[Toothpastes with agents which reduce formation of plaque and calculus].
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Earlier studies showed that an antibacterial lactoperoxydase system in the saliva is activated by the application of a hydrogen paroxide-generating combination of enzymes: amyloglucosidase and glucose oxydase. The object of the present study was to investigate the effect of these enzymes in a test and control group of 29 subjects. The results showed the plaque-inhibiting effect of the enzyme paste. An influence on the gingiva could not be demonstrated.
After 7 years of use of a Na2FPO3 paste, the reduction of DMF surfaces was reduced by 36-38%, relating to the control group. The caries inhibiting effect is statistically ensured. Separate consideration of the first molar shows a caries reduction of 40-42%.
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On subdiving the patients into age-groups, it was found that the relative improvement in the 46--55 year-old patients amounted only to 18% as compared to nearly 27% in patients of age-groups in which hormonal influences are likely to occur. The sex-linked differences in the periodontal condition became evident by higher initial values for the inflammatory component and a low relative improvement (25.53%) in women than in men (28.25%). The relative improvement in smokers (43.49%) as compared to that in non-smokers (23.01%) demonstrated the beneficial effect of benzylnicotinate on the nicotine-induced vasoconstriction.
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