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At least 793 records · Page 44Linked to original sources
PubMed1989

[Squamous cell carcinoma of the conjunctiva].

Squamous cell carcinoma of the conjunctiva is the most frequent nonpigmented malignant conjunctival tumor and often misdiagnosed. Chronic unilateral keratoconjunctivitis should be biopsied to rule out malignancy. The authors report 11 cases treated by complete excision with biopsy. 7 cases were followed up 3 months to 7 years without relapse. Beta-irradiation is recommended for cases suspected of incomplete excision. The incidence, pathological classification, diagnosis, differential diagnosis, treatment and lymphatic metastasis of the disease have been discussed and the significance of periodical follow-up emphasized.

Aged↗
PubMed1988

[A case of fibrous histiocytoma of the conjunctiva].

The case of a 49-year old woman who developed fibrous histiocytoma of the conjunctiva is reported. Clinically, the lesion was tumoral, unpigmented and located in the corneo-scleral limbus. The lesion was excised, and the patient remained cured throughout the 4-year follow-up. Five other cases have been published, and in all of them cure without recurrence was obtained by excision.

Conjunctival Neoplasms↗
PubMed1988

Approach to a dark spot on the conjunctiva.

Although malignant melanoma most often develops in the skin, it can also arise in several layers of the eye. Therefore, new dark brown or black spots on the conjunctiva must be recognized during physical examination and then evaluated. When melanoma is suspected, there should be no hesitation in performing excisional biopsy under local anesthesia. The differential diagnosis includes melanocytic nevi and primary or secondary melanosis.

Adrenal Insufficiency↗
PubMed1987

Cystic lesions of conjunctiva.

Cystic lesions constituted 37% of all the conjunctival specimens received over a period of 6 1/2 years. Epithelial inclusion cysts were the most common, followed by dermoid and parasitic cysts. A clinicopathologic correlation, along with an attempt at classification of cystic lesions of conjunctiva, is made in this article.

Adolescent↗
PubMed1987

[Worm infection (Dirofilaria conjunctivae) in the ENT area].

In 1984 was detected a 5 cm long worm in the eyelid of a 49 year old woman. This worm was classified as Dirofilaria conjunctivae. The woman had spent her holidays previously in Italy, Spain and Yugoslavia and in one of these countries she might be worm-infected by a mosquito bite. No further nodules were seen in the subskin after the operation and the blood control parameters remained normal. Only the persistent antibodies convey the idea of a previous worm infection. Today the patient is considered to be healthy.

Animals↗
PubMed1987

Extensive squamous cell carcinoma of the conjunctiva presenting as orbital cellulitis: the hermit syndrome.

The authors present three cases of extensive squamous cell carcinoma of the conjunctiva invading the orbit and masquerading as orbital cellulitis. All cases were in elderly alcoholic men living in relative social isolation. Total exenteration of the orbit was required in all three cases. Only one patient has had long-term follow-up; he was well 5 years after presentation. The other two patients were well 15 and 5 months after surgery.

Aged↗
PubMed1985

[Melanic proliferations of the conjunctiva. Histopathologic study of a series of 40 cases].

A retrospective study of 40 melanocytic conjunctival tumors (22 naevi and 18 malignant melanoma) is reported. Cases of non-degenerated conjunctival melanosis were not observed. The particular aspects of diagnosis and the prognostic behaviour of these proliferations are discussed and compared with their cutaneous homologues. Epithelial inclusions within tumor cell proliferation are considered as the best criterion of benignity. Because conjunctival melanomas are rather uncommon and technical difficulties in their study are very frequent (poor quality of tissue samples, small size of specimens) many reports are contradictory. Some diagnostic signs are specific for this kind of tumor in the conjunctiva: nevertheless, the particular conjunctival anatomy makes it impossible to classify according to criteria defined for cutaneous malignant melanoma. No criteria would have a predictive value. The severe prognosis of conjunctival melanoma (44% deaths in the present series over 10 years after diagnosis) has been underestimated. Most often carcinologic therapies have not been used in previously reported cases.

Adolescent↗
PubMed1983

[Mucoepidermoid carcinoma of the conjunctiva. Clinical, histologic and ultrastructural study].

Four cases of muco-epidermoid carcinoma of the conjunctiva are described, with an electron microscopy study in one case. Three patients were over 70 years and the fourth one 39 years old. In all cases, the tumor was primarily located close to the limbus and appeared as a quiescent corneoscleral ulcer or as a diffuse limbal thickening. Histologically, they showed an admixture of epidermoid and mucus secreting cells on alcian blue staining, and this was confirmed by electron microscopy. These tumors appear to be locally aggressive and rapidly recurring, and they invade the intra-ocular structures and/or orbit. One patient died 6 years after the onset of the disease. Prognosis is therefore poor and the lesion requires early treatment by wide local excision and a strict follow up for early detection of any recurrence.

Adult↗
PubMed1982

Radiation therapy in amyloidosis of the eyelid and conjunctiva: a case report.

Many questions about amyloidosis are still unanswered. Etiology and pathogenesis remain unclear. Diagnosis is difficult to prove without a biopsy. Several approaches have been tried, but no effective cure has been documented. Russian authors report the use of cobalt therapy for a patient with local laryngeal amyloidosis. This paper presents a case report of a patient with local amyloidosis of the conjunctiva. Superficial radiation therapy was used, and resulted in some shrinkage of the lesions. Surgical excision was later utilized to remove the remaining amyloid deposits.

Aged↗
PubMed1982

[Malignant melanoma of the conjunctiva and eyelids: analysis of prognosis in 56 cases (author's transl)].

Long-term prognosis was analyzed by a retrospective study of 56 patients with malignant melanoma of the conjunctiva and the eyelids. Survival rate at 5 years was 85 p. cent, at 10 years 68 p. cent, and at 15 or 20 years 55 p. cent; neither the localization of the tumor nor the type of initial treatment had a significant influence on these rates. Local or nodal recurrences occurred in 80 p. cent of cases, and were frequent following conservative surgery; prognosis is bad after radiotherapy.

Adolescent↗
PubMed1982

Kaposi's sarcoma involving eyelid and conjunctiva.

This is a case report of Kaposi's sarcoma involving the eyelid an conjunctiva in a man of North American Indian descent. Ocular involvement is rare and has been documented in less than 30 cases in the world literature. The association with visceral lesions and resultant poor prognosis was discussed and illustrated in our patient. Treatment of the eyelid lesion consisted of surgical excision; follow-up observation was limited to four months, as the patient died of a gastrointestinal malignancy.

Adenocarcinoma↗
PubMed1982

Carbon dioxide laser therapy of recurrent squamous papilloma of the conjunctiva.

Juvenile squamous papilloma of the conjunctiva may exhibit "malignant" behavior with multiple recurrences presenting difficulty in management. We have successfully treated a child with the carbon dioxide laser who had failed three previous surgical excisions, cryotherapy (twice), and chemotherapy. The carbon dioxide laser permits a precise form of tissue excision with minimal trauma, edema, and scarring, and offers a safe alternative approach to the management of these lesions.

Child, Preschool↗
PubMed1980

Prolapse of conjunctiva following external levator resection.

Prolapse of the conjunctiva from the superior cul-de-sac is an infrequent complication following external levator resection. In uncooperative patients or children, repositioning of the prolapsed fold of tissue may be difficult and result in a fused conjunctival fold. This complication occurred in 4 of 102 children of the authors' series; its management is outlined.

Blepharoptosis↗
PubMed1994

The identification of Mycoplasma conjunctivae as an aetiological agent of infectious keratoconjunctivitis of sheep in South Africa.

Ovine keratoconjunctivitis was successfully reproduced in lambs under 1 year of age, in four separate transmission trials, by the use of mycoplasma isolates obtained from field outbreaks of ovine infectious keratoconjunctivitis. Mycoplasma isolates used in one of these trials, were identified as M. conjunctivae by means of immunofluorescence. Mycoplasma was isolated from approximately 87% of field cases examined. Branhamella ovis was isolated from 22% of field cases examined. No Chlamydia sp. or viruses were isolated from any of the outbreaks.

Animals↗
PubMed1995

Myxoma of the conjunctiva: a case report and a review of the literature.

A rare case of conjunctival myxoma is reported. A painless tumor was noted in the left bulbar conjunctiva of an 80-year-old woman. The extirpated tumor, 12 x 10 mm, was hypocellular and composed of spindle-shaped or stellate tumor cells. The tumor stroma showed extensive myxomatous changes. Alcian blue stain with hyaluronidase digestion revealed that the matrix contained rich amounts of hyaluronidase-sensitive acid mucopolysaccharides. Immunohistochemically, the tumor cells were positive for vimentin and alpha-smooth muscle actin, suggesting a fibroblastic or myofibroblastic cell phenotype. A review of the literature revealed the rare incidence and invariable benign behavior of conjunctival myxoma.

Actins↗
PubMed1995

[Incidence of tumors and tumor-like lesions in the conjunctiva and the cornea].

Incidence of tumors and tumor-like lesions in conjunctiva and cornea seen at Juntendo University during the 13-year period from 1980 to 1992 was analysed histopathologically. There were 126 cases including 116 benign (92.1%) and 10 malignant lesions (7.9%). Pigmented nevi (32 cases) were most frequently found, accounting for 27.6% of the benign tumors and tumor-like lesions, half of which were compound nevi (16 cases). Nevi were closely followed by cysts (24 cases, 20.7%) and dermoids (15 cases, 12.9%). Carcinoma in situ (3 cases) was most frequently found, accounting for 30% of the malignant tumors (10 cases), closely followed by malignant lymphoma (2 cases), squamous cell carcinoma (2 cases), mucinous carcinoma (1 case), sebaceous gland carcinoma (1 case) and metastatic tumor (1 case). The ratio of males to females was 4:6. Age distribution of the patients was 47-92 years.

Adolescent↗