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Results for “Cardiomyopathy, Restrictive”

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At least 793 records · Page 44Linked to original sources
PubMed1986

Multimodality approach to pericardial imaging.

In this chapter, three modalities--computed tomography, nuclear magnetic resonance imaging, and echocardiography--have been discussed. Each of these techniques offers unique advantages in the diagnosis of pericardial disease. Although echocardiography is the least expensive, most sensitive, and least invasive technique for the identification of pericardial effusion, false-positive and negative studies may be encountered. These are often resolved with the use of computed tomography and may be resolved with magnetic resonance imaging. Plain film radiography still has the advantage of identifying pericardial calcifications and will suggest the diagnosis of large pleural effusions at low cost and radiation dose. Exquisite portrayal of cross section anatomy using CT will aid in the diagnosis of multiple small tumor deposits and will clearly identify pericardial thickening. The value of magnetic resonance imaging awaits carefully controlled blinded studies, but its role in characterization of the content of pericardial effusions appears especially promising.

Cardiomyopathy, Restrictive↗
PubMed1987

HLA investigations in cardiomyopathies.

Typization of HLA A, B and C antigens of peripheral lymphocytes was performed in 14 patients suffering from cardiomyopathy and in 10 family members from 10 families. Among the antigens of locus A, the most frequent were the subgroups of HLA A9 (A23 and A24) in 7/14, and those of HLA A10 (A25 and A26) in 3/14; frequent antigens of locus B were the types B5, B7, B12 and B35. In 2 of 10 families the cardiomyopathy was transmitted by autosomal dominant genes, while the other cardiomyopathy cases were sporadic. The HLA B8 antigen was not observed in any case of cardiomyopathy.

Adolescent↗
PubMed1987

Idiopathic cardiomyopathies. A review of pathologic studies and mechanisms of pathogenesis.

The purpose of this article is to provide a critical review of our current knowledge of the pathogenic mechanisms of human cardiomyopathy in the context of accepted morphologic findings (gross, microscopic, ultrastructural) and the clinical presentation of this disease. It is our intent to emphasize the numerous difficulties encountered in categorizing patients with cardiomyopathy to pursue investigations in the pathogenesis and origins of this puzzling cardiac condition. It is our belief that such difficulties stem primarily from the existing classification of cardiomyopathies, which is mostly empirical and somewhat vague. This is particularly true in regard to the dilated cardiomyopathies that probably encompass multiple entities grouped under the umbrella of cardiomegaly and dilation. The article's objective is to summarize clinical symptoms and signs, modalities of diagnostic investigations, and prognosis for each category of cardiomyopathy. However, the main purpose of this article is to present recent findings on the origins, possible autoimmune basis of the disease, and results of immunologic studies in patients with cardiomyopathy.

Antibody Formation↗
PubMed1995

[Myocardial diseases: lessons from the past and future prospects].

This report provides an overview of current concepts on the cardiomyopathies. They constitute a heterogeneous group of diseases with complex interrelations between clinical manifestations, pathophysiology and therapy. Special emphasis was made to review new advances on the diagnosis and current management of patients with hypertrophic cardiomyopathy. The link between the classical knowledge and recent--still evolving--ideas is addressed to provide the--state of the art--concerning the implications on the clinical decision making process. Controversial issues such as diagnostic criteria, prognostic features and implications of electrocardiographic and echocardiographic data are revisited in brief. Data suggesting the value of dual chamber pacing as a means to relieve outflow tract obstruction and to improve symptoms in patients with hypertrophic cardiomyopathy are discussed. The molecular basis of this entity together with the characterization of the responsible genetic mutations are reviewed in detail.

Adolescent↗
PubMedDate not supplied

Heterotopic heart transplantation for elevated pulmonary vascular resistance in pediatric patients.

BACKGROUND: The presence of significant elevation of pulmonary vascular resistance is a major risk factor for death after orthotopic heart transplantation. The choice of procedure for the pediatric patient remains contentious. METHODS: We report three pediatric patients with pulmonary hypertension and raised pulmonary resistance, including two infants, in whom heterotopic transplantation was performed with smaller donor hearts. The hearts were anastomosed to provide left ventricular support alone because predominant left ventricular failure was present, the pulmonary resistance was expected to fall gradually after surgery, and we wished to avoid the potential problems of a pulmonary conduit associated with growth and possible reoperation. RESULTS: The clinical results have been satisfactory in all three patients, who were well and without symptoms. No pulmonary compromise was observed in the smaller thoracic cavity of the two infants. The transpulmonary gradient fell in all three patients, although this reduction was not immediate. CONCLUSIONS: This technique in carefully selected recipients can allow safer transplantation in pediatric patients with elevated pulmonary resistance, can increase the donor pool by allowing use of smaller hearts and nonideal donors, and may reduce the mortality on the transplant waiting list by providing earlier transplantation.

Adolescent↗
PubMed1994

[Contribution of magnetic resonance imaging to the diagnosis of 2 cases of cardiomyopathy].

Two cases of cardiomyopathy were studied by echocardiography, endomyocardial biopsy carried out during cardiac catheterization and magnetic resonance imaging. In accordance with echocardiogram, magnetic resonance imaging showed global thickening of the free and septal wall in the first case and apical thickening in the second case. The alteration of the tissue component described by magnetic resonance imaging is in agreement with the histologic description of endomyocardial biopsy. Magnetic resonance imaging is a useful method for the diagnosis of cardiomyopathy.

Biopsy↗