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A prepubertal and early adolescent bipolar disorder-I phenotype: review of phenomenology and longitudinal course.

OBJECTIVE: Phenomenology, assessment, longitudinal, and psychosocial findings from an ongoing, controlled, prospective study of 93 subjects with a prepubertal and early adolescent bipolar disorder phenotype (PEA-BP) will be reviewed. METHODS: Unlike adult-onset bipolar disorder, for which there were over 50 years of systematic investigations, there were a paucity of rigorous data and much controversy and skepticism about the existence and characteristics of prepubertal-onset mania. With this background, issues to address for investigation of child-onset mania included the following: (i) What to do about the differentiation of mania from attention-deficit hyperactivity disorder (ADHD). (ii) How to deal with the ubiquity of irritability as a presenting symptom in multiple child psychiatry disorders. (iii) Development of a research instrument to assess prepubertal manifestations of adult mania (i.e. children do not 'max out' credit cards or have four marriages). (iv) How to distinguish normal childhood happiness and expansiveness from pathologically impairing elated mood and grandiosity. RESULTS: To address these issues, a PEA-BP phenotype was defined as DSM-IV mania with elated mood and/or grandiosity as one inclusion criterion. This criterion ensured that the diagnosis of mania was not made using only criteria that overlapped with those for ADHD, and that subjects had at least one of the two cardinal symptoms of mania (i.e. elated mood and grandiose behaviors). Subjects were aged 10.9 years (SD = 2.6) and age of onset of the current episode at baseline was 7.3 years (SD = 3.5). Validation of PEA-BP was shown by reliable assessment, 6-month stability, and 1- and 2-year diagnostic longitudinal outcome. PEA-BP resembled the severest form of adult-onset mania by presenting with a chronic, mixed mania, psychotic, continuously (ultradian) cycling picture. CONCLUSION: Counterintuitively, typical 7-year-old children with PEA-BP were more severely ill than typical 27 year olds with adult-onset mania. Moreover, longitudinal data strongly supported differentiation of PEA-BP from ADHD.

Adolescent↗

Impact of analytic conventions on outcome measures in two longitudinal studies of dental caries.

UNLABELLED: Caries increment is the primary outcome measure used in most longitudinal studies of caries. Its computation requires the adoption of specific analytic conventions for handling examiner misclassification ("reversals"), teeth lost due to caries, and multiple events such as caries initiation and progression. However, little is known about the impact of these analytic conventions on cumulative incidence and incidence density--two additional outcome measures used in longitudinal studies. OBJECTIVE: We evaluated the impact of analytic conventions on caries outcome measures in two longitudinal caries studies. METHODS: A secondary analysis was undertaken using data from two studies: a 2-year observational cohort study of 683 older adults and a 3-year clinical trial of 1,754 children. Crude, net and adjusted increments were compared, effects of inclusion and exclusion of teeth lost due to caries were contrasted and measures of caries initiation and progression were assessed among subgroups in each study. RESULTS: Cumulative incidence indicated a high risk of caries (50% or more) in both studies but was not sensitive to subgroup differences. Increment and incidence density measures consistently revealed between-subgroup differences when subgroups had comparable numbers of teeth. For all three outcome measures, crude DFS values were larger than net DFS values. The adjusted DFS was similar to crude DFS in older adults, but similar to net DFS in children. Measurement of caries initiation and progression increased disease estimates for all three outcome measures. CONCLUSIONS: In the populations studied, analytic conventions for handling examiner misclassification, teeth lost due to caries and multiple events had a greater impact on inferences than the choice of outcome measure.

Adolescent↗

Longitudinal study on periodontal conditions in healthy elderly people in Japan.

OBJECTIVES: A strategy for the control of periodontal disease progression is required to prevent tooth loss in older people. However, detailed epidemiological data on periodontal conditions in elderly people is limited. The purpose of the present study is to describe the natural history of periodontal disease and to evaluate the intraoral factors relating to the disease progression in systemically healthy elderly people. METHODS: In the cross-sectional study, 599 and 162 subjects aged 70 and 80 years, respectively, were examined. Of those subjects aged 70 years, 436 (73%) participated in the 2-year longitudinal study. Pocket depth (PD) and attachment level (AL) were measured for all functioning teeth at six sites per tooth. In the cross-sectional study, AL of 4 mm or greater and 7 mm or greater were defined as moderate and severe disease, respectively. In the longitudinal study, a change in AL of 3 mm or greater at each site was defined as periodontal disease progression. RESULTS: In the cross-sectional study, 97.1% of the subjects had at least one site of AL of 4 mm or greater (4+ mm). The prevalence of AL of 7 mm or greater (7+ mm) was 47.9%, with 2.8 affected teeth per person in those with AL 7+ mm. These findings reveal that periodontal disease is extremely widespread in the elderly population. However, very few had many teeth with severe periodontal conditions. In the longitudinal study, 75.1% experienced attachment loss of 3 mm or greater (3+ mm) during the 2-year study period. Of those subjects who experienced attachment loss, a mean of 4.7 teeth exhibited attachment loss. Multivariate logistic regression showed that both the highest AL in each tooth at baseline and abutment teeth for removable partial dentures were significantly related to periodontal disease progression as well as tooth loss incidence. CONCLUSIONS: These results suggest that teeth with poor periodontal conditions as well as abutment teeth for removable partial dentures were significant intraoral factors relating to periodontal disease progression as well as tooth loss.

Aged↗

Marital interaction and satisfaction: a longitudinal view.

Two longitudinal studies of marital interaction were conducted using observational coding of couples attempting to resolve a high-conflict issue. We found that a different pattern of results predicts con-current marital satisfaction than predicts change in marital satisfaction over 3 years. Results suggest that some marital interaction patterns, such as disagreement and anger exchanges, which have usually been considered harmful to a marriage, may not be harmful in the long run. These patterns were found to relate to unhappiness and negative interaction at home concurrently, but they were predictive of improvement in marital satisfaction longitudinally. However, three interaction patterns were identified as dysfunctional in terms of longitudinal deterioration: defensiveness (which includes whining), stubborness, and withdrawal from interaction. Hypotheses about gender differences in roles for the maintenance of marital satisfaction are presented.

Adult↗

Measurement invariance in longitudinal clinical research assuming change from development and intervention.

Valid and reliable measures of psychological and behavioral constructs are critical to clinical research, particularly longitudinal treatment research, in which multiple groups are compared over time for possible changes within and between constructs as a result of intervention or development. Structural equation modeling (SEM) analysis is a class of statistical procedures that can be used to test multiple hypotheses about these relationships simultaneously while controlling for measurement error. The procedures have been applied primarily to testing between-construct relationships in nonexperimental studies, with relatively little emphasis on establishing whether measures are sufficiently invariant across groups and across time to permit these tests. This article uses an empirical example of a longitudinal experimental prevention study with two groups to illustrate the use of SEM, first, to systematically test measurement invariance across groups at each wave of measurement, and second, after establishing measurement invariance, to test structural invariance longitudinally.

Adolescent↗

Structural equation modeling with longitudinal data: strategies for examining group differences and reciprocal relationships.

This article describes the use of structural equation modeling with latent variables to examine group differences and test competing models about cause-effect relationships in passive longitudinal designs. This approach is compared with several other statistical methods including analysis of cross-lagged panel correlations, regression analysis, and path analysis. The mechanics and advantages of structural equation modeling are illustrated using an example based on a 3-wave longitudinal study of adolescents' alcohol use. Within this example, the generalizability of the measurement model and structural model are assessed across gender and time, and competing models about the causes and consequences of adolescents' alcohol use are tested. The article concludes with a discussion of some of the strengths and limitations of using structural equation modeling with longitudinal data.

Adolescent↗

Introduction to special section: the role of longitudinal data with child psychopathology and treatment: preliminary comments and issues.

Longitudinal data can play an important role in child psychopathology and treatment. This article introduces a review of some of the research questions that longitudinal designs can answer and how longitudinal studies have been used in evaluating traditional syndromes in child clinical psychology. We then introduce the articles in this special section.

Child Behavior Disorders↗

Diagnosis, assessment, and treatment of externalizing problems in children: the role of longitudinal data.

Prospective longitudinal studies that pertain to the stability, developmental pathways, and long-term outcome for the 2 primary forms of externalizing behavior problems (conduct problems [CP] and hyperactivity [HA]) are described. Treatment outcome studies for CP and HA with at least 1 year of follow-up data are reviewed. The implications of longitudinal research for the diagnosis, assessment, and treatment of externalizing behavior problems in children are discussed. Greater attention must be paid to issues related to comorbidity, developmentally appropriate assessments, and long-term outcome of interventions. Longitudinal-experimental investigations that serve to delineate developmental pathways as well as assess the effects of developmentally sensitive, comprehensive interventions are recommended.

Adolescent↗

Diagnosis, assessment, and treatment of internalizing problems in children: the role of longitudinal data.

This review examines the role of longitudinal data in the diagnosis, assessment, and treatment of internalizing disorders in children and adolescents. On the basis of the limited longitudinal data available, it is suggested that internalizing disorders in children and adolescents are highly prevalent, frequently comorbid with other childhood disorders, and, arguably so, persistent over time. However, it is also noted that a considerable amount of instability characterizes these disorders and that the developmental course is not fully understood at this time. In addition, these disorders are responsive to treatment, at least on a short-term basis. Finally, a plea is made for longitudinal studies that use a developmental perspective in examining internalizing disorders in children and adolescents.

Adolescent↗

Longitudinal consistency of adult personality: self-reported psychological characteristics across 45 years.

The longitudinal consistency of personality characteristics over a period of 45 years is examined. The data are drawn from the Kelly Longitudinal Study, a panel involving an original group of 300 men and 300 women. Measures of emotional disturbance (from the Bell and Bernreuter inventories) during the 1930s and the 1950s had significant correlations in the .25-.40 range with measures of psychiatric symptoms (from the Cornell Medical Index) taken in 1979-1981. Revised inventory scales with content related to neuroticism and social introversion-extraversion had moderate longitudinal consistency across several decades of adult life and demonstrated convergent and discriminant validity. This study demonstrates the utility of personality measurements in predicting significant psychological outcomes over the full interval of the normal adult lifespan.

Adolescent↗

Longitudinal analysis of specific domains of internal control and depressive symptoms in patients with recurrent cancer.

The relation between perceptions of control and depressive symptoms was examined in a longitudinal study of patients with recurrent cancer. Five domains of control (self-blame, control over cancer onset, control over symptoms, control over the course of the illness, and overall control over life events) were found to be independent of one another. In cross-sectional analyses, depression symptomatology was negatively correlated with illness course control, symptom control, and overall control. Cross-lagged longitudinal analyses using structural equation modeling suggested only onset control and overall control were significantly associated with depressive symptomatology over the 8-month interval. Greater baseline onset control predicted greater follow-up depression, whereas higher baseline depression predicted lower follow-up overall control. The importance of developing and using domain-specific measures of control and investigating the association of control and adjustment in longitudinal analysis are discussed.

Adult↗

Psychological predictors of good health in three longitudinal samples of educated midlife women.

Concurrent and longitudinal associations between cognitive and affective personality variables--intellectual efficiency (IE), anxiety, and hostility--and observer ratings of physical health were examined in 3 longitudinal samples of women: Mills Longitudinal Study (n = 101); Radcliffe Study (RS, n = 118); and University of California, San Francisco Study (n = 44). Observer ratings of health were based on participants' reports of health problems. The California Psychological Inventory (H. G. Gough, 1996) IE, Hostility, and Anxiety Scales were used in all studies at Times 1 and 2, except in RS, when at Time 1 the Zung Anxiety (W. K. Zung, 1971) and the Profile of Mood States (D. M. McNair, M. Lorr, & L. F. Droppleman, 1971) Hostility Scales were used. In the majority of analyses, IE was positively associated with good health, and Anxiety and Hostility were negatively associated with health. IE was the strongest independent predictor of health, indicating that cognitive characteristics may have an important role in health and should be examined further.

Adult↗

A longitudinal study of blood pressure in relation to performance on the Wechsler Adult Intelligence Scale.

A growth curve analysis was used to examine estimated longitudinal decline (over 19 years) on the Wechsler Adult Intelligence Scale (WAIS; D. Wechsler, 1955) in relation to arterial hypertension and blood pressure (BP) for 55 men and 85 women (40 to 70 years old) who were free from overt major coexisting diseases. BP was associated with longitudinal decline for Visualization-Performance (VP) ability and Speed. Hypertension was a weaker predictor of VP and was unrelated to Speed. Age effects on VP were overestimated when averaged BP level, particularly systolic BP, was not controlled statistically. It was concluded that initial BP level and hypertension predict age-related longitudinal decline in specific major abilities assessed by the WAIS but that BP averaged over examinations is a stronger predictor.

Adult↗

Stability and change in adult intelligence: 2. Simultaneous analysis of longitudinal means and covariance structures.

We analyzed data on psychometric intelligence from the Seattle Longitudinal Study, simultaneously estimating longitudinal factors, their covariance structure, and their mean levels. Data on five Thurstone Primary Mental Abilities subtests were available for 412 adults, ages 22-70 at first test, who were tested three times at 7-year intervals. A previous longitudinal factor analysis had shown high stability of individual differences (covariance stability) in general intelligence for three adult age groups. We extended that model to estimate factor means. All three age groups showed high levels of covariance stability, but differed sharply in their mean profiles. The young group showed increasing levels of general intelligence, the middle-aged group had stable levels of intelligence, and the old group showed salient, approximately linear, decline. The patterns of stability in middle-age, followed by mean decline and high covariance stability in old age, suggest a normative developmental transition from a stability pattern to a decline pattern of general intelligence, with the inflection point occurring somewhere around age 60.

Adult↗

Curiosity and stimulation seeking across the adult life span: cross-sectional and 6- to 8-year longitudinal findings.

Giambra (1977-1978, 1979-1980) found that 2 scales of the Imaginal Processes Inventory measuring curiosity (i.e., information seeking) did not change across the adult life span, but 2 measuring stimulation seeking (i.e., boredom) for external stimulation need significantly decreased with age. In this study, these outcomes were replicated (1,356 men and 1,080 women 17 to 92 years old). In addition, a 6- to 8-year longitudinal repeat was obtained on 222 men and 124 women. Significant longitudinal declines were obtained for the stimulation-seeking measures. Furthermore, women showed an increase in impersonal-mechanical curiosity and a decline in interpersonal curiosity, though the amount of change was modest. Men were unchanged on both curiosity measures. Gender differences in longitudinal changes apparently reflected effects of socialization as well as tendencies toward displaying increased androgyny with advancing age.

Adolescent↗

Testing mediational models with longitudinal data: questions and tips in the use of structural equation modeling.

R. M. Baron and D. A. Kenny (1986; see record 1987-13085-001) provided clarion conceptual and methodological guidelines for testing mediational models with cross-sectional data. Graduating from cross-sectional to longitudinal designs enables researchers to make more rigorous inferences about the causal relations implied by such models. In this transition, misconceptions and erroneous assumptions are the norm. First, we describe some of the questions that arise (and misconceptions that sometimes emerge) in longitudinal tests of mediational models. We also provide a collection of tips for structural equation modeling (SEM) of mediational processes. Finally, we suggest a series of 5 steps when using SEM to test mediational processes in longitudinal designs: testing the measurement model, testing for added components, testing for omitted paths, testing the stationarity assumption, and estimating the mediational effects.

Cross-Sectional Studies↗

The longitudinal course of marital quality and stability: a review of theory, method, and research.

Although much has been learned from cross-sectional research on marriage, an understanding of how marriages develop, succeed, and fail is best achieved with longitudinal data. In view of growing interest in longitudinal research on marriage, the authors reviewed and evaluated the literature on how the quality and stability of marriages change over time. First, prevailing theoretical perspectives are examined for their ability to explain change in marital quality and stability. Second, the methods and findings of 115 longitudinal studies--representing over 45,000 marriages--are summarized and evaluated, yielding specific suggestions for improving this research, Finally, a model is outlined that integrates the strengths of previous theories of marriage, accounts for established findings, and indicates new directions for research on how marriages change.

Adult↗

Parental attachment, parental control, and early development of alcohol use: a longitudinal study.

The authors explored the predictive influence of both parental attachment and parental control on early onset of alcohol consumption in adolescence by use of a longitudinal sample of 1,012 young adolescents. Whether the relationship between parental control and adolescents' drinking is moderated by parental attachment was also examined. Consistent with other studies, attachment and strict control were cross-sectionally related to adolescents' alcohol use at all 3 measurements. However, the longitudinal results of structural equation modeling analyses suggest that a good attachment relationship between parent and child does not prevent adolescents from drinking. In addition, strict control was related to lower engagement in alcohol use. Furthermore, with regard to the moderating effect, parental attachment did not moderate longitudinally the association between parental control and an early development of alcohol use. Implications for further research are discussed.

Adolescent↗