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At least 793 records · Page 44Linked to original sources
PubMed1979

[How much of classical topical therapy is still current today? (author's transl)].

Classical topical therapy has been largely displaced by the development of up-to-date drugs and advances in the galenic field. Serious objections have even been leveled against some older drugs and others are no longer current in spite of their good efficacy (e.g. dyes) because less discriminatory drugs can be substituted for them. The fundamental principles of classical topical therapy are still as valid as ever (inherent action of the base). However, many of the active principles of the prechemotherapeutic era have meanwhile been superseded as for example boric acid, mercury, desquamative pastes, sulfur among others. In contrast to this, topical applications such as dithranol, salicylic acid, coal tar and a few others still belong to the permanent stock of dermatological topical therapy.

Administration, Topical↗
PubMed1972

[Not Available].

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Balsams↗
PubMed1972

[Not Available].

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Balsams↗
PubMed2004

Head injury and associated maxillofacial injuries.

AIMS: To review patients admitted with head injuries under a regional neurosurgical service, to document the incidence and features of associated maxillofacial trauma, and to assess any delay in referral to a maxillofacial surgeon for definitive management of facial injuries. METHODS: The details of all patients admitted under the neurosurgical service at Christchurch Hospital over the preceding 7 years (1995-2002) were reviewed via that department's database. The records of those patients noted to have a maxillofacial injury were requested, and the following data obtained: demographics, diagnosis, and mode of injury (including specific variables such as alcohol consumption and seatbelt usage in motor vehicle accidents). RESULTS: 2307 patients were admitted under the neurosurgical service at Christchurch Hospital over a 7-year period. Five percent of those patients had an associated maxillofacial injury. Three-quarters were men, with an average age of 27 years. Motor vehicle accidents and assaults were the most common cause of injury. Nearly one-third of those persons in motor vehicle accidents were not wearing seatbelts. Alcohol was more frequently involved in mild and moderate head injuries and these patients were more likely to have been assaulted than those admitted with severe head injuries. There were no significant delays in referring patients admitted who had an associated maxillofacial injury to a maxillofacial surgeon. CONCLUSIONS: A small but significant number of patients admitted with head injuries will have an associated maxillofacial injury.

Adolescent↗
PubMed2004

[Hydatic pulmonary embolism complicating a cardiac hydatic cyst. A case report].

Hydatic pulmonary embolism: complication of a cardiac hydatic cyst:a case report hydatic cardiac cyst is a rare condition and represents only 0.5 to 2% of all visceral localisations of the hydatid disease. We reported a 28 year old patient with a multiple hydatic pulmonary embolism caused by the rupture of a hydatic cyst of the interventricular septum. The diagnosis was established by transthoracic echocardiography and CT Scan. Surgery was performed without delay and the outcome was good after a five month follow-up. This case illustrates the diagnostic value of the non invasive imaging means in hydatic cyst of the heart and underlines the importance of surgery realized before complications occur.

Adult↗
PubMed2005

Cyclosporine lymphocyte maximum level: a new alternative for cyclosporine monitoring in kidney transplantation.

OBJECTIVES: To determine the relationship between clinical outcome, lymphocyte count (LC), and cyclosporine (CsA) lymphocyte maximum level (LT(m)L) in kidney transplant recipients. MATERIALS AND METHODS: CsA LT(m)L was determined in patients with biopsy-proven graft dysfunction and in patients with normal graft function. Clinical outcome was compared according to CsA LT(m)L, dosage, blood trough (C(0)) and maximum (C(max)) levels, hematocrit level, and LC. RESULTS: Rejecting patients had significantly lower LT(m)L than did those with normal graft function (27 -/+ 11 pg/Lc vs 71 -/+ 79 pg/Lc; P < 0.01) and similar LTmL to those with nephrotoxicity (27 -/+ 8 pg/Lc). Patients with normal graft function exhibited significantly lower LC (0.001292 -/+ 696 x 10(9)/L) and serum creatinine levels (88.4 -/+ 35 micromol/L) when compared with rejecting patients (0.001717 -/+ 364 x 10(9)/L, 132.6 -/+ 8.8 micromol/L) and those with nephrotoxicity (0.001884 -/+ 582 x 10(9)/L, 123.7 -/+ 8.8 micromol/L) (P < 0.03, P < 0.001). No significant difference was observed among the 3 groups with regard to CsA dosage, C(0), C(max), mycophenolate mofetil (MMF) dosage, and mycophenolic acid (MPA) plasma levels. CsA LT(m)L closely correlated in an exponential (R(2) = 0.98) and linear (R(2) = 0.35) fashion with LC and hematocrit level, respectively. Conversely, CsA C(max) failed to correlate with C(0) and these 2 latter parameters. Weak correlations were observed between CsA C(max) and its corresponding LT(m)L. CONCLUSIONS: CsA LT(m)L appears to correlate better than CsA C(max) with rejection-free outcome and LC. An increase in hematocrit appears to have an adverse effect on CsA lymphocyte binding. CsA LT(m)L may offer a new alternative for CsA monitoring in kidney transplantation.

Creatinine↗