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PubMedDate not supplied

[Computer analysis of erythrocyte catalase activity in diagnosis of mild brain trauma and concussion].

A complex investigation of catalase activity in erythrocytes was conducted basing on the results of computer quantitative morphometry of histochemical examination of blood samples from persons with mild craniocerebral trauma. It was found that erythrocytic catalase activity correlates with severity of brain trauma. A novel technique of objective histochemical diagnosis of trauma is described. It provides objective grounds for expert conclusions. Differential features of erythrocytic shape were defined in a small series of micropreparations vs the rest blood samples.

Brain Concussion↗
PubMed1991

[The superoxide dismutase activity of the brain and liver tissues in a rabbit with an experimental brain concussion].

A study is presented of the activity of superoxidedismutase and catalase in the brain and liver in the dynamics of mild head injury in experiments on rabbits. It was established that the activity of catalase in the brain show a three-times reduction within 15 minutes after the injury. The catalase activity in the liver remains practically unchanged. The activity of superoxidedismutase in the liver in the posttraumatic period does not differ from control values. In the brain superoxidedismutase activity reduces by 38% only on the 7 and 14 days after injury.

Animals↗
PubMed1990

[Long-term transcranial Doppler ultrasound monitoring in increased cerebrospinal fluid pressure caused by brain concussion].

Blood flow velocities of the basal cerebral arteries were studied by transcranial Doppler sonography in a 6 year old girl, comatous after cerebral contusion. Under progressive increase of cerebral pressure, Doppler sonographic long-term monitoring of the middle cerebral artery was performed parallel to the intracranial pressure until dissociated brain death. The results correlated closely with the cerebral perfusion pressure. Even before onset of the excessive increase in cerebral pressure no hyperventilation effect was seen in the contusion foci. Transcranial Doppler sonography represents an additional monitoring method for further improvement of treatment of severe head injuries.

Blood Flow Velocity↗
PubMed1990

[Changes in human cerebral cortex in various areas of concussion in severe cranio-cerebral injury].

In 23 patients with a severe cranial-cerebral trauma the operative material (pieces of the cortex, obtained from the destructive, transitional and relatively preserved zones in the bruise foci with crushing, localized in various lobules of the cerebral hemispheres) has been studied. From 2 h up to 9 days after trauma, changes, characterizing the state of the vascular bed, nervous and glial cells have been followed. In the external area of the transitional zone in 15 patients and in the relatively preserved zone in all the patients reversibly altered nervous cells predominate. Only in the destructive zone in all 23 patients and in the whole transitional zone in 8 patients neurons in all cortical layers are deeply injured and unviable. Certain considerations on differential surgical tactics, when treating the bruise foci with crushing at a severe cranial and cerebral trauma are presented.

Adult↗
PubMed1990

[Deontological aspects of the diagnosis and treatment of patients with a history of brain concussion].

Follow-up and therapeutic data obtained for 200 patients at the age of 15-75 who had a craniocerebral injury lead the author to the conclusion on the specificity of the deontological approach in acute and subsequent periods of the trauma. Due attention should be paid to the patients' premorbid status, pre-existent chronic somatic and neurological diseases, age, individual characteristics of the injury and personality traits.

Adolescent↗