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At least 793 records · Page 44Linked to original sources
PubMed1991

Malignant transformation of aneurysmal bone cyst, with an analysis of the literature.

An 11-year-old girl had a lytic, benign-appearing, expansive lesion of the distal tibia radiologically interpreted as an aneurysmal bone cyst (ABC). Tissue from two extensive curettage procedures was also histologically diagnosed as ABC. Approximately 50 months after the onset of symptoms, and 28 months after her last curettage, a highly pleomorphic osteosarcoma developed. The patient had not received prior radiation therapy. The cases in the literature of possible malignant transformation of ABC are reviewed. The authors separate their case from telangiectatic osteosarcoma, and from "aneurysmal bone cyst-like osteosarcoma."

Bone Cysts↗
PubMed2004

[Simple bone cysts of the calcaneus. Differential diagnosis and therapy].

Fifty-two calcaneal simple bone cysts from our clinic were evaluated. The lesions had a pathognomonic radiologic appearance and diagnosis was histologically confirmed in all operatively treated cases. Four cases presented with pathological fractures, three of which were treated by open reduction internal fixation and bone grafting, while one was treated nonoperatively. In addition, six patients with large cysts without apparent fracture but spontaneous pain were treated by curettage and subsequent autogenous bone grafting or calcium phosphate cement filling, and there were no recurrences. The majority of cysts (42 of 52) were however asymptomatic and thus followed up nonoperatively. This review reports on one of the largest series of cysts in this location. The results indicate that nonoperative management is justified in most asymptomatic cases. However, the potential risk of fracture as indicated by four fractured calcaneal cysts in this series suggests that large cysts should be clinically monitored and that operative intervention is useful in all symptomatic cases to prevent pathologic fractures. In the latter cases, curettage and bone grafting as well as the use of bone substitute material yielded uniformly good results.

Adolescent↗
PubMed1983

An unusual intraosseous lesion with fibroblastic, osteoclastic, osteoblastic, aneurysmal and fibromyxoid elements. "Solid" variant of aneurysmal bone cyst.

Four examples are reported of an unusual noncystic intraosseous lesion which does not conform to any hitherto recognized entity and which can be mistaken, not only by the general histopathologist but by the osteoarticular pathologist, for a variety of other conditions, including sarcoma and giant-cell tumor. They were in patients aged 5 to 13 years; three in the spine, one in the ethmoid. Local excision, supplemented by low-dose radiotherapy in cases with cord compression, produced a satisfactory outcome in all cases. At presentation the radiologic findings were nonspecific but, following treatment, an eggshell rim of bone developed in those lesions which had been incompletely excised. Histologically, they are characterised by florid fibroblastic or fibrohistiocytic proliferation, osteoblastic differentiation with osteoid production, areas rich in osteoclast-type giant cells, aneurysmal sinusoids, and occasional foci of degenerate calcifying fibromyxoid tissue. Because this combination of histologic features can be found in the solid parts of aneurysmal bone cyst and in no other condition, at this centre we have regarded this lesion as a variant of aneurysmal bone cyst devoid of any cystic component.

Adolescent↗
PubMedDate not supplied

Aneurysmal bone cyst of the cervicodorsal spine.

A 23-year-old woman with paraparesis and bladder atonia of one week's duration demonstrated lytic destruction of the anterior elements of C7, D1, and D2, with gibbus deformity at C7. The tumor was excised in August 1975 through an anterior approach and the cervical spine was reconstructed with a five-level, fibular strut bone graft. Several weeks later a posterior fusion was performed. The patient was placed in a halo jacket for three months, at which time solid fusion was achieved. The final pathologic diagnosis was aneurysmal bone cyst. The patient obtained full neurologic recovery after surgery and has had no sequelae or recurrence to date. Involvement of several adjacent cervical vertebrae by an aneurysmal bone cyst is unusual, and a comparable case is rarely reported.

Adult↗
PubMed1994

Aneurysmal bone cyst of the jaws: analysis of 11 cases.

Eleven cases of aneurysmal bone cyst of the mandible treated during a 7-year period were studied. The clinicopathologic features, age distribution, treatment, and surgical results were evaluated and compared with the international literature.

Adolescent↗
PubMed1998

Structural and functional reconstruction after resection of aneurysmal bone cyst of the fifth metatarsal: a case study.

We report a case of a primary benign bone tumor (aneurysmal bone cyst [ABC]) involving the distal portion of the fifth metatarsal, identified in an adolescent. The tumor, histologically identified as an ABC with reparative giant cell reaction, became symptomatic. Treatment included resection, followed by reconstruction of the fifth metatarsal using grafts of autologous bone with preservation of function in the metatarsophalangeal joint. The basis for selecting this form of treatment is discussed, as well as the natural history of ABC and giant cell reparative granuloma. Restoration of form and function is illustrated by this case study with a 23-month follow-up.

Adult↗
PubMed2003

[Aneurysmal bone cyst of the spine in children: a 9-year follow-up of 7 cases and review of the literature].

PURPOSE OF THE STUDY: Aneurysmal cyst is an uncommon benign primitive bone tumor generally observed in young subjects, in a spinal localization in 10% of the cases. We report the clinical, radiological, and therapeutic aspects of seven cases of aneurysmal cyst of the spine. MATERIAL AND METHODS: This series included seven children, mean age 11.7 years (range 8-14) who were followed for 9 years on the average (range 2-24 years). Findings were compared with reports in the literature. RESULTS: Four cysts were located in the cervical spine (C1, C3, C4, C7), two in the thoracic spine (T4, T7) and one in the sacrum. Biopsy-resection was performed in six patients. The sacral cyst was treated by selective arterial embolization. Two complications were observed after surgical treatment. Bony filling of the lesion, evaluated by CT scan six months after surgery, was achieved in five cases, incomplete in two without recurrence of cystic cavities. DISCUSSION AND CONCLUSION: Aneurysmal bone cysts account for 15% of all primitive tumors of the spine. They are more frequent in the cervical and thoracic spine than in a lumbar or sacral localization. One vertebra is involved in most cases, generally the vertebral body and the posterior arch with an asymmetrical extension to one pedicle in some cases. Neurological complications of variable severity are frequent and can be improved by surgical removal of the tumor. CT scan and MRI are the best exams to analyze the spinal cyst, to show bony walls and liquid-liquid levels suggestive of aneurysmal bone cyst, to evaluate the tumor extension and to search for cord compression. When the CT scan and MRI show characteristic signs of aneurysmal bone cyst of the spine, we do not perform a biopsy systematically if complete removal of the tumor appears possible. Surgical removal with biopsy is the treatment of choice. Reconstruction and stabilization of the spine must be complete using bone graft with or without instrumentation. In case of medullary involvement, decompression must be performed rapidly with the most complete tumor removal as possible. Selective arterial embolization can be used in some localizations or as preparation to surgery. Radiotherapy is contraindicated in children because of the risk of radio-induced tumors.

Adolescent↗
PubMed2000

Clinical management of traumatic bone cyst in children: a case report.

A case report of a traumatic bone cyst occurring in a 10-year-old girl which persisted after endodontic treatment of the teeth involved in lesion is presented. The importance of established clinical and radiographic diagnosis in order to avoid radical surgery or unnecessary endodontic treatment in children is discussed.

Bone Cysts↗
PubMed2006

Vertebra plana due to an aneurysmal bone cyst of the lumbar spine. Case report and review of the literature.

Aneurysmal bone cysts (ABCs) are benign, highly vascular osseous lesions characterized by cystic, blood-filled spaces surrounded by thin perimeters of expanded bone. Children and young adults are most often affected by spinal ABCs; more than 75% of patients are younger than 20 years old at presentation. Although ABCs have been documented in all areas of the axial and appendicular skeleton, ABCs of the spine present unique challenges due to the risk of vertebral destabilization, pathological fracture and vertebral body (VB) collapse, and neurological compromise. The authors describe the case of an 8-year-old child who presented with low-back pain and was subsequently found to have a lumbar ABC causing vertebra plana of the L-3 VB. They also review the literature on ABCs of the spine. This case highlights the importance of considering an ABC in the differential diagnosis when vertebra plana is seen in pediatric patients.

Bone Cysts, Aneurysmal↗
PubMed1993

Polyostotic coexisting fibrous dysplasia and aneurysmal bone cyst of the chest wall.

A case of a 39-year-old woman with a palpable mass in the right hemithorax is presented. The mass had been growing during the last 16 years. Radiographs and computed tomography showed two lesions in the right thoracic wall: the greater was in the anterior and lateral portion of the 7th rib, the minor lesion in the 6th rib costovertebral joint. Both lesions were surgically removed. Histological examination demonstrated the association of fibrous dysplasia and aneurysmal bone cyst in the two lesions. The coexistence of these two lesions supports the theory that aneurysmal bone cyst may represent a secondary change due to haemodynamic alterations of the vascular bed caused by fibrous dysplasia.

Adult↗
PubMed1985

Aneurysmal bone cysts of the spine. Report of 17 cases.

Seventeen cases of aneurysmal bone cyst of the spine are reported. Clinical manifestations, methods of investigation, differential diagnosis, treatment, and pathogenesis are discussed. The condition is essentially a benign lesion, affects a young age group, and grows rapidly, often producing a paravertebral mass. Occasionally it becomes acutely exacerbated, causing irreversible damage to the spinal cord. For these reasons, prompt diagnosis and timely treatment are important. Excision of the lesion is the treatment of choice but, if not feasible, thorough curettage and radiotherapy not exceeding 2000 rads are indicated. With a two-stage operation, excision of the lesion is often possible, and the stability of the vertebral column is assured with bone-graft fusions.

Adolescent↗
PubMedDate not supplied

Aneurysmal bone cysts of the jaws: CT and MR findings.

Two cases of aneurysmal bone cyst of the jaws, one in the mandible and the other in the maxilla, are reported in young girls 7 and 15 years old. One was a primary lesion; the other was associated with fibrous dysplasia. In both cases CT and MR demonstrated characteristic fluid-fluid levels. The diagnosis was confirmed after biopsy and surgical resection of the lesions.

Adolescent↗
PubMed1997

Metachronous multiple aneurysmal bone cysts.

We report on a 9-year-old boy with metachronous aneurysmal bone cysts involving the tibia and pubis respectively. The patient has been clinically and radiographically followed for 3 years.

Biopsy↗
PubMed1989

[Solitary bone cyst in childhood: form of presentation and course in 13 cases].

The authors describe 13 cases of solitary bone cyst in children of both sexes, ages 4 5/12 to 12 4/12 years. Ten patients were males. In eight cases the lesions were located in the humerus, three in the femur, one in the tibia and another in the phalanx of the foot. Pathological fracture was the most frequent initial symptom. The characteristic radiological image of the cyst allows the distinction of other bone lesions and is usually enough for the diagnosis. In 8 cases treatment consisted of intracystic injections of methylprednisolone acetate. In three cases relapse was observed.

Anti-Inflammatory Agents↗
PubMedDate not supplied

Aneurysmal bone cyst of the cricoid cartilage: an unusual cause of subglottic stenosis.

Aneurysmal bone cysts (ABC) are locally aggressive bony tumors which rarely occur in the head and neck. Only 3 cases have been reported in the larynx previously, 1 involving the cricoid cartilage. A patient is presented who developed subglottic stenosis with airway compromise due to an ABC arising from the cricoid cartilage. The literature on bony tumors of the laryngeal cartilages was reviewed and the clinical and pathologic findings in this case highlighted.

Adult↗