[A view of adaptation from the position of Markov processes].
Explore the source record for details and available documents.
SEARCH · Search PubMed
Search indexed PubMed citations on genomics, clinical trials, systematic reviews and public health. Explore titles, authors and supplied subject terms, then open the PubMed record.
Quote a phrase for an exact phrase match. Source license links do not imply unrestricted reuse.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
In this study we measured the blood glucose before and after diagnostic upper GI endoscopy as an index of the stress induced by the procedure. The possible influence of various premedications in the blood glucose was also studied. One hundred and twenty consecutive non-diabetic patients of both sexes aged 20-75 years were randomly allocated into four groups (A,B,C,D) according to the premedication used. Sixty non-diabetic patients, who were not endoscoped, were allocated into three groups (C1, C2, C3) and served as controls. Blood glucose increased significantly in the patients but not in the controls. No correlation was found between the changes in the blood glucose and the time needed for the endoscopy. Changes in the blood glucose did not differ among the patients (F = 0.214; p = 0.886) irrespective of the premedication; however the increase was numerically less when 10% lidocaine spray was used as a premedication (Groups A and C). It is concluded that diagnostic upper GI endoscopy induced a significant increase in blood glucose, irrespective of the premedication. This increase seemed to be mainly the result of the stress induced by the irritation of the pharynx during the intubation.
Adaptation processes in an acute stress situation were investigated an compared in young and elderly subjects. Insulin hypoglycemia was used to provoke stress. The behavior of the blood sugar after administration of 0.1 U/kg old insulin shows a marked hypoglycemic state after 30 minutes, both in the young and in the older subjects. The rise into the normal range occurs considerably quicker in the young than in the elderly. Adrenaline excretion is distinctly lowered in older people. Measurement of hydrocortisone excretion also shows a lower reaction level and a delayed onset in the elderly. Growth hormone analysis shows a smaller production in advanced age. It is consequently established that adaptation potential decreases in old age.
Blood pressure, heart rate, respiration frequency and ECG parameters were measured in 3 juvenile male rhesus monkeys under acute and chronic influence of a stepped load schedule including positive (nutritional), negative (pain-related) and socially operant conditioning and phases of a pharmacological sensibilization (angiotensin-II) of the cardiovascular system. The results suggest a general adaptation to the positively operant conditioning, while the latter stressing influences (either single or in combination) produced blood pressure and heart rate elevations, which had the character of dysregulatory functional changes (borderline hypertension model) and were reached by other authors, if at all, only through stronger stress influences.
Pathological general adaptive reactions of the body (GARs) were found out to occur on 33.8 +/- 5.0 of patients with chronic pathologies of the urinary and digestive organs, arriving at the Truskavets health resort from the areas contaminated with radionuclides, compared with 7.0 +/- 2.1% of diseased controls. Complex spa treatment during a period of two weeks involving ingestion of the mineral water "naftusia" has a beneficial effect on pathologic and premorbid GARs though not effectively so. Adaptogenic effect of balneotherapy is potentiated by use of balsam "Kryms'kyĭ" but not a home preparation ginseng.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
A large body of data has been accumulated concerning physiological responses in people exposed to stressors in laboratories. Adrenaline and cortisol have become known as "stress hormones" because, in men, levels of both hormones consistently rise in response to stress in laboratory-based investigations. If chronically repeated, elevation of adrenaline and cortisol is likely to have long-term consequences for health, especially cardiovascular health, partly via the effects of the hormones on blood pressure and serum cholesterol levels. Research on people conducting their everyday lives is necessary to establish whether the same responses are shown on a day to day basis. Such research requires new methodologies and careful data collection. So far, it has been shown that adrenaline and blood pressure do seem to vary in expected ways. Other responses in everyday life, including those of cholesterol, cortisol and the immune system, are less well characterised.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
Explore the source record for details and available documents.