Search PubMed⌕ Search

SEARCH · Search PubMed

Results for “ADENOIDS”

Search indexed PubMed citations on genomics, clinical trials, systematic reviews and public health. Explore titles, authors and supplied subject terms, then open the PubMed record.

Quote a phrase for an exact phrase match. Source license links do not imply unrestricted reuse.

At least 757 records · Page 42Linked to original sources
PubMedDate not supplied

Cytologic features of adenoid basal carcinoma of the uterine cervix. A case report.

The cytologic features of a case of adenoid basal carcinoma of the cervix included large numbers of three-dimensional, somewhat-discohesive groups of intact cells with overlapping nuclei, a moderately high nuclear/cytoplasmic ratio, occasional peripheral palisading, finely granular chromatin, mild hyperchromasia and small nucleoli. The differential diagnosis with other entitities, including reactive endocervical cells and low grade adenocarcinoma of the cervix, is discussed. The acini, rosettes, pseudostratified nuclei with bare, "feathered" nuclei and columnar configurations seen in well-differentiated endocervical adenocarcinoma were absent. The distinction from reactive endocervical cells was difficult; adenoid basal carcinoma showed more numerous groups of cells, a higher nuclear/cytoplasmic ratio, palisading and more three-dimensional groups with a "windswept" appearance as compared to those with reactive atypia.

Adenocarcinoma↗
PubMedDate not supplied

[Repeated adenoidectomy and prevention of the recurrence of adenoid hypertrophy].

Basing on comprehensive clinical experience and the analysis of long- and short-term results of adenotomy, the author evaluates the effectiveness of this procedure, the causes of residual nasal respiration problems. The main reason of postoperative incomplete restoration of nasal respiration is suggested to be nonradical removal of the adenoid tissue which may result from specific features of the adenoids size, location, anatomical structure of the nasopharynx, the surgeon's equipment and experience, etc. The author thinks postadenotomy nasal problems should be managed with repeat operation which is recommended in the literature and has been practiced by the author for 30 years with the overall efficacy of 90%. Clinical symptoms, indications to repeat surgery are provided. Repeat adenotomy in a few days after the initial operation permits the author to reduce the percent of the vegetations recurrences in many patients.

Adenoidectomy↗
PubMed1994

Functional-anatomic correlation of eustachian tube obstruction related to the adenoid in a patient with otitis media with effusion: a case report.

Prospective randomized clinical trials have shown modest but significant reductions in morbidity from otitis media with effusion following adenoidectomy. However, the precise role of the adenoid in the pathogenesis of otitis media with effusion remains unknown. Some authors have hypothesized that the adenoid may compress or obstruct the Eustachian tube lumen, thereby causing middle ear underpressures and subsequent effusion formation. Functional-anatomic correlation for this theory is lacking. Herein, we present a single case of a pediatric patient with otitis media with effusion and manometrically proven active and passive Eustachian tube obstruction which was relieved by adenoidectomy. Photographic anatomic correlation is presented.

Adenoidectomy↗
PubMed1994

[A case of adenoid cystic carcinoma manifesting Garcin's syndrome--effectiveness of cerebrospinal fluid ferritin as a tumor marker in malignant CNS involvement].

We reported a 69-year-old man exhibiting Garcin's syndrome caused by adenoid cystic carcinoma of the right submandibular gland. The patient first experienced abnormal sensations in his right cheek, and the cranial nerves on his right side gradually became affected. He was admitted for hoarseness and dysphagia. Physical examination revealed a right submandibular mass, and neurological examination revealed that the first cranial nerve and the fifth to twelfth cranial nerves on the right side were affected. Laboratory examination showed a rise of both serum and cerebrospinal fluid (CSF) ferritin, suggesting an intracranial invasion of the submandibular tumor. But other tumor markers, CSF protein and cell counts, CSF pathologic study and radiological studies for the central nervous system (CNS) were all negative. A submandibular tumor biopsy revealed adenoid cystic carcinoma. The radiation therapy, including the skull base, provided relief of the patient's symptoms, the tumor was reduced and serum and CSF ferritin level decreased. It is possible that CSF ferritin is a sensitive marker for CNS involvement of malignant tumor because of its permeability of the blood brain barrier and the absence of correlation between serum and CSF.

Aged↗
PubMedDate not supplied

Primary adenoid cystic carcinoma of Bartholin's gland. A case report.

An extremely rare case of primary adenoid cystic carcinoma of Bartholin's gland in a 71-year-old woman is reported. With the working diagnosis of malignancy of Bartholin's gland on biopsy, she underwent a left radical vulvectomy with bilateral inguinal and pelvic lymphadenectomy and postoperative left vulvar irradiation. The cytologic and pathologic findings on the surgical specimens were distinctive. The imprint cytology of the cut surface of the tumor showed that the neoplastic cells were crowded and that some cells had a peripherally displaced nucleus. The nuclei were oval or round, and the quantity of chromatin was increased and fine. Some nuclei had prominent nucleoli. The cytoplasm was abundant. The surgical specimens showed the same findings as did cytology. the final diagnosis was primary adenoid cystic carcinoma of Bartholin's gland, postoperatively based on the cytologic and pathologic findings.

Aged↗
PubMed1993

[A clinical study of resected adenoid cystic carcinoma of the tracheobronchial tree].

From 1973 to 1990, 7 patients presented with a adenoid cystic carcinoma of tracheobronchial tree that was treated surgically. The locations were larger airways; 4 in the trachea, 1 in the carina, 2 in the basal bronchus. Surgical treatments were performed in all cases. The following resections were done: trachea only 3; carina 1; trachea plus larynx 1; left lower lobe (sleeve lobectomy) 1; left lung (pneumonectomy) 1. Except for tracheolaryngectomy and left pneumonectomy, all cases were undergone primary anastomosis. Operative death was only one patient who died of anastomotic separation. Irradiation was performed in 6 patients before or after operation. Two patients were died due to lung metastases or leukemia. According to the Kaplan-Meier's method, the 5 years survival rate of all patients was 68.6%. Our experience suggests that surgical treatment and adjunctive radiotherapy is beneficial in patients with adenoid cystic carcinoma.

Adult↗
PubMed1993

Primary adenoid cystic carcinoma of the middle ear and mastoid.

Two primary adenoid cystic carcinomas of the middle ear and mastoid are presented. This pathologic condition is uncommon and no large series exist in the literature. Adenoid cystic carcinoma could arise from ectopic salivary gland tissue located in the wall of the jugular bulb in proximity to the hypotympanum. These tumors demonstrate much invasion of bone and soft tissue. The surgical rationale in the management of this rare tumor is discussed.

Carcinoma, Adenoid Cystic↗
PubMed1993

[Adenoid cystic cancer of the breast. Case report and meta-analysis of the literature].

Adenoid-cystic carcinoma of the breast is considered a rare entity with a comparatively favourable prognosis. We report the case of a 58 year old woman and review another 150 cases published to date in the pertinent literature. The clinical course and outcome of 99 patients was evaluated by meta-analysis. Recurrence-free ten-year survival was calculated at 85.1 percent following mastectomy and at 45.7 percent after breast-conserving therapy (p < 0.05). Six of ten local recurrences and 7 of 8 distant metastases occurred 5 years or later after initial treatment. It is concluded that patients with adenoid-cystic carcinoma of the breast should be treated by primary mastectomy and extended follow-up is recommended.

Biomarkers, Tumor↗
PubMed1993

[Adenoid cystic carcinoma of the salivary glands. The value of postoperative radiotherapy].

The study of adenoid cystic carcinoma of the salivary glands is limited by the paucity of series described and the lack of prospective reports. The medical records of 21 patients with histologically proven adenoid cystic carcinoma seen between January 1975 and December 1991 were reviewed. The efficiency of postoperative radiotherapy both on locoregional control and overall survival was assessed. Seventeen patients underwent extensive surgery and postoperative radiotherapy. Three patients had recurrences in the surgery and postoperative radiotherapy group. Two patients who underwent surgery alone presented tumor recurrences. For the complex series the overall five and ten-year survival rates were 83% and 67% respectively. For the 17 patients in the surgery and postoperative radiotherapy group, five and ten-year survival rates were 87% and 77% respectively. These results show postoperative radiotherapy to be effective in decreasing the recurrence rate which is largely reported elsewhere.

Adult↗
PubMed1996

[Report of 3 cases of adenoid cystic carcinoma of the palate. Clinical, histological and therapeutical considerations].

Three cases of adenoid cyst carcinoma of the palate are reported. In this study clinical features, pathological findings, treatment and prognosis are analyzed. In the 1st and 2nd cases we unfortunately verified that the course of the tumors based in a slow-continuous infiltrating spread. Moreover, in our first patient a late diagnosis of it made the prognosis become worse. In the 1st one, radical surgery is proposed for the adenoid cyst carcinoma diagnosed at an early stage without tumoral dissemination.

Aged↗
PubMedDate not supplied

Expression of c-erbB family gene products in adenoid cystic carcinoma of salivary glands: an immunohistochemical study.

The tyrosine kinase receptor family, including the epidermal growth factor receptor (EGF-R), c-erbB2 and, more recently, the c-erbB3, has been recognized as being of particular importance in many human malignancies. This study was undertaken to define the role of c-erb B2 and c-erbB3 in adenoid cystic carcinomas (A.C.C.) of the salivary glands. Sixteen cases of A.C.C. were studied immunohistochemically, using antibodies against each erbB gene family product. EGF-R was not detected in any of these samples but c-erbB2 and c-erbB3 gene products (ERBB2and ERBB3) were demonstrated in all A.C.C. sections with some degree of straining. Tubular and cribriform patterns overexpressed particularly large amounts of ERBB2 and ERBB3. Strong staining was mainly demonstrated in tumor cells of the invasive area. These results suggested that overexpression of ERBB2 and ERBB3 is related to tumor differentiation and invasion in adenoid cystic carcinomas.

Adult↗
PubMed1996

Schwann cell differentiation of modified myoepithelial cells within adenoid cystic carcinomas and polymorphous low-grade adenocarcinomas: clinicopathologic assessment of immunohistochemical staining.

Adenoid cystic carcinomas and polymorphous low-grade adenocarcinomas have a known propensity for perineural invasion. Although modified myoepithelial cells have been shown to possess characteristics of a variety of cell types, they have not yet been found to mimic nerve tissue. Histologic evidence of Schwann cell differentiation would suggest the pathophysiologic mechanism by which these tumours exhibit neurotropism. An archival study of 41 specimens was performed to evaluate the Schwann cell staining properties of adenoid cystic and polymorphous low-grade adenocarcinomas using antibodies to S-100 protein, GFAP, neuron-specific enolase, and using a solochrome stain. Charts were reviewed to assess correlations between immunohistochemical and histochemical staining properties and various clinical parameters. The findings strongly suggest that neuronal differentiation does occur within these tumours. Furthermore, it was determined that solochrome positivity confers a significantly less favourable disease-free interval in these neoplasms. This new finding was highly statistically significant and has potential implications in the determination of prognosis for patients with these tumours.

Adenocarcinoma↗
PubMed1995

[Adenoid cystic carcinoma of the larynx, trachea and thyroid].

The aim of this article was to describe rarely occurred carcinoma adenoides cysticum located in the larynx, trachea and thyroid. Epidemiology, clinical course and medical therapy was demonstrated. In reported case concerning 65-year old woman early bilateral paresis of vocal folds was observed as results of the perineural infiltration. That caused sudden laryngeal dyspnea. It is important to pay attention on local extensiveness of neoplasm. Besides changes in larynx, neoplastic infiltration was found in trachea, preesophageal tissues and right lobe of thyroid. For above reasons there is no possible to exclude thyroid as a primary tumor of carcinoma adenoides cysticum.

Aged↗
PubMedDate not supplied

Adenoid cystic carcinoma of the cervix in a young patient.

Adenoid cystic carcinoma of the cervix is a rare disease. It usually occurs in an elderly age group. A case who presented at a younger age (30 years) is being reported. The chief complaint was excessive vaginal bleeding for 2 months. Per vaginum examination revealed a growth. She was staged FIGO IIIb. She was treated with radical radiotherapy. Disease regressed slowly and complete local response appeared after six months of treatment. Presentation of adenoid cystic carcinoma in younger age group and effect of radiotherapy in advanced stage is reviewed.

Adult↗
PubMed1996

[Very rare case of adenoid cystic carcinoma of the hypopharynx].

We experienced a case of adenoid cystic carcinoma (cribriform type) of the hypopharynx treated with radiation followed by total laryngectomy and bilateral radical neck dissection. There have been no reports of adenoid cystic carcinoma of the hypopharynx in the last 30 years. In this case, the primary tumor and lymph node metastases, of the neck responded well to radiation therapy. Residual disease of the primary tumor and lymph node metastases, after a dose delivery of 50 Gy, were removed by radical surgery.

Carcinoma, Adenoid Cystic↗
PubMed1996

Rapid proliferation of B cells from adenoids in response to Epstein-Barr virus infection.

EBV is a human tumor virus that is associated with different types of tumors. A unique feature of EBV is its capability to infect and immortalize human B cells both in vivo and in vitro. In cell culture, this progress is termed immortalization and infected B cells grow out to permanent, so-called lymphoblastoid cell lines. During our experiments, we observed that B lymphocytes derived from adenoids are infected efficiently by EBV and proliferate much more rapidly than any other known type of B cell. High concentrations of adhesion molecules and of CD21, the EBV receptor, present on these cells may account for this phenomenon. Adenoid B cells may therefore represent a particular subpopulation of preactivated B lymphocytes that can greatly simplify and enhance the production of lymphoblastoid cell lines for, e.g., antigen-presenting cells for gene therapeutic approaches and similar applications.

Adenoids↗
PubMed1996

Nasopharyngeal adenoid cystic carcinoma: five new cases and a literature review.

OBJECTIVE: Nasopharyngeal adenoid cystic carcinoma (NACC) is a rare tumour, and its mainstay treatment is different from adenoid cystic carcinoma arising from another head and neck region. In this study, we analyzed 20 cases of NACC with complete clinical information, 5 from Chang Gung Memorial Hospital and 15 from the literature review. RESULTS: The time interval between first symptom and treatment ranged from 2 weeks to 8 years, with a median of 24 months. Compared with usual nasopharyngeal carcinoma, NACC has higher incidence of cranial nerve involvement (55%) and lower incidence of cervical adenopathy (15%). All patients were treated by radiotherapy and 6 patients received surgical treatment. The 5- and 10-year overall survival rates were 78% and 49.5%, respectively. Seven patients developed metastasis to lung or bone. After a minimum of 5 years' follow-up, the local control rate was 45.5% in patients receiving radiation dose > 70 Gy, and 28.6% in those receiving dose < or = 70 Gy, suggesting higher radiation dose is necessary to achieve better local control in NACC.

Adult↗
PubMed1996

[Adenoid cystic carcinoma in patients in the ENT Department of the K. Marcinkowski University of Medical Sciences in Poznan in years 1980-1995].

In the years 1980-1995 60 patients with adenoid cystic carcinoma in the head and neck of different localization were treated at the Department of Otolaryngology. Majority of the tumors originated of the major salivary glands was parotid gland (24 cases). The most common location among the tumor of the minor salivary glands was the palate (5 cases). The tumors arising from others mucous glands, most frequently has located in the maxillo-etmoideal complex (12 cases). The authors stress diagnostic difficulties, the necessity of a proper selection of the surgical method and postoperative radiotherapy, describing the treatment results in the patients. Radical surgical procedure of the adenoid cystic carcinoma yields optimal local control and survival rates.

Adult↗