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PubMedDate not supplied

A computer system applying the face method to represent multiphasic tests.

The results of medical examinations have recently become multiphasic with few exceptions, and various graphical methods exist to represent the results concisely. One of these graphical methods is reported here, utilizing a computer system for applying the so-called 'face method'. This displays the condition of an individual's health by erythrocyte count, leucocyte count, haemoglobin, erythrocyte sedimentation rate, systolic blood pressure and diastolic blood pressure, all the information being accessible via a database system. Only keywords are necessary to display faces representing the health condition. Graphical methods are useful for providing data features because they appeal to the eye. The face method is more practical than other graphical methods in that its features give easily recognizable indications. The face method can be utilized in various ways, for example in differential diagnosis of anaemia, and to comprehend time-based changes in an individual's health condition based on multiphasic tests.

Biometry↗
PubMedDate not supplied

The use of computerized risk assessment for personal instruction in the primary prevention of ischaemic heart disease in a Japanese Automated Multiphasic Health Testing and Services Center.

The major objectives of ningen dock, or multiphasic health testing and services, have been moving from secondary prevention to primary prevention. The main reason for this is that recently the majority of the diseases involved have been chronic diseases which develop slowly and without visible symptoms--often the patient is unaware of the fact that he has a disease until the disease reaches an advanced stage. Of course such diseases, since they exhibit few or no symptoms, are hard to detect. Secondary preventive care becomes difficult in such a situation, and primary preventive care is even more difficult. The major diseases of this type at present are neoplastic and arteriosclerotic diseases. Secondary prevention, leading to early detection, has proved more effective in treating cases of neoplastic diseases, while primary prevention, with its consequent reduction of risk factors, has proved to be more useful in dealing with arteriosclerotic diseases. It is therefore highly recommended that computers installed for health testing be utilized for evaluating risk factors and presenting the results to the examinees through colour displays and other devices such as primary care instructions for them. It is relatively easy now to collect time series data and store them in computers. For people who have no symptoms or complaints, a combination of personal and group instructional methods is necessary for carrying out primary care health instructions.

Computers↗
PubMed1994

[Changes in electrocardiographic findings with aging in a longitudinal study of 500 apparently healthy persons aged 60 years and older].

A number of studies have been published which have attempted to define the electrocardiographic (ECG) changes with aging, but most of them were obtained from cross-sectional studies. To distinguish ECG changes related to physiological aging from those associated with arteriosclerosis, we assessed the ECG changes of 500 apparently healthy subjects, aged 60 years and older in 1992, who had been followed at the Keio Health Consulting Center for over 15 years. All subjects had no overt cardiovascular diseases in 1992. We compared the ECG in 1992 with that taken over 15 years ago. Changes in ECG during that period were also reviewed. With aging, the mean axis deviated to the left, the mean QTc interval was shortened, and the mean PR interval was prolonged. ST segmental change, atrial overloading, bundle branch block developed newly in 16%, 8% and 7% of, respectively. There were no relationships among axis deviation, PR interval change, or QTc shortening and coronary risk factors. QTc prolongation and ST segmental change were strongly related to hypertension or impaired glucose tolerance. When ECG changes in those under 65 years old were compared with those over 80 years old, the incidence of ST segmental change in those over 80 years old was significant higher. This study was not a prospective study but suggested each type of ECG change related to aging was affected by physiological and/or pathological factors in a distinct way and had different phases of development and progression.

Aged↗
PubMed1999

[Effects of aging and hyperlipidemia on plasma osteopontin level].

In order to elucidate a possible mechanism for accelerated atherogenesis as well as enhanced vascular calcification observed during the normal aging process, we measured plasma osteopontin (OPN) levels and examined their relation to aging and certain disease parameters. In all cases examined, no significant relation was found between the plasma OPN level and age, body mass index, blood pressure, plasma levels of glucose and insulin, serum levels of creatinine, triglyceride, and high density lipoprotein cholesterol. On the other hand, a significant negative correlation was found between the plasma OPN level and serum total cholesterol concentration (n = 78, r = -0.355, p = 0.0014). The serum level of low density lipoprotein (LDL) cholesterol, calculated by the formula of Friedewald, also showed a significant negative correlation to the plasma OPN level (n = 78, r = -0.301, p = 0.0075). In cases without diabetes mellitus and hypertension, a significant positive correlation was found between the plasma OPN level and age (n = 22, r = 0.445, p = 0.0378). It is postulated that OPN plays a negative regulatory role in the development of vascular calcification. Therefore, the observed negative relationship between the plasma OPN level and the serum levels of total cholesterol and LDL cholesterol, suggests a possibility that hypercholesterolemia facilitates vascular calcification by suppressing OPN synthesis. On the other hand, in non-diabetic and normotensive cases, the positive relationship between the plasma OPN level and age may reflect a defense mechanism against age-related increase of vascular calcification.

Aging↗
PubMed1977

Evaluation of automated multiphasic health testing of referred patients by general practitioners.

Seventy-eight general practitioners provided clinical follow-up reports on 752 patients whom they had referred to the Shepherd Foundation, Melbourne, for automated multiphasic health tests (AMHT). One or more new diagnoses were reported in 270 cases (36%). The yield of new diagnoses made as a result of AMHT was a function of sex, but not of age or pre-referral status. Additional useful information relevant to a previously known diagnosis was reported in 234 cases (31%) and other benefits in 185 cases (25%). Patients were significantly reassured in 623 cases (83%) while disadvantages were reported in 41 cases (5%).

Adult↗