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At least 757 records · Page 42Linked to original sources
PubMed1990

[A method of hermetic sealing of the bronchial stump following resection of the lungs in patients with tuberculosis].

The article presents a new bronchus stump sealing technique after pneumonectomy in tuberculosis patients. A characteristic feature of the proposed technique is the use of suture appliance in conjunction with xenoperitoneum saturated with biologically active substances and fixed during operation by peribronchial interrupted sutures beyond the regeneration zone. A unique methodology of the xenoperitoneum sealing, including sterilization, freezing, drying and medicinal solution treatment processes, is described. Experimental and clinical observations suggest that the proposed technique is advantageous.

Adult↗
PubMed1989

[Re-epithelialization of ectropion by topical application of an amniotic membrane after long preservation].

Treatment of ectropion of the portio presents numerous applicational problems, not least the psychological one of the woman who often refuses to carry out DTC because she considers it painful and it involves long periods of sexual inactivity. The possibility of using amniotic membranes to rapidly stimulate re-epithelization of ectropion of the portion of dimensions greater than 0.5 cm is examined.

Amnion↗
PubMed1989

[Algimaf treatment of trophic ulcers].

A new biologically active preparation, algimaf, developed at the All-Union Research Institute for Medical Polymers, stimulates the regenerative processes, is characterized by analgesic, antiedematous, manifest antibacterial and hemostatic effects, promotes the formation of hardly visible cicatrices, and is a highly effective means for the management of trophic ulcers of the skin.

Adult↗
PubMedDate not supplied

Soluble collagen disks for the treatment of dry eye syndrome.

We evaluated the efficacy of soluble ocular inserts made from porcine scleral collagen for the treatment of dry eye syndrome. The 22 patients enrolled in this pilot study were asked to grade their pretreatment symptoms and to document the frequency of artificial tear administration. Schirmer tests, fluorescein and rose bengal staining, and impression cytology of the conjunctival epithelium were also performed at the initial evaluation. Patients were evaluated in this fashion at 3-4, 6-8, and 18-20 weeks after initiation of treatment. We observed statistically significant improvement in symptomatology and reduced necessity for artificial tear administration. There was no significant change in rose bengal staining or impression cytology results. (The absence of objective findings suggests the possibility of a placebo effect.) These findings indicate that soluble collagen inserts may be useful in treating dry eye syndrome.

Adult↗
PubMed1987

Local wound care in the diabetic.

Since wounds in patients with diabetes will heal slowly at best, and since they are so much more susceptible to infection and the infection will be more devastating, the old adage of "first do no harm" must be adhered to. Diabetics have poor circulation, poor resistance to infection, and poor local nutrition. Their white blood cell killing power is decreased by the hypoxia from poor circulation and by the periodic hyperglycemia. The periodic hypoglycemia and decreased insulin interferes with the energy for healing and for host defenses. Because of this poor healing and low resistance, the use of strong, toxic chemicals should be avoided. They all inhibit healing and/or increase the risk of infection. Vigorous, repeated debridement of necrotic, devitalized tissue along with old blood, exudates, and tissue fluids is essential. This includes sharp debridement and mechanical debridement through high-pressure irrigation and frequent wet to dry fine mesh gauze dressings. The choice of bandaging material should be determined by the desired action on the wound, such as protection, debridement, and so on. The idea is to restore the conditions in the wound to normal physiology.

Asepsis↗
PubMed1988

[Skin transplantation or artificial skin replacement].

Temporary cover of skin defects, using artificial material, cannot be a substitution for autologous material. Heterologous skin grafts may turn out to be sources of infection. A combination of artificial skin of collagen preparations with epithelial cell cultures is a new alternative to exclusive autologous transplantation. Only limited surfaces so far can be covered by means of epithelial cultures.

Bandages↗
PubMed1988

[Epithelium transplantation with cultivated keratinocytes].

Efforts for a skin substitute from cultured cells have been made since many years. Epidermal cells are able to proliferate in culture vessels under strictly defined culture conditions. The gained expanded epithelial layer can be used as transplant. The culture methods of Green and Eisinger are discussed. In the last couple of years in vitro expanded epithelium was used as wound coverage, especially for major burns. Autologous transplanted epithelium is accepted perfectly under optimal wound bed conditions. Reports on the acceptance of allogenic transplanted cultivated keratinocytes are contradictory, possibly so far unidentified antigens are responsible for the rejection. To optimize the skin substitute keratinocytes can be cultured on different mesenchymal substrates. Possibly epidermal appendages can be included in the future.

Bandages↗
PubMedDate not supplied

Temporary skin substitutes for burn patients: a nursing perspective.

The conversion of an open wound to a closed wound is the primary focus in caring for the burned patient. When there are inadequate amounts of noninjured skin to cover the open wound, alternative methods for wound coverage are indicated. Temporary skin substitutes are materials designed to be placed on an open wound to temporarily restore an impaired barrier. These materials may be left on until the wound is healed or until replaced by the patient's own skin. Results of a nationwide survey are reported which identify the various products available for use as skin substitutes. Skin substitutes discussed are pigskin, allograft, and Biobrane. OpSite, Xeroform, and scarlet red are also included. The properties, indications for use, and application procedures for these skin substitutes are described.

Bandages↗
PubMedDate not supplied

Comments from the University of South Alabama Burn Center.

The above discussion summarizes our current treatment protocols at the University of South Alabama Burn Center. These are always undergoing evaluation and change. There are many materials currently available for treating the burn wound and even more new ones on the horizon. The efficacy of these materials is often unit dependent, and because of specific unit microbial flora may produce wonderful results at one center and poor results at another. Constant review of outcome is mandatory. The ideal skin substitute for all wounds and all clinical situations does not exist. The clinician must be thoroughly familiar with the properties of many products and be prepared to change from one material to another as the clinical situation dictates.

Alabama↗