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At least 775 records · Page 43Linked to original sources
PubMed1994

Low surface tension calcium hydroxide solution is an effective antiseptic.

The antimicrobial effects of a saturated calcium hydroxide solution, and in combination with 10% and 20% detergent, were evaluated on Streptococcus faecalis, Streptococcus sanguis, Streptococcus mutans, Streptococcus salivarius, Neisseria sp., diphtheroid, Staphylococcus aureus, Lactobacillus sp., Staphylococcus epidermidis, Bacillus subtilis and Candida albicans. The saturated calcium hydroxide solution was effective against only four of the 11 microorganisms studied over a 60-min exposure time. The calcium hydroxide solutions containing detergent killed all 11 test organisms over a 30-min exposure time. This difference was statistically significant (P < 0.01). No statistically significant difference in antimicrobial action was found between the 10% and 20% detergent calcium hydroxide solutions (P > 0.01). However, the low surface tension (46.5 x 10(-3) Nm-1) and high pH (10.8) of the calcium hydroxide solution with 20% detergent establish it as the more effective solution.

Anti-Infective Agents, Local↗
PubMed1984

The antimicrobial properties of two commonly used antiseptic mouthwashes--Corsodyl and Oraldene.

The antimicrobial activities of the mouthwashes Corsodyl and Oraldene against common buccal organisms were essentially similar. The concentration of the active substance in the two mouthwashes was well in excess of the minimum inhibitory concentrations determined. Also a rapid lethal effect on the bacteria was found which, when combined with the previous property, may well account for the usefulness of these products in infectious conditions.

Bacteria↗
PubMed1992

Evaluation of the repeatability and reproducibility of European suspension test methods for antimicrobial activity of disinfectants and antiseptics.

A collaborative study to determine the precision of the 1987 Method of test for the antimicrobial activity of disinfectants in food hygiene is described. The repeatability and reproducibility of the test was found to vary according to the nature of the test organism, the type of disinfectant product and the skill of the operator. Results indicate that significant differences in microbicidal effect (ME values) occur within test laboratories between test periods as well as between laboratories, and that much of this variability derives from apparently random variations in the resistance of test strains from day to day and test period to test period. Indications are that although the test is sufficiently reliable to be used as a standard method, adequate test replication must be specified to distinguish borderline pass from borderline fail disinfectant concentrations. The implications of the results in relation to current work on the development of unified European test methods for disinfectants is discussed.

Analysis of Variance↗
PubMed1981

Comparison of the bisbiguanide antiseptics alexidine and chlorhexidine. I. Effect on plaque accumulation and salivary bacteria.

A blind crossover trial was carried out to compare the effects of a 0.2% chlorhexidine gluconate mouthrinse and a 0.035% alexidine mouthrinse on plaque accumulation and salivary bacteria in a group of volunteers. The subjects refrained from all forms of oral hygiene during two 10-day periods and rinsed twice a day with the mouthwash randomly allocated to the respective period. Prerinse, day 4 and day 10 total salivary aerobic and anaerobic bacterial counts were determined during each period. Plaque scores were recorded at the end of each 10-day period. Significantly more plaque accumulated in subjects rinsing with alexidine when compared with chlorhexidine. Significant and comparable reductions in salivary bacterial counts were observed with both chlorhexidine and alexidine on day 4 and day 10 when compared with pre-rinse counts. Although at the concentrations used alexidine was less effective than chlorhexidine, it may be of value as a short-term adjunct to oral hygiene.

Adult↗
PubMed1989

Soap pH and the effectiveness of alcoholic hand antiseptics.

This study was done to investigate if the pH-value of a soap used for handwashing had any effect on the immediate and the prolonged effectiveness of alcoholic hand disinfectants. One acidic soap (pH = 3.5) and one alkaline soap (pH = 8.5) were tested in combination with 70% and 90% ethanol and alcoholic chlorhexidine. Bacterial counts from the hands of 26 test persons were obtained using the fingerprint method. The fingerprints were taken before and after handwashing, after hand disinfection and after 3 h of wearing sterile latex gloves. The results showed that soap pH did not influence significantly the effectiveness of a subsequent hand disinfection. The combined use of alkaline soap and alcoholic chlorhexidine showed a tendency to smaller variation in bacterial reduction and greater effectiveness. This combination was the only one that led to an increased bacterial reduction after 3 h.

Alcohols↗