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Results for “MANDIBULAR CONDYLE”

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At least 757 records · Page 42Linked to original sources
PubMed2005

Expression of Notch1 and Math1 in mandibular condyle cartilage in neonatal mice.

On the basis of the cellular morphological changes in the cartilaginous area, the mandibular condylar cartilage is histopathologically composed of four different cell layers--fibrous, proliferative, maturative, and hypertrophic. Reaction for Notch1 was present in the hypertrophic cells only. However, Math1 was locally distributed in the hypertrophic layer and partially in the proliferative layer. The expression patterns of Notch1 and Math1 were slightly different. These results suggest that the morphogenesis regulation factors of Notch1 and Math1 may play some role in mandibular condylar cartilage. Positive reactions to osteopontin, as a control, were detected in the cytoplasm of all layers, although they varied from published data.

Animals↗
PubMed1988

Biochemical and autoradiographical evidence that anterior mandibular displacement in the young growing rat does not stimulate cell proliferation or matrix formation at the mandibular condyle.

A removable bite plate was used to induce forward mandibular displacement in four-week-old rats for 10 h/day for 1, 3, 7, 11 and 14 days. The animals were killed and the condylar explants pulsed in vitro for 6 h with either [3H]-thymidine or [3H]-proline or 35SO(2-)4. The specific activity of radio-isotope incorporation was expressed as dis/min per microgram DNA, dis/min per mg protein and dis/min per microgram sulphated glycosaminoglycans (GAG). [3H]-thymidine autoradiography was also used in a 14-day experiment to establish a radioactive index (labelled cells per 1000 cells counted) for the anterior, middle and posterior regions of the condyle. There was no significant alteration in either cell proliferation (dis/min per microgram DNA and radioactive index) or matrix formation (dis/min per mg protein and dis/min per microgram GAG) at any point in the time scale.

Animals↗
PubMed1988

Accuracy of the oblique lateral transcranial projection, lateral tomography, and x-ray stereometry in evaluation of mandibular condyle displacement.

Condylar displacement similar to that occurring during and after mandibular ramus osteotomies was simulated in an in vitro study. Three different radiographic methods were used to measure the displacement, and the accuracy of the methods was compared. The stereometric method was more accurate than the plain radiographic methods and permitted measurements in all three dimensions. The oblique lateral transcranial projection was more accurate than lateral tomography, possibly because identification of measurement points in lateral tomography was complicated by the substantial displacement of the condyle.

Craniotomy↗
PubMedDate not supplied

Parosteal chondrosarcoma, a very rare condition of the mandibular condyle.

We present a rare case of parosteal chondrosarcoma of the madibular condyle. The patient was referred for a functional limitation of the left temporo-mandibular joint. CT and MRI examinations demonstrated a 3.5-cm cystic mass with a peripheral rim of contrast enhancement located in the left pterygo-maxillary space. The mass had partial intraarticular spread causing deformation and focal cortical erosion of the medial aspect of the condylar head. The lesion was surgically removed; the histological diagnosis was of low-grade chondrosarcoma.

Bone Neoplasms↗
PubMed2000

Distribution and characterization of proliferative cells in the rat mandibular condyle during growth.

Distribution of proliferative cells and localization of types I and II collagen were examined in the rat mandibular condylar cartilage of 36 long-Evans/Turku strain rats during normal postnatal growth using an immunohistochemical method combined with histomorphometry. There were considerable differences in the thickness of the proliferative cell layer in the condylar head, with most mitoses occurring in the postero-superior area. It was found that the extracellular matrix of the proliferative cells does not stain for type II collagen in 20-day-old and older rats, and that besides the subchondral bone, the strongest intensity for type I collagen stain was always localized in the articular surface of the condylar head. Statistically significant overlapping of the proliferative cell layer and the one secreting type II collagen occurred during the earlier stages of development, particularly in the postero-superior area of the condylar head. As type II collagen is considered to be a marker for identification of typical cartilage cells, the findings indicate that, in addition to undifferentiated cells, a portion of the proliferative cells can be characterized as chondroblasts during the early postnatal period in rats, but not in the later stages of development. The developmental phase of the condylar cartilage should therefore be taken into consideration when the effect of various biomechanical and humoral/hormonal factors on growth of the condylar cartilage is examined.

Animals↗
PubMed1986

The effect of prenatally increased oxygen tension on the development of the mandibular condyle.

Twenty-four Long Evans/Turku rats were used to study the effect of prenatally increased oxygen tension on the mandibular condylar cartilage. Pregnant rats were exposed to increased oxygen tension in an air chamber for 14 days. The animals were returned to normal laboratory conditions after parturition. Three control and three experimental young rats were killed at the ages of 1, 5, 10, and 20 days for microscopic studies. Sagittal sections of the temporomandibular joint showed the cartilagenous condylar process to be narrower anteroposteriorly at 1, 5, 10, and 20 days postnatally, and it seemed to be bent backwards in experimental animals at the age of 1 day, in comparison with controls. The mesenchymal and chondroblast cell layers were thickened at the ages of 1, 5, 10, and 20 days. The findings indicate that prenatally increased oxygen tension increases the postnatal mesenchymal cell population and support the hypothesis that the size of the mandible is partly determined by the number of mesenchymal cells present during the prenatal phase.

Animals↗