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Unlocking the brain: attempts to improve mental function of microcephalic retarded children by "craniotomy".

"Is it sufficient glory to don a white apron and swing a carbolized knife and is therein a sufficient indication to let daylight into a deformed cranium and on top of a hopelessly defective brain, and to proclaim success because the victim consented not to die of the assault? Such rash feats of indiscriminate surgery, if continued, moreover in the presence of fourteen deaths in thirty-three cases, are stains on your hands and sins on your souls. No ocean of soap and water will cleanse those hands, no power of corrosive sublimate will disinfect the souls." These passionate words, delivered by Abraham Jacobi, the father of American pediatrics, at the International Congress in Rome in 1893, and later in the article "Non nocere" (42), epitomize the growing antagonism to the attempts by many prominent surgeons to improve the gloomy fate of severely retarded, microcephalic children by "liberating" their brains from their presumed bony chains by "linear craniotomy." This article portrays how the fallacious 19th-century concepts of the relationship between the capacity of the cranial cavity and intelligence, backed by "scientific racism" together with the changing attitude toward retarded and malformed children, generated a surgical solution for microcephalic idiocy. It describes how hopeful surgeons, neurologists, and pediatricians, encouraged by the advances in anesthesia and asepsis, lost their judgment and disregarded logic and evidence. They generated a wave of enthusiasm and hope that soared from the United States and France through the British Isles, Europe, and as far as Ceylon and Australia to end in a ripple of bitter disgrace under caustic criticism, leaving a scar on the recently budding field of neurological surgery.

Child↗

Yoruba customs and beliefs pertaining to twins.

The Yoruba are an important ethnic group mainly occupying Southwestern Nigeria. Mainly for genetic reasons, this very large tribe happens to present the highest dizygotic twinning rate in the world (4.4 % of all maternities). The high perinatal mortality rate associated with such pregnancies has contributed to the integration of a special twin belief system within the African traditional religion of this tribe. The latter is based on the concept of a supreme deity called Olodumare or Olorun, assisted by a series of secondary gods (Orisha) while Yoruba religion also involves immortality and reincarnation of the soul based on the animistic cult of ancestors. Twins are therefore given special names and believed to detain special preternatural powers. In keeping with their refined artistic tradition, the Yoruba have produced numerous wooden statuettes called Ibejis that represent the souls of deceased newborn twins and are involved in elaborate rituals. Among Yoruba traditional beliefs and lore some twin-related themes are represented which are also found in other parts of the world. Basic features of the original Yoruba beliefs have found their way into the religious traditions of descendants of African slaves imported in the West Indies and in South America.

Black or African American↗

[The concept of intensity in Charles Bonnet's psychology].

The concepts of intensity and vivacity are studied in the psychological texts of Charles Bonnet (1720-1793). In 1854, intensity measured physical movements of the nerves, and vivacity pertained to psychical order. In 1760, however, the two scales were confused. This development, based on an imaginary of measure justified by methodological considerations, led to a research field whose apparent goal was to measure the soul's faculties. Moreover, intensity--which had been quantified in Bouguer's work at that time (1760)--was abandoned and was transferred to the notion of energy, not yet quantified. Consequently, Bonnet's apparent dualism seems, in fact, to have been grounded on a monistic foundation, assuring an unmeasurable place to the soul, corresponding to freedom.

Biophysics↗

Personal time: the patient's experience.

When a life-threatening or chronic disease is diagnosed, patients may find that their sense of time, the passage of days, and their view of the future are altered. Most of the time, people live in a sense of linear time, or kronos. When illness strikes, they may begin to spend more time in kairos, a sense of soul-satisfying time, such as the feeling one gets when walking on the seashore with a grandchild, working in the garden, or talking with friends over good food and wine. This article comments on two patients, one who explores kairos through a diary that documents her positive attitude toward coping with multiple sclerosis, and one, a young artist with Hodgkin disease, who explores his condition through 96 paintings of his experience of the disease. Rather than "the devouring tyrant of linear time," life can be seen in a circular fashion, the eternal braid of Hofstadter. Patients begin to see life more in terms of cycles of daily events, routines, and the change of seasons. Illness brings one "close to the bone" of the soul's needs, with a reappraisal of the journey of life as a continuous line, to life spread out on a landscape that includes the past and the future.

Anecdotes as Topic↗

[The image of Man and his care in the hygiene-dietetic tratises of the XVII and XVIII centuries].

This work presents a study of the traditional hygienc-dietetic treatises of the XVII and XVIII centuries. Two characteristics define these treatises: the following of Aristotelian and Galenic postulates in their theoretical conception and, in the practical section, the preponderance of the care of the soul in relation to that of the body. This work firstly cover their theoretical foundation (the vision of Man derived from their conception of the body, their notion of the soul and the dynamic relationship established between both); and, secondly, the practical application derived from these concepts (the care of Man on both his planes; the corporal and the psychic).

Diet↗

[Dietetics and the health and fitness cult. The risks of dietetics in the Welfare State].

We shall analyse the reasons why various matters related to diet have become a type of a purification ritual in the welfare society. In order to explain this circumstance three historic moments in the use of diet shall be studied: a) Diet as an explicit means in the care of the soul. Besides its function in the care of the body, diet was used in ancient times as a specific remedy to improve both the psychic and moral aspects of the mental faculties. b) Diet as an implicit remedy in moral well-being. From the Renaissance onwards diet no longer had this explicit function in curing the soul, however it tacitly retained a certain effect on the moral factors. c) Diet as an instrument of the health and fitness cult. Despite the scientific configuration of dietetics in the second half of the nineteenth century, old function of diet remained mutatis mutandis with regards to the moral sphere of the subject. Factors such as the development of how thinness or fatness was viewed at this time and the resulting explosion of interest in controlling body-weight, which acquired characteristics of pseudo-religious activity, may explain this fact. In this way the old idea of "you are what you eat" coexists with the more modern one of "you eat what you are".

Diet Fads↗

[Death according to old-Israeli beliefs].

In Palestine the Neanderthal men and fossil contemporary men treated the dead kinsmen in a special way which can be observed in his intentional burials. They are the evidence of the belief in life after death that probably was imagined as a continuation of earthly life. In the Bible thanatology issues do not assume the crucial importance; the descriptions of dying and posthumous continuance of a man are brief and subject to a certain development. Death is not glorified, the dead cult is forbidden, the corps are treated in a ritual context as impure objects, contaminating people and environment. Death was not considered as boundary, temporary phenomen but as a gradual outflow of life. Only in the later fragments of the Old Testament there appears the concept that in death there takes place the ultimate separation between two constituent elements of a man i.e. between body that turns into dust and soul that goes back to God. The Bible distinguishes various types of death and its causes; but it is God who is the ultimate master of life and death. The other life is considered to be a manifestation of God's blessing. The Holy Scriptures pays special attention to the words spoken by the dying man, occasionally ascribing a prophetic sense to them. Although the funeral ceremony was not ostentatious it was most of the time excessive. The funeral was organized immediately after death, usually after 8 hours and the same day if it was possible. The corpse was wrapped up in linen and buried in hewn in the rock caves or terrestrial graves; bodies were neither burnt nor mummified. "Weeping" and mourning for the deceased lasted quite short - 7 days, seldom longer. Any forms of communicating with the soul of the dead person were severely forbidden and prosecuted; they were considered as discordant with the Jahweh cult. Some of the texts seem to reveal personification of death; it is never considered, however, as a being or power independent of God.

Attitude to Death↗

[A world tailored for children and the young. The children and the young around us and the child and the adolescent within each of us].

UNLABELLED: Towards the end of the nineteenth century in America, a court that normally dealt with animal abuse found itself facing a very special problem: it had to discuss for the very first time a case of child abuse. It might seem a paradox to many that a matter of this nature should be discussed in a court set up for a quite different purpose, but it was not an error arising out of the lack of room in the civil court nor an error of competency: it happened to be the only place judged to be appropriate to discuss the rights of a child, mistreatment of whom was handled on a par with abuse of animals. In spite of the section expressly dedicated to children in the Universal Declaration of Human Rights of 1789, the world had to wait for the Geneva Convention of 1924 before the first declaration of children's rights was promulgated. There were five main principles: the right to a healthy psychophysical development, the right to be nourished, cared for, returned to a normal life if demoralised, looked after and aided in the case of orphans. But only with the international Convention of children's rights of New York in 1989 was it possible to draft a text for the full, more comprehensive protection of infancy, two centuries after the first pronouncement on the occasion of the universal declaration of human rights. Two centuries of struggles and growing awareness of the problem of children (and at the same time of women and mothers) in the world, two centuries that have produced all over the world the complete idea of the child as having rights and being an active part of contemporary society. But the examination of the current situation brings us to the main problem: if a virtuous circle is not established between rights, infant culture and duties of adults, then the declarations of this century will have to wait many years more before becoming a practical part of our society. What then should be done to make sure that the declarations and conventions on rights do not remain a mere expression of principles? There can be no evolution in children's living conditions, nor protection of their rights, if we do not create a culture of infancy based on two premises: the rights of children and the duties of adults with respect to children. Today an exact and comprehensive knowledge of the rights of children is necessary above all starting with their right to freedom, experience, opinion, equal opportunity for development and education, defence against all types of abuse, and their right to a family. But at the same time it is necessary to act in the area of the duties of parents and adults: the question is one of building up a cultural system that includes the rights whereby the prerogatives of children are matched with corresponding duties of adults, a culture of values that responsibilises adults by way of a process of personal awareness and parent training. The adult must find himself personally in harmony in his relationship with life so as not to compromise on child training: the idea of a vulnerable future must be avoided; a future that is insecure and defenceless for children and adolescents who are future adults. A third factor must cater for this, namely modern society whose task it is to build structures (interconnected by means of an interdisciplinary project and through the possibility that modern technology also offers them) to supply opportunities and laws that favour and protect the personality of both child and adult. In this case considerable value would be taken on by the drafting of a "Charter of Duties of adults with respect to children and adolescents" that favours the birth of new standards and national and international conventions aimed at a new conception of society understood as a set of several parts, children, adolescents, adults, each subject of rights. By this approach the commitment of individual associations, organisations and institutions would start a process of social development which as of today is the last and on]y real revolution possible to improve the conditions of life of the person as such, and not the person as such, and not only of the person as a citizen of one nation or another. IN CONCLUSION: no development is possible if we do not take steps as an international community to protect the first citizens of the world who are and always will bc children. 1n this sense, psychoanimation, which is a psychopedagogic-cultural intervention methodology based on a holistic approach and employs cognitive, creative, corporeal techniques to foster, in the individual and in the group, that ''growth'', that "awareness'', that "responsibility'' which have their "roots'' in self-awareness and in the possibility of acquiring cultural instruments that are scientifically and humanistically suitable to ''act'' individually and collectively, the "change'' in human societies sets itself the diffusion of a Culture of Infancy and of Adolescence as an objective. In fact for Psychoanimation that means: (''give soul to the soul'' employing all languages in interdisciplinary fashion for communication and social integration) in order to authentically permit knowledge, communication and exchange among human beings) the last ''possible revolution" is that connected with the success, all over the world, of a Culture of Infancy and of Adolescence. What is the possibility that this converts into: ''a world made to the measure of children'': the children around us and the chi]d within us!

Adolescent↗

Messy conversations and the willingness to be disturbed.

We all long for a sense of community in our professional lives where we can bring our spirit, passion, and whole selves to work. When we work in environments of tribal warfare and clans carrying out subversive activities, we will choose to leave our souls at home to protect them from the toxicity of the work environment. For anyone who has been cared for by nurses who have left their soul at home, you have experienced the outcome of negative environments that cannot have effective conversations. Recently a nurse told about her experience of realizing one day that she had the right to be happy at work so that she could more effectively take care of her 5-year-old daughter when she returned home. When she saw this as a right, she made a decision to leave her organization and look for a place that valued conversations and harmony rather than aggression and lack of trust. The only way to improve the world is through relationships, and conversations are the prelude to creating that change. Having the courage to reach out and start the dialogue knowing full well that it might be very messy is the only way to end the fragmentation and loss of community we experience in our organizations. Wheatley (2002) describes the experience of "...sacred as a feeling that I belong here" (p. 133). In the process of conversations, we can explore and appreciate our differences but also feel more connected and one with each other as a result of having the courage to converse. When we see each other as equals, we also free ourselves to open up to new learning and relationships which can lead to excellence in clinical outcomes. It's all about the courage of conversations.$

Attitude of Health Personnel↗

The leader's challenge: meetings, spiritual energy, and sneaker ratio.

Leaders who inspire are affirming to everyone in the meeting. They create the environment that meets the needs of the people first, not the leaders. People yearn to be heard, and to be engaged with their soul in genuine dialogue and engagement. If that doesn't happen in the meeting, then they search for meaning and support of their soul elsewhere and sneaker time increases. Leaders get from people what they give to them. If people in a meeting are given nothing, they in turn have nothing to give. If they truly feel they are served by the leader, they will give back much more than they receive. As Martin Luther King, Jr. so aptly said: "Everyone can be great because everyone can serve.

Communication↗

[Early Greek medicine and Plato's cosmology].

The purpose of this paper is to show the influence of Early greek medicine on Plato's Cosmology. Alcmaeon holds that health depends on proportion (equality; isonomia) or proportioned mixture of opposing factors. This notion dominated nearly all greek medicine, and also influenced Plato's cosmology greatly. Generally each greek doctors believed that man consisted of opposing factors, though these are designated differently. Alcmaeon takes powers - hot and dry, cold and hot, vitter, sweet and the rest as those factors. On the other hand, Philistion of Locri adopts the four element theory of Empedocles. He conceives that human body as a mixture of the four elements, and health consists in proportion of these opposing four element, basically as Alcmaeon. This notion is accepted by Plato. Only Plato differs from Philistion in that he doesn't consider the four elements as the ultimate factors. In Timaeus Plato explain that the Demiourgos constructed the four elements through introducing 'proportion' into the primitive materials (the oppositives) by means of shapes and numbers. And Plato thinks that the cosmic body and soul was constructed basically in the same way as the four elements. This is true of the human body and soul. Also Plato explicates diseases from standpoint of proportion or symmetry. Moreover according to Philebus, the good states (i.e. 'health', 'music', 'season' etc) in the cosmos arises out of the right mixture of the limit and the unlimited. In the other word this mixture is proportioned mixture of the oppositives by aid of ratios. In short Plato believes that both the cosmos itself and the good states s proportioned mixture of the oppositives. Thus Plato' cosmology is fundamentally based upon Alcmaeon's or Philistion's concept of Health.

Greece, Ancient↗

[Descartes and medicine].

The French philosopher and mathematician René Descartes (1596-1650) gave a high priority to medicine and dedicated a great deal of his life to medical studies. Nevertheless his relation to medicine has always been much discussed. However, a number of recent works have contributed to reassessing the earlier critique which nearly wrote him out from medical history. The recent biographical dismissal of a number of earlier allegations and the recent interpretations of the medical contents of his collected writings ought to result in Descartes' reinstatement in medical history. His novel anti-Aristotelian methodology had a crucial influence on the medicine of the subsequent decades. Also his early defense of Harvey's theory of blood circulation had great influence. Especially his thoughts about a mechanical physiology by means of which the functions of the body could be explained without involvement of "occult faculties" influenced that time. His empirical mistakes, including the central role which he ascribed to the corpus pineale, are offset, which already Steno noted, by his brilliant thoughts about the function and importance of the brain. Although he did not make any really new empirical discoveries within medicine, he advanced a number of concrete ideas which later lead to actual discoveries such as visual accommodation, the reflex concept and the reciprocal innervations of antagonistic muscles. Descartes' psychosomatic view of the importance of the interplay between sensations, "the passions of the soul", and the free will in the preservation of health shows in addition that his fundamental soul-body dualism was far more nuanced than is often claimed.

Historiography↗

What is in a name? Professionals and service users' opinions of the Hebrew terms used to name psychiatric disorders and disability.

OBJECTIVES: Stigma constitutes the hidden burden of mental disorders. Its ubiquitous presence may be reinforced by iatrogenic factors, such as the terms used to name mental disorders and disability. This preliminary study examines opinions with regard to the use of these terms in Hebrew. METHODS: Two samples of convenience, mental health professionals (n=330) and service users (n=75), were asked to complete a self-administered questionnaire about their respective acceptance of the current term in use to name psychiatric disorders and disability, as well as their preference for alternative terms that may carry a lesser degree of stigma. The distribution of responses was compared within and between these two groups. RESULTS: There was consensus in both groups that a substantial proportion of service users reject the current term used to name mental disorder, mahalat nefesh (disease of the soul). Mental health professionals had a statistically significant acceptance of this term compared to service users. The term hafra'a nafshit (disorder of the soul) was reported to carry a lesser degree of stigma. No specific term was selected by more than a third of the respondents to best define disability resulting from a psychiatric disorder. CONCLUSION: A case for study and possible subsequent action was established by this pilot inquiry.

Attitude of Health Personnel↗

[The life of medical historian Miki Sakae, and the "history of Korean medicine and of diseases in Korea"].

Miki Sakae was a Medical historian, who is well known for his studies of Korean medicine. He authored the renowned trilogy which dealt with subjects of Korean medicine and diseases, namely the "History of Korean Medicine and of Diseases in Korea", "Bibliography of Korean Medical Books", and "The Chronological Table of Medical Events in Korea"), during the Japanese Occupation period. He was born in 1903 in Osaka, Japan, and graduated from the Kyushu College of Medicine. In 1928 he was assigned to the Gyeongseong Imperial University's College of Medicine as a professor, and also served as Chief of the Suweon Provincial Hospital while he was staying in Korea. During the 18-year period of his stay, he widely collected medical books of Korea and also thoroughly studied them. He returned to Japan in 1944 due to the illness of his father, but continued his studies of Korean medicine, and in 1955 published the "History of Korean Medicine and of Diseases in Korea" for the first time. Following such accomplishment, "Bibliography of Korean Medical Books" was published in 1956, the next year, and finally "The Chronological Table of Medical Events in Korea" was published a few decades later, in 1985. Since the 1950s, aside of continuing to study and author the history of Korean medicine, he had also engaged himself in a joint effort associated with the members of the Medical History Association of Japan (which also included the alumni of the Kyushu College of Medicine) in a group study of Huseya Soteki, the first Japanese Experimental Physiologist. He also attempted at establishing an academic branch which could be referred to as Experimental Historical Studies of Medicine, by recreating the experiments of Huseya Soteki with his own son. Later he also expanded his interest and studies to the medical history of the world and also the area of Medical Ethics. But his ultimate interest and passion were always targeted at the Medicine of Korea, and the one consistent position he maintained during his entire life regarding the Korean medicine, was that 'One can only talk about the medicine of China and Japan when he or she is well versed in the medicine of Korea'. And his lifetime achievement, "History of Korean Medicine and of Diseases in Korea" was authored upon the basis established by such conviction and philosophy. First, in this book the perspective of Cultural Transmission, which considers the flow of cultural qualities and assets to be ordinarily flowing from highly developed regions to less developed ones, was firmly maintained. He argued that the medicine of China had to pass through the Korean peninsula to reach Japan. Second, he suggested that studies of medicine and diseases could only be fully and thoroughly understood when it is approached not only from the perspective devised by medical historical studies but also from perspectives devised for general and total historical examination of human life events. And third, he argued that all historical studies should be based upon proofs and evidences, and the 'development' factor of a particular type of studies or practices should be measured by whether that study or practice has reached or accomplished the level of Western modern science. Demonstrating such conviction, out of Korean traditional medical practices he particularly examined the medical procedures of treating tumors or regulations and procedures developed for forensic medicine, which he considered superior to or at least at the same level with Western medicine. In his final years he was forced to battle cancer, but he refused to be hospitalized. Instead, he exhibited his firm belief that medicine and medical practices which believe in the ultimate power of human body and soul are what the practitioners should pursue in order to acquire the very core of medicine. He died in 1992, at home, surrounded by his family. He is known to have always uttered that one of the most celebrated Medical books of Korea, the "Dongeui Bogam" authored by Heo Jun, was a true example of a book containing 'Medicine Based upon Human Body and Soul'. A huge portrait of Heo Jun is reported to have been hung at the living room of his house all the time.

Historiography↗

In vitro growth characteristics of virally transformed murine myeloid cells.

Bone marrow from normal BALB/c mice, mice with myeloid leukemia induced by Soule myeloid leukemia virus, and mice with virally induced mammary carcinoma was cultured in semisolid agar. Bone marrow from either leukemic or mammary tumor-bearing mice produces more clones in vitro in the presence of a specific colony-stimulating factor. However, in all cases, the myeloid progenitor cells have similar requirements for the colony-stimulating factor. The optimum condition for growth in all instances is 7% fetal calf serum + 7% horse serum + 7% tryptose phosphate broth. Decrease in the concentration of these three constituents has a less drastic effect on in vitro proliferation of bone marrow cells from leukemic mice. Some cells from Soule virus-induced leukemias even grew in the absence of serum. The combination of suboptimal amounts of serum and colony-stimulating factor is used as a tool for detecting cells with altered growth characteristics in bone marrow of leukemic mice. During the progression of the leukemia, there is an increase in the amount of transformed colony-forming cells per 5 X 10(4) bone marrow cells. The increase is already noticeable 4 weeks after inoculation, when no clinical signs of the leukemia are present, and reaches a maximum of about 20%.

Animals↗

The rights of humans and other animals.

Animals have occupied a precarious, often changing position in the major moral traditions of Western thought. Viewed as reincarnations of human souls in Eastern thought, they have been denied not only souls but awareness in others. And while some theories argue that we have duties directly to sentient animals, others maintain that all our duties involving these animals are indirect duties to humanity. The implications of these approaches for animal experimentation will be explained, as will the fundamental difference between the philosophy of animal rights, on the one hand, and these traditional approaches, on the other. That philosophy is categorically abolitionist in its implications concerning the harmful use of animals in science, whereas the traditional approaches are reformist at best.

Animal Testing Alternatives↗

[Theoretical concepts of modern pathology (a critique of their medical philosophical foundations)].

Separation of theoretical pathology into an independent branch of science seems to be justified and creation of the Centre of Theoretical pathology in the Heidelberg Academy of Sciences is due and useful. As W. Doerr truly states, the theoretical pathology seems to be over the pathological physiology and general pathology, exerts additional functions, studies questions of the methodology in pathology, defines more exactly and analyzes the notion of disease, other concepts and terms, clarifies early preclinical and clinical disease manifestations, determines sociological and psychological factors of disease. However, we are not in full agreement with our colleagues from the FRG in the definition of "disease" and in the interpretation of such categories as "spirit", "soul", "psychic". K. Rotschuh' suggestion to consider the disease in terms of "body-soul" appears to be interesting but to be productive, it must be linked with the problems of medical psychology. W. Doerr and his colleagues support the dualistic concepts of human nature which is unacceptable for us; they claim that the understanding of the theoretical pathology essence is possible only on the basis of theleology and spirit (theology). As the highest commencenment on the way of the theoretical pathology recognition W. Doerr's categorical declaration that theoretical pathology based on the "gestalttheorie" returns scientists, as he writes" to their great delight, to the possibility of studying "spiritual essence of the disease". In W. Doerr's opinion, studying the concept of theoretical pathology "from the spiritual point of view" will ensure its brilliant future. Of course, we, Soviet pathologists and philosophers, do not reject the significance of the integrity theory in the meaning of the disease psycophysiological integrity, yet we decidedly reject any idealistic concepts. W. Doeer and his colleagues are right that the theoretical pathology stimulates the search of the approaches to the solution of complex biomedical problems, favours the creation of more precise definitions and terminology. Likewise, W. Doerr is right that he sharply condemns the attempts of some pathologists to substitute qualitative differences in pathological processes by quantitative ones; this may result, in his view, in one-sided erroneous conclusions.(ABSTRACT TRUNCATED AT 400 WORDS)

Communism↗

[Michael Servetus' physiology in the light of his anthropology].

This essay starts with a short description of the life and works of Michael Servetus. Then the part of the innovator the Spanish physician played in describing the minor circulation is being examined alongside the contributions made by other contemporary physicians who tried to explain this physiological process. The ideas of the philosophical anthropology of Servetus are represented with special stress of the fact that beyond the theological frame, in his main opus Christianismi restitutio there are typical characteristics from the Renaissance (i.e. ethic relativism etc.). At the end it becomes clear that the description of the minor circulation is only to serve the purpose of explaining Servetus's theological thesis according to which the seat of the soul is in the blood. He stipulates that the "sensible soul" is to be found in the choroidal plexus of the ventricles of the brain or else in the pineal gland. It is one of the merits of Servetus, too, that he had foreseen the capillaries (capillares) which he describes as well in the case of the lung vessels as in the case of the choroidal plexus in the brain. The last part deals with the history and background of the new edition of Christianismi restitutio, published 1790 in Nuremberg, which again is based on some recent archival research.

Anthropology↗