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Sterilization processes. Meeting the demands of today's health care technology.

Universal Precautions dictate sterilization for all invasive equipment that break the blood barrier; however, current methods of sterilization, such as steam and ethylene oxide gas (ETO), are not compatible with many of the delicate, heat-sensitive surgical instruments used in modern health care. In addition, traditional sterilization methods are often too time consuming for practical use in the operating room. Clearly, new sterilization processes need to be developed. In this article, the criteria modern sterilization processes must meet and how some manufacturers plan to meet this challenge are discussed. In addition, the pros and cons of using peracetic acid (the newest sterilization process currently available) are examined.

Equipment Contamination↗

Bollen's jig and anterior cruciate ligament reconstruction.

We report the design of a surgical instrument that facilitates the harvest of the autologous patellar tendon in anterior cruciate ligament (ACL) reconstruction. The advantage of this jig is that it is a simple, self-centring device resulting in a reproducible and consistent autograft. Its use also minimises the potential risks of donor site morbidity such as patellar fracture and tendon rupture. We briefly describe our technique and discuss its advantages.

Anterior Cruciate Ligament↗

Sharp object injuries in the hospital: causes and strategies for prevention.

We identified characteristics of items causing sharp object injuries in hospital personnel during a 10-month interval. Sharp objects were defined as items that were not hollow-bore needles, that cause lacerations or puncture wounds. Workers reporting sharp object injuries were interviewed to determine what items caused injury and the circumstances of their injuries. Of 89 incidents, 51% were surgical instrument injuries, 19% were lancet injuries, 16% were glass injuries, and 15% were caused by other sharp items. A frequent feature of sharp objects causing injuries was the necessity of disengaging a disposable sharp item from a reusable holder. The application of manual force to fragile glass items also caused many injuries. Opportunities for safer product design and improved materials are discussed to reduce this common occupational hazard.

Accidents, Occupational↗

Paré as a neurosurgeon.

The Cowlishaw Collection gives a splendid representation of the works of a Ambroise Paré (1510-1590). His Complete Works, in the great French edition edited by J.F. Malgaigne, are essential in any study of Paré's achievement, but the 1649 English edition provides a good basis for consideration of Paré's practice in what would now be termed neurosurgery. Paré had a large clinical experience in head injury management. His patients included Henri II King of France, who died from a penetrating orbital wound, and be described a number of other craniofacial wounds sustained in war or in warlike sports. His surgical instruments and operative techniques do not appear very innovative, but were doubtless good in their day; his methods of trephination compare favourably with those of the English surgeon John Woodall, his younger contemporary. He operated on head injuries and cranial infection, but had no capacity to treat intradural conditions, such as cerebral abscesses and tumours: his technical limitations are obvious, and the physicians on whom he had to rely could give him no guidance in neurological diagnosis. He was keenly interested in developmental malformations, and described several conditions that would now be referred to a paediatric neurosurgeon. Paré is of great historical importance as an outstanding Renaissance surgeon, whose influence extended throughout the literate world, and as far as Japan. With him, France replaced Italy and Spain in leadership in European surgical progress, a position that France retained at least until the age of Hunter.

Craniotomy↗

Use of an intuitive telemanipulator system for remote trauma surgery: an experimental study.

BACKGROUND: Death from battlefield trauma occurs rapidly. Potentially salvageable casualties generally exsanguinate from truncal hemorrhage before operative intervention is possible. An intuitive telemanipulator system that would allow distant surgeons to remotely treat injured patients could improve the outcome from severe injuries. STUDY DESIGN: We evaluated a prototype, four-degree-of-freedom, telesurgery system that provides a surgeon with a stereoscopic video display of a remote operative field. Using dexterous robotic manipulators, surgical instruments at the remote site can be precisely controlled, enabling operative procedures to be performed remotely. Surgeons (n = 3) used the telesurgery system to perform organ excision, hemorrhage control, suturing, and knot tying on anesthetized swine. The ability to complete tasks, times required, technical quality, and subjective impressions were recorded. RESULTS: Surgeons using the telesurgery system were able to close gastrotomies remotely, although times required were 2.7 times as long as those performed by conventional techniques (451 +/- 83 versus 1,235 +/- 165 seconds, p < 0.002). Cholecystectomies, hemorrhage control from liver lacerations, and enterotomy closures were successfully completed in all attempts. Force feedback and stereoscopic video display were important for achieving intuitive performance with the telesurgery system, although tasks were completed adequately in the absence of these sensory cues. CONCLUSIONS: We demonstrated the feasibility of performing standard surgical procedures remotely, with the operating surgeon linked to the distant field only by electronic cabling. Complex manipulations were possible, although the times required were much longer. The capabilities of the system used would not support resuscitative surgery. Telesurgery is unlikely to play a role in early trauma management, but may be a unique research tool for acquiring basic knowledge of operative surgery.

Abdominal Injuries↗

Microstructure technologies and their potential in medical applications.

One of the major fields of application of microstructure technology and microsystems technology will probably be centered in medical engineering. Above all in neurosurgery, highly sophisticated surgical instruments featuring high functionality combined with high reliability are needed. Products fabricated by conventional manufacturing technologies can fulfill these demanding requirements only to a limited extend. At the Karlsruhe Nuclear Research Center first prototype components such as microspectrometers, microturbines and microfluidics structures are presently fabricated and tested which can be used in future microendoscopes as sensors or actuators. Combined with adequate information processing and suitable interface technology, it will be possible to create microsystems for various medical applications.

Biomedical Engineering↗

[An ancient surgical set in the history of medicine museum at the medical history and ethics department at Cerrahpaşa Medical School].

The present head of the Department of Medical History and Ethics, Prof. Dr. Nil Sari founded a museum for the history of medicine within the Department. A set of surgical instruments, granted by Prof. Dr. M. Kemal Oke and Prof. Dr. Fuat Kâmil Berksan to the Department, is studied in this article. The set, all made of bronze, and dating approximately back to the IVth century B.C. consists of four bistouries, two pincets, two bone catheters, a cauterization instrument, a spatula, curettage instrument and an unidentified piece. They do not have any trace of corrosion. No sign, badge or stamp can be detected on the instruments. Apparently they have not been used much. The skilfull handicraft, harmonious and excellent style of the set suggest that they might have been produced by an artist or in accordance with the description of a master surgeon. Presence of a pincet for eye surgery suggests that the owner might have been an ophtalmologist. Since the granters had not given any clue of the site they were discovered, it is hard to determine where or by whom the set was made.

Equipment and Supplies↗

Endoscopic endonasal approach to the ventral cranio-cervical junction: anatomical study.

OBJECTIVE: In order to develop an endoscopic endonasal approach to the ventral cranio-cervical junction and odontoid process under the concept of a minimally invasive surgical strategy, a cadaver study was performed. METHODS: Sixteen artery-injected adult head specimens were used. Endonasal endoscopic approach was made through one- or two-nostril routes following the Jho's endonasal paraseptal technique. Rod-lens endoscopes, which were 2.7 or 4 mm in diameter, 18 cm in length with 0-, 30-, and 70-degree lenses, were used. RESULTS: Surgical landmarks leading to the craniocervical junction were the inferior margin of the middle turbinate, nasopharynx and Eustachian tube. The nasopharynx was readily identified following the inferior margin of the middle turbinate. The line drawn between the Eustachian tubes indicated the juncture between the clivus and atlas. With a midline mucosal incision, the ventral cranio-cervical junction was exposed. Odontoid resection was performed with removal of the anterior arch of the atlas. Clival resection can be performed as much rostral as required. Maneuverability of the surgical instruments was better with a two-nostril technique than with a one-nostril. Although the entire midline clivus was accessible rostrally, C-2 was the caudal limit through this endonasal route. A suturing device needed to be developed for mucosal or dural closure for live operations. CONCLUSION: This cadaver study demonstrates that an endoscopic endonasal approach to the ventral cranio-cervical junction and odontoid process can be a valid alternative to the conventional transoral approach.

Cranial Fossa, Posterior↗

Laparoscopic-assisted extracorporeal ovarian cystectomy: a new technique.

An increasing number of adnexal masses are currently managed laparoscopically, which has hampered progress regarding the different techniques of laparoscopic surgery. In this chapter, a modified application of surgical instrument was described in laparoscopic ovarian cystectomy-we named this device, Lap-Disc Mini. This new instrument has three rings, an inner flexible ring fixed to a middle ring by a rubber corset, and an additional dynamic outer ring that has a rubbery-like iris opening, which allows the application of different-sized trocars and extracorporeal ovarian cystectomy. This technique has proved to be effective and safe, especially in removing large ovarian cyst.

Adult↗

Animal surgery during spaceflight on the Neurolab Shuttle mission.

INTRODUCTION: A surgical procedure has never been required or performed on a human in space. Parabolic microgravity simulations have suggested that surgery would be technically feasible during spaceflight. PROCEDURES: Survival surgery was performed for the first time on rats during the STS-90 Neurolab Shuttle mission. Craniotomy, leg dissection, thoracotomy, laminectomy, and laparotomy were performed as a part of physiological investigations. RESULTS: Surgical techniques successfully demonstrated in rats during spaceflight included general anesthesia, wound closure, wound healing, hemostasis, control of surgical fluids, operator restraint, and control of surgical instruments. No decrement in manual dexterity was noted by the crew, although operative time was longer compared with ground experience due to the need to maintain restraint of surgical supplies and instruments. CONCLUSIONS: The demonstration that technically demanding dissections could be accomplished successfully in space on rats suggests that comparable complex surgical procedures should be feasible on humans, if necessary, on future long-duration missions.

Aerospace Medicine↗

Acute haemorrhagic keratoconjunctivitis following laser in situ keratomileusis.

We report two cases of acute haemorrhagic keratoconjunctivitis which occurred following laser in situ keratomileusis (LASIK) during an ongoing epidemic. Both cases underwent preoperative investigation and surgery on the same day. The possible sources of contamination include the paramedical staff, the contact instruments used for performing preoperative investigation, surgeon, nurse, surgical instruments and eye drops. However, the flap was intact with no haze or regression and at 1 year follow up, the visual acuity was maintained at 6/6 in both the patients. We recommend greater caution while performing contact investigations and strict surgical asepsis during LASIK surgery, routinely as well as during epidemics of conjunctivitis.

Acute Disease↗

[Intraoperative navigation in paranasal sinus surgery with the Philips "Neuroguide" system].

OBJECTIVE: To investigate the feasibility, precision and usefulness of computer aided surgery in ENT-sinus surgery. MATERIAL AND METHODS: 5 Patients with chronic sinus pathology and an indication for sinus surgery were elected. For intraoperative navigation we used a Philips "NEUROGUIDE" system and surgical instruments with LED's. Navigation procedures are described in detail in the paper, the system's precision was measured by pointing at anatomical landmarks. The accuracy was measured as the distance in millimeter between the bony structures of the CT scan on screen and the haircross of the pointer's tip on the screen. Another parameter of the systems accuracy was calculated by the system itself as the root mean square error in millimeter (RMSE) between the registered markers position and the marker position in the CT data set. RESULTS: Axial 3/3/1 mm spiral CT provided sufficient resolution, data transfer via optical disk was practicable. Positioning of the navigation equipment required some experience and the registration of the patients head position needed attention, as the markers have to be pointed at precisely. During operation, the head tracking system must not change its position on the patients head to ensure a correct navigation display. The main advantage of the computed navigation system was the constant orientation during the sinus surgical procedure. Frontiers and critical anatomical structures could be identified in the corresponding CT data set, thus enabling the surgeon to decide on the further procedure. At present stage, the operation time was increased through the handling of the navigation system for at about 15 min, resulting in additional time of narcosis. CONCLUSION: We found the computed navigation system Philips "NEUROGUIDE" system to be an established technical aid, ready to use for ENT sinus surgery, in our cases with a precision between 1 and 3 mm. These results were similar to results obtained with a SPOCS Navigation System from Aesculap, as previously published by us [17].

Adult↗

Reduction of head size in advanced hydrocephalus: a case report.

On October 8, 1951, at the dawn of modern neurosurgical treatment of hydrocephalus and other cranial abnormalities, the parents of a child with advanced hydrocephalus posed the question: might the size of the head be reduced so as to allow sitting, standing, and perhaps walking? With the ingenious assistance of the child's father, who devised and made unique surgical instruments, the objectives were accomplished over a period of almost 2 years during which more than a dozen operations were carried out, including one of the first lumbar subarachnoid to peritoneum shunts using the Touhy needle instead of laminectomy. The operations conducted, the devices and tactics used, and the end results are described. No opportunity to treat another patient similarly has presented itself in the over 30-year interval since then, but I believe that the concept is valid and that success is realizable by others who may wish to use some of the techniques described, with appropriate modification.

Cephalometry↗

Effects of dopexamine in a rat model of supracoeliac aortic cross-clamping and declamping.

This experimental study in rats was designed to demonstrate effects of dopexamine (3 microg kg(-1) min(-1), n = 6) or physiologic saline solution (n = 6) on systemic as well as regional perfusion during 30 min of supracoeliac aortic cross-clamping and during 180 min of reperfusion following declamping. Rats were surgically instrumented with arterial, right atrial and portal venous catheters, ultrasonic flow probes around the abdominal aorta, superior mesenteric and carotid artery, and a paediatric tonometer for intestinal mucosal PCO(2) measurement. During 120 min of reperfusion, fluid resuscitation was titrated to keep abdominal aortic blood flow above 80% of baseline values. We found that during cross-clamping, values of arterial lactate (p = 0.002) and intestinal tonometric PCO(2) (p = 0.018) were higher in the dopexamine group than in the control group.

Animals↗

Meniscus surgery using the Watanabe arthroscope.

1. The present uses for arthroscopic meniscus surgery are explained. 2. Postoperative care is facilitated by arthroscopic meniscus surgery. However, improvement in surgical instruments and manipulation is necessary in order to complete the surgery in a short time and to make it easy to perform. 3. Total meniscectomy is especially useful in the Japanese because the discoid meniscus was observed in 16.6 per cent in my arthroscopic study. The incidence is considerably higher than that in foreigners. The procedure for arthroscopic total meniscectomy must be improved. 4. The three puncture method is useful. 5. Partial meniscectomy yields excellent results, but there are pitfalls to watch for. 6. A case of combined surgery with partial meniscectomy and meniscorisis is presented.

Adult↗

A quiet hand for microneurosurgery: twiddle your thumb. Technical note.

Fatigue is both the most tremor-producing factor and the constant companion of a busy neurosurgeon. Because of the difficulty in controlling tremor-generating factors, the authors sought to develop a means of manipulating surgical instruments with minimal muscle movement while allowing accurate and repeatable movements in all conditions. The "quiet hand technique" is an isolation technique that creates a stable platform by forming the four fingers into a salute that thenceforth moves as one. Fine movements are supplied by the thumb. For instruments that open and close, the thumb abducts and adducts. For suture placement using a round needle holder, the thumb flexes and extends. Because only the thumb moves, the extent of movement is decreased and therefore momentum and inertia are limited as well. Previously, microsurgeons favored ballistic movements. With the quiet hand technique, however, tension movements are easy. The greater control makes tying 10-0 and 11-0 sutures more predictable. Although the quiet hand technique was developed for use in small-vessel anastomosis, the neurophysiological principles on which it is based apply to movement at all levels and are applicable to working a bipolar coagulator, pickups, a vascular clip holder, or other soft-tissue manipulators.

Anastomosis, Surgical↗

Medical devices; classification for medical washer and medical washer-disinfector. Final rule.

The Food and Drug Administration (FDA) is classifying the medical washer and medical washer-disinfector intended for general medical purposes to clean and dry surgical instruments, decontaminate or disinfect anesthesia equipment, hollowware, and other medical devices into class II (special controls). FDA is also identifying the guidance document entitled "Class II Special Controls Guidance Document: Medical Washers and Medical Washer-Disinfectors" (the guidance) as the special control that, in addition to general controls, the agency believes will reasonably ensure the safety and effectiveness of the device. This action is being taken under the Federal Food, Drug, and Cosmetic Act (the act), as amended by the Medical Device Amendments of 1976 (the 1976 amendments), the Safe Medical Devices Act of 1990 (the SMDA), and the Food and Drug Administration Modernization Act of 1997 (the FDAMA).

Device Approval↗

[Hygenic measures for Creutzfeldt-Jakob disease].

The Creutzfeldt-Jakob disease (CJD) belongs to the so-called prion diseases or transmissible spongiform encephalopathies. The iatrogenic transmission of the pathogen by direct contact with infectious tissue, tissue extracts and surgical instruments has been demonstrated. CJD is not an infectious disease in the usual sense. Transmission is not possible by normal social contact nor by nursing measures just as CJD can not be transferred by normal skin contact or contact with blood, serum or other patient' secretions. Therefore, CJD patients do not have to be isolated, because strict conformity to the generally recognized rules of hygiene is completely sufficient. The high resistance of prions to environmental influences requires the combination of different disinfection and sterilization measures before inactivation of the pathogen occurs and it is possible to exclude transmission by medical products.

Creutzfeldt-Jakob Syndrome↗