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At least 757 records · Page 42Linked to original sources
PubMed2000

Versailles minimal dataset for diagnosis of ALS: a distillate of the 2nd Consensus Conference on accelerating the diagnosis of ALS. Versailles 2nd Consensus Conference participants.

The 2nd Consensus Conference (Versailles) recommended that an ALS knowledge-base for initial healthcare providers, diagnosing neurologists and confirming neurologists should be defined to include a simplified version of diagnostic criteria less formal than the World Federation of Neurology El Escorial Revisted Criteria ('ALS diagnosis - An algorithm'), a set of rules concerning red flags which should increase the suspicion of ALS as the diagnosis and minimize the time between suspicion and referral for confirmation of diagnosis ('ALS axioms of referral'), as well as a site of symptom onset-specific checklist of minimal clinical examination, neuroimaging, electrodiagnostic, pulmonary function and laboratory test information required to confirm the diagnosis of ALS ('Versailles minimal dataset'). Although introductory discussions addressed the advantages and disadvantages of earlier diagnosis, false-positive or false-negative diagnosis, the frequency of follow-up and what potential biological markers to be followed, these issues will have to be further evaluated at future consensus conferences.

Diagnosis, Differential↗
PubMedDate not supplied

Monitoring for N,N-dimethylformamide and N,N-dimethylacetamide with a diffusive sampler using distilled water as an absorbent.

To obtain an appropriate sampling method for evaluating individual workers' exposure concentrations to chemicals highly soluble in water, the suitability of LiPS (liquid passive sampler) as diffusive sampler was examined. Although adsorbed chemical substances with activated carbon felt being used as the adsorbent must be desorbed in such samplers, this process can be omitted by using liquid as the absorbent. This kind of simplification can be utilized for water-soluble solvents such as N,N-dimethylformamide (DMF) and N,N-dimethylacetamide (DMAC). In laboratory experiments DMF and DMAC levels determined by this method were sufficiently correlated with exposure concentrations, exposure duration, and cumulative exposure levels. The sampling rates for DMF and DMAC obtained from these results were 0.50 and 0.43 mL/min, respectively, and the theoretical sampling rate for DMF obtained using Fick's diffusion formula was consistent with the experimental value. The effects of relative humidity, wind velocity, and temperature on the measured values were negligible within the range expected in a practical industrial environment. In a field survey the exposure concentrations for 38 workers handling DMF in the process of manufacturing spandex fiber and polyurethane gloves were determined both by this method and by the National Institute of Occupational Safety and Health (NIOSH) method, in which silica gel tubes are used. The DMF concentrations detected by the two methods were comparable (Y = 0.912X, correlation coefficient: 0.932). This LiPS method proved to be useful in determining the concentrations of DMF and DMAC to which workers were exposed.

Absorption↗
PubMed1979

[Usage of feeding yeast "Fermosin" grown on mineral oil distillate in animal nutrition. 2. Digestibility of the nutrients of Fermosin feeding yeast on broilers (chickens) and fattening pigs].

The digestibility of the nutrients of Fermosin was tested on pigs and the following values were ascertained: organic matter=86%, crude protein=89% and N-free extractives=83%. The net energy ascertained on the basis of the content of nutrients and the digestibility of the nutrients of Fermosin amounts to 617 energetic feed units for pigs/kg dry matter. The true digestibility of the amino acids of Fermosin was determined on pigs and chicken. For lysin the true digestibility was ascertained as 95% (pigs) and 73% (Broilers). Due to the different digestion abilities of the two animal species, corresponding differences in the digestibility of the other amino acids were found as well.

Animal Feed↗
PubMed1958

The freezing point depression of mammalian tissues after sudden heating in boiling distilled water.

The calculated freezing point depression of freshly excised boiled mammalian tissue is approximately the same as that of plasma. The boiling procedure was chosen to eliminate the influence of metabolism on the level of the freezing point depression. Problems created by the boiling, such as equilibrium between tissue and diluent, change in activity coefficient by dilution, and loss of CO(2) content, are discussed. A frozen crushed tissue homogenate is hypertonic to plasma. Boiling and dilution of such hypertonic homogenate exposed to room temperature for 5 to 15 minutes did not produce significant or unexplicable decreases in its osmotic activity. Moreover, freezing and crushing of a boiled diluted tissue did not produce any increase of the isoosmotic level of freezing point depression. It is possible to explain these data either with the hypothesis of hypertonic cell fluid or with that of isotonic cell fluid. In the case of an assumed isotonic cell fluid, data can be explained with one assumption, experimentally backed. In the case of an assumed hypertonic theory data can be explained only with the help of at least three ad hoc postulates. The data support the validity of the classical concept which holds that cell fluid is isotonic to extracellular fluid.

Animals↗
PubMed1994

A selective separation of alcoholic beverages and distilled wines by gas chromatography.

The MFE-Vinicol column (Análisis Vínicos; Spain) was developed for the analysis of alcoholic beverages. Fusel alcohols at low concentrations, including 2-propanol, methanol, ethyl acetate, and ethyl butyrate, are determined by a single temperature-programmed analysis using this column. This column has important advantages over the official columns recommended by the Association of Official Analytical Chemists and other official methods for this kind of analysis.

1-Propanol↗
PubMed1999

Distilling the literature: a randomized, controlled trial testing an intervention to improve selection of medical articles for reading.

PURPOSE: To test whether an academic detailing intervention would improve journal reading among residents. METHOD: In 1995-96, the authors conducted a randomized controlled trial at two family medicine residencies in Missouri. Fifty-nine family practice residents were randomized into two groups identical in baseline characteristics; 29 received individual 15-minute educational presentations, based on academic detailing, that emphasized careful selection of medical journal articles for reading. The authors measured the percentage of important journal articles of which the residents were aware, the percentage of those they had read (either abstract only or the whole article), and the percentage of correctly answered knowledge questions. RESULTS: Despite randomization, the residents in the control group indicated on the pretest that they were more likely than were the residents in the intervention group to be aware of and to have read abstracts from selected articles. However, when comparing pretest with posttest results, the intervention group recalled 18.2% (95% CI, 2.0, 34.0) more articles and correctly answered 16.6% (95% CI 3.0, 29.9) more knowledge questions than did the control group. CONCLUSION: A brief intervention increased residents' recall of important articles and knowledge of those articles' conclusions.

Decision Making↗