses. DESIGN: The uncemented component consists of a polyethylene cup with a metal-backing. All material interfaces were assumed to be fully bonded. BACKGROUND: Cemented glenoid components have been frequently vulnerable to failure within itself and at the cement-bone interface. A 3-D finite element analysis of an uncemented design is required to investigate whether clinical observations on failure can be better explained with a stress analysis. METHODS: A 3-D finite element submodel an uncemented prosthesis was generated using CT-scan data and realistic loading conditions (humeral abduction, 30-180 degrees ). The submodelling approach was based on an overall solution of a complete scapula acted upon by all muscles, ligaments and joint reaction forces. RESULTS: High Von Mises stresses (20-70 MPa) were generated in the metal-backing during abduction. Stresses were reduced in the polyethylene cup by 17-20% as compared to the cemented designs. Stresses in the underlying bone were substantially lower than to the natural glenoid. Stress-shielding can be observed in the trabecular bone underlying the prosthesis. The implant-bone interface is secure against interface failure at moderate loads, although the implant-bone (metal-bone) interface around the superior edge of the prosthesis is subject to high stresses (normal: 11.85 MPa, shear: 6.67 MPa) as compared to the cemented prosthesis. Whereas, the cement-bone interface, appears more likely to fail either at locations adjacent to the keel or at locations around the superior edge of the cemented design. The uncemented design therefore appeared to be a reasonable alternative to fixation with cement. RELEVANCE: Results of this study strongly agree with clinical and radiographic findings. Although indications of stress-shielding and separation of modular parts of the prosthesis were apparent, the implant-bone interface seems less likely to fail as compared to cemented designs. Once initial fixation of the implant is achieved, the uncemented design appears to have better prospects than cemented ones.

Equipment Failure Analysis↗

Characterization of in vivo strain in the rat tibia during external application of a four-point bending load.

This paper describes a technique for characterizing strains and stresses induced in vivo in the rat tibia during application of an external four-point bending load. An external load was applied through the muscle and soft tissue with a four-point bending device, to induce strain in a 11 mm section of the right tibiae of ten adult female Sprague-Dawley rats. Induced strains were measured in vivo on the lateral surface of the tibia. Inter-rat difference, leg positioning and strain gage placement were evaluated as sources of variability of applied strains. Beam bending theory was used to predict externally induced in vivo strains. Finite element analysis was used to quantify the magnitude of shear stresses induced by this type of loading. There was a linear relationship between applied load and induced in vivo strains. In vivo strains induced by external loading were linearly correlated (R2 = 0.87) with the strains calculated using beam bending theory. The finite element analysis predicted shear stresses at less than 10% of the longitudinal stresses resulting from four-point bending. Strains predicted along the tibia by finite element analysis and beam bending theory were well-correlated. Inter-rat variability due to tibia size and shape difference was the most important source of variation in induced strain (CV = 21.6%). Leg positioning was less important (CV = 9.5%).

Animals↗

Finite element scaling analysis of human craniofacial growth.

The study of form change is central to traditional cephalometric research. Unfortunately, traditional cephalometric studies operate within systems of measurement that are based on registration and orientation. Measurements produced in registered systems are insufficient for the craniofacial biologist who is interested in locating morphological differences between forms. In this article we apply a registration-free method called finite element scaling analysis in a study of the form change occurring during growth of the normal human craniofacial complex. The method provides form change data that can be summarized at various morphological levels. Twenty normal male individuals are used to analyze the form change that occurs from age 4 to ages 5, 7, 8, 9, 10, 12, 13, and 15 years. The magnitude and direction of growth expressed as shape and size change specific to craniofacial landmarks are presented. Although exceptions occur, our analysis shows that localized size change is, on the average, greater than localized shape change. The relation between size and shape change during growth shows allometry (shape change increasing during growth along with size change) but at a lesser magnitude and slower rate. We conclude that although shape change occurs throughout ontogeny, the magnitude and rate of shape change in relation to size change diminishes as age increases. This analysis represents new insights into the understanding of human craniofacial growth at various levels of morphological integration.

Adolescent↗

Finite element and Weibull analysis to estimate failure risk in resin-bonded retainers.

Three-dimensional finite element analysis and Weibull analysis were used to evaluate the effect of the thickness and the rigidity of the retainers on the risk of failure of an anterior resin-bonded prosthesis. Retainer thickness ranged from 0.4 to 1.4 mm. The physical properties of metals similar to Ni-Cr and type IV gold alloys were used. A concentrated load (100 N) was applied to the incisal edge of the finite element analysis modeled pontic, and the data of other loads (150 to 500 N in 50-N increments) were calculated from the data of 100 N. Subsequent Weibull analysis revealed that failure probability diminished when there was an increase in metal thickness at loads of 300 to 350 N, particularly for the retainer made of a type IV gold alloy. The reduction in failure probability caused by increasing the thickness of the metal was greater when type IV gold alloy was used than when Ni-Cr alloy was used. This investigation suggests that the longevity of resin-bonded retainers can be prolonged by thickening the retainers, rather than using more rigid metals.

Chromium Alloys↗