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[Development of neck filters for reducing artifact in cervical bone SPECT].

In cervical bone scintillation SPECT studies using TEW and OS-EM methods, we have observed an artifact that may interfere with evaluation of the image; higher accumulation in cervical vertebra compared with in the head and thoracic vertebra. As the neck is smaller in diameter than in the thorax and head, gamma ray absorption is lower. In addition, as the distance between the neck and the detector is greater, scattered gamma rays are increased, interfering with imaging and causing artifact. To overcome these problems, we have developed special absorbers (neck filter) to make the relative absorption level of the neck comparable to that of the head and thorax and have employed these cervical filters in bone scintillation SPECT studies in combination with TEW scatter correction and OS-EM method. Our results showed that artifacts were significantly reduced and satisfactory images were obtained.

Artifacts↗

Comparison of the shock artifacts induced by tripolar and bipolar electrical stimulation techniques.

Tripolar and bipolar electrical stimulation procedures were performed on the upper limbs of eight subjects. The mid-forearm was stimulated electrically (tripolar or bipolar) by surface electrodes, and the induced stimulus shock artifacts were recorded simultaneously from the wrist and elbow. During tripolar stimulation, two types of stimulating configurations were utilized: with the center electrode designated as the cathode and the two outermost electrodes connected to a common anode, and vice versa. During bipolar stimulation, the center electrode served as one pole of the stimulator, and one of the two outermost electrodes of the tripolar stimulator was disconnected. The stimulus intensity was kept constant in all stimulating procedures. Artifacts were reduced significantly during tripolar compared to bipolar stimulation, if the outermost electrodes of the tripolar stimulator (which were facing the recording electrodes) were also oriented toward the recording sites during bipolar stimulation and had the same stimulus polarity. Artifacts were slightly reduced in amplitude from tripolar stimulation, if the center electrode were oriented toward the recording sites during bipolar stimulation and had the same stimulus polarity as previously used during tripolar stimulation.

Adult↗

Poststress motionlike artifacts caused by the use of a dual-head gamma camera for (201)Tl myocardial SPECT.

UNLABELLED: When performing (201)Tl myocardial SPECT using a dual-head gamma camera on patients after exercise stress, we have observed in some a sudden increase in the counting rate between the 16th and 17th images. This increase provoked motionlike artifacts, which increased the number of false-positive findings. The aim of our study was to determine possible causes for this leap in activity. METHODS: We performed myocardial SPECT using a dual-head gamma camera on 110 patients after exercise stress: in 38 patients approximately 5 min after injection (group 1), in 43 patients approximately 14 min after injection (group 2), and in 29 patients twice, at approximately 5 and 20 min after injection (group 3). We also performed dynamic data acquisition for 10 min on 18 patients after exercise stress. We compared activity in the heart region in image series obtained after exercise stress and at rest. RESULTS: Daily quality control tests eliminated the possibility of any malfunctions of the gamma camera. Careful image analysis showed no visible patient motion. Our results showed that upward creep of the heart could not be a cause of the described phenomenon. After exercise stress, a > or = 5% activity leap in the heart region on the 16th and 17th frames was more frequent in group 1 than in group 2. Two consecutive acquisitions after exercise stress showed that the leap was >5% in 24 patients (83%) and 12 patients (41%) at the first and second acquisitions, respectively (group 3). In all patients, the leap was <5% at rest. Dynamic studies showed that the activity in the heart region steadily decreased in all patients after exercise stress. We suggest that decreasing (201)Tl concentrations in myocardium or blood could be a major reason for the described artifacts. CONCLUSION: We proposed that the pharmacokinetics of (201)Tl-chloride be evaluated within a short time after injection in humans after exercise stress. Now, in our department, we have begun acquisition approximately 12 min after (201)Tl administration, and the above-mentioned phenomenon has not appeared. However, to avoid the artifacts caused by early redistribution of (201)Tl, acquisition must not begin too late.

Artifacts↗

[Elimination of electrocardiogram artifacts from electroencephalogram records by using the simultaneously recorded electrocardiograph data].

We developed a simple method to eliminate electrocardiogram (ECG) artifacts from electroencephalogram (EEG) records by using simultaneously recorded ECG data. The raw EEG data, the real EEG data and the ECG data were regarded as multi-dimensional vectors Ea, Er and C, respectively. Also, the ECG data, with reduced amplitude whose coefficient was denoted as 'k', were assumed to be overlapped on the real EEG. These assumptions introduced the equations [Ea = Er + k.C], [Er.C = 0] and finally [k = Ea. C/C.C]. This calculation method was implemented by a Macintosh computer using data exported from digital EEG recordings (sampled at 200 Hz with 16-bit resolution). In several subjects, sampling intervals of 5 or 10 seconds for calculation succeeded in eliminating ECG artifacts. However, regardless of the sampling interval, this elimination condition was not always efficient in several other subjects, including a brain-dead patient. It was suggested that the ECG data used were insufficient for the calculation, because only one hand-to-hand reference was used for simultaneous recording, as usual. This one ECG reference was able to express only one ECG projection. Then two other hand-to-foot references of ECG were added to the recordings, and the elimination procedure was performed using all of the simultaneously recorded ECG data at the three references. Consequently, elimination was much improved in most subjects, including the brain-dead patient. Our method may be useful for eliminating ECG artifacts without changing reference electrodes.

Artifacts↗

Correction for oral contrast artifacts in CT attenuation-corrected PET images obtained by combined PET/CT.

UNLABELLED: Recent studies have shown increased artifacts in CT attenuation-corrected (CTAC) PET images acquired with oral contrast agents because of misclassification of contrast as bone. We have developed an algorithm, segmented contrast correction (SCC), to properly transform CT numbers in the contrast regions from CT energies (40-140 keV) to PET energy at 511 keV. METHODS: A bilinear transformation, equivalent to that supplied by the PET/CT scanner manufacturer, for the conversion of linear attenuation coefficients of normal tissues from CT to PET energies was optimized for BaSO(4) contrast agent. This transformation was validated by comparison with the linear attenuation coefficients measured for BaSO(4) at concentrations ranging from 0% to 80% at 511 keV for PET transmission images acquired with (68)Ge rod sources. In the CT images, the contrast regions were contoured to exclude bony structures and then segmented on the basis of a minimum threshold CT number (300 Hounsfield units). The CT number in each pixel identified with contrast was transformed into the corresponding effective bone CT number to produce the correct attenuation coefficient when the data were translated by the manufacturer software into PET energy during the process of CT attenuation correction. CT images were then used for attenuation correction of PET emission data. The algorithm was validated with a phantom in which a lesion was simulated within a volume of BaSO(4) contrast and in the presence of a human vertebral bony structure. Regions of interest in the lesion, bone, and contrast on emission PET images reconstructed with and without the SCC algorithm were analyzed. The results were compared with those for images obtained with (68)Ge-based transmission attenuation-corrected PET. RESULTS: The SCC algorithm was able to correct for contrast artifacts in CTAC PET images. In the phantom studies, the use of SCC resulted in an approximate 32% reduction in the apparent activity concentration in the lesion compared with data obtained from PET images without SCC and a <7.6% reduction compared with data obtained from (68)Ge-based attenuation-corrected PET images. In one clinical study, maximum standardized uptake value (SUV(max)) measurements for the lesion, bladder, and bowel were, respectively, 14.52, 13.63, and 13.34 g/mL in CTAC PET images, 59.45, 26.71, and 37.22 g/mL in (68)Ge-based attenuation-corrected PET images, and 11.05, 6.66, and 6.33 g/mL in CTAC PET images with SCC. CONCLUSION: Correction of oral contrast artifacts in PET images obtained by combined PET/CT yielded more accurate quantitation of the lesion and other, normal structures. The algorithm was tested in a clinical case, in which SUV(max) measurements showed discrepancies of 2%, 1.3%, and 5% between (68)Ge-based attenuation-corrected PET images and CTAC PET images with SCC for the lesion, bladder, and bowel, respectively. These values correspond to 6.5%, 62%, and 66% differences between CTAC-based measurements and (68)Ge-based ones.

Administration, Oral↗

The compensation of head motion artifacts using an infrared tracking system and a new algorithm for fMRI.

We aim to provide a next generation Magnetic Resonance Imaging (MRI) technology with an integrated solution for reducing motion artifacts in brain imaging applications. New developments in the field of MRI are revolutionizing the diagnostic capabilities e.g. of functional (fMRI) of the technique. Unfortunately, motion artifacts are eminent problems in cerebral MRI images, especially in difficult patient populations (e.g. chronic pain, children, neonates). Patient motion artifacts are present in 2D sequences, but are extremely detrimental in multi-slice 3D sequences often employed in fMRI. The problem of motion compensation in MRI technology deals with: Identification of the source as well as pattern of motion. Obtaining a mathematical model of motion that can be used to identify and then compensate the motion effects. Optimizing the image acquisition sequence in order to minimize, or even eliminate, the effect of motion. We propose a method to obtain a quantitative measure of the movement of the head between different data acquisition points in both MRI, and functional MRI examination.

Algorithms↗

Arterial pulse as a rare artifact observed on electronystagmography.

We report a rare artifact observed during electronystagmography (ENG) in a 54-year-old woman. Rhythmic waves were seen on ENG even though no corresponding movements of the eyes or eyelids were detected, even by infrared camera monitoring. The rhythmic waves corresponded to the patient's pulse and occurred after the appearance of each QRS complex on electrocardiography (ECG). The waves were believed to have been generated by the pulse of the artery near the electrodes, which represented contamination of plethysmography at the temple. To the best of our knowledge, such an artifact has not been previously reported in the literature. When rhythmic waves unrelated to eye movements are recorded during ENG, an artifact of cardiovascular origin should be ruled out, and ECG and direct observation of the eyes are necessary.

Artifacts↗

Image artifacts in fast magnetic resonance imaging.

Image artifacts are unwanted, spurious signal intensities that interfere with clinical diagnosis. This article gives an overview of image artifacts in magnetic resonance imaging. We discuss the causes of these artifacts, provide clinical examples, and offer solutions to avoid them.

Artifacts↗

EMG vagus nerve stimulator artifact.

EMG artifact produced by a VNS stimulator is described. A patient with a VNS stimulator underwent an EMG study for suspected ALS. Artifacts that appeared similar to positive sharp waves or fibrillations were noted that could produce a false clinical diagnosis. These VNS-EMG artifacts matched well with the VNS generator's set parameters. We conclude that EMG findings must be interpreted with caution in patients with VNS implants and also that EMG may have a possible monitoring value for VNS activity.

Action Potentials↗

Image reconstruction using filtered backprojection and iterative method: effect on motion artifacts in myocardial perfusion SPECT.

UNLABELLED: Patient motion during myocardial perfusion SPECT is a common source of errors. The extent and severity of motion artifacts have been described for filtered backprojection (FBP) reconstruction. In recent years, iterative reconstruction has been used increasingly in reconstruction of myocardial perfusion SPECT images and has been shown to be more accurate than FBP even in cases of incomplete datasets. This study evaluated the effect of iterative reconstruction on the extent and severity of motion artifacts. METHODS: Six normal, motion-free, and nongated (99m)Tc myocardial perfusion SPECT scans were selected, and simulated motion of 3 pixels was applied to the early, middle, and late phases of acquisition in 2 types of movement, returning and nonreturning. The images were acquired by a single-head gamma-camera in 32 steps at 30 s per step and in a 180 degrees arc from right anterior oblique to left posterior oblique. All original and shifted images were reconstructed using FBP and ordered-subset expectation maximization (OSEM) techniques and interpreted by 2 nuclear medicine specialists qualitatively and semiquantitatively (using 17 segments and a 5-point scoring system). RESULTS: Overall, 68.1% and 70.8% of shifted images were categorized as definitely abnormal in the FBP and OSEM reconstructions, respectively (P > 0.5). The mean summed score was 11.9 (+/-5.7) and 11.3 (+/-5.2) for nonreturning shifted images (P = 0.13) and 5.2 (+/-2.4) and 3.9 (+/-2.0) for returning shifted images (P < 0.001) in the OSEM and FBP reconstructions, respectively. The incidence of defects in different myocardial segments was similar with the 2 reconstruction methods. The summed score was higher with shifting in the middle phase of acquisition than in the late or early phase. CONCLUSION: Our study showed that the incidence of abnormal findings and the location of defects were not different between the 2 reconstruction types; however, with semiquantitative assessment, the severity of defects increased with OSEM reconstruction. Although OSEM reconstruction has been reported to be more tolerant to missing data than is FBP reconstruction, our study showed that OSEM reconstruction may be less tolerant to motion artifacts than is FBP reconstruction.

Algorithms↗

Magnetic resonance techniques and artifacts.

One area in which MR imaging can use improvement is the reduction of artifacts due to various physiologic motions during imaging. These artifacts degrade images and can cause misleading interpretations. This paper reviews some of the recent technical advances directed to remove these artifacts, as well as other techniques that improve MR imaging quality in general.

Artifacts↗

Using gated technetium-99m-sestamibi SPECT to characterize fixed myocardial defects as infarct or artifact.

UNLABELLED: Perfusion-scan fixed defects may result from soft tissue attenuation, decreasing test specificity for coronary disease and myocardial infarction (MI). Gated 99mTc-sestamibi SPECT may help differentiate MI from artifact since fixed defects with decreased function (wall motion and thickening) probably represent MI, whereas attenuation artifacts either have normal function or at least do not demonstrate markedly reduced function. METHODS: Ungated resting and gated stress 99mTc-sestamibi SPECT was performed in 551 consecutive patients referred for evaluation of coronary disease. From resting and summed gated stress images, 180 patients (33%) were identified with isolated fixed defects. Function of the defects was assessed subjectively from gated stress images and results were correlated with clinical (history and/or ECG Q-waves) evidence of MI. RESULTS: Of 102 patients with fixed defects and clinical MI, 98 (96%) had abnormal defect function. Of 78 patients with no clinical MI, 18 (23%) had decreased function of the defect, possibly indicating silent MI. In 60 of the 78 patients (77%) with no clinical MI, defect function was normal. Because most (91%) of fixed defects with normal systolic function occurred in women with anterior fixed defects (48%) or men with inferior fixed defects (43%), these were most likely attenuation artifacts. By reclassifying patients with fixed defects and normal function as normal, patients with unexplained fixed defects (no clinical MI) decreased from 14% to 3%. CONCLUSION: Gating provides a valuable adjunct to 99mTc-sestamibi SPECT in characterizing fixed defects and potentially improving test specificity.

Artifacts↗

Reducing motion artifacts during hepatic DSA.

In hepatic digital subtraction angiography, artifacts caused by diaphragmatic motion can interfere with the correct diagnosis of hepatic lesions. This article describes the feasibility of using the exhalation holding method in reducing diaphragmatic motion artifacts in hepatic DSA. The authors compared respiratory holding methods in 30 patients who underwent hepatic DSA. They performed a blind comparison of images to assess diaphragmatic motion artifacts. Results showed the images obtained by the exhalation holding method were superior to those obtained by the inhalation holding method in 20 out of 30 series (66.7%).

Adult↗

[Ultrasonic imaging artifacts. Physical bases].

This review describes frequently visualized and clinically relevant artifacts in ultrasound imaging. The imaging artifacts are categorized by their underlying physical or technical causes, such as: multiple reflections, non-linear propagation direction of the sound, sound beam diameter and pulse length, attenuation, interference, range ambiguity and propagation speed. Examples are given, and procedures that help to minimize imaging artifacts are discussed.

Artifacts↗

Metallic postoperative artifacts on cervical MR.

Spectroscopy of cervical diskectomy specimens obtained from sheep demonstrated that metallic susceptibility artifacts are produced by microscopic amounts of nickel, copper, and zinc. Sufficient quantities of metals to produce artifacts are deposited only by contact of metal drill bits and suction tips. If these instruments do not come in contact during surgery, susceptibility artifacts are not observed.

Animals↗

Attenuation artifacts in SPECT: effect of wrap-around lung in 180 degrees cardiac studies.

UNLABELLED: We estimated that in 75%-90% of PET 82Rb patients the left lung appeared to wrap around the anterior aspect of the left ventricle. We used clinical PET 82Rb myocardial perfusion studies as the input to a SPECT computer simulation model to determine if patients with left lung wrap-around displayed consistent artifacts in reconstructed SPECT images. In particular, we sought an explanation for the hot lateral wall seen in SPECT images from normal female and male patients. METHODS: Attenuated SPECT 201Tl emission data were simulated from a mid-ventricular slice in 10 randomly selected clinical PET 82Rb studies with left lung wrap-around. In these same cases, the influence of left lung wrap-around was removed by assigning the left lung an attenuation coefficient which matched that of the heart. Five randomly selected clinical PET 82Rb studies without left lung wrap-around were also processed with our model. RESULTS: In all 10 cases with left lung wrap-around, reconstructed SPECT images showed the hot lateral wall artifact with a mean septal-to-lateral wall count ratio of 0.86. With left lung wrap-around removed in the same 10 patients, reconstructed images did not show hot lateral wall (mean septal-to-lateral wall count ratio = 1.07). The 5 cases without left lung wrap-around did not show hot lateral wall (mean septal-to-lateral wall count ratio = 1.04) and the ratios changed little with the filling of the left lung (mean septal-to-lateral wall count ratio = 1.05). CONCLUSION: Results of our PET-to-SPECT computer simulation model showed that the hot lateral wall artifact found in SPECT myocardial perfusion images was related to the orientation and positions of the left ventricle and the left lung.

Artifacts↗

MR artifacts, heat production, and ferromagnetism of Guglielmi detachable coils.

The Guglielmi detachable coil, a platinum microcoil used in the endovascular treatment of intracranial aneurysms, was studied in vitro for its MR imaging artifacts, heat production, and ferromagnetism. In addition, imaging artifacts were studied in vivo in eight patients who had undergone therapeutic placement of these coils. These devices displayed a very low level of MR artifact and no ferromagnetism or heat production. We conclude that the Guglielmi detachable coil is compatible with MR imaging in terms of both safety and image quality.

Aneurysm, Ruptured↗

Dental bur fragments causing metal artifacts on MR images.

PURPOSE: Our purpose was to define the role of dental bur fragments in producing metal artifacts on MR images. METHODS: Dental prosthetic reconstructions were made for two dogs. The two lower second premolars were prepared for full-cast crowns by using a diamond bur. The crown margin was placed subgingivally on the right side (1 mm below the free gingival margin) and at the same level as the free gingival margin on the left side. After 1 week, full-cast crowns were cemented in place. MR imaging was performed 7 days later. RESULTS: Metal artifacts appeared in both second premolar regions of the mandible on MR images, with the right side, in which the crown margin was positioned subgingivally, displaying a larger signal distortion than the left side. After removal of the crown, the artifact remained on the right. On histopathologic examination, bur fragments were detected in the gingiva, more on the right than on the left. X-ray fluorescent element analysis showed iron in the gingival tissue containing bur fragments. CONCLUSION: Distortion of MR images was considered to be attributable in part to the damage of the gingiva and in part to the presence of dental bur fragments.

Animals↗