Search PubMed⌕ Search

SEARCH · Search PubMed

Results for “Tuberculosis, Lymph Node”

Search indexed PubMed citations on genomics, clinical trials, systematic reviews and public health. Explore titles, authors and supplied subject terms, then open the PubMed record.

Quote a phrase for an exact phrase match. Source license links do not imply unrestricted reuse.

At least 757 records · Page 42Linked to original sources
PubMed1975

Effect of decalcifying agents on the staining of Mycobacterium tuberculosis.

Lymph nodes from guinea pigs inoculated with Mycobacterium tuberculosis were fixed in buffered formalin, then treated for the recommended times in Gooding and Stewart's fluid, EDTA, aqueous nitric acid, von Ebner's fluid, and rapid decalcifier (RDC). The blocks were processed to paraffin wax and sections were stained by the Ziehl-Neelsen technique. Only in sections of the blocks treated with RDC were no acid alcohol fast bacilli demonstrable. Hydrochloric acid is a known constituent of RDC and it was found that Myco. tuberculosis is altered by treatment with 2-5M solutions of hydrochloric acid and above and cannot subseuqently be demonstrated by the Ziehl-Neelsen stain. From these results it is recommended that calcified tissue from patients in whom there is a suspicion of tuberculosis should be decalcified with an agent other than RDC.

Animals↗
PubMed2002

Tuberculosis in children--what has changed in last 20 years?

Several changes have been observed in the epidemiology, clinical manifestations, diagnostic modalities and treatment of tuberculosis. Emergence of HIV epidemic and drug resistance have posed significant challenges. With increase in number of diseased adults and spread of HIV infection, the infection rates in children are likely to increase. It is estimated that in developing countries the annual risk of tuberculosis infection in children is 2.5%. Nearly 8-20% of the deaths caused by tuberculosis occur in children. Lymph node tuberculosis has increased over last two decades. HIV infected children are at an increased risk of tuberculosis, particularly disseminated disease. In last two decades drug resistant tuberculosis has increased gradually. The rates of drug resistance to any drug varied from 20% to 80% in different geographic regions. Various diagnostic techniques such as improved culture techniques, serodiagnosis, and nucleic acid amplification have been developed and evaluated to improve diagnosis of childhood tuberculosis. Serodiagnosis is an attractive investigation but till date none of the tests have desirable sensitivity and specificity. Tests based on nucleic acid amplification are a promising advance. Relatively less experience in children, need for technical expertise and high cost are limiting factors for their use in children with tuberculosis. Short-course chemotherapy for childhood tuberculosis is well established. Treatment with intermittent regimens is comparable to daily regimens. Directly observed treatment strategy have shown encouraging result.

BCG Vaccine↗
PubMed1991

[Whipple's disease and tuberculosis. A previously unreported association].

Whipple's disease and pulmonary and lymph node tuberculosis have been diagnosed in a 70 year-old man hospitalized for weight loss and fever. The tuberculous or Whipple's disease-related nature of associated non-necrotizing epithelioid hepatic granulomas could not be determined. The existence of cellular immune defects in Whipple's disease could explain the association with tuberculosis, which has not been previously reported in the literature.

Aged↗
PubMedDate not supplied

Tuberculous lymphadenitis in Afghan refugees.

BACKGROUND: Tuberculosis is a disease of poor countries. The war-stricken Afghan refugees, owing to abject poverty, illiteracy, lack of social awareness and poor hygienic conditions, are highly susceptible to tuberculosis. This study was conducted to assess the frequency of peripheral lymph node tuberculosis in Afghan refugees. METHODS: One thousand lymph node biopsies from Afghan refugees were examined histopathologically. The diagnosis was undertaken on morphological grounds. Lymph nodes containing caseating epithelioid cell granulomas were identified as tuberculous. Age and sex of the patient and site of biopsy were also recorded. RESULTS: Sixty nine percent of the nodes revealed tuberculosis. Male:Female ratio was 1:1.2. Of all the cases 72% cases were 10-30 years of age. The most common site involved was neck that was involved in 79% of cases. CONCLUSIONS: Tuberculous lymphadenitis has an alarmingly high prevalence in Afghan refugees of NWFP.

Adolescent↗