SEARCH · Search PubMed

Results for “Atrial Flutter”

Search indexed PubMed citations on genomics, clinical trials, systematic reviews and public health. Explore titles, authors and supplied subject terms, then open the PubMed record.

SourceResearch connectionFrom yearThrough year

Quote a phrase for an exact phrase match. Source license links do not imply unrestricted reuse.

At least 757 records · Page 42Linked to original sources

PubMed2004

[Cardiac tamponade with paroxysmal atrial flutter controlled by antituberculous therapy].

We report a rare and unique case of possible extrapulmonary tuberculosis in an 83-year-old man who had cardiac tamponade and paroxysmal atrial flutter. The patient was admitted to our hospital because of syncope. The cardiac tamponade and paroxysmal atrial flutter were treated by pericardiocentesis and drainage of bloody pericardial fluid. Mycobacterium tuberculosis was not detected in diagnostic specimens, nor was any evidence of malignancy found. The remarkable elevation of adenosine deaminase and the predominance of lymphocytes in the pericardial fluid, considering the past history of tuberculosis, led to a diagnosis of extrapulmonary tuberculosis. After receiving standard antituberculous therapy by ethambutol, isoniazid, and rifampicin, the patient recovered and has remained well up to the present day. Thirty-six months have passed since his recovery without the recurrence of cardiac tamponade or any other cardiac events.

Aged↗

PubMed2004

Spontaneous transition from atrial fibrillation to typical atrial flutter during catheter ablation of the pulmonary vein.

A 71-year-old male patient was admitted for catheter ablation of the pulmonary veins to treat paroxysmal atrial fibrillation. Atrial fibrillation originating from the left superior pulmonary vein was induced after a pause of atrial pacing under isoproterenol infusion and became sustained. Spontaneous transition from atrial fibrillation to typical atrial flutter was noted after complete isolation of the pulmonary vein focus from the left atrium. Subsequently linear ablation of the cavotricuspid isthmus was created with completely bi-directional isthmus conduction block. We hypothesized that ectopic pulmonary vein focus played an important role in the spontaneous conversion of atrial fibrillation to typical atrial flutter, and complete isolation of the pulmonary vein could stop the spontaneous transition between the two atrial tachyarrhythmias.

Aged↗

PubMed2005

Performance of a new cardiac cryoablation system in the treatment of cavotricuspid valve isthmus-dependent atrial flutter.

We sought to evaluate prospectively the safety and efficacy of cryothermal energy to ablate typical atrial flutter (AFL). Ablation of cardiac tissue using cryothermal energy has recently been developed as an alternative to radiofrequency energy, which may offer certain advantages in the treatment of AFL. This prospective, multicenter nonrandomized study of a new catheter-based system for the treatment of cavotricuspid isthmus (CTI)-dependent AFL enrolled patients between 18 and 75 years of age. The CTI dependence of AFL was confirmed at electrophysiologic study with activation mapping and/or entrainment. Patients with atrial septal defect, recent myocardial infarction, left ventricular ejection fraction <0.30, or prior AFL ablation were excluded. Cryoablation of AFL was performed in 48 patients from 11 centers. The procedure was immediately successful in 45 patients (94%), and effective in 30 of 40 patients with complete data available at 6 months. Cryoablation is a promising new treatment of CTI-dependent AFL refractory to medical therapy. Further improvements in catheter design and intravascular sheaths will be tested in a larger multicenter trial.

Atrial Flutter↗

PubMed1986

Fragmented electrograms and continuous electrical activity in atrial flutter.

Multiple endocardial bipolar electrograms were recorded in 13 patients with atrial flutter (AF) to locate areas of fragmented electrical activity. Stable fragmentation patterns were found in each case, covering between 36% and 100% of the flutter cycle. Double or triple spike patterns were common. The direction of atrial activation was approximately defined in 11 patients, and in all of them at least part of the areas showing fragmentation was included in the circuit. In 1 patient an area of continuous electrical activity was found. AF circuits appeared to be included in the right atrium in 12 patients and in the left atrium in 1 patient. During atrial stimulation changes in fragmented electrograms coincided with changes in AF pattern before its interruption, while restoration of stable AF after stimulation was accompanied by reappearance of previous stable fragmented electrograms. In 6 patients electrograms were recorded after sinus rhythm was reestablished, and all showed marked decreases or disappearance of fragmentation. It is concluded that fragmented electrograms are often found in AF and may be related to abnormal local conduction in relation to the reentrant activation circuits.

Adult↗

PubMed1999

The failing Fontan with atrial flutter: a successful surgical option.

Two successful cases of eliminated atrial flutter and improved clinical status for Fontan patients are presented. An operation combining introduction of an extracardiac conduit for the Fontan connection, to direct all systemic venous blood away from the atrium, and atrial pathway division and cryoablation, is a useful surgical option for failing Fontan patients.

Adolescent↗

PubMed2005

Acute right coronary artery occlusion following radiofrequency catheter ablation of atrial flutter.

Acute right coronary artery occlusion following radiofrequency ablation. We report the first known case of acute right coronary artery occlusion following Radiofrequency (RF) ablation for atrial flutter in a patient without known prior coronary disease. Our patient developed acute chest pain and inferior ST-segment elevation immediately following the procedure. Emergent cardiac catheterization was performed, revealing an occluded distal right coronary artery, which was immediately stented. Acute coronary occlusion should be considered in the differential diagnosis of patients, with or without coronary artery disease, who experience chest pain following RF ablation for atrial flutter.

Acute Disease↗

PubMed1990

[Therapeutic value of programmed stimulation in atrial flutter].

The results of 181 therapeutic stimulations in cases of atrial flutter (a-flut) have shown that a-flut is terminated in a wide range by means of programmed stimulation (PS). A sinus rhythm (SR) was achieved in 68% of cases; out of these 21% changed to SR after brief atrial fibrillation (a-fib). Permanent a-fib was induced by means of PS in 32% of cases. In patients with previous coronary artery bypass surgery (ACVB) SR is to be reckoned with most frequently. SR occurs here in 89.5% of cases; in idiopathic a-flut in 71.8% of cases. In four further sub-samples SR must be expected in about two-thirds of cases. With congenital lesions after corrective surgery, as well as with aortic valve lesions without valve replacement, SR was achieved in 66.7% of cases, and in 64.7% of patients with coronary heart disease without previous coronary bypass surgery. SR resulted by means of PS in 64.3% of aortic lesions after a valve operation. In 76.7% of cases of mitral valve lesions with postoperative a-flut the result was permanent a-fib. A-fib appeared in 80% of mitral lesions without heart operation. The influence of a heart operation is minimal, with SR after PS only occurring with more significant frequency in patients after coronary bypass surgery. The result of the stimulation is not influenced by the duration of the postoperative phase. The techniques of stimulation, with the exception of high rate pacing, are of equal value. Even a persistent a-flut can be terminated by means of high rate pacing, with an a-fib thereby resulting more frequently. In cases of spontaneous as well as post-operative a-flut therapeutic stimulation is an effective form of therapy.

Adult↗

PubMed1997

Simplified electrophysiologically directed catheter ablation of recurrent common atrial flutter.

BACKGROUND: Despite verification of bidirectional conduction block after radiofrequency (RF) catheter ablation in the inferior vena cava (IVC)-tricuspid annulus (TA) isthmus, recurrence of common atrial flutter is relatively common. Although complete linear reablation is usually performed, we evaluated a simplified electrophysiological strategy selectively targeting recovered conducting isthmus tissue. METHODS AND RESULTS: Twenty-one patients (18 men and 3 women, age, 54+/-10 years) with a recurrence of typical atrial flutter 6+/-7 months after an apparently successful catheter ablation in the IVC-TA isthmus prospectively underwent electrophysiologically targeted reablation during flutter. Sites with narrow electrograms or fractionated electrograms interposed between adjacent sites with double potentials considered to represent gaps were ablated without movement of the catheter. Mapping showed that 18 of 21 patients had a single gap. Successful ablation required a single application in 14 patients and, in the group as a whole, a median of one application (mean, 2+/-2; range, 1 to 11) with resultant bidirectional block in 13 of 16. A single narrow electrogram (duration, 48+/-6 ms; amplitude, 0.1+/-0.05 mV) was noted at the successful site in 11, whereas a fractionated electrogram (97+/-32 ms, 0.05+/-0.04 mV, P<.05) was noted in 9. There were four additional recurrences during a follow-up at 7+/-5 months; three were similarly ablated with a median of one pulse. CONCLUSIONS: Transmural ablation lesions in the isthmus can be recognized during flutter by double potentials separated by an isoelectric interval. Postablation recurrent flutter is usually due to a single discrete recovered gap; this is represented by a single or a fractionated potential spanning the isoelectric interval of adjacent double potentials, which can be selectively targeted to minimize repeat ablation.

Adult↗

PubMed1996

Electrophysiological effects of catheter ablation of inferior vena cava-tricuspid annulus isthmus in common atrial flutter.

BACKGROUND: The electrophysiological mechanisms for successful catheter ablation of atrial flutter (AFI) targeting the inferior vena cava-tricuspid annulus (IVC-TA) isthmus have not been determined. METHODS AND RESULTS: Twenty patients with common AFI were studied. All had inducible common AFI, and 8 of them had both common and reverse AFI. Right atrial (RA) activation sequences were investigated during pacing from sites proximal (low lateral RA) and distal (proximal coronary sinus) to the IVC-TA isthmus both during entrainment of common or reverse AFI and during pacing in sinus rhythm. This was repeated after ablation. During pacing in sinus rhythm from the low lateral RA, the septum was activated by caudocranial and craniocaudal wave fronts. Similarly, during pacing from the proximal coronary sinus, the lateral RA was activated by two wave fronts. Catheter ablation of the IVC-TA isthmus induced dramatic changes in mapping due to the loss of caudocranial wave front in all but 1 patient. The septum and the lateral RA were activated by a single craniocaudal front as during entrainment of reverse or common AFI, respectively. After a follow-up of 8 +/- 2 months, common or reverse AFI occurred in 4 patients. Two had no or only unidirectional changes in the isthmus conduction induced by ablation. The other 2 had a late recovery of conduction. CONCLUSIONS: The present study provides evidence that the mechanism of successful AFI ablation targeting the IVC-TA isthmus is local bidirectional conduction block. This change can be used as a new and complementary electrophysiological end point for the procedure. AFI recurrences are associated with failure to achieve a permanent block.

Aged↗

PubMed2002

[Biochemical markers of myocardial damage after high-energy radiofrequency ablation of atrial flutter. Value of troponin I].

Creatinine phosphokinase and its MB iso-enzyme do not allow assessment of the degree of tissue necrosis after radiofrequency ablation. Cardiac Troponin I and myoglobin, new markers of myocardial lesions, are rarely used in this indication. The aim of this prospective study was to measure and compare serum markers of myocardial damage after high energy radiofrequency ablation of atrial flutter with an 8 mm distal electrode catheter. The authors measured serum cardiac Troponin I, myoglobin, creatinine phosphokinase and its MB iso-enzyme levels before and 4, 12 and 24 hours after radiofrequency ablation of common atrial flutter in 23 consecutive patients. The same markers were also measured in a control group of 9 patients undergoing electrophysiological investigation without radiofrequency ablation. All ablation procedures were simple with an average of 12.6 +/- 6 applications of radiofrequency. Bidirectional isthmic block was obtained in 22 of the 23 patients. The mean Troponin I levels were 0.01 microgram/l before ablation, 0.87 +/- 0.77 at the 4th hour (p < 0.001 versus control), 1.16 +/- 1.2 at the 12th hour (p < 0.001 versus control) and 0.7 +/- 0.63 microgram/l at the 24th hour (p < 001 versus control) after ablation. Only 13% of patients had cardiac troponin levels greater than the threshold of significant myocardial damage (> 2 micrograms/l) with a higher average number of radiofrequency applications than the rest of the group: 15.2 +/- 1 versus 11.5 +/- 5.1 (p < 0.05). An abnormally high level of markers was found in the ablation group for 19 patients (84%) with Troponin I (> 0.4 microgram/l), for 10 patients (43%) with the MB iso-enzyme (> 8 Ul/L), and for 1 patient (4%) with myoglobin (> 90 micrograms/l), and in no patient for creatinine phosphokinase (> 290 IU/L). All values were normal in the control group. The authors conclude that cardiac Troponin I is the most sensitive marker for myocardial cellular damage after high energy radiofrequency ablation of atrial flutter. The level of cardiac Troponin I seems to correlate with the number of applications of radiofrequency.

Aged↗

PubMed1998

Effects of procainamide on the excitable gap composition in common human atrial flutter.

The composition of the excitable gap (EG) in common atrial flutter (AF1) was determined before and during infusion of procainamide (PA) in 9 patients (6 men and 3 women; age 70 +/- 7 years). The EG was determined by introducing a premature stimulus after every 20th AF1 complex detected using a quadripolar electrode catheter placed just above the tricuspid valve. Diastole was scanned in 2- to 4-ms decrements to the atrial effective refractory period (ERP). The relationship between the coupling interval and the return cycle length (CL) determined a reset-response curve (RRC), which described the EG. PA (15 mg/kg) was administered during AF1 over 30 minutes and RRC was repeated at maximum AF1 CL. PA prolonged AF1 CL from 227 +/- 29 to 296 +/- 62 ms (P < 0.01) but did not terminate AF1. ERP during AF1 prolonged from 169 +/- 24 to 219 +/- 41 ms (P < 0.01). Control EG was 57 +/- 16 ms or 25% +/- 6% of AF1 CL and on PA EG was 77 +/- 30 ms (P = 0.01), which was still 26% +/- 7% of the CL. Without drug, RRC was mixed in eight cases demonstrating an EG composed of fully excitable tissue (10 +/- 4 ms or 19% +/- 10% of the EG) and partially refractory tissue (48 +/- 18 ms). PA did not change the duration of the fully excitable region (13 +/- 10 ms or 19% +/- 15% of EG). Peak PA plasma concentration was 47 +/- 20 mumol/L. PA prolonged AF1 CL, ERP, and EG duration but did not change the proportion of AF1 CL occupied by the EG. The persistance of fully excitable tissue at the head of the wavefront in the presence of PA may largely explain its inefficacy in the acute termination of common AF1.

Aged↗

PubMed2000

Electroanatomic magnetic mapping during ablation of isthmus-dependent atrial flutter.

INTRODUCTION: Although recent studies have demonstrated that the endpoint of isthmus conduction block is superior to that of termination and subsequent inability to induce atrial flutter (AFl), the optimal method for determining isthmus conduction block has not been determined. Electroanatomic magnetic mapping during coronary sinus (CS) pacing may provide a reliable endpoint for AFl ablation. METHODS AND RESULTS: Catheter mapping and ablation was performed in 42 patients with isthmus-dependent AFl. The patients were divided into two groups, based on procedural endpoint: Group I (28 patients) - isthmus conduction block was determined based on multipolar catheter recordings and electroanatomic mapping, and Group II (14 patients) - isthmus conduction block was determined by electroanatomic mapping during CS pacing alone. In Group I, ablation procedures were acutely successful in 25 of 28 patients (89 %). A 100 % concordance between the data presented by multipolar catheter recordings and electroanatomic mapping was noted in determining the presence or absence of isthmus conduction block. In Group II, ablation procedures were acutely successful in 13 of 14 patients, 13 (93 %). After a mean of 16.3+/-3.7 months follow up, there was 1 atrial flutter recurrence in the 38 patients (2.6 %) with demonstrated isthmus block at the end of the procedure. CONCLUSIONS: Electroanatomic magnetic mapping during CS pacing is comparable to the multipolar catheter mapping technique for assessing isthmus conduction block as an endpoint for AFl ablation procedures.

Adult↗

PubMed2000

Apical hypertrophic cardiomyopathy associated with life-threatening paroxysmal atrial flutter with a slow ventricular response: a case report.

A 58-year-old male patient had apical hypertrophic cardiomyopathy (HCM) associated with a life-threatening tachycardia due to atrial flutter. Following palpitation and dyspnea for 2-3 h, he became unconscious because of circulatory catastrophe, but was fully resuscitated. An electrocardiogram recorded just before the loss of consciousness revealed atrial flutter at a rate of 260 beats/min with a 2:1 ventricular response. He was diagnosed as having apical HCM based on the echocardiographic and left ventriculographic findings. Atrial stimulation at a rate of 150 pacings/min for 1 min caused a marked drop in systemic systolic blood pressure from 170 to 120 mmHg. The patient was treated with 150 mg of cibenzoline per day to prevent supraventricular tachyarrhythmias and to improve left ventricular diastolic function. At the time of the recent follow-up at 2 and a half years, he felt quite well.

Atrial Flutter↗

PubMed1998

[Combined use of left atrial transesophageal pacing and cordarone in atrial flutter].

AIM: To investigate the effectiveness of superfrequent transesophageal left atrial stimulation (TLAS) and its combination with cordarone in management of atrial flutter (AF). MATERIALS AND METHODS: 650 patients with paroxysmal AF underwent TLAS. The paroxysm duration varied from 1 hour to 1 month. In 312 patients TLAS was performed prior to treatment with antiarrhythmic drugs (group 1), in 338 patients--after intravenous administration of cordarone (group 2). RESULTS: Superfrequent TLAS has restored sinus rhythm (SR) in 85(27.2%) and 169(50%) patients of groups 1 and 2, respectively (p < 0.001). TLAS promoted conversion of AF in atrial fibrillation (AFi) in 185(59.3%) and 159(47.1%) patients of groups 1 and 2, respectively (p < 0.01). Moreover, SR recovered 24-48 hours after TLAS in 87(27.9%) and 64(18.9%) patients of groups 1 and 2 respectively (p < 0.01). Sinus rhythm recovered in a total of 172(55.1%) and 233(69.0%) patients, AF was converted to AFi in a total of 88(31.4%) and 95(28.1%) patients (p > 0.05) of groups 1 and 2, respectively. TLAS was uneffective in 42(13.5%) and 10(2.9%) patients of groups 1 and 2, respectively. CONCLUSION: Superfrequent TLAS is a highly effective and non-invasive modality in the treatment of paroxysmal AF. It promotes recovery of SR. In some patients TLAS induces AFi which is more controllable by medication as regards the heart rate. Cordarone contributes to the response to TLAS in patients with paroxysmal AF.

Amiodarone↗

PubMed1993

[New perspectives in the ablation of ectopic atrial tachycardia and atrial flutter].

The first experiences on non-pharmacological treatment of ectopic atrial tachycardia (EAT) and common atrial flutter (AFl) were performed by surgical techniques. The surgical abolition of EAT comprised the isolation, the excision or the cryoablation of the ectopic atrial foci using electromapping guide. The AFl was treated by extensive cryoablation of the slow conduction area responsible for the macroreentrant process located in the infero-posterior part of the right atrium (RA). Transcatheter ablation with DC-shock for the treatment of EAT was proposed in 1985 but the technique did not gain wide acceptance due to its risks. The same method was utilized for the treatment of AFl since 1987. Many preliminary studies reported on the use of transcatheter ablation with radiofrequency (RF) current as an energy source since 1992 and no major complications were encountered. According with our knowledge, 81 cases of permanent or iterative EAT were treated by RF in the world with a primary success rate superior than 90%. The low rates of recurrence are reported very early (within 24-48 hours) after the procedure; recurrencies are very easy to recognise and they are successfully ablated in a second session. Cases of EAT due to an ectopic focus localized in the RA are ablated from the superior or inferior vena cava approaches and cases of EAT related to a left atrial (LA) ectopic focus by a trans-septal approach (persistent foramen ovale or atrial septum puncture). On the basis of our personal experience regarding 7 cases (4 LA and 3 RA foci) the role of unipolar leads derived from the mapping catheter appears essential to select the target for RF applications.(ABSTRACT TRUNCATED AT 250 WORDS)

Adult↗

PubMedDate not supplied

Do different atrial flutter types carry the same thromboembolic risk?

Thromboembolic risk of atrial flutter (AFl) types has not been elucidated sufficiently in previous reports. The authors classified the patients according to surface electrocardiogram and electrophysiologic characteristics as those with typical AFl (37 patients, 78.4% male, mean age 59.8 +/-9.5 years) and atypical AFl (13 patients, 69.2% male, mean age 60.9 +/-6.9 years) and compared them regarding some clinical, echocardiographic, and hematologic parameters. An age- and gender-matched control group composed of 20 individuals without any organic heart disease in sinus rhythm was chosen (80% male, mean age 60.3 +/-7.9 years). Clinical features such as age, gender, organic heart disease, hypertension, diabetes mellitus, AFl duration, and the prevalence of paroxysmal atrial fibrillation were similar in both AFl groups. Echocardiographic parameters such as left ventricular ejection fraction, left atrial (LA) diameter, LA spontaneous echo contrast, and LA appendage emptying velocities were similar in both AFl groups. Fibrinogen, fibrin D-dimer, and thrombin-antithrombin III levels reflecting coagulation system activity were found to be increased in the patients with atypical AFl when compared with those with typical AFl and the control group (p < 0.001). In Pearson's correlation analysis, significant correlation between these hematologic markers and clinical and echocardiographic parameters were not found (p > 0.05). The coagulation system activity was found to be increased in patients with atypical AFl. Thus, anticoagulation due to the increased thromboembolic risk should be considered in patients with atypical AFl.

Age Factors↗

PubMed1991

[Fulguration of atrial flutter in man. A pathological case].

A 63 year old man with ischemic heart disease underwent two sessions of catheter ablation in the inferior right atrium for poorly tolerated resistant and recurrent atrial flutter. After endocavitary mapping and comparison with surface recordings of the f waves, a shock of 50 joules was delivered to the zone situated anteriorly to the inferior vena cava, under the orifice of the coronary sinus and behind the tricuspid valve. Early recurrence of the arrhythmia led to a second attempt and another 50 joules shock was administered to the same area. Another short term recurrence led to definitive nodohisian interruption with a 270 joules shock. Thirty months later, the patient died suddenly during an episode of cardiac failure. Macroscopic examination of the right atrium showed a zone of parietal congestion measuring 4 x 3 cm with a very thin, translucid, central zone measuring 3 x 1.5 cm, just anterior to the inferior vena cava in the right atrial free wall. Histological examination of this zone showed an intense, mutilating fibrosis dissociating the muscular fibres, of the pectinate muscle and even replacing the myocardium in certain regions. In the Eustachian valve, there were muscular fibres, probably representing the posterior internodal pathway, which were also fibrosed. These observations suggest that: 1) in view of the extreme thinness of the atrial wall at the site of ablation there is a high risk of perforation even when right endoatrial catheter ablation is performed with low energy shocks; 2) the posterior internodal pathway does not seem to be an essential component for atrial flutter.

Atrial Flutter↗

PubMed2004

Efficacy and safety of ibutilide vs. transoesophageal atrial pacing for the termination of type I atrial flutter.

AIMS: Comparing efficacy and safety of ibutilide vs. transoesophageal atrial pacing (ATP) for the termination of type I atrial flutter (AFL). METHODS AND RESULTS: Eighty-seven patients affected by AFL lasting between 2 h and 30 days were randomized in two groups: Group 1-i.v. ibutilide treatment, up to 2 mg, and Group 2-ATP, with "burst" and "ramp" pacing protocols. Sinus rhythm was restored in 36/45 (80%) patients in Group 1 vs. 18/42 (43%) in Group 2 (P<0.0005). In Group 1, mean AFL duration was 11.4 +/- 7.7 days in responders vs. 12.1 +/- 7.6 in non-responders (P=ns), while in Group 2 it was 2.7 +/- 1.4 vs. 14.2 +/- 5.4 days (responders vs. non-responders, respectively, P<0.0001); 30/36 (83%) responders in Group 1 had AFL >48 h vs. 10/18 (56%) responders in Group 2 (P<0.05). Non-sustained polymorphic ventricular tachycardia occurred in 2 patients in Group 1 vs. none in Group 2 (P=ns). It did not require any specific treatment except the interruption of ibutilide infusion. CONCLUSION: Both ibutilide and ATP proved to be safe and effective for recent onset type I AFL termination, but ibutilide was more effective when the arrhythmia had lasted longer than 48 h.

Aged↗