Ossicular replacement prosthesis. Clinical notes.
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Adult↗
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Results for “Gelatin Sponge, Absorbable”
Search indexed PubMed citations on genomics, clinical trials, systematic reviews and public health. Explore titles, authors and supplied subject terms, then open the PubMed record.
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Comparison of wire-vein and wire-gelfoam prostheses in stapedectomy for otosclerosis.
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Audiometry↗
Preoperative embolization of juvenile angiofibromas of the nasopharynx.
The juvenile nasopharyngeal angiofibroma is a vascular tumor. Careful and complete removal is challenging because of the brisk bleeding during surgery. The means applied to reduce this blood loss have included preoperative estrogens, ligation of feeding vessels, silicone embolization of feeding vessels, and cryosurgery. We have used preoperative Gelfoam embolization of the internal maxillary artery in seven patients. Our clinical impression of significant reduction in loss of blood was confirmed by comparison with 16 previous patients. The average amount of blood lost in the embolized group was half that of the control group. A study of this type comprises many variables; however, the results do suggest that preoperative embolization of the internal maxillary artery is of advantage in the surgical treatment of juvenile angiofibromas.
Adolescent↗
Cochlear implant revision: effects of reimplantation on the cochlea.
The removal of an indwelling cochlear implant electrode followed by reinsertion of a new device has been a maneuver of uncertain consequences to the cochlea and its surviving neural population. The present study was conducted in an attempt to elucidate the factors that determine whether a reimplantation procedure will be successful. Cochlear implantation followed by explantation and subsequent reimplantation was performed in eight adult cats. Evaluation of cochlear histopathology suggested a significant increase in electrode insertion trauma when there was proliferation of granulation tissue in the round window area and scala tympani. In other cases, atraumatic reinsertion was achieved without apparent injury to the cochlea. The results of a survey of cochlear implant manufacturers and surgeons indicate that electrode replacement can usually be accomplished without adverse effects. Difficulties have been encountered, however, in removing implants with protuberant electrodes and when reimplantation was attempted on a delayed basis following explantation.
Acute Disease↗
Middle ear gas generation in myringoplasties.
No Gelfoam was used to support the vein in 10 simple underlay vein graft myringoplasties. Computed tomographic studies 24 hours postoperatively showed gas filling 75% to 100% of the middle ears in three ears. The epitympanum and mastoid were also evaluated. Apparently, in some ears the middle ear generates gas in the immediate postoperative period to support fresh vein grafts.
Blood Vessel Prosthesis↗
Vascular effects of sustained-release fibroblast growth factors.
Since the half-life of most angiogenic growth factors is several hours or less, sustained-release delivery would be optimal for their future clinical use. Two fibroblast growth factors, basic fibroblast growth factor (bFGF) and endothelial cell growth factor (ECGF), were delivered in two sustained-released modalities (poloxamer 407 and a gelatin sponge [Gelfoam]) to attempt to increase soft tissue vascularity. In vitro bioactivity of ECGF-poloxamer formulations was also tested on endothelial cell cultures. Among vascular-compromised skin flaps in rabbits, ECGF-poloxamer (N = 26), bFGF-poloxamer (N = 5), ECGF-poloxamer (N = 9, irradiated), and bFGF-Gelfoam flaps (N = 22) did not demonstrate significant differences in viability and vascularity compared to controls (p > .05). Irradiation had a detrimental effect on both flap vascularity and viability (p = .02). Future efforts for sustained delivery of angiogenic proteins are critical in order to make them clinically useful in wound healing.
Animals↗
Intentional replantation of teeth in dogs and monkeys.
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Alveolar Process↗
Control of tubercular haemoptysis by bronchial artery embolization.
Thirty-seven patients presenting with massive or recurrent haemoptysis secondary to tuberculous aetiology were subjected to bronchial artery angiography. Of these, failure, to catheterize the bleeding vessel occurred in two patients while embolization was withheld in two patients due to the presence of anterior spinal artery arising from a common intercosto-bronchial trunk. Immediate arrest of bleeding was performed in the remaining 33 patients by selective embolization of the abnormal bronchial arteries with a resorbable material (Gelfoam). Regular follow up for a duration of 6 months after the procedure revealed relapse of haemoptysis in four patients; three were treated by re-embolization of the abnormal bleeding vessels while one patient died due to aspiration immediately on admission. No recurrence of bleeding was seen in the remaining 29 patients. It is concluded that bronchial artery embolization is an effective treatment for immediate control of life-threatening haemoptysis.
Acute Disease↗
The Robinson stapes prosthesis: a 15-year study.
A report on the stapedectomy procedure using the Robinson stainless steel stapes prosthesis over a 15-year period is presented in a study of 3,200 cases. Short-term results, long-term results, failures, and delayed complications are statistically analyzed. This implant is presently the most frequently used prefabricated stapes prosthesis in the country, and each year more otologic surgeons are adopting this surgical technique.
Adolescent↗
Gelatin film sandwich in tympanoplasty.
A technique is presented that utilizes two sheets of gelatin film as a sandwich to provide a scaffold for medial support and lateral cover to fascia grafts while permitting visual inspection of both fascia and tympanic membrane.
Fascia↗
Stapedectomy revision of the wire-Gelfoam prosthesis.
Revision procedures in which a vein graft with a Robinson stapes prosthesis was used are reviewed in 100 patients. In all cases a wire-Gelfoam stapes prosthesis had been used initially. The surgical findings were prosthesis malfunction, 48%; eroded incus, 16%; negative findings, 14%; footplate not removed, 11%; oval window fistula, 7%; and incus problems, 4%. Postoperatively, hearing in 70.5% of the patients with conductive hearing loss was within 10 dB and 84.5% within 20 dB. The high success rate is affected by the fact that patients with conductive hearing loss were separated from those with sensorineural hearing loss, a piston prosthesis on tissue was used in the revision surgical procedure, and patients with otosclerosis regrowth did not undergo revision. Surgical directives to minimize hearing loss included use of a tissue seal over the oval window; not reopening the oval window; monitoring the patient for dizziness; performing audiometric tests during surgery; leaving the wire in place in certain cases; and not revising the prosthesis in patients with otosclerosis regrowth.
Adolescent↗
Arteriovenous malformations of the mandible.
Arteriovenous malformations of the mandible may present with pulsatile tinnitus, pain, a bruit, loosening of teeth, or intraoral or facial deformation or discoloration. In the absence of these classic symptoms and signs, the unwary surgeon might attempt a limited excision, leading to massive intraoperative hemorrhage. Management includes external carotid as well as selective branch arteriography and preoperative arterial embolization with polyvinyl alcohol sponges and absorbable gelatin. Vessel ligation, mandibular resection, lesion excision, mandibular autografting, and intermaxillary fixation complete surgical treatment.
Adult↗
Polymerase chain reaction identification of human papillomavirus DNA in CO2 laser plume from recurrent respiratory papillomatosis.
Human papillomavirus (HPV) DNA was identified in the plume produced during CO2 laser vaporization of respiratory tract papillomata. The plume produced from CO2 vaporization was collected on Gelfoam pledgets that were affixed to suction tips evacuating the vapor plume from the operative field. The Gelfoam pledgets were snap frozen in liquid nitrogen, processed, and examined for HPV-6 and HPV-11 DNA by a polymerase chain reaction technique. Tissue and vapor-plume specimens were collected from 22 patients undergoing CO2 laser excision of laryngeal lesions. Seven patients had adult-onset recurrent respiratory laryngeal papillomatosis (RRP), 12 had juvenile-onset RRP, two had laryngeal carcinoma, and one had nonspecific laryngitis. HPV-6 or HPV-11 was identified in 17 of 27 vapor-plume specimens from RRP and in none of three from non-RRP lesions. All but one RRP tissue specimen contained HPV-DNA, and none of the non-RRP tissues contained HPV-DNA. When HPV was present in vapor, the same HPV type was found in the corresponding tissue specimen. Identification of HPV-DNA in the laser plume raises concern regarding potential risks from exposure to the plume--particularly to the endoscopic surgeon and the operating team. The practical concerns and effectiveness of the plume scavenging systems are discussed.
Air Microbiology↗
A universal ossicular replacement prosthesis: clinical trials of 152 cases.
An ossicular replacement prosthesis is described that advances implant design in several respects. The head is a flattened egg shape, which eliminates pressure points against the pars tensa and provided balance on the stapes. Dense hydroxylapatite ceramic provides maximal biocompatibility. The shaft, of either Teflon or Plastipore, is easily cut to size and is replaceable to minimize wastage. Interchangeable partial or total shaft variants are provided. Trials in more than 200 patients have produced optimal results. Among 152 mature patients in 85% of the good-risk cases, the air-bone gap closed to within 20 dB and in 65% to within 10 dB; in 69% of all cases the gap closed to within 20 dB. Extrusion rates were 5% in good-risk cases and 7% overall. Long-term extrusions have not occurred. Inasmuch as cartilage interpositioning is unnecessary, the prosthesis is rapidly prepared and implanted by an easily mastered technique.
Bone Conduction↗
Toxic shock syndrome after mastoidectomy.
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Chronic Disease↗
Palliative embolization of arterial renal tumour supply. Results in 10 cases.
Palliative occlusion of the arterial renal tumour supply was performed in 10 patients and the follow up is reported. Nine of the patients had no subsequent nephrectomy. Spongostan (99% gelatin) was used as the embolic material in 4 patients with the addition of steel coils in 2. Bucrylate was used in 6 cases. Six patients are alive with survival rates presently ranging from 3 to 24 months after embolization. Improvement of the survival time cannot be estimated but local symptoms such as hematuria and pain may be treated in those patients with renal tumours who are not considered for surgery.
Aged↗
Transcatheter arterial embolisation in nasopharyngeal angiofibroma.
Transcatheter arterial embolisation using gelfoam particles has been used in 4 young male patients with nasopharyngeal angiofibroma. The procedure proved to be extremely useful preoperatively in controlling and limiting profuse bleeding during surgery, allowing total excision of the tumor.
Adolescent↗