Search PubMed⌕ Search

SEARCH · Search PubMed

Results for “learning”

Search indexed PubMed citations on genomics, clinical trials, systematic reviews and public health. Explore titles, authors and supplied subject terms, then open the PubMed record.

Quote a phrase for an exact phrase match. Source license links do not imply unrestricted reuse.

At least 739 records · Page 41Linked to original sources
PubMed1993

Principles for learning single-joint movements. II. Generalizing a learned behavior.

The previous paper in this series showed that changes both within and between experimental sessions can be understood in the framework of the dual-strategy hypothesis of motor control, with a modification sometimes required for the timing of the antagonist muscle. The present paper extends these findings by determining how practicing movements at one distance generalizes to changes in performance at other distances. Five subjects made elbow flexion movements over five different distances (pretest). They then performed 1400 movements (seven sessions of ten blocks of 20 trials) at only one of those distances. The subjects then repeated the flexion movements over the five different distances (posttest). On the posttest, subjects decreased their average movement time by 20 ms. In addition, their movements became less variable. The electromyographic pattern of the faster movements was characterized by a more rapidly rising electromyogram, for three of the subjects, and an antagonist latency that decreased.

Adult↗
PubMed1976

Effects of nicotine on discrimination learning, consolidation and learned behaviour in two inbred strains of mice.

DBA/2J and C57BL/6J mice were injected with nicotine, and tested in a Y water maze in two procedures: the L procedure, coresponding to innate behavior, in which the animals must swim towards the light, and the D procedure, corresponding to the acquisition of a new pattern of behavior, in which they must swim toward the dark. Three sets of experiments were carried out: 1. In the pre-trial experiments, nicotine administration improved the innate tendencies of both strains, while the acquisition of a new behavior was facilitated in the C57 and impaired in the DBA mice. 2. In the post-trial experiments (D procedure), nicotine administration induced clear facilitating effects on the consolidation processes of the C57, while impairing these processes in the DBA strain. 3. The only effect evident, following nicotine administration, before the highest doses were reached, in the trained mice of both strains, was a performance impairment of the DBA mice trained in the L procedure.

Animals↗
PubMed1994

Matrix learning: an innovative development in large group experiential teaching and learning.

The article describes an innovative method of large group teaching that seems appropriate to the aims of higher education and especially well-suited to nursing and social work programmes. The author offers a brief rationale for the approach, which is illustrated with reference to the author's experience of using it with a large (64) group of social work students. Issues are raised for further research and developmental testing.

Education, Nursing↗
PubMed1995

Phosphorylation changes following weakly reinforced learning and ACTH-induced memory consolidation for a weak learning experience.

The formation of a protein synthesis-dependent long-term memory stage in day-old chicks trained on a passive discriminated avoidance task has been shown to occur only with an adequate level of reinforcement, and is preceded by a significant change in the phosphorylation state of the forebrain synaptosomal membrane protein GAP43 protein. In the present study, it is shown that weakly reinforced training did not lead to formation of a long-term memory stage or to any change in phosphate incorporation into forebrain P2M protein bands. However, administration of ACTH immediately posttraining led to both the formation of the long-term memory stage and a preceding significant increase in the phosphorylation of GAP43. These findings are consistent with the view that a reinforcement-dependent neurohormone-mediated change to the phosphorylation of this synaptosomal membrane protein may be implicated in the triggering of long-term memory consolidation.

Animals↗
PubMed2005

Learning by doing versus learning by thinking: An fMRI study of motor and mental training.

Previous studies have documented that motor training improves performance on motor skill tasks and related this to altered functional brain activity in cerebellum, striatum, and frontal motor cortical areas. Mental training can also improve the performance on motor tasks, but the neural basis of such facilitation is unclear. The purpose of the present study was to identify neural correlates of training-related changes on a finger-tapping task. Subjects were scanned twice, 1 week apart, with fMRI while they performed two finger-tapping sequences with the left hand. In-between scans, they practiced daily on one of the sequences. Half of the participants received motor training and the other half received mental training (motor imagery). Both training procedures led to significant increases in tapping performance. This was seen for both the trained and the untrained sequence (non-specific effect), although the gain was larger for the trained sequence (sequence-specific effect). The non-specific training effect corresponded to a reduction in the number of activated areas from an extensive set of brain regions prior to training to mainly motor cortex and cerebellum after training. The sequence-specific training effect involved the supplementary motor area and the cerebellum for motor training and visual association cortex for mental training. We conclude that gains following motor and mental training are based on distinct neuroplastic changes in the brain.

Adult↗