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PubMed1997

The dangerous financial politics of AIDS "cocktail" therapies.

Political pressures by local AIDS activists are forcing some communities to redirect limited financial resources exclusively toward new drug therapies called protease inhibitors. These expensive and often reckless decisions threaten both the financial integrity of AIDS service organizations and the health of the public. The dangerous financial politics surrounding access to the new and complicated drug therapies for AIDS threaten to bankrupt local AIDS health service, create inescapable financial and legal liabilities, and may contribute to a worsening of the AIDS epidemic, causing the elimination of essential systems of prevention and care for the highest risk populations-adolescents and minority women.

Adolescent↗

PubMed1997

Human rights and the politics of risk and blame: lessons from the international reproductive health movement.

Recent debates about the "politicization" of public health obscure the ways in which epidemiological concepts of risk are routinely used in the legal and political systems to apportion blame and responsibility for poor health. This article uses the example of reproductive health and rights to argue that new understandings of the connection between socioeconomic conditions and poor health will only generate change when they are reframed into political claims and pressed by social movements. In this connection, human rights language, principles, and practice hold great potential for the US reproductive rights movement, which has sometimes been constrained by the narrow scope of court rulings.

Family Planning Services↗

PubMed1998

'No other logical choice': global malaria eradication and the politics of international health in the post-war era.

In 1955 the Eighth World Health Assembly voted to initiate a program for the global eradication of malaria. The global eradication of malaria represented a remarkable leap of faith. Many health authorities, both within and outside the Assembly, viewed eradication as at best fool hardy, and at worst, potentially disastrous. To understand why the World Health Assembly went ahead with a Global Eradication strategy, despite these concerns, it is necessary to examine the politics of international health and development in the post-war era. This political context shaped decisions about the adoption of DDT as a primary tool in the fight against malaria, as well as the adoption of the Malaria Eradication Program. It is equally important to understand how the advocates of an eradication strategy shaped arguments and developed support for their cause in the years leading up to the Eighth World Health Assembly meeting.

DDT↗

PubMed1998

[Political and economic aspects of heart transplantation].

Organ transplant, like any other area of modern medicine, has manifold implications for human values and ethics, while sociology, law, economics and politics are equally involved. A brief review is presented of the political and economic aspects of cardiac transplantation, covering a short overview of current Swiss legislation, the problem of organ allocation, limitation of transplant centres, restriction of transplant medicine to public hospitals, cost of transplant procedures and subsequent treatment, and costs generated by alternative options such as ventricular assist devices. Current transplant medicine is affected by a growing shortage of organs, despite the fact that organ transplantation is generally well accepted by the public. On the other hand, the steadily growing disproportion between the number of organs available and the overall number of potential recipients is a source of concern for transplant surgeons and the medical profession, as well as the community at large. To be able to face these significant problems, transplant centres should offer all aspects of treatment for heart failure. In particular, before cardiac transplant is offered to a patient, all aspects of more conservative treatment should be exhaustively discussed. The economic aspects of each type of transplantation are usually discussed, but the cost of a transplant procedure should be compared with that of conventional treatment. The increasing use of all currently available options (including mechanical and antiarrhythmic bridging) makes a critical confrontation with the economic implications necessary. Assumptions based on current literature suggest that heart transplant generates additional costs of approximately CHF 50,000 per year of extended life. The treatment of heart failure involves additional costs of CHF 20,000 per year, provided only a few hospitalizations are necessary. CHF 80,000 of the cost of a heart transplant is refunded. Medical treatment in the first year after transplant mainly includes immunosuppressive drugs, antibiotic and antihypertensive medication, involving additional costs of CHF 20,000. The future will require complete use of all conventional treatment modalities, recipient selection, strengthened social rehabilitation and a quality control database, as well as consensual recommendations and coordination in research, follow-up and basic treatment.

Costs and Cost Analysis↗

PubMed2000

Rehabilitation of olfaction after laryngectomy by means of a nasal airflow-inducing maneuver: the "polite yawning" technique.

OBJECTIVE: To develop a nasal airflow-inducing maneuver and apply it in the olfactory rehabilitation of patients who have undergone laryngectomy. DESIGN: Intervention study; before-and-after trial. SETTING: National cancer center. PATIENTS: Forty-four patients who underwent laryngectomy; 34 men and 10 women; mean age, 64 years (range, 42-80 years); mean time since surgery, 6 years (range, 8 months to 18 years). INTERVENTION: In a prospective clinical intervention study, we assessed the effectiveness of a nasal airflow-inducing maneuver ("polite yawning," ie, yawning with closed lips). Speech therapists trained the patients in the maneuver, and its effectiveness in inducing nasal airflow was checked with digital and water manometers. MAIN OUTCOME MEASURES: Olfactory acuity was assessed before and after the intervention by means of an odor detection test and a structured questionnaire concerning olfaction, taste, and appetite. Patients were categorized as "smellers" and "nonsmellers" on the basis of the results of the odor detection test and the present odor perception scale derived from the questionnaire. RESULTS: The nasal airflow-inducing maneuver could be taught to all patients, mostly in only one 30-minute therapy session. Fifteen of the 33 patients in the pretreatment nonsmeller category converted to smellers, for a success rate of 46% (P<.001). CONCLUSION: The nasal airflow-inducing maneuver (the "polite yawning" technique) allowed almost half of the patients to recover their sense of smell.

Adult↗

PubMed2002

Long-term results of olfaction rehabilitation using the nasal airflow-inducing ("polite yawning") maneuver after total laryngectomy.

OBJECTIVES: To study the long-term results of the nasal airflow-inducing maneuver (NAIM) as an olfaction rehabilitation tool after laryngectomy and to investigate the effectiveness of a new, simpler odor detection test (ODT) called the smell disk test (SDT), or Zürcher Geruchstest. DESIGN: Intervention study. SETTINGS: National cancer center. PATIENTS: Forty-one laryngectomees who received olfaction rehabilitation training with the NAIM 4 months to 2 years earlier. This so-called polite yawning maneuver creates an "underpressure" in the oral cavity, which, in turn, generates a nasal airflow that enables odor molecules to again reach the olfactory epithelium. MAIN OUTCOME MEASURES: Olfaction acuity testing with a standard ODT, along with a questionnaire, providing a subjective olfaction score (present odor perception scale [POPS]), and the SDT, as well as assessment of the patients' correct execution of the NAIM by speech-language pathologists on video recordings made during odor testing and long-term assessment of olfaction acuity. RESULTS: The correlation between the previously used ODT-POPS combination and the SDT was kappa = 0.56 (P<.001). Based on these results, we preferred to use the much simpler SDT instead of the laborious combination of the ODT-POPS. Based on the SDT results, 19 (46%) of the 41 laryngectomees were "smellers" and could be considered normosmic. There was a significant relationship (P =.03) between the patient's correct execution of the NAIM and whether or not the laryngectomee was a smeller according to the SDT. CONCLUSIONS: The effectiveness of the NAIM, or so-called polite yawning technique, for the rehabilitation of olfaction in individuals who have undergone total laryngectomy was reconfirmed. Long-term olfaction rehabilitation was achieved in about 50% of the patients, but more intensified training may be needed to increase the percentage of successfully rehabilitated individuals. The SDT is an effective and simple test for the assessment of olfaction acuity after laryngectomy.

Adult↗

PubMed1993

The politics of closing state mental hospitals: a case of increasing policy gridlock.

There are political and administrative barriers to closure of the remaining state mental hospitals. Some of these barriers owe their existence to the current lack of community-based alternatives for the care and treatment of the severely mentally ill. In addition, uncertainty of the future funding and regulatory commitment of state governments to community programs contributes to an unwillingness by influential groups to recommend or implement closure. Finally, other barriers include rigid budgetary processes, the self-interest of public employees, and the lack of consensus in the decision making process. The result is that even when the case for closure of a state mental hospital is convincing, these political and administrative factors can cause "policy gridlock." This article describes how such policy gridlock occurs and offers several suggestions as to how it can be prevented.

Community Mental Health Centers↗

PubMedDate not supplied

Methodological and political issues in clinical pharmacology research by the year 2000.

Parallel groups in a large, multicenter, phase III "pivotal" randomized clinical trial (RCT) with clinically relevant end-points are seen by the medical community as the "gold standard" of clinical research. However, there are limitations, some methodological and others political. The main one is the external validity of the method because a treatment, as studied in RCTs, does not necessarily reflect how it is used in clinical practice. Also, the method, as it stands, is not really predictive of the success in a particular patient of a certain intervention studied in a trial. To overcome these methodological drawbacks, different options have been implemented. The most important ones are: (1) the performance of pragmatic RCTs intended to address effectiveness rather than efficacy; (2) meta-analysis; and (3) the use of observational studies, with or without a comparison group. Recent experience has shown that type-A adverse drug reactions (ADRs) related to a specific class of drugs have been successfully characterized throughout cohort- or population-based case-control studies, whereas the evidence linking a specific drug entity to a type-B ADR, apparently severe enough to withdraw the drug from the market, has come mainly from case reports or case series. Other limitations of the RCT are more of a political nature. These large "pivotal" trials are mostly sponsored by the pharmaceutical industry, and to guarantee the scientific and ethical integrity of data produced, they are performed following standard operating procedures (SOPs) and good clinical practice (GCP) guidelines. Sometimes industry is not interested in sponsoring trials; thus, RCTs performed are in practice highly biased because of their potential economical profits. Furthermore, applying SOPs and GCPs is expensive and difficult to implement, and it is hard to find funding in public institutions. As a result, there is an urgent need to create a network of independent, skilled groups interested in sponsoring and performing institutional RCTs following "user friendly" GCP when the profits are low, but scientific interest high.

Forecasting↗

PubMed1997

Specific Contributions of Politics, Economics, and Toxicology in Setting Socially Consensual Limit Values

/ Limit values are legal limits for the concentrations of substances in the environment. They must be agreed upon in a consensual procedure between science, economics/technology, and political forces. This is a crucial political precondition for their social acceptance. The arguments put forward to justify their expediency and numerical level are based not only on risk-benefit considerations but also on the aspect of the technical avoidability of direct and indirect exposure. The critical assessment of the direct benefit of specified exposures falls within the responsibility of economics/technology, whereas criteria for their potential adverse effects (direct and indirect) are provided by medicine/biochemistry and/or ecology. Within this concept, the avoidance of nonbeneficial-even if not openly adverse-exposure is the essential aim of environmental hygiene and should be promoted by politics/science. In general, society or segments thereof reject adverse, accept beneficial, and tolerate unavoidable exposure. Conflicts of interest arise when different groups of society simultaneously define a given exposure as being adverse, beneficial, and unavoidable. Therefore, from the viewpoint of society as a whole, an optimal exposure lies as far as reasonably achievable at a level lower than known or plausible adverse effect thresholds (as defined by toxicology or ecology). This optimal level of exposure must be determined using a transparent and, hence, public procedure.KEY WORDS: Legal limit values; Benefit threshold; Social acceptance; Social tolerability; Adverse effect threshold; Avoidable exposure; Tolerance threshold; Environmental hygiene

Journal Article↗

PubMed1983

Planning and politics of resource allocation for primary health care: promotion of meaningful national policy.

Securing resources for primary health care (PHC) involves consideration of the entire health sector: the higher levels of the health service as well as the primary level, and the private and/or social security sub-sectors as well as the government service. Reshaping resource distribution is less a redistribution of existing resources than the allocation of new resources in accordance with PHC priorities. In this the planning of future current costs is a crucial element and requires a budgetary system that identifies expenditures by geographical area and level of care. Resources should be allocated geographically to reduce health care inequalities through the provision of an appropriate mix of different levels of care. Central resource planning and local health care programming (with 'dialogue' between the two) should be the basic planning division of labour, which largely resolves the so-called top-down/bottom-up dichotomy. The private medical sub-sector exerts economic, ideological and political influences on the public health service. Compulsory health insurance schemes can have some similar effects. Success of a PHC policy requires that governments adopt a holistic approach to the health sector. The allocation of health care resources on the bases of need and equity, as opposed to demand, is a political decision. The establishment of a national PHC policy backed up by adequate resources involves a specific politico-technical exercise with four components: research, planning, policy formulation, and government policy decision-making. The resource planning method, based on social epidemiology, is contrasted with conventional health planning methods, based on epidemiology. The articulation of these two approaches is discussed in terms of WHO's Managerial Process for National Health Development.

Costs and Cost Analysis↗

PubMed1990

International politics and primary health care in Costa Rica.

Costa Rica's internationally-renowned rural health program exemplifies the principles put forth by the 1978 Alma Ata Declaration on Primary Health Care with one exception: the government has not succeeded in achieving active community participation in health. This paper uses a historical and political-economic perspective to explain why the Costa Rican government failed in its efforts to enhance community participation after Alma Ata. International agencies have been closely involved in the design and implementation of rural health services in Costa Rica since the early 1900s, yet community participation did not figure in these programs until the mid-1970s. The demise of community participation in the early 1980s is attributed to a combination of factors including partisan conflicts, social class conflicts, interest group politics and, particularly, to the shifting priorities of international health and development agencies.

Community Health Services↗

PubMed1991

Tobacco, politics and economics: implications for global health.

This paper examines the expanding presence of multinational cigarette companies into almost every country in the world, and discusses the health implications of this global penetration. Cigarettes deserve special attention because tobacco is the only legally available consumer product that is harmful to one's health when used as intended. A temptation exists to blame governments for the existence of health-threatening products within their borders. However, this paper illustrates the extent to which extra-national forces influence domestic policies and circumstances. Cigarette smokers are often blamed for their lethal habit, despite billion-dollar promotional schemes which attract people to smoking, obscuring the harmful consequences of consuming a highly addictive drug. Multinational cigarette companies are increasingly targeting Asian and Third World populations. To facilitate this market penetration, political avenues are often pursued with considerable success, disregarding the health implications associated with cigarette tobacco. The use of tobacco in development programs (e.g. the U.S. 'Food for Peace' program) has political and economic implications for donor and recipient countries, and lucrative advantages for the tobacco companies. However, this paper recommends that corporate profits and foreign policy should not be pursued at the expense of tobacco-related diseases and premature deaths among Third World peoples.

Developing Countries↗

PubMed1999

The politics of disclosing female sexual abuse: a case study of Palestinian society.

INTRODUCTION: This paper argues that, by understanding the socio-cultural and political context within which disclosure or non-disclosure of sexual abuse takes place we are better able to develop an analytical framework that might shape culturally sensitive social policy towards sexual abuse and thereby reduce it. METHOD: The data for the study were extracted from records available on 38 cases of sexually abused Palestinian girls, as well as interviews conducted with victims and their parents whenever possible. In-depth interviews were conducted with 19 professionals who dealt with these 38 cases. FINDINGS: Contextual analysis of the data revealed that acknowledgment of sexual abuse took place only in situations where the abuse was extremely traumatic, publically apparent, and the victim absolved of blame. Disclosure resulted in approximately 10% of the cases in the killing of the victim. Responses involving measures such as hymen reconstruction, marriage to the rapist, and abortion were used by family and society to "nullify" sexual abuse. The intricacies bearing on the decision to disclose or not disclose sexual abuse were discussed within a socio-cultural and political frame of reference. A paradigm of analysis is provided to clarify this complex relationship.

Abortion, Induced↗

PubMed1997

Regulating biotechnology: a rational-political model of policy development.

While technology assessment is seen as a mechanism for achieving effective and efficient use of health care resources, it has not as yet made the impact on policy decisions that its potential would suggest. Considerable barriers have been encountered in translating assessment results into policy concerning the adoption and use of technologies, with 'political' factors often being decisive. This paper places technology assessment in the content of the policy process to clarify both (a) how conflicting interests and organizational features can often hinder the selection of optimal policies, and (b) the potential roles technology assessment could nonetheless play. The resulting framework is termed the 'rational-political' model of policy development. The paper uses the example of policy making about the regulation of biotechnology, drawing on information from a survey of decision-makers (n = 561) involved in issues concerning the development, approval, and payment for pharmaceutical products.

Biotechnology↗

PubMed2001

Toward a bio-cultural and political economic integration of alcohol, tobacco and drug studies in the coming century.

The 18th and early 20th centuries witnessed the disintegration of a unified approach to understanding the human condition. Political economy, the broad study of human society, fragmented into an array of university-based disciplines, each reductionistically focused on its narrow arena of specialized research. Medicine, which had been concerned with health in social and historic contexts, narrowed its focus to the microscopic level and to encapsulated understandings of the immediate effects of pathogens and of the structures of disintegrated organ systems. Similarly, anthropology, which continued to wave a banner of holism, retreated for much of the 20th century into fine-grained cultural studies of seemingly isolated human communities on the one hand, and highly specialized biological and biobehavioral analyses of only tangential concern to cultural concerns on the other. Consequently, it has appeared at times as if anthropology would fragment into two or more disciplines and the opportunity for an integrated understanding of the human condition would be lost in the process. As we approach ever closer to the 21st century, however, the felt need for interdisciplinary and intradisciplinary reintegration has grown stronger. This trend is manifest increasingly in the field of alcohol, tobacco, and drug studies, and suggests one of the places anthropology may be going in the future. In this light, this paper examines the use of a critical biocultural model employed in the anthropological assessment of the Hartford Syringe Exchange Program. This model integrates the political economy of risk behavior, the ethnographic examination of insider understandings, meaning systems and behaviors, and the biological analysis of health-related issues. Methodologically, the assessment combined methods and concepts from all of the major subfields of anthropology.

Anthropology, Cultural↗

PubMed1995

Prevalence of eating disorders and minor psychiatric morbidity in central Europe before the political changes in 1989: a cross-cultural study.

The prevalence of culture-bound syndromes such as eating disorders in the countries of Central and Eastern Europe is unclear and comparative epidemiological studies are lacking. Before the political changes in 1989 we therefore investigated eating disorders, eating attitudes and psychological health in two Eastern European countries and in one Western democracy. A total of 1225 female and male medical students in Hungary, the German Democratic Republic (GDR) and Austria were surveyed. The instruments included the Eating Disorder Inventory and the GHQ. The prevalence of eating disorders was calculated on the basis of simulated DSM-III-R diagnosis. In females, bulimia nervosa prevalence rates of 0.6% (95% CI 0.02, 3.46), 1% (0.2, 2.95) and 0% (0, 2.07) were calculated for Austria, Hungary and the GDR, respectively. For subclinical bulimia nervosa, the rate for Hungary (3.8%; 1.95, 6.72) was twice as high as for Austria (1.9%; 0.39, 5.5) and the GDR (1.7%; 0.36, 4.88). Hungarian subjects indicated more psychiatric 'caseness' than their GDR or Austrian counterparts. We conclude that eating disorders represented at least as common a problem in Eastern as Western Europe before the changes in political organization. This may be due to an identification process with Western values. A further increase of eating disorders in these countries induced by the recent changes may be possible.

Adult↗

PubMed2006

The rise and fall of the medical gaze: the political economy of immigrant medical inspection in modern America.

In this paper I examine the mass medical inspections of immigrants to the United States from the 1890s through the 1920s. I show how, framed as it was not only by nativism and eugenics but also by national industrial imperatives and priorities, scientific medicine served dual purposes. On the one hand, the medical exam was a tool for managing cultural and biological threats to the nation. There were regional variations in medical inspections that reflected the politics of race. On the other hand, the medical exam played an important role in the process of building an unskilled, highly mobile labor force. The industrial demands of the nation provided a rationale for drawing and absorbing millions of European immigrants into the labor force. It was thus a distinct product of the political economy of immigration. It was this second function that characterized the exam for the majority of immigrants entering the nation.

Asia↗

PubMed2001

The relationship of political party affiliation to wildlife conservation attitudes.

Species conservation via the Endangered Species Act is highly politicized, yet few data have been gathered to illustrate the relationship of political party affiliation to species conservation perspectives. We conducted a nationwide public opinion survey and found that Democrats value species conservation more highly than do Republicans, and that Democrats are also more strongly supportive of the Endangered Species Act. Republicans place higher value on property rights than do Democrats, but members of both parties value economic growth as highly as wildlife conservation. The results imply that the Democratic propensity to value species conservation reflects a biocentric perspective that does not bode well for practical conservation efforts. Species conservation will depend upon the success of academicians and progressive political leaders in educating students and members of all parties about the fundamental conflict between economic growth and wildlife conservation.

Journal Article↗