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At least 775 records · Page 43Linked to original sources
PubMed1993

Eugene J. Keefe Memorial Lecture. The Canadian health care system: an overview.

Canada has 21 years of experience with a national health care insurance program. This lecture describes the program, its evolution, financing, and attitudes and perceptions of the consumer, the provider (physicians and hospitals), and the funding agencies (governments). Comparisons, where appropriate, with the system in the United States are incorporated.

Canada↗
PubMed1994

Eugene W. Caldwell Lecture. Clinical efficacy of diagnostic imaging: love it or leave it.

The traditional goal of radiology has been to provide images of the highest technical quality that permit the most accurate diagnoses possible. From a more global perspective, diagnostic radiology is part of a larger system that has as its goal effective and efficient treatment of patients. A six-tiered hierarchical model of efficacy that includes this more global view is presented. This model is intended to improve understanding of the continuum that efficacy is and to conceptually relate efficacy to technology assessment and outcome research. Better understanding of efficacy/technology assessment and outcome research fostered by the model should encourage radiologists to participate actively in federally supported research in these areas. Those radiologists who do so will come to understand better how radiology can help patients and society as a whole. Use of the model's concepts should also aid radiologists in becoming more effective consultants to their clinical colleagues about optimal use of high-technology imaging from the perspectives of clinical efficacy, patient outcome, and societal efficacy.

Cost-Benefit Analysis↗
PubMed1994

Eugene W. Caldwell Lecture. Technology: the key to controlling health care costs in the future.

The American health care financing system is in a state of crisis. The rising cost of health care and the progressive difficulty Americans are experiencing in accessing the system have produced a great national debate concerning the future of medicine in America. Current health care cost trends, which are not sustainable, are projected to consume 37% of the gross national product by the year 2030. The financing system that supports the health care system is failing. The number of uninsured residents is growing more than twice as fast as the number with health insurance. The legitimate concern about the spiraling cost for medicine has focused attention on seeking root causes. Critics have focused on technology as the single most important factor in driving the cost trends in medicine upward. They have concluded that "long-term control of the rate of increase in expenditures requires that we curb the development and diffusion of clinically useful technology." These critics have not made their case, because they base their conclusions on hospital-derived data. These data are inaccurate because of the phenomenon of "cost-shifting." The critics do not examine the important issue of productivity and do not have reliable data on the costs and benefits of new technologies. Finally, the critics do not take into account the issue of use and abuse of technology. This is particularly important in the ambulatory environment. To break the health care cost spiral, radiologists, as the keepers of new technology, must commit themselves to at least four fundamental initiatives. The current American hospital-based health system must be replaced with an ambulatory system; productivity must be the primary business goal for radiologists; pricing of new services should reflect actual resources consumed, not the in-patient services displaced; and radiologists must reassert their role as doctors' doctors. The health care cost spiral is a real national crisis. The mission for radiology is to introduce the minimally invasive, ambulatory system of the future. The costs for delivering care within the new system will be a fraction of former costs. My assignment is to present a perspective on the role radiology must play in introducing new imaging technology to medicine. One of the distinguishing features of American society is its fascination with technology. It is only natural that the American health care system reflects this orientation.

Cost Control↗
PubMed1995

Eugene W. Caldwell Lecture. The American Journal of Roentgenology: past, present, and future.

In November 1895, a German physicist named Wilhelm Conrad Roentgen read before the Physico-Medical Society of Würzburg a paper reporting his discovery of a new type of radiation that he called X-rays. Only 11 years later, the American Journal of Roentgenology began to chronicle progress in the new science of roentgenology, and it has continued to fulfill this mission for 89 of the 100 years since Roentgen's discovery. My purpose in this address is to focus attention on the AJR as part of the centennial of the discovery of the X-ray. I wish to pay tribute to the Journal as a vital part of the American Roentgen Ray Society (ARRS), and--most important--to acknowledge it as a priceless archive and a treasured heritage to be passed on to future generations of all radiologists. I will recognize the contributions of the key people in the recent history of the AJR who have made the Journal what it is today, reflect on the changes that have occurred during my tenure as editor, and finally, discuss the challenges that I think the Journal will face in the future. This constitutes my valedictory report--my farewell reflections on the Journal, now that my tenure as editor is ending on July 1, 1995.

Forecasting↗
PubMedDate not supplied

Eugene L. Opie.

Explore the source record for details and available documents.

Diabetes Mellitus↗
PubMedDate not supplied

Eugene Robertson Special Lecture. Hyperthermia from the clinic to the laboratory: a hypothesis.

Recently reported thermal isoeffective dose-response relationships in human tumours confirm the existence of an effect of hyperthermia in combination with radiotherapy. The prognostically important thermal doses are based upon the lowest temperatures achieved within tumours, and these thermal doses are well below those used in most laboratory studies that have provided the rational for hyperthermia treatment. Direct thermal cytotoxicity and thermal radiosensitization are insignificant at these low thermal doses. Other explanations for the mechanism of hyperthermia effect appear warranted. We hypothesize that hyperthermia at low thermal doses causes reoxygenation and hence direct radiosensitization in vivo.

Animals↗
PubMed1997

The Eugene M. Landis Award Lecture 1996. Delivery of molecular and cellular medicine to solid tumors.

To reach cancer cells in a tumor, a blood-borne therapeutic molecule or cell must make its way into the blood vessels of the tumor and across the vessel wall into the interstitium and finally migrate through the interstitium. Unfortunately, tumors often develop in ways that hinder each of these steps. Our research goals are to analyze each of these steps experimentally and theoretically and then integrate the resulting information in a unified theoretical framework. This paradigm of analysis and synthesis has allowed us to obtain a better understanding of physiologic barriers in solid tumors and to develop novel strategies to exploit and/or to overcome these barriers for improved cancer detection and treatment.

Animals↗