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[Geography of diabetes (1960-1970-1980)].

Crude death rates show great discrepancies in diabetic mortality between industrialized and developing countries, the latter being less affected by diabetes mellitus. Nevertheless, when age is controlled, the gap becomes much narrower. For instance, the crude death rates in males by diabetes mellitus rise to 20.6 per 100,000 population in Belgium, and only 5.8 in Costa Rica (difference: 14.8). But after controlling age, the gap becomes only 2.8 (13.4 in Belgium and 10.6 in Costa Rica). As a matter of fact, the main difference between industrialized countries and those in the Third World is that diabetic mortality occurs at older ages in the former and at younger ages in the latter. Generally speaking, diabetic mortality is increasing in the developing countries, due most probably to improved data collection. In France, diabetic mortality was growing in the "départements" of the Nord Est and the Languedoc, and many rural areas were also experiencing a rising mortality rate. On the other hand, the rate was decreasing in Brittany and the Paris area.

Age Factors↗

[Genetic geography of inherited dimorphism of ear wax by its consistency].

Data on cerumen types were collected in three population groups of Pamir mountain region. The observed frequencies of dominant w and recessive d alleles which determine wet and dry types of ear wax are equal, accordingly: in Khuf population (Western Pamir) to 0.6603 and 0.3397; in Pastkhuff population (Western Pamir) to 0.6078 and 0.3922; in Kirghizes of Central Pamir to 0.3606 and 0.6394. We present data on cerumen types in 23 populations of the USSR also. The world information on distribution cerumen types was summed up (over 80 populations). No connection of gene frequencies of cerumen with natural abiotic factors of environment was revealed. Strong correlation of the genes described with mongoloid peculiarities was established: epicanthus r = 0.718, the haplotype Gmz, a, b, 0, 3, 5, s, t (Gm(1, 11, 13, 15, 16) r = 0.522.

Cerumen↗

[Lipid peroxidation as an indicator of the adaptive capacity of patients with chronic bronchitis during sanatorium and health resort treatment with a change in climate and geography].

Lipid peroxidation (LPO) in the blood plasma and erythrocytes was studied in 99 inhabitants of the southern part of West Siberia suffering from chronic bronchitis, of them 64 with obstructive bronchitis. They were sent for treatment to the contrast climatic zone (Yalta, the Crimea), and LPO was examined before the trip and after return in the course of a month (three times). LPO activity at a later stage as compared to the initial one was raised in the patients with signs of disadaptation (54 patients). The time course of LPO up to the initial level was over up to the 12th day after return in the patients with moderate symptoms of disadaptation in the warm season and up to the 30th day in the cold period. LPO activity in the patients with pronounced symptoms of disadaptation was more noticeable, the time course of the indicators up to the initial level was more delayed, particularly in erythrocytes and in the cold season. Thus LPO activity in chronic bronchitis in terms of its expression and period depends on patients' adaptogenicity to contrast change of climatic geographic zones after therapy in a sanatorium.

Acclimatization↗

The geography of chronic digestive disease in southern Africa.

Lifestyle and dietary patterns are in the process of rapid transformation in Soweto. Comparisons with whites indicate differences in bowel behaviour, lactase deficiency and breath methanes. The association between smoking pipe tobacco and cancer of the oesophagus is confirmed, but home-brew consumption has been found to be the major risk factor in this cancer. A recent swing to Western-type alcohol has led to the emergence of alcohol-induced pancreatitis in blacks. Urbanisation and westernisation have also affected the influence of the traditional healer and the incidence of duodenal ulcer disease. The fundamental environmental influence which determines non-infective large-bowel disease is diet. A dietary survey of Sowetans indicates that their present diet is low in fat and fibre. Despite the latter, appendicitis is still relatively uncommon. Other significant differences are observed in colorectal cancer and diverticular disease.

Black or African American↗