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[Bacterial flora in obstructed bile ducts].

The authors present the results of bile cultivation from obturated bile ducts. The bile was obtained during ERCP. The results agree in principle with data reported in the literature. The authors emphasize the regional variability of bacterial strains and their sensitivity. It is thus an ever urgent problem which deserves attention, in particular preventive administration of antibiotics. At the authors department as preventive antibiotic cefoperazone proved useful.

Bacteria↗

Effect of doxycycline on the apical seal of retrograde filling materials.

In this study, we examined the effect of doxycycline hydrochloride (DH) on the apical seal. Results indicated that teeth that were retrofilled with IRM or amalgam following doxycycline irrigation had significantly less dye penetration (p < 0.05). Due to its antimicrobial activity, smear layer removal ability, and improvement of apical seal, doxycycline solution may be used as an irrigant.

Analysis of Variance↗

[Mirizzi syndrome and its variants].

Between 1981 and 1987 5434 patients were studied by ERCP in Allgemeines Krankenhaus Hamburg-Barmbeck. 26 (i.e. 0.43%) suffered from Mirizze syndrome with the triad of cholelithiasis, cholecystitis and obstructive biliary disease. They were classified in four different types according to the variable localisation and origin of the biliary obstruction. 16 patients corresponded to the classical type (I and II) with compression, penetration, and obturation by the concrement, five patients matched borderline with infiltration (III) and five patients were classified as variants of this syndrome. A mild elevation of serum bilirubine and alkaline phosphatase indicated more likely the benign etiology of type I to III, however, a marked elevation of alkaline phosphatase in the variants suggested more likely a malignant underlying disease. The diagnosis was ascertained in all cases by ERC and sonography preoperatively and was verified by laparotomy (n = 18) and follow-up (n = 6).

Aged↗

CT signs of urethral injury.

Computed tomography (CT) is the accepted frontline imaging modality for blunt abdominopelvic trauma. However, urethral injuries are traditionally diagnosed with retrograde urethrography. The CT appearances of urethral injuries and the signs associated with posterior urethral injuries are not well described in the literature. CT scans of patients with pelvic fractures and urethrographically proved posterior urethral injuries were evaluated. CT scans of patients with similar pelvic fractures who did not have urethral injuries were also evaluated. The CT findings of elevation of the prostatic apex, extravasation of urinary tract contrast material above the urogenital diaphragm (UGD), and extravasation of urinary tract contrast material below the UGD were specific for type I, II, and III urethral injuries, respectively. If extraperitoneal bladder rupture is present along with periurethral extravasation of contrast material, the possibility of type IV and IVA urethral injuries should be considered. In addition, the CT findings of distortion or obscuration of the UGD fat plane, hematoma of the ischiocavernosus muscle, distortion or obscuration of the prostatic contour, distortion or obscuration of the bulbocavernosus muscle, and hematoma of the obturator internus muscle were more common in patients with pelvic fractures and associated urethral injuries than in patients with uncomplicated pelvic fractures.

Humans↗

[Retrograde root canal filling using resin and a dentin bonding agent: operative procedures].

Using a specially designed filled resin and the bonding agent Gluma, the aims were to obtain a thin retrograde filling covering the slightly concave root surface which would close all root canals and avoid excess filling material. To achieve a strong bond, the resin must be applied to an absolutely dry Gluma surface, free of all traces of blood or saliva. Hemostasis was obtained primarily by applying 1% adrenalin and by use of a needle suction tip. Absence of moisture was obtained by removing all soft tissues from the cavity, using dry compressed air and avoiding condensed moisture from a cool resin. To avoid loosening of the filling, the working time of the resin must not be exceeded, and removal of excess filling material must not be done before polymerization is complete. Contamination of the various chemicals and filled resin must be avoided in order to avoid damage to the surrounding tissues.

Aldehydes↗

[Retrograde root canal filling using resin and a dentin bonding agent: analysis of failures].

With Gluma, an aqueous solution of 5% glutaraldehyde and 35% HE-MA, resin may be chemically bonded to a root surface. In the article failures of apical retrograde root fillings with Gluma and resin (retroplast) were studied, clinically and radiographically, as well as by microscopy of ground sections of extracted teeth or by scanning electron microscopy of loosened retroplast fillings. Out of 52 failures, 23 were not related to retroplast (18 had root fracture). Of the remaining 29 cases, 26 were reoperated. More than half of the failures had loose retroplast fillings. The loosening could be caused by: exceeded working time for the resin or moisture, blood or saliva present on the root before filling, debris on the root surface, possibly because of corrosion, or the presence of phenol in the root canal. In five cases of failure there were denuded root canals. Four cases (of 800) with rapidly developing osteitis might have been due to contamination of bone and soft tissue by EDTA, non-polymerized resin, alcohol or glutaraldehyde.

Aldehydes↗

[Are Ag-points, gutta percha and amalgam still applicable for apical sealing?].

Nowadays Ag-points, gutta percha and amalgam are widely used as orthograde or retrograde root-filling materials. The biocompatibility of these materials however remains debatable. Ag-points are easy to manipulate and when used together with an appropriate cement, offer an adequate seal. Yet an important disadvantage is the susceptibility to corrosion resulting in argyrosis and inflammatory reaction. Tissue cultures proved these corrosion by products to be highly cytotoxic. Other investigations, reported that the inflammatory tissue response seen with gutta percha, may be due to small amounts of additives included in gutta percha. Equally, there is no unanimity concerning the biocompatibility of amalgam, and the extent of corrosion and inflammatory reaction is possibly related to the composition of the amalgam used. Nevertheless in vivo studies demonstrated that, when freshly mixed amalgam, gutta percha or Ag-points are implanted in the femur of rats, mature bone was formed in direct contact with these materials.

Animals↗