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PubMed1994

High speed pattern matching in genetic data base with reconfigurable hardware.

Homology detection in large data bases is probably the most time consuming operation in molecular genetic computing systems. Moreover, the progresses made all around the world concerning the mapping and sequencing of the genome of Homo Sapiens and other species have increased the size of data bases exponentially. Therefore even the best workstation would not be able to reach the scanning speed required. In order to answer this need we propose an algorithm, A2R2, and its implementation on a massively parallel system. Basically, two kinds of algorithms are used to search in molecular genetic data bases. The first kind is based on dynamic programming and the second on word processing, A2R2 belongs to the second kind. The structure of the motif (pattern) searched by A2R2 can support those from FAST, BLAST and FLASH algorithms. After a short presentation of the reconfigurable hardware concept and technology used in our massively parallel accelerator we present the A2R2 implementation. This parallel implementation outperforms any kind of previously published genetic data base scanning hardware or algorithms. We report up to 25 million nucleotides per scanning seconds as our best results.

Algorithms↗
PubMed1995

Development and implementation of an expert information system (BRITE) used in technical support of medical diagnostics customers.

We developed BRITE (Bringing Resources and Information to Employees), an expert information retrieval system, for problem solving and retrieving technical product information. Specialists in our Technical Assistance Center (TAC) use the BRITE system on a Pentium workstation to access information in < 3 s. Manuals, technical bulletins, parts lists, and administrative tools such as word processing and network fax are available electronically. The system allows consistent troubleshooting and definition of customers' problems by TAC specialists. BRITE seamlessly integrates expert system, document retrieval, and relational database technologies; the system runs on a token ring local area network, which is part of a Ciba Corning Diagnostics wide area network. Information received over the wide area network is used to develop and update BRITE daily. BRITE is kept current by input or troubleshooting and new applications from TAC specialists.

Chemistry, Clinical↗
PubMed1993

Computerization: the future of dental practice management.

Although computers are currently used in many dental offices, they are often simply PCs used for word processing or billing. There are some clinical dental computer systems in use, but, in the past, software limitations kept these systems from being integrated into practice management solutions. Dental computer systems in the future will combine clinical and practice management information, as well as marketing information, for optimal patient care with practice growth as a benefit.

Humans↗
PubMed1994

[Contribution of positron-emission tomography to the study of language].

Language is the most evolved and complex of cognitive functions. During recent years, its study has largely benefited from new medical imaging technologies among which positron emission tomography (PET), allowing for direct observation of in vivo human brain activity. This paper reviews some of the important advances in the understanding of single-word processing provided by PET, integrating them in the context of other fields of investigation such as cognitive neuropsychology. It also points out the limitations of the technique and some of its recent developments, opening the way for further comprehension of language processing.

Brain↗
PubMed1994

Computerized databases for emergency care: what impact on patient care?

A field-based evaluation is conducted of a Clinical Computerized Information System (CCIS). Following training, the use of the CCIS database, word processing and other programs by thirteen full-time practicing emergency physicians in two urban emergency departments of a University-associated teaching hospital was studied over a one-year period. A tracking program automatically logged frequency and duration of use by the physicians, and user satisfaction was assessed by a reliable and validated questionnaire instrument. Based on utilization data and verbal reports of these physicians, CCIS database searching was not only found to be easy-to-learn but was readily accessible during emergency shifts. Individual physicians were found to perform an average of 3.5 searches per month lasting a mean search time of 8 min. Positive notes about the CCIS system included ease-of-use, accuracy of data, accessibility of system, and value of output while negative perceptions included a lack of integration with other systems, a lack of system completeness, and a high subscription cost. It was suggested that a less costly telephone link to a high-volume Centre would be desirable in actual implementation of the system.

Attitude of Health Personnel↗
PubMed1994

Interface for the documentation and compilation of a library of computer models in physiology.

A software interface for the documentation and compilation of a library of computer models in physiology was developed. The interface is an interactive program built within a word processing template in order to provide ease and flexibility of documentation. A model editor within the interface directs the model builder as to standardized requirements for incorporating models into the library and provides the user with an index to the levels of documentation. The interface and accompanying library are intended to facilitate model development, preservation and distribution and will be available for public use.

Computer Simulation↗
PubMedDate not supplied

An intro to the Internet, Part III, the Internet and other online services.

Although the use of computer for word processing and spreadsheet analysis is widespread, other less well-known uses can also increase efficiency and productivity. In this bimonthly column, Dr. Nicoll discusses a variety of computer applications to help the nurse executive catch up, keep up, and get ahead.

Computer Communication Networks↗
PubMedDate not supplied

Desktop publishing: a useful tool for scientists.

Desktop publishing offers features that are not available in word processing programs. The process yields an impressive and professional-looking document that is legible and attractive. It is a simple but effective tool to enhance the quality and appearance of your work and perhaps also increase your productivity.

Computer Graphics↗
PubMed1994

Medical office automation integrated into the distributed architecture of a hospital information system.

Patient histories, discharge summaries, and medical consultant reports are made up of written texts. Therefore, the gathering and archiving of these texts in machine-readable form has many characteristics of computer-based medical records. In Geneva, approximately 1,540 PCs are connected to the Hospital Information System DIOGENE 2, with the possibility of accessing all the functions offered by the system without losing any of their MS-DOS word processing capabilities. The UNIDOC system, presented in this paper, takes all these features into account, a real marriage of technologies between the MS-DOS environment and the distributed client-server architecture. The INGRES database management system supports the entire archiving process of the medical patient texts, structured by prelabelled paragraphs and automatically indexed. Both the quality and accessibility of the records are enhanced, while the archiving capacity is neither too limited nor too expensive.

Archives↗
PubMed1993

Transformation of sequence data into geometric symbols.

To overcome the monotony of identifying specific patterns in a sequence or mutations in their alignment, transformation of sequence data into geometric symbols was previously suggested. I suggest a simple, improved method for accomplishing this transformation using the search and replace function available with word processing programs. This strategy a) enables facile transformation and back-transformation of the preexisting sequence and alignment data, which eliminates the manual entry of sequence, b) can be efficiently applied to amino acid sequences and their alignment data to identify the presence of specific motifs or repeat units and c) allows the use of any ASCII character for a given transformation, thus providing the flexibility to focus on a given unit of the sequence. A WordPerfect macro function has been provided along with the explanation of strategy for use with other programs.

Amino Acid Sequence↗
PubMed1993

Surgical pathology report in the era of desktop publishing.

Since it is believed that "a picture is worth a thousand words," incorporation of computer-generated line art was used as a adjunct to gross description in surgical pathology reporting in selected cases. The lack of an integrated software program was overcome by using commercially available graphic and word processing software. A library of drawings was developed over the last few years. Most time-consuming is the development of templates and the graphic library. With some effort it is possible to integrate graphics of high quality into surgical pathology reports.

Anatomy, Artistic↗
PubMed1995

Lowering physician hospital resource consumption using low-cost low-technology computing.

Anderson Area Medical Center physicians have been provided disease and procedure specific profiles of their practice experience for more than five years. For four years, physicians were provided reporting, in a variety of formats, detailing their clinical outcomes and consumption of hospital resources in treating patients with acute myocardial infarction (AMI), pneumonia, cholecystectomy, stroke, congestive heart failure (CHF), and total hip replacement. For the past eighteen months physicians have been provided a uniform format of monthly physician-specific reporting for stroke, AMI, pneumonia, diabetes, CHF, cholecystectomy, total hip replacement, newborn delivery, angina, and hernia repair. Using only a modest PC platform with database, word processing, and graphics programs operating in a DOS environment, an effective disease/procedure reporting program is provided to medical staff with 3 person-days of effort per month.

Computer Systems↗
PubMed1986

Microcomputers and biologists.

Microcomputers have now become a working tool of the biologist. This article explores some of the consequences of this revolution both in terms of the skills and working habits needed and of the range of uses which have been found. The primary consequence is that biologists must learn how to become computer managers. This does not mean learning BASIC and computer architecture, though this will usually prove valuable, but that we must be able to grasp from the flood of sales literature and computer specialists what tasks can or should be undertaken with the aid of microcomputers. Secondly it means being able to choose and maintain the right machinery for the tasks needed. An overview of applications shows four main areas of use. 1) The standard packages where one can expect the computer manufacturer to provide a complete working system. These are word-processing, database reference systems, spreadsheet calculations, graphics production and communications. 2) Specialist scientific programs such as statistics, data processing and model making. 3) The use of the microcomputer as a laboratory instrument for control or measurement. 4) Educational applications. Each of these areas has separate, often conflicting, requirements which can only be balanced by the user.

Audiovisual Aids↗
PubMedDate not supplied

Integration of laptop computer technology into an undergraduate nursing course.

An evaluative study was done to determine the effects of laptop computer use on baccalaureate nursing students' attitudes toward computers, computer knowledge, and computer skills. Students in the experimental group (n = 20) received laptop computers and 9 hours of computer instruction. They were encouraged to use the laptop computers for e-mail, library searches, and word processing. The comparison group (n = 18) completed the same assignments in the usual manner. Students had positive attitudes toward computers both pretest and posttest with no significant increase or difference between the two groups. There was no significant difference between the two groups in computer knowledge outcomes; however, the experimental group had statistically significant gains in computer skills. Results of this study suggest that the integration of laptop computer technology into the undergraduate nursing curriculum can be an effective way to increase students' computer skills while maintaining positive attitudes toward computers in nursing.

Adult↗
PubMed1996

New Zealand general practice computerisation; attitudes and reported behaviour.

AIMS: To gather information from general practitioners regarding aspects of computerisation including whether certain tasks should be computerised and whether those tasks were in fact computerised at their practice. METHODS: Five hundred general practitioners randomly selected throughout New Zealand were sent a postal survey in May 1995. Results were then collated and analysed. RESULTS: The response rate was 54% (268). Computerisation is becoming a necessity according to 85% of responders and a computer was used for at least one task by 84% of doctors. Computer use during consultation interfered unduly with doctor-patient communication according to 43% of responders. Privacy issues had not been dealt with adequately for 33% of responders. The five most frequently computerised tasks were; maintaining an age-sex register (81% of responders), recalls (80%), administration (77%), making appointments (50%) and word processing (49%). The number of doctors in a practice and responders' RNZCGP membership status appeared predictive of task computerisation. Responders' gender, year of graduation and their membership on the Indicative General Practitioners Register were not statistically significant factors for determining attitudinal and behavioural responses. CONCLUSIONS: The low response rate limits generalisation but the trends in the results are important. Reported tasks with greatest potential for computerisation were doctor education; checking drug interactions/contraindications; patient education; tasks relating to interfacing with laboratories; and database enquires of patients. Significant concerns among responders were perceived interference with doctor patient communication and privacy issues. Eighty-four percent of responders use the computer for at least one task.

Adult↗
PubMed1997

Lexical-semantic organization: evidence from aphasia.

The emerging field of clinical neuroscience requires the combination of diverse theoretical and methodological approaches to the study of brain function. The study of neurogenic language disorders has played a central role in the development of models of language/brain relationships. These contributions are reviewed with regard to the study of word processing impairments in aphasia, where data from brain-damaged patients has been used to guide the development of models of lexical/semantic organization. It is argued that the study of aphasic patients will continue to occupy a central role in both neuroscience and clinical research as new technologies are developed for functional brain imaging and as theoretically driven treatments for aphasia are designed and tested.

Aphasia↗
PubMed1997

The pathologist's workstation.

To leverage the time and expertise of the pathologist, a comprehensive workstation is a useful tool. Because the practice of pathology is so diverse, however, there is no one standard for what constitutes a workstation. The author reviews the several elements and components which must be included (access to your LIS, word processing, electronic mail, Web browser, literature search), and also reviewed are the many more which may be included, depending on the specialized needs of the practitioner (statistical analysis, ROC curves, image analysis, voice synthesis). It is, however, up to the pathologist to determine which of these components are required and to assemble them in as seamless a manner as possible.

Computers↗
PubMed1997

Family physicians' preferences for computerized decision-support hardware and software.

BACKGROUND: While computers are now widely used by family physicians for billing and patient registration purposes, their use as decision-support tools is still quite limited. The purpose of this study was to determine the current use of computer hardware and software by family physicians, and the characteristics these physicians desire in computerized decision-support hardware and software. METHODS: A cross-sectional survey of a random sample of 250 Michigan family physicians was undertaken in mid-1995. These physicians were asked about their current use of a variety of computer hardware and software. They were also asked to rate the value of different kinds of decision-support information potentially available by computer. The survey instrument also gathered the family physicians' preferences for design factors (both hardware and software), such as the size of a computer, the time needed to access information, and the frequency of updates. RESULTS: Word processing on desktop computers and hospital information systems are the most widely used computer applications by family physicians. Physicians are most interested in computer-based information on drugs, storage and generation of patient education materials, and accessing treatment recommendations. Most feel that semiannual or annual updates of information are adequate, and would like a uniform interface. A high percentage of physicians (84.5% of all physicians and 94.1% of younger physicians) stated that they would consider carrying a handheld computer. CONCLUSIONS: There is significant interest in several types of clinical decision-support software. Based on the results of this study, such software should have following characteristics: (1) be available for handheld as well as networked and desktop computers, (2) include drug information (particularly warnings, interactions, and side effects), (3) include overviews of treatment recommendations, (4) include patient education materials, and (5) have a uniform user interface and be updated at least annually.

Adult↗