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[Combination therapy of acute intestinal obstruction].

The article discusses the results of complex surgical treatment of 108 patients with acute intestinal obstruction which was caused by benign lesions in 64 and by malignant tumors of the rectum in 44 patients. Twenty-three persons (21.2%) died after palliative and radical operations. The main causes of death were intoxication (52.2% of fatal cases) and peritonitis (26.1%). Hemosorption is the most effective measure for the prevention and treatment of the endogenous intoxication syndrome in the postoperative period. A brief therapeutic effect or inefficacy of hemosorption is evidence of persistence of the pathological process in the abdominal cavity.

Acute Disease↗

[Bioelectrical activity of the gastrointestinal tract in acute intestinal obstruction].

During the period of 2001-2002 in the surgical department of the Republican clinical hospital there were 72 patients with acute small bowel obstruction. In addition to generally accepted methods of diagnosing the acute intestinal obstruction including general rentgenography of organs of the abdominal cavity, radiopaque methods, ultrasound scanning of organs of the abdominal cavity, a measuring-diagnostic system (polygastroenterograph "PGEG-2001") was used which registered and processed fluctuation of biopotentials of different parts of the gastrointestinal tract and measured instantaneous values of the intracavital gastric pressure. So, a short period of time was needed to reliably determine the kind and level of obstruction.

Acute Disease↗

The value of Gastrografin in the differential diagnosis of paralytic ileus versus mechanical intestinal obstruction: a critical review and report of two cases.

Two cases in which serious intra-abdominal complications were masked by results of the contrast examination using Gastrografin were encountered. This caused the authors to review critically the use of Gastrografin in the differential diagnosis of paralytic ileus versus mechanical intestinal obstruction. In a series of 41 cases in which the diagnostic problem was not solved initially by means of physical examination and plain abdominal roentgenograms, the Gastrografin examination proved reliable in 28 (68 per cent). The reliability of the examination was defined as the relative number of cases in which a correct decision could be made for or against surgical operation. It is concluded that Gastrografin is a valuable diagnostic aid in controversial cases of ileus. A "negative" result of the examination, however, would never be allowed to damp the surgeon's awareness of possible serious intra-abdominal conditions, which the contrast examination has failed to disclose and which require immediate surgical intervention.

Adult↗

Major causes of intestinal obstruction in Libya.

The object of this study is to focus attention on the causes of intestinal obstruction in Libya. In this study, spread over 30 months and involving 114 patients, the most common cause was the entrapment of bowel in an external hernia. Postoperative adhesions accounted for obstruction in a third of our patients, and 59 per cent of them followed appendicectomy. Biliary lithiasis is the most common surgical disease in Libya, yet there was only one instance of gallstone ileus in this series. Sigmoid volvulus and intestinal lymphoma were also rare, and tubercular stricture and Crohn's disease were remarkable by their absence. There were no cases of idiopathic intussusception during or immediately following Ramadan.

Adolescent↗

Intestinal obstruction caused by bezoar: a rare complication after bone marrow transplantation.

Gastrointestinal complications are described frequently after preparation of patients for bone marrow transplantation (BMT). Two patients who underwent BMT developed complications due to gastrointestinal bezoars. One patient developed intestinal obstruction, which necessitated emergency surgery, and the other patient had a gastric bezoar, which caused vomiting. The diagnosis and treatment of this rare complication after BMT are described.

Adult↗

Endometriosis--the problems of intestinal obstruction.

Endometriosis is a relatively common condition in women of child-bearing age, and coincidental intestinal serosal involvement is frequently recognised. However, intestinal obstruction, although reported, is rare. We report what we believe is the first case with synchronous ileo-caecal and rectosigmoid obstructing endometriomas. Endometriosis as a cause of bowel obstruction is discussed and in particular the differential diagnosis from Crohn's disease and malignancy.

Adult↗

Modern management of cancer-related intestinal obstruction.

Malignant-associated bowel obstruction remains a common and perplexing problem for patients with advanced gynecologic and gastrointestinal malignancies. The ability to locate and define its cause preoperatively has improved with the advent of computed tomography. Initial clinical experience with half-Fourier acquisition single-shot turbo spin-echo magnetic resonance imaging (HASTE MRI) and virtual colonoscopy is exciting. The surgical approach for primary obstructing colon cancer has become more aggressive, with experienced surgical groups doing one-stage procedures. Yet to be defined are guidelines for surgical management of obstructions occurring in the face of recurrent disease. Stent placement for upper and lower bowel obstructions is an option in nonoperable patients. Pharmacologic symptom management for intestinal obstructions consists of an opioid, an anticholinergic, and an antiemetic. Octreotide, either alone or added to the original regimen, will palliate symptoms that are resistant to the three-drug combination.

Female↗

Modern management of cancer-related intestinal obstruction.

Malignant associated bowel obstruction remains a common and perplexing problem for patients with advanced gynecologic and gastrointestinal malignancies. The ability to locate and define its cause preoperatively has improved with the advent of computed tomography. Initial clinical experience with half-Fourier acquisition single-shot turbo spin-echo magnetic resonance imaging (HASTE MRI) and virtual colonoscopy is exciting. The surgical approach for primary obstructing colon cancer has become more aggressive, with experienced surgical groups doing one-stage procedures. Yet to be defined are guidelines for surgical management of obstructions occurring in the face of recurrent disease. Stent placement for upper and lower bowel obstructions is an option in nonoperable patients. Pharmacologic symptom management for intestinal obstructions consists of an opioid, an anticholinergic, and an anti-emetic. Octreotide, either alone or added to the original regimen, will palliate symptoms that are resistant to the three-drug combination.

Clinical Protocols↗

[Intestinal obstruction secondary to endometriosis of the colon].

Endometriosis is defined as the presence of endometrial tissue outside the uterine cavity. Although in most cases it is a benign disorder, it may be aggressive producing local invasion and even metastasis. Endometrial implantation has been reported in many organs including the small and large intestine leading to acute or chronic symptomatology. The clinical picture of intestinal obstruction is due to stenosis produced by the adherences or fibrosis caused by endometrial sloughing. We present a case of intestinal endometriosis with clinical manifestation of obstruction of the colon. This disorder should be included in the differential diagnosis of fertile females presenting intestinal obstruction with no other predisposing factors.

Colonic Diseases↗

[Laparoscopic operations in acute adhesive intestinal obstruction in children].

Results of treatment of 148 children suspected for acute adhesive intestinal obstruction (AAIO) after laparoscopy are analyzed. Age of the patients ranged from 3 weeks to 14 years. There were 90 (61.4%) boys and 58 (38.6%) girls. Diagnosis of AAIO was confirmed in 129 patients (other diseases were revealed in 19 children). Laparoscopic adhesiotomy was impossible in 13 cases because of contraindications (necrosis of strangulated intestine, abscess-forming infiltration, general adhesive process). Laparoscopy was performed by specially developed technique decreasing the risk of examination in the conditions of adhesive process. The contraindications to laparoscopic adhesiotomy were developed. Laparoscopy permitted to remove the obstruction in 79.8% patients with AAIO. There was one intraoperative complication--colon injury in the area of earlier spontaneously closed fistula (laparotomy and suturing of colon's defect were performed). Postoperative period after laparoscopic operations was easier than after open operations: physical activity of the patients recovered quickly, number of postoperative complications decreased more than 3 times, hospital stay reduced more than 2 times. There were no lethal outcomes.

Acute Disease↗

Inflammatory fibrous polyp (pseudotumor) of ileum, a rare cause of intestinal obstruction.

Inflammatory fibrous polyp of the ileum is a rare condition. This report adds one patient to the 11 previously reported. These lesions usually involve intermittent, colicky abdominal pain, often of several weeks duration and occasionally as a cause of acute intestinal obstruction. X-rays usually show small bowel obstruction or intussusception, but may be completely normal. The pathological diagnosis is seldom made before microscopic examination of resected specimens. They are clinically interpreted to be neoplasm and treated by segmental resection. No recurrences have been reported after treatment. Etiology is unknown.

Female↗

[Non-Hodgkin's lymphoma as a cause of intestinal obstruction in school-age children].

Between 1972 and 1988, twenty-four children with abdominal non-Hodgkin's lymphoma (NHL) were treated. Five children between 6 and 12 years old had intestinal obstruction due to mesenteric-intestinal mass of the NHL class. We report clinical and morphological features, emphasizing the importance of radical surgery from the therapeutic and prognostic points of view these resectable abdominal forms.

Child↗

[An experimental assessment of methods for applying intestinal sutures in intestinal obstruction].

The results of various methods used in applying intestinal sutures in obturation were studied. Three series of experiments were conducted on 30 dogs--resection of the intestine after obstruction with the formation of anastomoses by means of double-row suture (Albert--Shmiden--Lambert) in the first series (10 dogs), by a single-row suture after V. M. Mateshchuk [correction of Mateshuku] in the second series, and bu a single-row stretching suture suggested by the author in the third series. The postoperative complications and the parameters of physical airtightness of the intestinal anastomosis were studied in dynamics in the experimental animals. The results of the study: incompetence of the anastomosis sutures in the first series 6, in the second 4, and in the third series one. Adhesions occurred in all animals of the first and second series and in 2 of the third series. Six dogs of the first series died, 4 of the second, and one of the third. Study of the dynamics of the results showed a direct connection of the complications with the parameters of the physical airtightness of the anastomosis, and the last-named with the method of the intestinal suture. Relatively better results were noted in formation of the anastomosis by means of our suggested stretshing continuous suture passed through the serous, muscular, and submucous coats of the intestine.

Anastomosis, Surgical↗

Survival following intestinal obstruction in ovarian cancer.

A retrospective survey of 38 ovarian cancer patients who developed radiologically confirmed intestinal obstruction was performed. Twenty-six patients underwent surgery. In the surgical treatment group, obstruction was not due to recurrent disease in six cases. The median survival for the group as a whole was 56 days. Patients in the operative group survived significantly longer than those in the non-operative group. There was an operative mortality of 15% and major postoperative morbidity was seen in 42%. Neither the site of the obstruction nor the type of operation influenced survival. No postoperative chemotherapy responses were seen in previously treated patients.

Adult↗