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PubMed1986

Improving the accuracy of intercensal estimates and postcensal projections of the civilian noninstitutional population: a parameterization of institutional prevalence rates.

The authors first note that current official U.S. population estimates and projections are based on the assumption that certain characteristics of the institutionalized population remain constant between censuses. The article "examines the empirical validity of this assumption by using data from the decennial censuses for 1940-1980 and, in light of substantial decade to decade changes in the age patterns of the institutional proportions for sex- and race-specific populations, seeks to develop alternative methods." As part of these alternative methods, "parametric curves are fit to the age-specific institutional proportions for each population for each decade. A study of the observed historical variation in the parameters of these curves then leads to some suggestions about how their shapes can be estimated between censuses and projected beyond the latest available census to provide more accurate estimates and projections of the civilian noninstitutional population." This is a revised version of a paper originally presented at the 1984 Annual Meeting of the Population Association of America (see Population Index, Vol. 50, No. 3, Fall 1984, p. 439).

Age Factors↗
PubMedDate not supplied

The Population-Focused Analysis Project for teaching community health.

New instructional methodologies that foster student inquiry, critical thinking, accountability, group work, and self-mastery skills must be created to meet the challenges of modern community health nursing. Bold steps need to be taken to examine current nursing curricula and institute innovative teaching-learning methods to achieve these outcomes. Designing a unique way of providing clinical practice in community assessment is one step toward achieving these goals. The purpose of this article is to share the development, implementation, and evaluation of the Population Focused Analysis Project (PFAP). This new approach to community assessment for baccalaureate nursing students links theory and clinical practice and provides students with an opportunity to learn about and implement the core functions of public health in relation to a selected population.

Attitude of Health Personnel↗
PubMed1993

[Social class and cardiovascular risk factors in Italian-speaking Switzerland: results of the first Swiss population study MONIKA Project 1985-1986].

The relationship of social class and prevalence of risk factors for cardiovascular diseases was investigated within the Swiss MONICA-project, a cross sectional study of the Swiss-Italian population started in 1985/1986. A representative sample of 984 men and 1014 women ages 35 to 64 was selected, the response rate was 78%. Social class was measured by two indicators, occupational status and education. A significant trend was found in age standardized analysis with higher mean blood pressure and body mass index in lower social classes (p < 0.001). When other confounders for cardiovascular diseases were considered in a multiple regression model, the predictive power of social class was moderate. A significant inverse relationship of cardiovascular risk factors and social class was only found for body mass index (both sexes) and exercise in women which was directly related to higher social class and education. No relationship was found for lipids (cholesterol, HDL-cholesterol), blood pressure and smoking in both sexes. Risk factors for cardiovascular diseases beside obesity do not seem to cluster in lower social classes within the Swiss-Italian population.

Adult↗
PubMed2005

Low incidence of acute urinary retention in the general male population: the triumph project.

OBJECTIVE: To describe the incidence of acute urinary retention (AUR) in the general male population and in a population of men newly diagnosed with lower urinary tract symptoms suggestive of BPH (LUTS/BPH). METHODS: We performed a retrospective cohort study in the Integrated Primary Care Information (IPCI) database, a GP research database in The Netherlands, during the period 1995-2000. All males, > or =45 years, without a history of AUR or radical cystectomy were included in the study. In addition, we followed a sub-cohort of men, newly diagnosed with LUTS/BPH. AUR was defined as the sudden inability to urinate, requiring catheterization. RESULTS: Amongst 56,958 males with a mean follow-up of 2.8 years, 344 AUR cases occurred (incidence rate 2.2/1000 man-years) of whom more than 40% were precipitated. AUR was the first symptom of LUTS/BPH in 73 (49%) of the 149 AUR cases that occurred in men newly diagnosed with LUTS/BPH. The risk of AUR was 11-fold higher in patients newly diagnosed with LUTS/BPH (RR 11.5; 95%CI: 8.4-15.6) with an overall incidence rate of 18.3/1000 man-years (95%CI: 14.5-22.8). CONCLUSIONS: The incidence rate of AUR is low in the general population but substantial in a population of men newly diagnosed with LUTS/BPH. The incidence rate increases with age and AUR is precipitated in approximately 40% of all cases. Within the LUTS/BPH cohort, AUR is the first presenting symptom of BPH in 50% of all AUR cases.

Acute Disease↗
PubMed2004

Cataract surgery and subtype in a defined, older population: the SEECAT Project.

AIM: To describe the distribution of cataract subtypes present before surgery among a defined population of older, bilaterally pseudophakic individuals. METHODS: This was a cohort study of bilaterally pseudophakic individuals participating in the Salisbury Eye Evaluation (SEE), and their locally resident siblings. Subjects underwent slit lamp and retroillumination photography and grading using the Wilmer Cataract Grading System. For all individuals determined to be bilaterally pseudophakic, an attempt was made to determine for each eye the type(s) of cataract present before surgery, based on previous SEE photographs (for SEE participants) and/or medical records obtained from the operating ophthalmologist (for both SEE participants and their siblings). RESULTS: The mean age of 223 participants providing data in this study was 78.7 (SD 5.2) years, 19.3% of subjects were black and 60.1% female. The most common surgically removed cataract subtype in this population was pure nuclear (43.5%), followed by nuclear combined with posterior subcapsular cataract (PSC) (20.6%), and nuclear combined with cortical (13.9%); less common types were pure cortical (4.9%), pure PSC (4.5%), and PSC combined with cortical (2.7%). Factors such as sex and source of lens data (study photograph versus clinical record) did not significantly affect the distribution of lens opacity types, while PSC was significantly (p = 0.01) more common among younger people and nuclear cataract was significantly (p = 0.001) more common among white compared to black people. CONCLUSION: Epidemiological studies have suggested that the different subtypes of cataract are associated with different risk factors. As studies begin to identify new prevention strategies for cataract, it would appear likely that different strategies will be efficacious against different types of cataract. In this setting, it will be helpful to know which cataract types are most frequently associated with surgery. Among this older, majority white population, nuclear cataract showed a clear predominance among individuals having undergone surgery in both eyes. This may be contrasted with both clinic and population based studies of younger people, which have generally found PSC cataract to predominate.

Age Distribution↗
PubMed1995

Distinct projections of two populations of olfactory receptor axons in the antennal lobe of the sphinx moth Manduca sexta.

The central projections of olfactory receptor cells associated with two distinct types of antennal sensilla in the sphinx moth Manduca sexta were revealed by anterograde staining. In both sexes, receptor axons that arise from sexually isomorphic, type-II trichoid sensilla (and possibly some basiconic sensilla) project to the spheroidal glomeruli in the ipsilateral antennal lobe. Each axon terminates in one glomerulus. Axons from a limited region of the antenna project to glomeruli throughout the lobe, arguing against strict topographic mapping of antennal receptor cells onto the array of glomeruli. Axons of sex-pheromone-selective receptor cells in the male-specific type-I trichoid sensilla project exclusively to the sexually dimorphic macroglomerular complex (MGC). Axons from sensilla on the dorsal surface of the antenna are biased toward the medial MGC and those from ventral sensilla, toward the lateral MGC. Some receptor-cell axons branch before reaching the MGC, but their terminals are always confined to one of the two main glomerular divisions of the MGC, the cumulus and toroid. These findings confirm that primary-afferent information about pheromonal and non-pheromonal odors is segregated in the antennal lobe and suggest that there is a functional correspondence between particular olfactory receptor cells and specific glomeruli.

Animals↗
PubMed1997

Study of bone mineral density in lumbar spine and femoral neck in a Spanish population. Multicentre Research Project on Osteoporosis.

The aim of this study was to generate standard curves for bone mineral density (BMD) in a Spanish population using dual-energy X-ray absorptiometry (DXA), at both lumbar spine and femoral neck sites. The total sample size was 2442 subjects of both sexes aged 20-80 years, stratified according to survival rates, demographic distribution by local regions and sex ratio in the Spanish population. Subjects with suspected conditions affecting bone metabolism or receiving any treatment affecting bone mineralization were excluded. The study was carried out in 14 hospitals and bone density measurements were performed, using a QDR/ 1000 Hologic device. In the female population, the highest value for lumbar spine BMD was found within the 30-39 years age group, being significantly lower after the age of 49 years. In the male population, the highest values for lumbar spine BMD are found one decade earlier than in the female population and become significantly lower after the age of 69 years. The highest values for femoral neck BMD in men and women was found in the 20-29 year age group. Values for femoral neck BMD in the female population become statistically lower after the age of 49 years, while in the male population this effect was seen after the age of 69 years. Values for femoral neck BMD were higher in men than women at all ages.

Absorptiometry, Photon↗
PubMedDate not supplied

Assessment of hypertension levels control and management (hypertension "AUDIT" project). Study in a population of workers.

The hypertension AUDIT project (WHO) was used for the study of large populations of workers in two Romanian industrial centers, Slatina and Sibiu, constituted into two main groups. The objects of the study were: the detection of new cases of arterial hypertension (AH) and of their proportion as compared with older cases, the assessment of the quality of diagnosis control and treatment methodology as well as the estimation of the patient's attitude regarding the conditions of treatment and of the physician's knowledge and attitude regarding AH. Group I (Slatina) included 22,839 workers and the program was applied in 15,740 randomly chosen subjects. Group II (Sibiu) included 14,874 workers of whom 2,838 were randomly chosen for study. From a total of 606 (6.20%) subjects aged 35 to 64 years with AH in both groups, 494 (81.51%) were older cases and 112 (18.48%) were newly detected. The prevalence of AH was found to increase with age and to be higher in women aged 55 to 64 years. The treatment in older cases from both groups was considered effective in 232 cases (46.96%) (of which 26 (11.2%) with overtreatment) and insufficient in 262 (53%). The reasons alleged by the patients for the late detection of AH were the absence of symptoms and a casual interest for their state of health. The risk factors were systematically checked. Smoking was found in 30.36% of the subjects in group I and in 31% of those in group II. The use of diagnostic laboratory procedures was corresponding to the present recommendations. The nonpharmaceutic therapy was frequently recommended, especially reduction of salt consumption. Besides that, pharmaceutic treatment was indicated in most of the patients (63% in group I and 90% in group II). Diuretics (41.26% in group I and 75% in group II), and beta blocking drugs (35.3% in group I and 70% in group II) were the most frequently administered and in a lesser proportion vasodilators with central or peripheral action, calcium blockers, Rauwolfia and angiotensin conversion enzyme inhibitors. The consumer inquiry showed satisfactory compliance of patients, most of them took their tablets regularly, were satisfied with the medical assistance and preferred to consult the same physician. The data of the physician inquiry regarding diagnosis treatment of AH and professional training also proved satisfactory. The use of the AUDIT project has allowed a complex estimation of AH in the groups studied and will prove useful for a more efficient control of AH in the whole population.

Adolescent↗
PubMed1993

Guidelines for local research ethics committees: distinguishing between patient and population research in the Multicentre Research Project.

A multicentre population research study was undertaken, involving ethical approval from 28 local research ethics committees. The major problems encountered were delays, which fell into three categories: requests to complete separate application forms, delay in processing applications and additional requests for patient and consultant consent. We examine these sources of delay in the context of the recently published DoH guidelines for local research ethics committees. Our findings reveal that there is not only an absence of adequate guidelines for multicentre research studies but that the new guidelines for local research ethics committees fail to distinguish between patient research and the population study.

Ethical Review↗
PubMed1992

Effects of epilepsy on daily functioning in northern Ecuador: summary of findings of a population-based research project.

215 patients with epilepsy and 125 healthy controls were questioned on the effects of epilepsy on social functioning as part of a population-based study of epilepsy in Northern Ecuador. 144 of these patients and 98 of the controls were followed, over a period of 1 year during an intervention study and their response to treatment assessed. Economic, intellectual and social functioning were examined. In the patient group, function was affected in important areas, most clearly, work. The low opinion the community had of the intellectual and physical abilities of patients might affect a patient's own view of themselves and sometimes diminish their opportunity for development. At 12 months, as a result of treatment, a significantly lower level of patients reported effects on function in some areas, though control individuals' views of their functional impairment had not shifted to any extent. Moreover, despite improvement, more patients at 12 months acknowledged fear of seizures, especially their unpredictability, as a handicapping factor, particularly in working outside or away from home. This seems to indicate that even when seizures are controlled, for many patients, the uncertainties of the condition remain and continue to affect their view of their capabilities.

Activities of Daily Living↗
PubMed1992

Selective population chemotherapy among schoolchildren in Beheira governorate: the UNICEF/Arab Republic of Egypt/WHO Schistosomiasis Control Project.

Selective population chemotherapy using a single dose of praziquantel (40 mg per kg body weight), which was offered to 29,365 schoolchildren in Abu El Matameer and 40,241 in Abo Homos districts, Beheira governorate in the Nile delta, reduced the prevalence of schistosomiasis from 75.4% to 40.9% (reduction of 45.8%) and from 80.5% to 30.8% (reduction of 61.7%), respectively. Of those with only S. mansoni infection, 10.6% before treatment and 1.7% one year later had more than 800 eggs per gram of faeces. The prevalence of S. haematobium in Abu El Matameer was reduced from 35.4% to 7.4% after a single treatment. Infections with both S. mansoni and S. haematobium were reduced by more than 90% after one year. These reductions in prevalence and intensity of schistosomiasis in the face of continuing transmission and water contact augur well for the future role of chemotherapy in control programmes.

Adult↗
PubMed1991

Approximation for age-structured population models using projection methods.

"In this paper we present a class of rapidly convergent numerical schemes to solve the Sharpe-Lotka model equation from age-dependent population dynamics. This work is based on spline approximation techniques described by Banks and Kappel for functional differential equations. We provide a motivation for and description of a generalized problem which under suitable conditions is equivalent to the Sharpe-Lotka problem, we describe approximation in general which exploits the Hilbert space structure in which the generalized problem is set, and for a particular space of approximating functions we obtain estimates on the rates of convergence."

Age Factors↗
PubMed2005

Web-based screening for diabetic retinopathy in a primary care population: the EyeCheck project.

The objective of this study was to evaluate the feasibility of ATA category 2 Web-based screening for diabetic retinopathy in a primary care population in the Netherlands. A total of 1,676 patients in a primary care setting, with diabetes, without known diabetic retinopathy, and without previous screening by an ophthalmologist, were included between January 1 and December 31, 2003. Patients underwent a brief questionnaire and two field retinal photography. Photographs were independently read by two ophthalmologists. Outcome measures were gradability of the photographs, need for pharmacologic pupil dilation, assessment as suspect for presence of diabetic retinopathy, of neovascularization and of diabetic retinopathy, and agreement between graders. Of the population studied, 11.3% of patients required pupil dilation, average transmission time of images was 73 sec, 12.0% of patients had ungradable photographs, 10.4% of the patients with gradable photographs were assessed as "suspect for diabetic retinopathy," and 2.0% were assessed to need urgent referral. Red lesions were present in 3.5% and bright lesions were present in 1.6% of all gradable patients. Neovascularization of the disk was found in one patient. Type 1 patients had much higher rates of "suspect for diabetic retinopathy" (34.5%) than type 2 patients (9.4%). Interrater agreement kappa was 0.93. Web-based screening, using open source technology and uncompressed images, is feasible in a primary care setting, with a high rate of inter-rater agreement. Dilate-as-needed may be a sensible approach for retinal photography. The high incidence of "suspect for diabetic retinopathy" in type 1 diabetes patients illustrates that web-based diabetic retinopathy screening programs for these patients may detect diabetic retinopathy that would otherwise have gone undetected.

Diabetic Retinopathy↗
PubMed1999

New estimates and projections of the population cohabiting in England and Wales.

This article describes the derivation of a new set of population estimates of those cohabiting in England and Wales in 1996. As well as estimating the population cohabiting by age and sex, the estimates have also been made by legal marital status. The article then discusses new projections to the year 2021, based on these estimates.

Adolescent↗