Search PubMed⌕ Search

SEARCH · Search PubMed

Results for “CONDITIONING”

Search indexed PubMed citations on genomics, clinical trials, systematic reviews and public health. Explore titles, authors and supplied subject terms, then open the PubMed record.

Quote a phrase for an exact phrase match. Source license links do not imply unrestricted reuse.

At least 757 records · Page 42Linked to original sources
PubMed1992

Conditioned tolerance to morphine hypoalgesia: compensatory hyperalgesia in the experimental group or conditioned hypoalgesia in the control group?

Five experiments used rats to examine the role of noxious stimulation in the development of contextually controlled morphine hypoalgesic tolerance and in the mediation of this tolerance by an associated hyperalgesic response. There was evidence for contextually controlled tolerance to morphine's hypoalgesic effects and an associated hyperalgesic response in rats injected with morphine and trained with noxious stimulation, but not in rats repeatedly exposed to morphine in the absence of that stimulation (Experiments 1 and 5). Latent inhibition (Experiment 2) and extinction (Experiment 3) of tolerance also depended upon pairing drug-related cues with noxious stimulation. The level of sensitivity-reactivity to noxious stimulation in morphine-tolerant rats tested with the drug was related to the intensity of the noxious stimulation that had been paired with the test context (Experiment 4). The results were interpreted to mean that some of the evidence for a Pavlovian involvement in tolerance development can be explained in terms of morphine's interference with the acquisition, but not with the expression of the hypoalgesic response otherwise acquired by cues paired with noxious stimulation.

Animals↗
PubMedDate not supplied

[Interhemispheric asymmetry of the spatial-temporal potentials of the human cerebral cortex under various conditions of the formation of verbal conditioning].

It was shown on the basis of electrophysiological data in 60 healthy subjects that the interhemispheric brain asymmetry in the course of formation and actualization of the verbal set depends on the context of the cognitive activity. More complex cognitive activity results in a development of regional interhemispheric differences in the studied characteristics of the spatiotemporal organization of cortical potentials. These differences are most spectacular in the frontal areas of the cortex.

Adult↗
PubMedDate not supplied

[The effect of piracetam and nicergoline on conditioned-reflex memory under conditions of extreme exposure].

The effects of nicergoline and piracetam on the learning of avoidance response and its restoration after disturbance produced by unexpected changes of the previously established cause-effect relations in experimental environment were studied. It was found that both drugs improve the learning, nicergoline being the most active in the initial period of training, meanwhile piracetam--beginning from the third day. The drugs prevent disturbance of the avoidance response but piracetam is more effective.

Acoustic Stimulation↗