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At least 739 records · Page 41Linked to original sources
PubMed1995

Longitudinal study on the changes of maxillary arch dimensions in Japanese children with cleft lip and/or palate: infancy to 4 years of age.

The focus of this study was an analysis of maxillary arch growth changes prior to the time of cheiloplasty up to 4 years of age. Serial dental casts were obtained and measured in 95 children with cleft lip and palate, or both: 7 unilateral cleft lip and alveolus (CLA), 52 unilateral cleft lip and palate (UCLP), 24 bilateral cleft lip and palate (BCLP), and 12 isolated cleft palate (CP). The children were treated at the Kyushu University Dental Hospital. The results are as follows: (1) Prior to cheiloplasty, the maxillary buccal segments in the subjects with cleft lip and palate showed lateral displacement. The premaxilla in BCLP subjects was protruded. (2) Cheiloplasty influenced maxillary anterior arch width, but not posterior width. The operation caused posterior displacement of the premaxilla in BCLP subjects. (3) Palatoplasty affected the growth of the maxillary arch in the transverse and anteroposterior dimensions. (4) A variety of growth patterns observed in the patients (e.g., increasing or decreasing of the maxillary arch dimensions) suggests that maxillary arch dimensions were affected not only by surgery, but also by other individual factors such as genetic facial pattern and severity of the cleft.

Alveolar Process↗
PubMed1988

The step technique for the reconstruction of lower lip defects after cancer resection. A follow-up study of 165 cases.

One hundred and sixty-five patients with localized cancer of the lower lip were excised and reconstructed over a 25-year period using Bengt Johanson's step technique. Eight-eight percent of the tumors were less than 2 cm in size and 65% were of high histopathological differentiation. Fifty-six percent were reconstructed with bilateral step flaps. Nine local recurrences appeared in 5 patients, none of whom died of lip cancer. Eight patients later developed regional metastases and 3 of these patients died of lip cancer. The 5-year survival rate was 98%. The step technique is recommended for reconstruction of lip defects of up to 2/3 of the lower lip and may, in larger resections, be combined with either a fan flap or an Estlander flap. The outstanding functional results are due to the use of adjacent tissue for the reconstruction which preserves the normal arrangement of muscles, vessels and nerves.

Adult↗
PubMed1992

Craniofacial development in children with unilateral clefts of the lip, alveolus, and palate treated according to three different regimes. Assessment of nasolabial appearance.

From extraoral photographs taken from the front and in profile of 61 16-year old children with unilateral cleft lip, alveolus, and palate (UCLAP) who had been treated by three different treatment regimes, the nasolabial appearances were assessed by a panel. The photographs were masked, leaving only the mid face including the nose and lips. The following features were assessed using a five point scale: nasal form, symmetry of the nose, vermilion of the upper lip, shape of the vermilion border, total symmetry of upper lip, and nasal profile including the upper lip. The number and type of secondary operations required were recorded. Intraobserver reliability was good but interobserver agreement was poor, some observers systematically scoring more severely than others. A panel of six was therefore set up to establish an acceptable mean assessment. The treatment regime that included secondary bone grafting, and the one that included primary bone grafting and presurgical orthopaedic-T-traction, scored better on all features assessed compared with the group that underwent primary bone grafting but no T-traction. The latter group required fewer secondary revisionary procedures, however, which could explain these results.

Adolescent↗
PubMed2003

[Mechanisms disordering wound healing on the lip after bilateral crossing of the inferior alveolar nerve and experimental validation of correction methods].

The mechanisms of lip wound healing after bilateral crossing of the inferior alveolar nerve (IAN) were studied on Chinchilla rabbits in 3 experimental series, 6 animals per series. In group 1 bilateral crossing of IAN was carried out, in group 2 bilateral crossing of IAN was paralleled by removal of a mucous flap in the middle of the lower lip, and in group 3 the same wound as in group 2 was created, after which the wounds in this group were daily treated with a special ointment and a single injection of lidocaine (1% solution) under the wound. The nerve crossing led to development of ulcer on the lip with degenerative changes in the vascular walls, destruction of nerve fibers, and fragmentation of some axial cylinders. Crossing of IAN simultaneously with removal of the lower lip flap led to more severe degenerative changes in the tissue. Daily treatment of the lip with the ointment and lidocaine blocking normalized wound healing. A possible mechanism of the changes observed is discussed.

Anesthetics, Local↗
PubMedDate not supplied

Use of nasoalveolar molding appliance to direct growth in newborn patient with complete unilateral cleft lip and palate.

The alignment of the alveolar segments creates the foundation upon which excellent results of lip and primary nasal surgery are dependent in the repair of the cleft lip and palate patient. The purpose of this article is to illustrate the step-by-step fabrication process of the nasoalveolar molding appliance used to direct growth of the alveolar ridge, lips, and nose in the presurgical treatment of cleft lip and palate. As a result of this appliance, the primary surgical repair of the nose and lip heals under minimal tension, thereby reducing scar formation and improving the esthetic result.

Alveolar Process↗
PubMed1992

Effects of lip adhesion and presurgical orthopedics on facial growth: an evaluation of four treatment protocols.

Differences in craniofacial morphology in uni and bilateral cleft lip and palate were studied by roentgenocephalometry: 35 American children, treated with a lip adhesion procedure, and 26 Dutch children treated with a preoperative orthopedic procedure, both followed by a lip and/or palatal repair, were compared. A multivariate statistical approach was used to study the effects of the surgical procedures and of the age of the child when operated upon. The variables affected by the type of operation were: the relative length of the maxilla (PNS-ANS); the SNA angle; and the relative length of the mandible (Go-Po). The length of the maxilla was on average longer for those treated with preoperative orthopedics and the maxilla was largest for children whose hard palate had yet to be closed. This was also the case for the SNA angle except for children treated with the combined lip-soft palate closure procedure. The mandible followed pattern displayed by the maxillary length; it was larger for those treated with preoperative orthopedics. Significant effects of the timing of the surgery on the variables studied were also found. Postponement of the definitive lip closure resulted in a reduction of the maxillary length, whereas delay of soft palatal closure resulted in an increase of the maxillary length.

Activator Appliances↗
PubMed2001

Reconstruction of the lower lip.

INTRODUCTION: There are studies reporting the functional advantages of radiotherapy against surgical treatment. PURPOSE: Because of this we decided to substantiate the surgical treatment as a method of choice in the reconstruction of defects of lower lip after cancer resection. MATERIAL AND METHODS: The author has developed a modification of the method of Bernard for reconstruction of defects of the lower lip after cancer resection. RESULTS: A horizontal incision is made from the angle of the mouth to the cheek, and at the end of the incision a triangle of Burov is cut. After the resection of the tumour, from the lower edge of the defect (the transitional fold), a second incision is done with orientation to the submandibular area at the end of which a second triangle of Burov is cut. The incision takes into consideration the direction of skin folds for achieving better esthetic effect. This refined method was applied in 14 patients with lower lip carcinoma, 7 of them with unilateral flaps and 7- with bilateral flaps from 1994 to 1999. CONCLUSIONS: The functional and esthetic results of the modified method for lower lip reconstruction are better because they lead to better mobility, symmetry of the reconstructed lower lip and optimal wideness of the mouth and the sensitivity is preserved. A mathematical method for planning of the tissues, needed for the replacement of the defect after the excision of the tumour in healthy tissues are under development.

Humans↗
PubMed2006

Congenital lower lip pits (Van der Woude syndrome): report of a case.

Van der Woude syndrome (VWS) is a rare autosomal dominant disorder that is characterized by a cleft lip and palate with congenital lip pits. This is a report of a case of VWS with sinuses in the lower lip, a cleft in the upper lip, and a supernumerary tooth in the maxilla. The main characteristics of this disorder are discussed. Dental treatment of the patient was performed, but the surgical removal of the sinus was rejected by the parents. This case report brings this condition to the attention of dentists and surgeons and emphasizes lip pits may not always be identical in appearance.

Child↗
PubMed1986

[Surgical treatment of congenital bilateral cleft lip].

Operations were performed on 23 patients with bilateral cleft lips by the method of Mirault--Limberg--Kardozo. Five patients had bilateral symmetrical total cleft lips, eight patients had bilateral nonsymmetrical total cleft lips, ten patients had bilateral incomplete cleft lips. One-stage operations were used in 17 patients, two-stage operations--in six patients. The method consists in the angle-shaped refreshing and uniting the margins of the cleft which provides the possibility to restore the correct form of the Cupid arch. The method is most expedient in children with bilateral non-symmetrical cleft lips with the well-developed median portion. Long-term results were studied in 19 children. Good and excellent results were noted in 12 patients, satisfactory--in 7 patients.

Child↗
PubMed1987

[Dominantly inherited lower lip fistulas and facial clefts (Van der Woude syndrome). A study of 52 cases].

Congenital lip pits may occur alone or in combination with oral clefts. They characteristically present as symmetric pits close to the vermilion border of the lower lip, about 0.5 cm off the midline, and are usually connected with heterotopic salivary glands; occasionally, salivation may occur. Congenital lip pits are associated with clefts of the upper lip and/or the palate in about half of the cases. Hypodontia may also be observed. Lip pits with or without clefts are found in a few dominantly inherited syndromes, in most cases involving the autosomal dominant Van der Woude syndrome. 52 carriers of the Van der Woude gene are described. In 8 cases the syndrome occurred as a fresh mutation and the other 44 cases occurred in 5 families. Penetrance was complete and expression very variable. Sex distribution was 1:1. For genetic counselling purposes it can be concluded that all carriers of the Van der Woude gene can be identified. Every symptom (pits, micro-pits, cleft, submucous clefts, uvula bifida) may represent the only manifestation of the gene. The recurrence risks for offspring of gene carriers is 50%, but the risk of severe forms of cleft is much lower.

Adult↗
PubMed1985

Repair of unilateral cleft lip: the rotation-advancement operation.

The most obvious deformity in a unilateral cleft of the lip is asymmetry of the lip and nose. Operation must repair the cleft, lengthen the lip, restore muscle continuity, and create an adequate labial sulcus. Simultaneous correction of the nasal deformity should be carried out to the greatest extent possible at the same time. The rotation-advancement repair has advantages over other repairs in scar placement, correction of the nasal deformity, and conservation of lip and nose tissue. If revision of the lip or nose is required, it can be accomplished more easily following the rotation-advancement repair than other techniques.

Child↗
PubMed1980

Sliding block resection and reconstruction in cases of carcinoma of the lower lip.

Surgical eradication of carcinoma of the lower lip is generally a curative maneuver. Concomitant reconstruction at this site is almost always necessary, however, and difficulties in these efforts often arise. Postoperative esthetic problems usually result when more than 30% of the lip has been removed; the most common problems are vertical scar retraction along the mucosal surface, unacceptable distortion of the commissure or overall asymmetry of the oral aperture, or both, and significantly disturbed lip motor function. During the past decade, the surgical procedure described has allowed excision of 40% of the lip and provided vertical support of the reconstructed lip and an ultimate facial appearance superior to that of other techniques.

Carcinoma, Squamous Cell↗
PubMedDate not supplied

Facial growth and development in unilateral cleft lip and palate from the time of palatoplasty to the onset of puberty: a longitudinal study.

X-ray cephalometry was used for the assessment of facial growth and development from the time of palate surgery to the onset of puberty (from 5 to 11 years) in 24 boys with unilateral cleft lip and palate treated with primary periosteoplasty (at 8 months) and palatal pushback supplemented by pharyngeal flap surgery (at 5 years). The lowest growth showed the depth of the maxilla and the height of the upper lip. An increasing protrusion of the mandible and in particular the increasing retrusion of the maxilla resulted in a flattening of the face and in an impairment of sagittal jaw relations. However, it was possible to attain an improvement of overjet produced by a substantial increase of the proclination of upper incisors and of the alveolar process. There was a deterioration of the prominence of the upper lip. Anterior growth rotation was absent during the development of the face, though a rotation in both directions was quite common in individual cases. The steepness of the mandibular body, vertical jaw relations, and facial vertical proportions remained unchanged. As compared to the pubertal period, the growth and development differed only by a more marked proclination of the dentoalveolar component of the maxilla and by an improvement of overjet. Facial convexity and sagittal jaw relations deteriorated in more than 90% of the patients, the overjet only in 20%, yet the prominence of the lip in 70%. Facial convexity and sagittal jaw relations were not correlated with mandibular rotation but they affected the overjet and the prominence of the upper lip.(ABSTRACT TRUNCATED AT 250 WORDS)

Cephalometry↗
PubMed1994

[Artery supply of the lip and palate in normal and cleft patients].

50 normal and 10 cleft lip and palate head and neck specimens were studied by dissection and arteriography. The results are as follows: 1. In unilateral complete cleft lip, the superior labial artery runs along the labial margin and cleft edge, ending in base of nasal wing on the lateral side. In the medial side, upper labial artery ends in the base of the columella. 2. In the bilateral complete cleft lip, artery supply of superior lip is similar to the lateral side of unilateral complete cleft lip. The artery supplying the philtrum and premaxilla comes from the posterior septal artery, anterior ethmoid artery, nasal alar artery and/or lateral nasal artery. 3. Normal palate is supplied by six pairs of arteries. They are greater and lesser palatine artery, lesser palatine artery, nasopalatine artery, ascending palatine artery, ascending pharyngeal and palatine, artery tonsillar artery. In the cleft palate, the anterior branch of the ascending palatine artery becomes smaller and the posterior branch has shifted forward and runs forward along the cleft edge. The palatine branch of the ascending pharyngeal does not run along the palato--pharyngeal muscle, but descends from the base of skull along the levator palate muscle to the soft palate.

Arteries↗
PubMed1995

[Repair of tissue loss of the lips].

The main aim in lip reconstruction is to recreate a sphincter activity and obtain lip balance. Careful evaluation of the defect is essential and will lead the surgeon to choose the best and most suitable procedure. Wedge excision with direct suture, opposite full-thickness lip switch flap and Karapandzic procedure are presented in this paper. The axiom is "Use lip to repair lip".

Facial Injuries↗
PubMed1977

Some observations concerning the demographic and geographic incidence of carcinoma of the lip and buccal cavity.

The geographic and demographic data obtained during the Third National Cancer Survey have provided a perspective on etiologic factors and incidence trends for cancers of low frequency. The incidence of cancer of the lip, oral cavity and skin from this survey was compared to similar studies in 1947 and intra-regional patterns in one area of the Third National Cancer Survey (Dallas-Fort Worth Metropolitan SMSA) were evaluated. The average age-adjusted annual incidence of cancer of the lip in white men in this latter area was 11.5 per 100,000 (based on 1950 population standard), 2-fold greater than that geographic area with the second highest incidence and approximately 3-fold greater than in all the other areas. The incidence in white women was only 8% that seen in white men. Intra-regional differences of similar populations were seen with the incidence in Fort Worth men being 50% greater than in a similar population in Dallas. Incidence trends over the past 2 decades reveal a significant decline in the incidence of oral cavity cancer and a slight decrease in lip cancer. Comparisons of the incidence of lip cancer did not correlate with the incidence of skin cancer nor with geographic latitude in the other survey areas. The studies fail to support the classical implication of actinic radiation as the primary etiologic factor in lip cancer incidence.

Age Factors↗
PubMed1992

Lip cancer. Incidence trends in Connecticut, 1935-1985.

Suspicions have recently arisen that cancer of the lip may exert an undue influence on overall oral cancer statistics and, therefore, possibly distort the true image of intraoral cancer. The authors investigated this question through epidemiologic analysis. A total of 2291 cases of lip cancer accessioned by the Connecticut Tumor Registry (CTR) from 1935 to 1985 (23.6% of all oral cancer) were analyzed. Occurrence trends for males and females had different patterns: for men, the age-adjusted incidence rates showed a fivefold decrease during the 51-year study; for women, the rates were relatively low and constant during the same period. Analysis for age-specific rates revealed that the older the age group, the higher the incidence rates for both sexes. Squamous cell carcinoma accounted for at least 87.4% of all lip cancers (96.2% if nonspecified epithelial neoplasms are assumed to be squamous cell carcinoma). The vermilion border of lower lip was the most common site. Moderately differentiated tumors were most common (48.5%), closely followed by well-differentiated tumors (44.2%). Analysis by county showed that the crude incidence rates for males in New London and Windham counties exceeded the average Connecticut statewide rates. The authors concluded that the epidemiology of Connecticut lip cancer differs significantly from that of intraoral squamous cell carcinoma in the same population studied within the same period of time. Epidemiologic studies involving "oral cancer" should direct attention to anatomic subsite to consider differences in disease trends according to specific location.

Adenocarcinoma↗
PubMed1992

Restricted junctional usage of T cell receptor V beta 2 and V beta 13 genes, which are overrepresented on infiltrating T cells in the lips of patients with Sjögren's syndrome.

OBJECTIVE: To analyze the clonality of T cell receptor (TCR) V beta 2- and V beta 13-positive T cells, which are predominantly expressed in the lips of patients with Sjögren's syndrome (SS). METHODS: The junctional sequences of complementary DNA clones encoding TCR V beta 2 and V beta 13 genes were determined by the polymerase chain reaction. Forty-one V beta 2 and 45 V beta 13 clones established from the lips of 3 SS patients were sequenced. RESULTS: The V beta 2/J beta 2.3 pair was enriched in 2 of the 3 patients (44% and 46% of the clones, respectively), and the V beta 13/J beta 2.1 sequence was dominant in 2 of the 3 (23% and 45%). These pairs were not used preferentially in peripheral blood lymphocytes from the same patients. CONCLUSION: Infiltrating V beta 2- and V beta 13-positive T cells from the lips of all 3 patients with SS were polyclonal, but the junctional usage of cells from 2 lip samples was restricted, compared with cells from peripheral blood. This suggests that not all expanded cells from the lips of SS patients are stimulated by superantigens.

Base Sequence↗