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At least 775 records · Page 43Linked to original sources
PubMed1995

Microvenous thrombosis rates following anastomosis with vein grafting and a knotted suture.

An experimental microvenous thrombosis model was developed combining vein grafting in femoral vein defects with exaggerated vessel injuries using a knotted suture in the vessel repair. The rat femoral vein grafts were separately subjected to injuries caused by an anastomosis performed with a suture knotted with eight half-hitches at the distal anastomosis (upstream), the proximal anastomosis (downstream), and both anastomotic sites. These groups were compared to vein grafting done with a standard suture. Vessel patency was assessed at 20 min and 24 hr, and the thrombus component was histologically analyzed at 24 hr after the procedures. One hundred percent of control vein grafts were patent at 24 hr. All experimental groups had significantly decreased patency at 24 hr (P < 0.001). Among the experimental groups, knotted suture anastomoses at both anastomoses produced significantly lower patency (13.3%, P < 0.05) than knotted suture anastomoses at distal anastomoses. Histological analyses of thrombosed grafts showed that a large amount of thrombocyte deposition and inflammatory cells were noted at both anastomotic sites in the vein grafts with a knotted suture at the distal anastomosis and in the grafts with a knotted suture at both anastomoses. Thrombocyte deposition and inflammatory cells were seen only at the site of proximal anastomosis when using a knotted suture at the proximal anastomosis site alone. This study demonstrated that quantified microvenous thrombosis can be produced by exaggerating vessel injuries with a knotted suture in a vein graft model. This thrombosis model can be used to study the effects of antithrombogenic agents.

Anastomosis, Surgical↗
PubMed1999

Running closure of clean and contaminated abdominal wounds using a synthetic monofilament absorbable looped suture.

The effectiveness of using an absorbable suture material for continuous closure of abdominal wounds, especially contaminated wounds, has not yet been determined. Thus, the present study was conducted to investigate the wound complications that developed following continuous closure of clean and contaminated abdominal wounds using polydioxanone (PDS), compared with those that developed following interrupted closure using braided silk. Running closure using PDS was performed in 152 patients (PDS group), while 280 patients who underwent interrupted closure using braided silk served as controls (SILK group). The occurrence rates of wound dehiscence, early wound infection, and incisional hernia did not differ significantly between the two groups; however, the incidence of late suture sinus formation in the PDS group (1.3%) was significantly lower than that in the SILK group (7.1%). Moreover, late suture sinus formation following PDS suturing healed within 1 week after percutaneous drainage alone without removal of suture strings, whereas late suture sinus following braided silk suturing took an average of 16 days to heal and required removal of the infected suture strings in all 20 patients. These findings indicate the potential usefulness of PDS as a suture material to achieve running closure of clean or contaminated abdominal wounds.

Abdominal Injuries↗
PubMed2004

A prospective randomized trial of hand-sutured versus mechanically stapled anastomoses for gastroduodenostomy after distal gastrectomy.

BACKGROUND: Although mechanical stapling is now an established alternative to conventional hand suturing for the construction of gastrointestinal anastomoses, its role in gastroduodenostomy remains to be defined. We compared the clinical outcome after mechanical stapling with that after hand suturing in patients who underwent gastroduodenostomy after distal gastrectomy. METHODS: From April 2000 through August 2001, a total of 187 patients with gastric cancer who received distal gastrectomy were randomly assigned to reconstruction by mechanically stapled or by hand-sutured gastroduodenal anastomoses. RESULTS: The baseline clinical characteristics were similar in the patients with mechanically stapled and those with hand-sutured anastomoses. There was no in-hospital mortality in either group. One patient (1.1%) in the mechanically stapled group ( n = 92) and 2 (2.1%) in the hand-sutured group ( n = 95) had anastomotic leakage. Anastomotic stenosis developed in 4 patients (4.3%) who underwent mechanical stapling, as compared with 6 (6.3%) who underwent hand suturing. Anastomotic bleeding occurred in 1 patient (1.1%) who under-went mechanical stapling and 1 patient in the hand-sutured group (1.1%). Mechanical stapling of the anastomoses was significantly quicker than hand-suturing of the anastomoses (median time, 14 vs 25 min; p = 0.02). The two groups were comparable with respect to other outcome measures, including incidence of general complications, recovery of gastrointestinal function, duration of postoperative hospital stay, and radiological diameter of the anastomosis. CONCLUSION: In patients with gastric cancer who undergo gastroduodenostomy after distal gastrectomy, mechanical stapling is quicker than hand suturing. These procedures are similar with respect to anastomotic complications and other outcome measures.

Aged↗
PubMed2006

Scleral fixation using suture retrieval through a scleral tunnel.

Scleral fixation of intraocular lenses (IOLs) can be performed under the protection of a scleral flap. A variation of this technique uses a scleral tunnel for suture fixation to the eye. Passage of a double-armed suture through the roof of the scleral tunnel with subsequent retrieval of the suture ends through the external incision for tying facilitates scleral fixation. This modification offers several advantages: A scleral tunnel is easier to construct than a triangular flap and does not require suture closure. It affords a greater surface area for suture placement through an ab externo or ab interno approach. Tying each suture allows the suture knot to pass under the roof of the tunnel, eliminating the need for suture knot rotation. Suture retrieval and scleral fixation through a scleral tunnel incision offers a simplified and elegant method for fixation of IOLs and other intraocular adjunctive devices.

Humans↗
PubMed1992

11-0 mersilene as running suture for penetrating keratoplasty.

We evaluated astigmatic results and complications of the combined suturing technique in penetrating keratoplasty by using 11-0 Mersilene as a running suture. Twenty-seven grafts were studied for a follow-up that ranged between ten and 46 months (mean, 27.2 months). During the study, complications included three graft failures, one instance of inadvertent breakage of the running suture, one instance of one suture bite cutting through the recipient cornea, and suture microabscesses in two eyes. Keratometric astigmatism was 2.5 +/- 2.1 diopters at six months, was 2.4 +/- 2.3 diopters at 12 months, and was 2.5 +/- 2.0 diopters at 24 months. Our data indicate that 11-0 Mersilene is suitable for the running suture in corneal transplants in the combined technique. Spontaneous suture dissolution did not occur throughout the follow-up period. The use of a less biodegradable suture enables the maintenance of low levels of astigmatism for longer periods when compared with a previous study that used 11-0 nylon suture.

Adult↗
PubMed1981

Immobilization of disc heart valves by unraveled sutures.

Disc immobilization by a prolapsed suture end was observed in a laboratory animal with a pivoting disc heart valve. An identical occurrence was experienced in a clinical situation by other investigators. These experiences prompted a review of sutures and suturing techniques in implanting disc heart valves, in an effort to ascertain the vulnerability of all disc valves toward disc immobilization by sutures. An attempt was made to immobilize the discs in five currently available heart disc valves with prolapsed sutures under various handling conditions. Variables included the model of disc valve, the location of the prolapsed suture, and the type of suture material used. Our investigation showed that any of the valves studied can be immobilized by prolapsed sutures. However, this complication is avoidable if the implanting surgeon adheres to a few precautionary suturing principles.

Animals↗
PubMed1995

Subcuticular sutures and the rate of inflammation in noncontaminated wounds.

STUDY OBJECTIVE: To determine whether buried, absorbable, subcuticular sutures increase the degree of inflammation in noncontaminated wounds. DESIGN: Randomized, blinded, prospective trial. SETTING: Laboratory. PARTICIPANTS: Eleven Sprague-Dawley rats weighing 300 to 325 g. INTERVENTIONS: Four wounds were made on each rat. Two wounds on each were closed with three interrupted buried, absorbable, subcuticular sutures 6-0 polyglactin 910 and running 5-0 nylon skin sutures. The other two wounds were closed with running 5-0 nylon skin sutures alone. RESULTS: Fourteen days after the sutures were placed, the animals were killed, and histologic preparations were made from each wound. Each sample was scored on a scale of 0 to 3 for the presence of inflammatory infiltrates, fibroplasia and capillary proliferation, necrosis, exudates, giant cells, and edema. We determined a total wound score by adding the scores from each category. The mean total wound score was 4.46 +/- 2.92 for those closed with buried, absorbable, subcuticular sutures and 4.91 +/- 2.56 for those closed without buried, absorbable, subcuticular sutures. Using the Wilcoxon rank-sum test, we found no statistically significant difference in mean total wound score of wounds closed with and without buried, absorbable, subcuticular sutures (alpha = .01). The probability of detecting a twofold difference in total wound scores was 60% (beta = .40). CONCLUSION: Buried, absorbable, subcuticular sutures do not significantly increase the degree of inflammation in noncontaminated wounds.

Animals↗
PubMedDate not supplied

Mode of failure for rotator cuff repair with suture anchors identified at revision surgery.

Rotator cuff tears are a common cause of shoulder pain and dysfunction. After surgical repair, there is a significant re-tear rate (25%-90%). The aim of this study was to determine the primary mode of mechanical failure for rotator cuffs repaired with suture anchors at the time of revision rotator cuff repair. We prospectively followed 342 consecutive torn rotator cuffs, repaired by a single surgeon using suture anchors and a mattress-suturing configuration. Of those shoulders, 21 (6%) subsequently underwent a revision rotator cuff repair by the original surgeon, and 1 underwent a second revision repair. Intraoperative findings, including the mode of failure, were systematically recorded at revision surgery and compared with the findings at the primary repair. In addition, 81 primary rotator cuff repairs had a radiographic and fluoroscopic evaluation at a mean of 37 weeks after repair to assess for any loosening or migration of the anchors. At revision rotator cuff repair, the predominant mode of failure was tendon pulling through sutures (19/22 shoulders) (P <.001). Two recurrent tears occurred in a new location adjacent to the previous repair, and one anchor was found loose in the supraspinatus tendon. The mean size of the rotator cuff tear was larger at the revision surgery (P =.043), the tendon quality ranked poorer (P =.013), and the tendon mobility decreased (P =.002), as compared with the index procedure. The radiographs and fluoroscopic examination showed that all 335 anchors in 81 patients were in bone. Rotator cuff repairs with suture anchors that underwent revision surgery failed mechanically by three mechanisms, the most common of which was tendon pulling through sutures. This suggests that the weak link in rotator cuff repairs with suture anchors and horizontal mattress sutures, as determined at revision surgery, is the tendon-suture interface.

Adult↗
PubMed2000

Conventional running suture and continuous double loop closure: an experimental study of wound strength.

OBJECTIVE: To study the strength of laparotomy wounds closed by a continuous double loop technique or a conventional running suture, taking into account the ratio of suture length: wound length. DESIGN: Experimental study. ANIMALS: 60 Sprague-Dawley rats. INTERVENTIONS: Midline laparotomy incisions were closed with either a conventional running suture or a continuous double loop. Wounds were allocated to closure with a suture length: wound length ratio of 3, 4 and 7. MAIN OUTCOME MEASURES: Bursting pressure, bursting volume and the way the suture cut through the tissues. RESULTS: With a suture length: wound length ratio of 3 or 4 bursting pressure and bursting volume were lower with a continuous double loop closure. A conventional running suture and a continuous double loop produced similar bursting pressure and bursting volume only if closure was with a ratio of 7. CONCLUSIONS: Wound bursting strength is higher with a conventional running suture than with a continuous double loop closure when the effect of the suture length: wound length ratio is accounted for.

Animals↗
PubMed1997

The "round block" purse-string suture: a simple method to close skin defects with minimal scarring.

We report the use of a subcuticular purse-string suture for closure of surgical skin defects, a simple maneuver that we have found to be very useful in closing difficult wounds and reducing scarring. The purse-string suture is performed with a large nonabsorbable suture that is passed intradermally and left in situ at least 4 weeks. This technique has been applied in 196 patients for a total of 221 sutures over a period of 2 years, being used to close skin defects from 2 x 2 to 8 x 11 cm in many areas of the body. All the patients showed, at closure, a large number of concentric redundant folds as well as considerable distortion of nearby structures; both improved impressively over a period of 2 to 3 weeks and became nearly normal at the time of suture removal (4 to 8.2 weeks, mean 5.7 weeks). The initially very limited and almost circular scar oriented itself along the skin tension lines over a period of a few weeks and, when matured, was always shorter than the original defect. In general, minimal scar widening occurred when we used larger sutures (more than 0-1) that were left longer (more than 6 weeks). Complications have been 23 cases of dehiscence (10.4 percent) in 23 patients (between the fifth and sixteenth days, mean 6.7 days); they were caused by the bad quality of the skin and by the use of too small sutures that cut through the dermis. The "round block" suture has many advantages: 1. It is a simple, inexpensive, and rapid technique for closing wounds by expanding the surrounding skin and often avoiding the use of skin grafts and/or local flaps. 2. It can minimize scarring; the final scars are shorter than the original defect and usually of very good quality. 3. It allows a very useful temporary closure that stretches the surrounding skin while waiting for the definitive histologic report. If this method is not chosen as a definitive closure, later repair with local flaps may be facilitated. 4. For the reasons expressed above, it never compromises the final result even in cases of dehiscence. The main disadvantage is the acceptability of the method on the part of patients, who need to be carefully prepared for both the gross initial distortion and the long time the suture has to be retained; nevertheless, patient satisfaction with the final results in generally very high, especially in large excisions of the face.

Adolescent↗
PubMed1998

Postoperative suture manipulation for control of corneal graft astigmatism.

PURPOSE: To assess the effect on post-keratoplasty astigmatism of postoperative manipulation of a single running suture. METHODS: All corneal transplant patients in whom a single 10/0 nylon running suture was placed between November 1990 and April 1996 were included in a prospective study of the effect of manipulation of the suture at the earliest possible time after surgery when the keratometry became possible by virtue of the epithelial surface integrity and where this revealed astigmatism of greater than 2 D. RESULTS: One hundred and ninety eyes underwent suture manipulation and were followed up. Follow up on 30 eyes was discontinued. Repeat manipulation of the running suture was the most common reason for discontinuation of follow up. The remaining patients were followed for a mean (+/- SD) 415.5+/-326.4 days. Mean astigmatism of 7.8+/-3.1 D was reduced to 1.7+/-2.0 D immediately after manipulation, but regressed to 3.0+/-1.9 D (n = 76) by 1 year. The suture was removed in 32 patients. Twenty-five eyes had post-removal astigmatism measurements. In these 25 eyes, astigmatic error appeared not to revert to premanipulation levels. The only significant complication was one broken suture at manipulation. CONCLUSIONS: Early suture manipulation is effective in reducing suture in post-keratoplasty astigmatism, but some regression is seen.

Astigmatism↗
PubMedDate not supplied

Circumferential suture of the mitral annulus for correction of mitral regurgitation in dogs.

OBJECTIVE: To develop a method for reducing mitral regurgitation in dogs by positioning and tightening a circumferential suture around the mitral valve annulus. STUDY DESIGN: Description of clinical cases. ANIMALS: 15 dogs with spontaneous mitral valve disease, annular dilation, and refractory congestive heart failure treated between 1962 and 1994. METHODS: A composite suture material was constructed using braided Teflon-impregnated polyester sternotomy suture, barium sulfate thread, and Silastic tubing. Through a left lateral thoracotomy, the suture was positioned around the mitral annulus by passing it through the coronary sinus, right atrium, and underneath the left coronary arteries before tightening it. RESULTS: Six dogs died during surgery because of hemorrhage from the left atrium, coronary sinus, or left coronary artery. Three dogs died postoperatively because of coronary artery compression by the suture. Satisfactory suture placement was achieved in six dogs, three of which were long-term survivors (6 to 26 months) before they were euthanatized for noncardiac reasons. CONCLUSIONS: Reduction of mitral annulus diameter with a circumferential purse-string suture does not require cardiopulmonary bypass. The surgery is technically difficult, and detailed knowledge of coronary artery anatomy is required. The current suture design is inexpensive, radiopaque, and biocompatible; no special instruments are required for placement. CLINICAL RELEVANCE: Mitral regurgitation is the most common cardiovascular disorder in dogs and the most common cause of congestive heart failure. Annular dilation occurs as a consequence of mitral regurgitation. Placement and tightening of a circumferential suture around the mitral annulus reduces the degree of mitral regurgitation.

Animals↗
PubMed2006

Suturing a tear of the anterior capsulorhexis.

AIM: To describe a new technique of suturing a tear in the anterior capsulorhexis. METHODS: Continuous curvilinear capsulorhexis (CCC) with lens removal was done in five fresh cadaver eyes. The diameter of the CCC was measured with a calliper. Using the same calliper a tear of the CCC was created while opening the calliper's arms. The distance between the calliper's arms needed to tear the CCC was documented. Using 9-0 Ethilon 9011, CS 160-6 sutures in two eyes, 9-0 Prolene, D-8229, CTC-6L sutures in two eyes, and 10-0 Prolene, 9090, CTC-6 suture in one eye, the tears were sutured. A tear in the CCC was created again in the same way as the first tear. The distance between the calliper's arms needed to tear the CCC was documented again. RESULTS: Suturing of the tear restored some of the strength/elasticity of the CCC. Better results were found while using the 9-0 Prolene, D-8229, CTC-6L sutures than with the two others sutures. CONCLUSIONS: Suturing of a broken CCC can restore at least some of the strength/elasticity of the CCC. This can be important before intraocular lens (IOL) implantation for the safety of the implantation or after the implantation to ensure proper fixation of the IOL.

Biomechanical Phenomena↗
PubMed2005

Biomechanical evaluation of meniscal repair systems: a comparison of the Meniscal Viper Repair System, the vertical mattress FasT-Fix Device, and vertical mattress ethibond sutures.

BACKGROUND: The biomechanical characteristics of the Meniscal Viper Repair System have not been previously studied. HYPOTHESIS: Comparable meniscal lesion fixation standards will exist among the Meniscal Viper Repair System, the vertical FasT-Fix device, and vertical mattress sutures. STUDY DESIGN: Controlled laboratory study. METHODS: Porcine menisci (3 groups of 7 menisci each) were repaired using different devices. A servohydraulic device cycled each construct between 5 N and 50 N for 500 cycles before load to failure (5 mm/min). Group differences were evaluated with 1-way analysis of variance and Tukey post hoc tests. RESULTS: During cyclic testing, the vertical mattress suture group (2.3 +/- 0.2 mm) showed less mean displacement than did the vertical FasT-Fix or the Viper system groups (3.9 +/- 0.7 mm and 3.9 +/- 0.5 mm, respectively); the vertical mattress suture group (21.8 +/- 2 N/mm) also displayed superior mean stiffness to the vertical FasT-Fix or the Viper system groups (13.2 +/- 2 N/mm and 13.1 +/- 1.8 N/mm, respectively). During load-to-failure testing, the vertical FasT-Fix group (145.9 +/- 9 N) withstood greater mean loads than did the Viper system group (111.2 +/- 30 N), but it did not differ significantly from loads withstood by the vertical mattress suture group (133.4 +/- 10 N). The Viper system and vertical FasT-Fix groups (14.6 +/- 2 N/mm and 12.1 +/- 1 N/mm, respectively) displayed superior mean stiffness to the vertical mattress suture group (9.8 +/- 0.5 N/mm) during load-to-failure testing. CLINICAL RELEVANCE: Standard vertical mattress sutures provided superior fixation during cyclic loading compared with the 2 all-inside methods of suture fixation, suggesting a potential for better meniscal lesion healing with vertical mattress sutures when confronted with the stresses associated with early, progressive rehabilitation activities. Stronger sutures and less meniscal segment purchase in tears located 3 to 4 mm from the periphery may contribute to the failure of the Viper repair system.

Absorbable Implants↗
PubMedDate not supplied

The relationship of the axillary nerve to arthroscopically placed capsulolabral sutures. An anatomic study.

Ten cadaveric shoulders (mean donor age, 60.5 years) underwent arthroscopic placement of capsulolabral sutures as performed during arthroscopic reconstruction for shoulder instability. In relation to the glenoid face, the sutures were placed anterior, anteroinferior, inferior, posteroinferior, and posterior. All sutures entered the capsule approximately 1 cm away from the glenoid and exited beneath the labrum, and were tied using arthroscopic knot-typing techniques. The shoulders were frozen in the lateral arthroscopic position of approximately 45 degrees of abduction and 20 degrees of flexion and sectioned in the plane of the glenohumeral joint. The axillary nerve was then dissected, and the average distance from the nerve to each suture was found to be 16.7 mm at the anterior position, 12.5 mm at the anteroinferior position, 14.4 mm at the inferior position, 24.1 mm at the posteroinferior position, and 32.3 mm at the posterior position. In no specimen was any suture closer to the axillary nerve than 7 mm. We noted a statistically significant trend for the nerve to lie closest to the anteroinferior suture and gradually recede from the remaining sutures lying more posteriorly. This anatomic study is the first to demonstrate a relatively safe margin for arthroscopic suture placement between the capsule and axillary nerve when these sutures are placed approximately 1 cm from the glenoid rim.

Aged↗
PubMed2005

[Evaluation of short-time resorption surgical sutures in tubal anastomoses with use of microsurgical techniques. An experimental study].

In the paper there have been evaluated synthetic absorbable surgical sutures--Coated VICRYL, of short time of their resorption in an organism. The valuation concened their usefulness to carrying out the operations of oviducts with use of microsurgical technique. It consisted in determination of biocompatibility degree of analyzed sutures within tubal tissues and also their technical utility to this kind of procedures. The valuation of the surgical sutures was performed on the ground of experimental studies with use of laboratory animals--New Zealand white female rabbits, in which "end-to-end" microsurgical tubal anastomoses were made, with use of analyzed sutures. In further stage, pathomorphological investigations of the animals were performed (in various time after the operation), during which there were conducted microscopic observations of histologic slides derived from tubal anastomoses regions. The purpose of the work was trying to appoint the most adequate suture material for carrying out the operations of oviducts with use of microsurgical technique. It was also an assistance for an operator to take a decission of choice of the proper surgical sutures for surgical treatment of female mechanical infertility and other kind of microsurgical operations which are performed in gynaecology. Generally good technical utility in microsurgical practice of surgical sutures Coated VICRYL--absorbable of short period of their resorption in tissues was stated. They cause the formation of only single peritoneal adhesions, mainly in the regions of tubal anastomoses previously made and produce relatively small tubal tissue reaction, which testifies to high biocompatibility of the sutures, as the implantation material. The analyzed surgical sutures characterize themselves of very good usefulness to microsurgical operations of oviducts.

Absorbable Implants↗
PubMed1990

Inadequacy of a polyester (Mersilene) suture for the reduction of astigmatism after penetrating keratoplasty.

Through two prospective studies, we evaluated the use of polyester (Mersilene) sutures in penetrating keratoplasty. Study 1 was a randomized comparison of combined running and interrupted Mersilene and nylon sutures (n = 45). Study 2 was a case series of single running Mersilene with postoperative adjustment of suture tension to manage astigmatism (n = 23). Study 1 demonstrated that Mersilene interrupted sutures were 5.5 times more likely to have handling-related complications compared to nylon (P = 0.01); in addition, they were 3 times as likely to have tissue-related complications as nylon interrupted sutures (P = 0.16). Study 2 demonstrated a complication rate of 69% when Mersilene was used as a single adjustable running suture. At 6 months postoperatively, the median refractive astigmatism for the adjustable cases was 3.37 D (mean, 4.03 +/- 2.37 D). Eyes in Study 2 with significant suture-related complications were 2.85 times more likely to have greater than 4 D of refractive astigmatism than were eyes without suture-related complications. We concluded that Mersilene is an undesirable suture for use in penetrating keratoplasty.

Adult↗
PubMed1984

[Diseases caused by sutures following stomach operations--yes or no?].

The importance of remaining suture material in the operated stomach was studied on two groups of patients. Group I consisted of 560 patients who were found among about 6,000 gastroscopically examined patients. Group II consisted of 102 non-selected patients who underwent a gastric operation and in certain intervals were repeatedly examined gastroscopically and clinically after operation. The most frequent gastric operation was Billroth II, followed by Billroth I and the selective proximal vagotomy with pyloroplasty. Group I shows that the proof of suture material in the operated stomach depends on the postoperative time interval. During the first postoperative year the proof is most frequent with 48.5% and permanently decreases in the following years. After the 15th postoperative year no threads were found. Suture material could be more frequently proved in the Billroth I stomach (52.5%) than in the Billroth II stomach (21.7%). In group II in 56% of the patients suture material was found in the stomach. Also here the Billroth I stomach was at the top. The analysis of the complaints in patients with and without suture material resulted in the fact that remaining suture material is responsible for epigastric complaints and complications such as ulcer and haemorrhage. The notion of "thread disease" is justified. The frequency of the symptomatic thread disease during the first two years after operation is 30%. A plan of measures for the decrease of this complication is proposed which among others provides the use of absorbable suture material for all sutures at the stomach and demands the endoscopic removal of all rests of sutures.

Follow-Up Studies↗