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Diet and blood pressure in children and adolescents.

Identifying dietary factors associated with blood pressure (BP) in children and adolescents would help guide recommendations for prevention of elevated BP, which is a major public health problem. This paper reviews 46 reports of studies examining relationships between dietary nutrients and BP in children and adolescents, many of which studied more than one nutrient. Sodium is the most extensively studied nutrient, with 25 observational and 12 intervention studies identified. Although many studies suffer from methodological problems, the results suggest that higher sodium intake is related to higher BP in children and adolescents. The results of 13 observational and 2 intervention studies of potassium and BP do not provide a clear picture of a relationship. The results of 8 observational and 1 intervention study of calcium and BP are inconclusive. Five observational studies of magnesium and BP provide evidence of an inverse relationship, but no intervention studies were identified. Nine studies of macronutrients and food groups or dietary patterns are inconclusive. Additional research is needed to provide more information about the relationships between dietary nutrients and BP in children and adolescents. Recommendations are provided for methodological features of additional research on diet and BP in children and adolescents.

Adolescent↗

Dietary shifts and implications for US agriculture.

Changes to healthier dietary patterns similar to those of traditional Mediterranean diets or those of the US government's dietary guidelines and food guide pyramid would require significant changes in American agricultural practices. The volume, mix, production, and marketing of agricultural commodities would need to be modified. Because differences between actual and recommended intakes for major food groups are quite large and affect a broad range of products, adjustments in supply and demand could overshadow past experience in dealing with such changes. New food and agriculture policies may well be needed to ease and accelerate agricultural adjustments, to improve nutritional characteristics of popular foods, and to promote desirable changes in consumers' food choices.

Agriculture↗

Translating the new dietary guidelines.

BACKGROUND: Diet- and nutrition-related diseases influence oral health. The U.S. government recently revisited the dietary guidelines for health promotion and chronic disease prevention. The purpose of this article is to review the new recommendations. CONCLUSIONS: The Dietary Reference Intakes are designed to identify nutrient intakes required to maintain health in people of a given age and sex. The Dietary Guidelines for Americans are designed to promote healthy dietary and activity habits. MyPyramid is designed to identify individual dietary patterns to ensure adequate nutrient intakes within energy needs. CLINICAL IMPLICATIONS: Familiarization with the new dietary guidelines will enable dental practitioners to develop diet-related oral health recommendations that are consistent with disease prevention.

Diet↗

Dietary glycemic index, glycemic load, and risk of incident breast cancer in postmenopausal women.

Insulin and insulin-like growth factor-I (IGF-I) are associated with increased risk of breast cancer in several studies. Circulating concentrations of insulin increase with dietary consumption of high glycemic index foods, which, in turn, may influence IGF-I levels or activity, but the relevance of such dietary patterns for breast cancer risk is unclear. We investigated whether consumption of carbohydrates with high dietary glycemic index would predict risk of postmenopausal breast cancer among 63,307 United States women in the Cancer Prevention Study II Nutrition Cohort. From baseline in 1992, participants 40-87 years of age and free from cancer and diabetes, were followed for 5 years; 1442 incident breast cancer cases were documented. Diet was assessed at baseline by a validated 68-item food frequency questionnaire from which we calculated dietary glycemic index and glycemic load. Dietary glycemic index and load were not associated with increased risk of postmenopausal breast cancer (rate ratio = 1.03; 95% confidence interval, 0.87-1.22 and rate ratio = 0.90; 95% confidence interval, 0.76-1.08, respectively) after adjustment for multiple breast cancer risk factors. Associations were not modified by body mass index, physical activity, hormone use, or stage of disease. Future evaluations of glycemic index and breast cancer risk may be strengthened by longer follow-up, more complete dietary information, and measurement of plasma insulin and IGF-I levels.

Adult↗

Relationship of dietary regimens to success, efficiency, and cost of weight loss.

One hundred twenty-five subjects in a behaviorally oriented, weight loss program that used several dietary patterns were retrospectively grouped according to the percentage of time they followed one of four dietary regimens: (a) Group 1--partial fasting, 400 kcal; (b) group 2--600 kcal; (c) group 3--1,200 to 1,500 kcal; and (d) group 4--failure to diet. The groups were described and compared regarding program completion, i.e., success and cost of weight loss. Groups 1 and 2 did significantly better than the other two in nearly all respects. Group 1 did better than Group 2 on program completion; the reverse was true when success of those completing 75 and 100 per cent of the program was compared. Groups 1 and 2 did not differ significantly on success variables.

Adult↗

The relationship of diet to airsickness.

This descriptive, correlational study examined meal frequencies and dietary intakes as they related to airsickness in a population of novice civilian pilots. Food and nutrient intakes and dietary patterns of pilots prior to flight were measured for association with airsickness. A 24-h dietary recall was used in recording dietary intake and meal frequencies during a typical flight day. Correlation analysis was used to determine relationships between dietary intake and airsickness. Of the female pilots, 75% experienced airsickness; and 24% of the male pilots experienced it. Female pilots' mean 24 h dietary intakes of vitamins A, C, and iron were low. The findings indicate eating high sodium foods (r = 0.33, p = 0.02) such as preserved meats, corn chips and potato chips, and eating foods high in thiamin (r = 0.35, p = 0.01) like pork, beef, eggs, or fish correlated significantly with increased airsickness. Consumption of foods high in protein such as milk products, cheeses and preserved meat by the males correlated significantly (r = 0.28, p = 0.05) with increased airsickness. The frequency of meals eaten during the day also correlated with increased airsickness. Of the airsick pilots, 75% consumed three or more meals in the previous 24 h, as compared to 41% of the nonairsick pilots. Higher density foods (more kilocalories) also increased the airsickness occurrences of both the male and female pilots.

Adolescent↗

Nutrient intakes of whites, blacks, and Mexican Americans in southeast Texas.

Ethnic groups in the United States exhibit different patterns of cardiovascular disease and cancer morbidity and mortality. This has, in part, been attributed to differences in dietary intake. However, there is limited comparative information available regarding the dietary patterns of whites, blacks, and Hispanics residing in the same geographic area. Selected nutrient intakes were obtained by an interviewer-administered 24-hr dietary recall from 231 white, 102 black, and 98 Mexican-American persons residing in the same communities in Southeast Texas. Mean caloric intakes were highest for whites, followed by Mexican Americans and blacks. Mexican Americans had carbohydrate intakes that were significantly higher, but total fat intakes that were significantly lower, than those of whites. Blacks of both sexes had the highest cholesterol intakes and black males had the highest saturated fat intakes. Neither was significantly higher than that of whites or Mexican Americans. Overall, the mean vitamin A and C values were highest for blacks and lowest for whites, although the differences were not statistically significant. Mean calcium and phosphorus intakes were significantly higher for whites compared with those for blacks and Mexican Americans. Blacks had significantly lower mean fiber values than whites or Mexican Americans. International ethnic differences in disease distribution have long been used to provide clues to etiologic factors. National ethnic differences in disease distribution related to dietary intake can further elucidate these causative and/or preventive factors. However, to do so will require additional attention to dietary methodology of the type presented here.

Adult↗

Nutrition and health: patterns and policy perspectives in food-rich countries.

Nutrition and health are becoming legitimate policy issues in food-rich countries. Dietary patterns contribute to a large share of the dominant chronic disease profile in advanced industrial nations, burdening the public purse. Major issues facing governments concern decisions about the appropriate goals, scope, and instruments for effective policy, and the apparatus to promote it. Norway, using a long term, explicit and comprehensive public policy, and the U.S., using a market-oriented strategy, illustrate contrasting policy approaches to the issues. The experience of both have implications for current policy-making in other countries and for the kind of research needed to support it.

Feeding Behavior↗

[Study on the food consumption pattern of elderly people in four "cuisine" areas of China].

In order to investigate the situation of food intake, diet habit and dietary pattern in people living in different "cuisine" areas of China, and to search for the relations between diet and health status, a total of 538 subjects (269 couples) aged between 50-60 years in four rural areas were surveyed by a food frequency questionnaire method. Selected items of food consumption pattern and food intake of the subjects were analyzed. The results showed significant differences on food intake among the people in the four cuisine areas. This study provided references for the future study on the relationship between diet and health.

Aged↗

Optimal diets for prevention of coronary heart disease.

CONTEXT: Coronary heart disease (CHD) remains the leading cause of mortality in industrialized countries and is rapidly becoming a primary cause of death worldwide. Thus, identification of the dietary changes that most effectively prevent CHD is critical. OBJECTIVE: To review metabolic, epidemiologic, and clinical trial evidence regarding diet and CHD prevention. DATA SOURCES AND STUDY SELECTION: We searched MEDLINE through May 2002 for epidemiologic and clinical investigations of major dietary factors (fat, cholesterol, omega-3 fatty acids, trans-fatty acids, carbohydrates, glycemic index, fiber, folate, specific foods, and dietary patterns) and CHD. We selected 147 original investigations and reviews of metabolic studies, epidemiologic studies, and dietary intervention trials of diet and CHD. DATA EXTRACTION: Data were examined for relevance and quality and extracted by 1 of the authors. DATA SYNTHESIS: Compelling evidence from metabolic studies, prospective cohort studies, and clinical trials in the past several decades indicates that at least 3 dietary strategies are effective in preventing CHD: substitute nonhydrogenated unsaturated fats for saturated and trans-fats; increase consumption of omega-3 fatty acids from fish, fish oil supplements, or plant sources; and consume a diet high in fruits, vegetables, nuts, and whole grains and low in refined grain products. However, simply lowering the percentage of energy from total fat in the diet is unlikely to improve lipid profile or reduce CHD incidence. Many issues remain unsettled, including the optimal amounts of monounsaturated and polyunsaturated fats, the optimal balance between omega-3 and omega-6 polyunsaturated fats, the amount and sources of protein, and the effects of individual phytochemicals, antioxidant vitamins, and minerals. CONCLUSIONS: Substantial evidence indicates that diets using nonhydrogenated unsaturated fats as the predominant form of dietary fat, whole grains as the main form of carbohydrates, an abundance of fruits and vegetables, and adequate omega-3 fatty acids can offer significant protection against CHD. Such diets, together with regular physical activity, avoidance of smoking, and maintenance of a healthy body weight, may prevent the majority of cardiovascular disease in Western populations.

Coronary Artery Disease↗

Structured dietary advice incorporating walnuts achieves optimal fat and energy balance in patients with type 2 diabetes mellitus.

OBJECTIVE: A cardioprotective dietary fat profile is recommended for the treatment of type 2 diabetes. The clinical feasibility of advice strategies targeting specific fatty acid intakes and the extent to which they can be achieved by free-living populations needs to be tested. Walnuts, with high n-3 polyunsaturated fatty acid (PUFA) content, may help optimize fatty acid intakes, but regular consumption might increase total fat and energy intakes. This study examined whether advice that refers to a total dietary pattern inclusive of walnuts would result in low-fat energy-controlled diets with optimal dietary fat proportions for patients with type 2 diabetes mellitus. RESEARCH DESIGN AND METHODS: A parallel-design, controlled trial was completed by 55 free-living men and women with established type 2 diabetes mellitus. Participants were randomly assigned to one of three groups: low-fat (general advice), modified low-fat (total diet advice using exchange lists to differentiate PUFA-rich foods), walnut-specific (modified low fat including 30 g walnuts/day). Dietary intakes and clinical outcomes were measured at baseline, and at 3 and 6 months. Dietary goals were: less than 10% of energy from saturated fat, 7% to 10% of energy from PUFA, adequate n-3 PUFA (>or=2.22 g alpha-linolenic acid, >or=0.65 g eicosapentaenoic acid [EPA]+docosahexaenoic acid [DHA]) and n-6 to n-3 ratio less than 10. The proportion of subjects achieving dietary goals and major food sources of fat were determined. RESULTS: At baseline, dietary intakes were not significantly different between groups. No group and few individuals (10%) were consuming adequate PUFA, with meat the main source of dietary fat (22% total dietary fat). At 3 and 6 months, energy and macronutrient intakes were similar among groups. The walnut group, however, was the only group to achieve all fatty acid intake targets (P <.01), and had the greatest proportion of subjects achieving targets ( P <.05). Walnuts were the main source of dietary fat (31%) and n-3 PUFA (50%), while 350 g oily fish/day provided a further 17% n-3 PUFA consumed by this group. CONCLUSIONS: Specific advice for the regular inclusion of walnuts in the context of the total diet helps achieve optimal fat intake proportions without adverse effects on total fat or energy intakes in patients with type 2 diabetes mellitus.

Adult↗

The Interdepartmental Committee on Nutrition for National Defense surveys: lasting impacts.

The Interdepartmental Committee on Nutrition for National Defense (ICNND) Surveys provided previously unavailable representative information on the food and nutrition situations of military or civilian populations in 33 developing countries. Information on related social and economic conditions also were assessed. These data provided a framework for planning follow-up programs to correct problems identified and to prevent them from recurring, such as fortification of salt with iodine and sugar with vitamin A. Educational materials specific to the nutrient content of local foods, dietary patterns, and availability within countries and cultures were also developed, such as food composition tables and dietary guidelines. In-country scientists were motivated to continue nutrition research, and, in several countries, institutes and departments of nutrition evolved. Impact was documented by improved nutritional status in several countries, although success is not always attributed directly to the impetus provided through the ICNND Surveys. Furthermore, the surveys and their leaders provided inspiration and role models for aspiring young nutritionists both within their own countries and internationally.

Dietary Supplements↗

The influence of diet on urinary risk factors for stones in healthy subjects and idiopathic renal calcium stone formers.

The daily intake of 103 recurrent idiopathic calcium stone formers and 146 controls was assessed by means of a computer-assisted 24-h dietary record. Timed 24-h urine samples were collected over the same period to assess the relationship between dietary intake of nutrients and urinary risk factors for calcium stones. After standardisation for sex, age and social status a total of 128 subjects underwent final statistical analysis; 64 renal stone formers and 64 controls. Significant increases in the consumption of animal and vegetable protein and purine were identified as the nutritional factors that distinguished renal stone formers from controls. As expected, the daily urinary excretion of calcium and oxalate was higher and the daily urinary excretion of citrate was lower in stone formers than in controls. No difference with respect to daily urinary uric acid excretion was recorded. Daily urinary excretion of calcium was correlated to dietary protein intake while daily urinary oxalate was correlated to dietary vitamin C intake. It was concluded that renal stone formers could be predisposed to stones because of their dietary patterns. A link between the protein content of the diet and urinary calcium was confirmed, but dietary animal protein had a minimal effect on oxalate excretion.

Adult↗

The nutrient content of the Italian food supply 1961-1992.

OBJECTIVE: To highlight the methodology used to determine nutrient per capita per day values, to report values for food energy and 12 nutrients and to compare these values with FAO nutrient per capita values and Recommended Dietary Intakes (RDIs) for Italy. DESIGN: The nutrient content of the Italian food supply was calculated using food per capita data from FAO and food composition data from the Italian National Nutrition Institute. RESULTS: All nutrient per capita values have increased since 1961 except carboyhdrate. Wheat-based products were important sources of thiamin, riboflavin, niacin, phosphorus, iron, and potassium; and vegetables were predominant sources of vitamin A, ascorbic acid, riboflavin, niacin, calcium, iron, and potassium. The increase in red meats has accounted for some of the increases in fat, protein, vitamin A, thiamin, riboflavin, niacin, phosphorus, and iron. FAO reported higher values for energy, fat and niacin and lower values for protein, ascorbic acid, riboflavin, thiamin, calcium in all years. The trends for vitamin A and iron were similar in both data sets; however, there were switches in which set reported higher values. The trends for niacin and calcium were not similar. When compared with the RDIs, most of the nutrients were adequate. The exceptions were iron for females ages 10-59 and calcium for adolescents. CONCLUSION: Different nutrient values and sometimes trends resulted when nutrient composition data and edible portion factors specific to Italy were used to determine nutrient per capita values. The nutrient content of the Italian food supply changed between 1961 and 1992, suggesting dietary patterns in Italy also changed.

Adolescent↗

Towards a systems biology understanding of human health: interplay between genotype, environment and nutrition.

Sequencing of the human genome has opened the door to the most exciting new era for the holistic system description of human health. It is now possible to study the underlying mechanisms of human health in relation to diet and other environmental factors such as drugs and toxic pollutants. Technological advances make it feasible to envisage that in the future personalized drug treatment and dietary advice and possibly tailored food products can be used for promoting optimal health on an individual basis, in relation to genotype and lifestyle. Life-Science research has in the past very much focused on diseases and how to reestablish human health after illness. Today, the role of food and nutrition in human health and especially prevention of illness is gaining recognition. Diseases of modern civilization, such as diabetes, heart disease and cancer have been shown to be effected by dietary patterns. The risk of disease is often associated with genetic polymorphisms, but the effect is dependent on dietary intake and nutritional status. To understand the link between diet and health, nutritional-research must cover a broad range of areas, from the molecular level to whole body studies. Therefore it provides an excellent example of integrative biology requiring a systems biology approach. The current state and implications of systems biology in the understanding of human health are reviewed. It becomes clear that a complete mechanistic description of the human organism is not yet possible. However, recent advances in systems biology provide a trajectory for future research in order to improve health of individuals and populations. Disease prevention through personalized nutrition will become more important as the obvious avenue of research in life sciences and more focus will need to be put upon those natural ways of disease prevention. In particular, the new discipline of nutrigenomics, which investigates how nutrients interact with humans, taking predetermined genetic factors into account, will mediate new insights into human health that will finally have significant positive impact on our quality of life.

Environment↗

The effect of Indian or Anglo dietary preference on the incidence of diabetes in Pima Indians.

OBJECTIVE: In short-term studies, adoption of a traditional diet is associated with reduction in metabolic abnormalities often found in populations experiencing rapid lifestyle changes. We examined the long-term effects of a self-assessed traditional or nontraditional dietary pattern on the development of type 2 diabetes in 165 nondiabetic Pima Indians. RESEARCH DESIGN AND METHODS: Dietary intake was assessed in 1988 by a quantitative food frequency method, and subjects were asked to classify their diet as "Indian," "Anglo," or "mixed." The Indian diet reflects a preference for Sonoran-style and traditional desert foods. The Anglo diet reflects a preference for non-Sonoran-style foods typical of the remaining regions of the U.S. RESULTS: In women, the intake of complex carbohydrates, dietary fiber, insoluble fiber, vegetable proteins, and the proportion of total calories from complex carbohydrate and vegetable proteins were significantly higher (P < 0.05) in the Indian than in the Anglo diet. The mixed diet was intermediate in of all these constituents. In men, the intake for these nutrients was also higher in the Indian than in the Anglo group, but not significantly. Diabetes developed in 36 subjects (8 men and 28 women) during 6.2 years of follow-up (range 0.9-10.9). The crude incidence rates of diabetes were 23. 35, and 63 cases per 1,000 person-years in the Indian. mixed, and Anglo groups, respectively. After adjustment for age, sex, BMI, and total energy intake in a proportional hazards model, the risk of developing diabetes in the Anglo-diet group was 2.5 times as high (95%) CI 0.9-7.2) and the rate in the mixed-diet group was 1.3 times as high (0.6-3.3) as in the Indian-diet group. CONCLUSIONS: This study suggests that the adoption of an Anglo diet may increase the risk of developing diabetes in Pima Indians, but it does not provide unequivocal evidence for or against this hypothesis.

Adolescent↗

Studies on the effect of feeding nitrite and secondary amines to Wistar rats.

1. When 1 000 mg/l sodium nitrite are added to drinking-water, nitrosamines are formed in the stomachs of Wistar rats at levels greater than the background only if the concentrations of added DMA or pyrrolidine exceed 1 000 mg/kg. Once this concentration is exceeded there is a rapid increase in nitrosamine formation up to 2 000 mg/kg added amine; however, for pyrrolidine, the rate of increase of NPy decreases when the dietary level of amine exceeds 2 000 mg/kg. This threshold level of 1 000 mg/kg amine is one which is rarely reached in normal human dietary patterns. 2. Due to the presence of this threshold it is unrealistic to extrapolate from high experimental dietary concentrations of secondary amines to those found in practice when considering nitrosamine formation in vivo. 3.The concentration of dietary amine has a greater influence on nitrosamine formation in the stomachs of rats than does the concentration of nitrite in drinking-water (up to 1 000 mg/l). This finding is in contradiction to the current kinetic theory of nitrosamine formation, in which formation is predicted to be proportional to the square of the nitrite concentration.

Animals↗

Dietary fiber intake and dental health status in urban-marginal, and rural communities in central Mexico.

INTRODUCTION: Oral health status in older people is frequently poor which can contribute to inadequate dietary patterns and nutrition status. OBJECTIVE: To investigate whether an association between the number of teeth present and dietary fiber intake exists in elderly people living independently, across different geographic and socioeconomic locations. METHODS: A cross-sectional household survey was undertaken in three Mexican communities (urban, marginal urban, and rural), incorporating geographic and socio-demographic information and a 24-hour diet recall. Dental status (teeth present, coronal and root caries, and periodontal status) was determined by clinical examination. Data were analyzed using ANOVA, Pearson's chi2 and Tukey's range tests. RESULTS: 407 persons 60 years old and over participated in the study. Subjects in the rural community had better dental/periodontal status and more teeth present than urban and marginal-urban participants. Intake of fiber was 8.4 g/day for the urban, 7.6 g/day for the marginal-urban, and 13.5 g/day for the rural community. While gender had no detectable effect, the location of residence and the number of teeth present were associated with mean fiber intake; having more than 21 teeth and/or living in a rural location were associated with increased mean fiber intake.

Age Distribution↗