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At least 757 records · Page 42Linked to original sources
PubMedDate not supplied

Proposal for a new distributed database of macromolecular and subcellular structures from different areas of microscopy.

In this work we address the problem of information access that arises in the field of three-dimensional structure determination, by means of image processing, from data obtained by various types of microscopy. A prototype of a distributed database containing three-dimensional structural information is presented. In this database the volume information is linked, if possible, to other sources of catalogued information such as sequence data, atomic coordinates, and bibliographies. The solution we propose is sufficiently general to be applicable to data in other fields of biomedical science.

Computer Communication Networks↗
PubMed1998

Informatics for mouse genetics and genome mapping.

Bioinformatics has become an essential part of biological research. The rapid pace of technology development and the ability to carry out biological experimentation in large scale require computerized systems for data management, analysis, and display. Experimentation with the mouse, a major model organism of the Human Genome Initiative, has intensified the need for bioinformatics tools for mouse mapping and genome analysis. This article describes the Mouse Genome Database in the United States, a primary resource for mouse genomic data, as well as resources at the Mammalian Genetics Unit in the United Kingdom and the Animal Genome Database of Japan. Internet addresses are provided for major genetic and physical mapping resources, major genome data sites, and resources of molecular information.

Animals↗
PubMed1991

The use of X-terminals as clinical workstations.

The Medical Computer Facility at the Fox Chase Cancer Center has installed X-terminals in patient examination rooms and at nursing stations for clinical data access by physicians and nurses. The X-terminals are connected to UNIX operating system RISC processors via Ethernet. The RISC processors communicate with databases on a minicomputer cluster. Simultaneous presentation of textual (e.g., pathology and radiology reports) and graphical (e.g., clinical laboratory results) clinical data is provided under X-Windows. CT and MRI images can also be displayed in windows. Our experiences implementing X-terminal clinical workstations in a production environment will be discussed.

Cancer Care Facilities↗
PubMed1990

Defining the application portfolio for an integrated hospital information system: a tutorial.

Although many successful applications in the hospital environment have been introduced and implemented, hospital information systems have had little impact upon the daily operation of hospitals. Furthermore, integrated hospital information systems, although vital to the hospitals' functioning, have proved to be more complicated to develop and difficult to harness than expected. This paper discusses the need for an integrated hospital information system and provides a framework for the development of its application portfolio. The scope of such a system is the integration of the medical, administrative and fiscal information elements of the hospital into a unified systems environment.

Computer Communication Networks↗
PubMed1987

Extending the capabilities of a laboratory computer system through cooperative processing.

The concept of cooperative processing within the context of a hospital or laboratory computer systems environment is introduced. Two examples that produce graphical display of laboratory data are described to illustrate cooperative processing's ability to enhance a system's functionality without placing significant additional burden on system resources.

Clinical Laboratory Information Systems↗
PubMed1993

Hydra: a C-language environment for real-time DOS multitasking at the bedside.

Patient monitoring at the bedside is an inherently parallel job, best handled by multiple individual tasks running concurrently. Cost and diffusion considerations strongly favor the use of PC's at the bedside, but their most widespread operating system, DOS, is not built for multitasking. Hence, a software platform in C language has been prepared, allowing the intermediate programmer to easily write independent modules which will then run simultaneously without conflicts. Such a platform aims at allowing effortless sharing of data among concurrently running processes, while providing strong insulation between tasks, enough to allow multiple copies of any one task to run simultaneously unknown to each other. A cooperative, memory sharing multitasking paradigm has been chosen, which offers fine granularity of timeslicing and low execution overhead at the price of some loss in generality of design. Speed, data exchange capability and number of stackable windows are greater than with commercial packages like Windows or LabWindows. Dynamical reprioritization of tasks is built in, allowing the computerized monitor to focus its attention and resources on urgent tasks.

Algorithms↗
PubMed1995

Teleradiology/telepathology requirements and implementation.

Teleradiology and telepathology form an integral part of the telemedicine concept. Teleradiology is becoming a mature technology because of advances in imaging technology, database design and communications infrastructure and capabilities. Telepathology has also made significant progress but more development is needed in the definition of required images, database design and standards. While the requirements of most clinical applications of teleradiology are well established, telemammography still presents some impediments. Technical difficulties in telemammography are presented in terms of the lack of a clinically accepted digital imaging system and large data volume required per image. Another important aspect in tele-imaging is the database question. Workstations constitute a window into database. Comprehensive database development is the most difficult and expensive technology for tele-imaging and operational features of such systems are discussed. Finally, we explore current examples of the use of telepathology and teleradiology in the global telemedicine context.

Computer Communication Networks↗
PubMed1995

Synchronous and asynchronous telemedicine.

This paper outlines the differences between telemedicine applications in terms of their synchronous or asynchronous nature. The differences in the demands of these two forms of telemedicine are significant and should be considered in the development of any telemedicine system. It is the asynchronous applications that are most likely to provide real change in the practice of medicine.

Computer Communication Networks↗
PubMed1995

Defense Simulation Internet: next generation information highway.

The Department of Defense has been engaged in the Defense Modeling and Simulation Initiative (DMSI) to provide advanced distributed simulation warfighters in geographically distributed localities. Lessons learned from the Defense Simulation Internet (DSI) concerning architecture, standards, protocols, interoperability, information sharing, and distributed data bases are equally applicable to telemedicine. Much of the vision and objectives of the DMSI are easily translated into the vision for world wide telemedicine.

Computer Communication Networks↗
PubMed1989

Distributed computer system for capture, analysis and display of biological data.

A distributed real-time computer system has been developed to automate the collection, analysis and display of biological (pharmacological) data. It comprises a series of laboratory interface devices (CED 1401/1609) connected to a micro-VAX II via multiple IEEE-488 buses. The micro-VAX II is integrated to the main site computers using Ethernet running DECnet. The micro-VAX II system supports a multi-user, multipreparation and multitasking environment and it provides rapid transfer, storage, analysis and display of data. The system saves the pharmacologists from the manual analysis of their data, typically saving them four days of analysis per experiment and has improved both the quality of data detected and their subsequent analysis. Also, the development of a standard data capture procedure on common hardware along with the modular design of application software has almost quartered project development times.

Computer Communication Networks↗
PubMedDate not supplied

Use of computers in pediatrics: basic aspects.

Computer: 1. An electronic device designed to accept data, perform prescribed mathematical and logical operations at high speed, and display the results of these operations. 2. A person who computes; computist (1640-50).

Computer Communication Networks↗
PubMed2004

A hierarchical architecture of centralized monitoring and controlling system and its high-performance and interoperability protocol.

This paper describes a hierarchical architecture and a high-performance and interoperability protocol for centralized monitoring and controlling systems (CMCS). The protocol we proposed can interoperate different monitoring and controlling systems constructed by different companies, each with different functions and communication protocols. The protocol reduces the amount of traffic and has real-time and high-performance advantages. The protocol was implemented in CMCS for telecommunication power supply and air-conditioner used by the Telecommunication Bureau of Zhejiang Province. This paper deals with the hierarchical architecture and function of CMCS and packet format, command ID, and SDL description of its protocol. We also discuss the properties of the interoperability and performance of the protocol in this paper.

Algorithms↗