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At least 757 records · Page 42Linked to original sources
PubMed1998

Phosphatidylinositol transfer proteins: the long and winding road to physiological function.

Phosphatidylinositol transfer proteins (PITPs) have historically been thought to help execute lipid-sorting events by transporting phospholipid monomers between membrane bilayers. Recent data, however, indicate unanticipated roles for PITPs in the coordination and/or coupling of phospholipid metabolism with vesicle trafficking and the downregulation of signal-transduction reactions. We are only now beginning to appreciate both the identities of PITP-dependent cellular reactions and the intriguing mechanisms by which PITPs execute their functions in eukaryotic cells.

Biological Transport↗
PubMed1998

The answer is blowing in the wind: a pedunculated tumour with saw tooth flow-volume loop.

Obstructing tumours of the upper airways have been demonstrated to alter the flow volume loop of pulmonary function testing. These alterations could be clues to the nature and location of the obstruction. This report describes a case of a pedunculated squamous cell carcinoma arising in the pharynx whose flow volume loop showed a saw tooth pattern which reflected the location and structure of the tumour.

Airway Obstruction↗
PubMed1998

Dust in the wind.

Explore the source record for details and available documents.

Aerosols↗
PubMed2001

Workplace tobacco policy: progress on a winding road.

This is a report of a pre- and post-intervention telephone survey to track changes in workplace tobacco policy in Pima County, Arizona, from 1997 to 1999. During this period, an extensive effort was made to assist workplaces to establish and enforce formal tobacco use policies. A random sample of 1134 workplaces, stratified by workforce size, was surveyed in 1997. Complete interviews were conducted with 934 (82.4%) workplaces. All 934 workplaces were contacted for the follow-up survey that was conducted in 1999. Of these, 824 (88.2%) completed follow-up surveys. The analyses presented were conducted on businesses that were included in both the baseline and follow-up surveys, and that reported having at least one employee on-site (n = 813). Tobacco policies and smoke-free policies were more likely to be found in larger businesses and businesses with a predominantly female workforce. There was no clear policy progression from having no policy, to having a policy, to becoming smoke-free. There was a small but significant overall decrease (4.8%) in the proportion of businesses having policies in the last two years. We found that 10.3% (75) of businesses that had policies in 1997 had dropped their policies by 1999, and that 13.4% (73) of worksites that were smoke-free in 1997 retained tobacco policies but were not smoke-free in 1999. However, formalization of policy in writing and the number of enforcement strategies utilized increased. These findings suggest that efforts to encourage businesses to establish workplace tobacco policies must be sustained even after policies have been established.

Arizona↗
PubMed1984

Winding one's ps and qs: mental rotation and mirror-image discrimination.

Subjects were timed as they made judgments about ps and qs (also interpretable as ds and bs) in different angular orientations. Whether these judgments were left-right mirror-image discriminations (b vs. d or p vs. q) or up-down mirror-image discriminations (b vs. p or d vs. q), the subjects' reaction times increased sharply with the angular departure of each letter from its designated normal upright orientation, a fact implying mental rotation. This was so whether the subjects responded with the letter labels themselves (e.g., b vs. d) or with the labels left versus right or top versus bottom. It was again the case when the letters were replaced by nonletter forms, in which event there was also a left visual-field advantage in reaction time. This study is therefore the first to demonstrate a mental-rotation strategy when the canonical forms to be discriminated are up-down mirror images as well as when they are left-right mirror images. In both cases, however, the task requires the ability to tell left from right, and we suggest that this is the critical ingredient that induces mental rotation.

Adult↗