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Causes of low vision and blindness in adult Latinos: the Los Angeles Latino Eye Study.

OBJECTIVE: To describe the causes of low vision and blindness in a population-based sample of adult Latinos. DESIGN: Population-based cross-sectional study. PARTICIPANTS: Six thousand three hundred fifty-seven Latinos 40 years and older from 6 census tracts in Los Angeles, California. METHODS: Participants underwent a detailed ophthalmologic examination including measurement of best-corrected distance visual acuity using a standard Early Treatment for Diabetic Retinopathy Study protocol, a complete anterior and posterior segment evaluation by an ophthalmologist, Humphrey Visual field testing, and optic disc and fundus photography. Consensus diagnosis of independent investigators reviewing all patient data was used to determine the major causes of low vision and blindness in adult Latinos. MAIN OUTCOME MEASURES: Primary causes of vision loss in persons with low vision and blindness. RESULTS: The leading causes of low vision were cataract, diabetic retinopathy, and age-related macular degeneration, together accounting for approximately 82% of all persons with low vision. The primary causes of blindness were age-related macular degeneration, diabetic retinopathy, and myopic degeneration, accounting for 63% of the cases of blindness. CONCLUSIONS: Many of the leading causes of low vision and blindness in adult Latinos are potentially preventable and treatable diseases. Given the projected aging and growth in the Latino population, consideration needs to be given to the development of targeted early detection and treatment programs.

Adult↗

Hepatitis C virus infection and alanine transaminase levels in the general population: a survey in a southern Italian town.

BACKGROUND/AIM: The aim of the study was to estimate the prevalence, risk factors and genotype distribution of hepatitis C virus (HCV) in the general population older than 5 years of age in a southern Italian town. The positive predictive value of alanine transaminase (ALT) screening in identifying HCV positive subjects was also assessed. METHODS: Cluster random sampling from the census of the general population was used. ELISA and RIBA tests assessed the presence of anti-HCV; nested reverse transcription polymerase chain reaction (RT-PCR) was used to identify HCV-RNA; genotyping was performed by INNO-LIPA III. The association linking anti-HCV seropositivity with potential risk factors was assessed by multiple logistic regression analysis. RESULTS: Among the 488 subjects enrolled, 79 (16.2%) were anti-HCV positive. The prevalence increased from 1.2% in subjects 6-29 years of age to 42.1% in those > or = 60 years. Forty percent of these positive subjects also had abnormal ALT level and 54.4% were HCV RNA positive by PCR. The positive predictive value of the ALT test in identifying anti-HCV positive subjects was 65%; however, it was 46.7% in subjects younger than 60 years of age and 90.5% in those 60 or older. Genotype 1b was detected in 74% of subjects, type 2c in 23.3%, and type 1a in 2.3%. The only two variables significantly associated with HCV seropositivity in multivariate analysis were age older than 45 years (O.R. 8.5; CI 95%=3.0-24.1) and past use of glass syringes (O.R. 3.4; CI 95%=1.5-7.6). CONCLUSIONS: These findings confirm that HCV infection is endemic in southern Italy, particularly among the elderly. Percutaneous exposure, such as injections with nondisposable, multiple-use, glass syringes used in the past for medical purposes may have played a major role in the spread of HCV infection. ALT screening is not useful in detecting HCV positive subjects in the general population, particularly among subjects who could benefit from antiviral therapy.

Adolescent↗

[Trends in traffic accident mortality in Spain, 1962-1994].

OBJECTIVE: To assess the evolution of the traffic accident mortality rate in Spain from 1962 to 1994, and the role played by its four theoretical components: motorization index (vehicles/population), accidentability index (accidents/vehicles), harmfulness index (victims/accidents) and fatality index (deaths/victims). METHODS: Data from the National Population Census and the Bulletin of the Dirección General de Tráfico were collected to estimate the above mentioned indicators for all accidents and accidents in road and urban zones. Simple and multiple partial correlation coefficients among variables were calculated. Poisson regression models were also obtained. RESULTS: An increasing trend during the whole period was observed for the national traffic accident mortality rate, especially from 1982 to 1989 in the younger age groups, followed by a decrease since 1990. The aforementioned four components were significatively associated with the mortality rate. The strength of this association was especially high for the motorization index and for the harmfulness index when all accidents and road accidents were considered. For urban accidents, the fatality index rate is the component most strongly associated with mortality rate. The role played by the accidentability index in the magnitude of the mortality rate seems less important. CONCLUSIONS: The growing exposure rate to traffic accidents observed in Spain (measured by the motorization index) is not directly influenced by public heath strategies. Therefore, it seems advisable to emphasize the development of measures focused to control the other three components of traffic accident mortality rate, especially those related with harmfulness and fatality.

Accidents, Traffic↗

School-based health centers: accessibility and accountability.

PURPOSE: To examine the current experience of school-based health centers (SBHCs) in meeting the needs of children and adolescents, changes over time in services provided and program sponsorship, and program adaptations to the changing medical marketplace. METHODS: Information for the 1998-1999 Census of School-Based Health Centers was collected through a questionnaire mailed to health centers in December 1998. A total of 806 SBHCs operating in schools or on school property responded, representing a 70% response rate. Descriptive statistics and cross-tab analyses were conducted. RESULTS: The number of SBHCs grew from 120 in 1988 to nearly 1200 in 1998, serving an estimated 1.1 million students. No longer primarily in urban high schools, health centers now operate in diverse areas in 45 states, serving students from kindergarten through high school. Sponsorship has shifted from community-based clinics to hospitals, local health departments, and community health centers, which represent 73% of all sponsors. Most use computer-based patient-tracking systems (88%), and 73% bill Medicaid and other third-party insurers for student-patient encounters. CONCLUSIONS: SBHCs have demonstrated leadership by implementing medical standards of care and providing accountable sources of health care. Although the SBHC model is responsive to local community needs, centers provide care for only 2% of children enrolled in U.S. schools. A lack of stable financing streams continues to challenge sustainability. As communities seek to meet the needs of this population, they are learning important lessons about providing acceptable, accessible, and comprehensive services and about implementing quality assurance mechanisms.

Adolescent↗

Ecological analysis of teen birth rates: association with community income and income inequality.

OBJECTIVES: To examine whether per capita income and income inequality are independently associated with teen birth rate in populous U.S. counties. METHODS: This study used 1990 U.S. Census data and National Center for Health Statistics birth data. Income inequality was measured with the 90:10 ratio, a ratio of percent of cumulative income held by the richest and poorest population deciles. Linear regression and analysis of variance were used to assess associations between county-level average income, income inequality, and teen birth rates among counties with population greater than 100,000. RESULTS: Among teens aged 15-17, income inequality and per capita income were independently associated with birth rate; the mean birth rate was 54 per 1,000 in counties with low income and high income inequality, and 19 per 1,000 in counties with high income and low inequality. Among older teens (aged 18-19) only per capita income was significantly associated with birth rate. CONCLUSIONS: Although teen childbearing is the result of individual behaviors, these findings suggest that community-level factors such as income and income inequality may contribute significantly to differences in teen birth rates.

Adolescent↗

Is there endoscopic capacity to provide colorectal cancer screening to the unscreened population in the United States?

BACKGROUND & AIMS: Screening rates for colorectal cancer remain low compared with screening rates for other cancers. The size of the unscreened population and the capacity to provide widespread screening are unknown. We estimated the number of average-risk persons aged 50 years or older not screened for colorectal cancer, the number of procedures required for this population, and the endoscopic capacity to satisfy this unmet need. METHODS: Using data from the US Census Bureau and the Centers for Disease Control and Prevention's National Health Interview Survey, we designed a forecasting model to estimate the number of persons in the United States currently not screened for colorectal cancer and the number of examinations needed to screen these persons. Test need was compared with available capacity, based on results from the national Survey of Endoscopic Capacity, assuming different proportions of available capacity were used for colorectal cancer screening. RESULTS: Approximately 41.8 million average-risk people aged 50 years or older have not been screened for colorectal cancer according to national guidelines. Sufficient capacity exists to screen the unscreened population within 1 year using fecal occult blood testing followed by diagnostic colonoscopy for positive tests. Depending on the proportion of available capacity used for colorectal cancer screening, it could take up to 10 years to screen the unscreened population using flexible sigmoidoscopy or colonoscopy. CONCLUSIONS: The capacity exists for widespread screening with fecal occult blood testing. The capacity for screening with flexible sigmoidoscopy or colonoscopy depends on the proportion of available capacity used for colorectal cancer screening.

Aged↗

The growth in noncitizen SSI caseloads 1979-1996: aging versus new immigrant effects.

OBJECTIVES: The goal of this research is to assess the degree to which the recent growth in the rate of Supplemental Security Income (SSI) usage is concentrated among recently arrived elderly immigrants or among earlier arriving immigrants who have "aged in place" and thus become eligible for benefits. METHODS: We use 1980 and 1990 Census data and 1997 Current Population Survey (CPS) data to examine whether the growth in the elderly noncitizen caseload during the 1980s and 1990s may be attributed to increases in rates of receipt among newly arrived elderly immigrants, to increases in rates of receipt among "settled" immigrants who have aged into categories that allow them to obtain SSI benefits, or to increases in the number of persons in each of these groups. RESULTS: We find that the major contribution to the growth in the noncitizen elderly SSI caseload has been the significant increase in the rate of receipt among those who have lived in the United States for more than 10 years (a smaller increase occurred among recent arrivals). This factor accounts for about half of the total growth in the caseload and cannot be explained by increases in poverty among noncitizens. DISCUSSION: The idea that the availability of SSI for elderly immigrants has acted as a magnet for poor elderly immigrants, thereby accounting for the growth in the elderly immigrant SSI caseloads during the 1980s and 1990s, does not receive much support in the findings of this research.

Aged↗

English language skills, ethnic concentration, and household composition: older Mexican immigrants.

OBJECTIVES: The authors examine the living arrangements of older Mexican immigrants to demonstrate how the formation of complex households is related to English language proficiency. Specifically, they examine whether the ability to use the English language is a determinant of an older Mexican immigrant persons' capacity to maintain residential independence. They also examine how living in communities with a relatively high proportion of Hispanic persons impacts household structure. METHODS: Data from the 1990 U.S. Census of Population are used to evaluate multilevel multinomial logistic regression models of living arrangements among older Mexican immigrants. RESULTS: The authors found that strong English language skills increase the likelihood of living independently and increase the likelihood of being the head of a household. They also found that living in an area with a relatively high proportion of Hispanic persons increases the likelihood that older Mexican immigrants will live independently as compared with living with others without headship. Finally, interaction models were examined, demonstrating that living in a community with a relatively high proportion of Hispanics reduces the strength of the relationship between English language proficiency and living arrangement outcomes for older Mexican immigrants. DISCUSSION: The authors discuss the implications of their findings and point out possible avenues for further research.

Activities of Daily Living↗

Cohabitation among older adults: a national portrait.

OBJECTIVE: Older adults are increasingly likely to experience cohabitation, or living together unmarried in an intimate, heterosexual union. In order to begin building a conceptual framework, we provide a descriptive portrait of older adult cohabitors, emphasizing how they compare to older remarrieds and unpartnereds. METHODS: We used data from both Census 2000 and the 1998 Health and Retirement Study ( HRS; Health and Retirement Study, 1998) to estimate the size and composition of the cohabiting population aged 51 and older. Also, using HRS data, we estimated multinomial logistic regression models to identify the correlates associated with cohabitation and remarriage (vs being unpartnered) among women and men who were previously married. RESULT: More than 1 million older adults, composing 4% of the unmarried population, currently cohabit. About 90% of these individuals were previously married. We identify significant differences among cohabitors, remarrieds, and unpartnereds across several dimensions, including sociodemographic characteristics, economic resources, physical health, and social relationships. Cohabitors appear to be more disadvantaged than remarrieds, and this is especially evident for women. DISCUSSION: Older cohabitors differ from individuals of other marital statuses, and therefore future work on marital status should explicitly incorporate cohabitation.

Activities of Daily Living↗

Housing issues and realities facing grandparent caregivers who are renters.

PURPOSE: This study determined the prevalence of grandparents raising grandchildren who are living in rental housing and explored the sociodemographic characteristics and challenges faced by such renters. DESIGN AND METHODS: Data were obtained from the Census 2000 Supplementary Survey, a nationally representative survey of 700,000 households with a response rate of 96.8%. Frequencies and bivariate analyses were focused on the 2,639 respondents who were grandparent caregiver renters. RESULTS: Of the 2,350,000 grandparent caregivers in the United States in 2000, 26% were renters, almost one third of whom were spending 30% or more of their income on rent. For the quarter of a million grandparent caregiver renters living below the poverty line, 60% were spending at least 30% of their household income on rent and 3 of 10 were living in overcrowded conditions. IMPLICATIONS: Grandparent caregivers who are renters represent a particularly vulnerable population. The need for further research, policy, and programs for this group is discussed.

Aged↗

Socioeconomic inequalities in cardiovascular mortality and the role of work: a register study of Finnish men.

BACKGROUND: In Finland, socioeconomic inequalities in mortality have been well documented. However, the role of working conditions in the emergence of those inequalities has not been thoroughly examined. METHODS: Data came from the Longitudinal Census file, which included censuses since 1970 (every 5 years). The cohort consisted of men who were in the same occupation in 1975 and 1980, and who were between 25 and 64 years old in 1980. Farm work, mining and military occupations were excluded. Cardiovascular mortality of this cohort was followed up 1981-1994 (5.4 million person-years). Information on marital status, education and income was updated in 1985 and 1990. Working conditions were evaluated at occupational level (job exposure matrix). Poisson regression analyses were conducted to estimate the impact of independent variables on mortality. Inequalities were assessed in relation to occupational class and occupational category. RESULTS: According to the models, elimination of unfavourable working conditions would have reduced the number of all cardiovascular deaths by 8%, myocardial infarctions by 10%, and cerebrovascular deaths by 18%. The most influential job exposures appeared to be high workload, low control, noise, and shift work. Income had a strong effect on mortality. CONCLUSIONS: Working conditions explained a relatively small portion of socioeconomic inequalities in mortality. Inequalities associated with occupational category and class were more attributable to varying levels of education and income.

Adult↗

Trends and disparities in socioeconomic and behavioural characteristics, life expectancy, and cause-specific mortality of native-born and foreign-born populations in the United States, 1979-2003.

BACKGROUND: Immigrants are a growing segment of the US population. In 2003, there were 33.5 million immigrants, accounting for 12% of the total US population. Despite a rapid increase in their numbers, little information exists as to how immigrants' health and mortality profile has changed over time. In this study, we analysed trends in social and behavioural characteristics, life expectancy, and mortality patterns of immigrants and the US-born from 1979 to 2003. METHODS: We used national mortality and census data (1979-2003) and 1993 and 2003 National Health Interview Surveys to examine nativity differentials over time in health and social characteristics. Life tables, age-adjusted death rates, and logistic regression were used to examine nativity differentials. RESULTS: During 1979-81, immigrants had 2.3 years longer life expectancy than the US-born (76.2 vs 73.9 years). The difference increased to 3.4 years in 1999-2001 (80.0 vs 76.6 years). Nativity differentials in mortality increased over time for major cancers, cardiovascular diseases, diabetes, respiratory diseases, unintentional injuries, and suicide, with immigrants experiencing generally lower mortality than the US-born in each period. Specifically, in 1999-2001, immigrants had at least 30% lower mortality from lung and oesophageal cancer, COPD, suicide, and HIV/AIDS, but at least 50% higher mortality from stomach and liver cancer than the US-born. Nativity differentials in mortality, health, and behavioural characteristics varied substantially by ethnicity. CONCLUSIONS: Growing ethnic heterogeneity of the immigrant population, and its migration selectivity and continuing advantages in behavioural characteristics may partly explain the overall widening health gaps between immigrants and the US-born.

Cause of Death↗

Changing area socioeconomic patterns in U.S. cancer mortality, 1950-1998: Part I--All cancers among men.

BACKGROUND: Area socioeconomic deprivation indices are widely used to monitor health disparities in Europe. However, such indices have not been used in cancer surveillance in the United States. We developed an area socioeconomic index to examine area socioeconomic patterns in all-cancer mortality among U.S. men between 1950 and 1998. METHODS: Principal components analysis on 11 census variables was used to develop an area socioeconomic index that was then used to stratify all U.S. counties into one of five socioeconomic categories. The index was linked to 1950-1998 county mortality data to generate annual mortality rates for each area socioeconomic group. Joinpoint regression analysis was used to model mortality trends, and Poisson regression analysis was used to estimate socioeconomic gradients in mortality over time. RESULTS: Area socioeconomic patterns in U.S. male cancer mortality changed dramatically between 1950 and 1998. Throughout the 1950s and 1960s, there was a positive socioeconomic gradient, with higher cancer mortality rates in high area socioeconomic groups than in low area socioeconomic groups. For example, in 1950-1952, cancer mortality was 49% (95% confidence interval [CI] = 41% to 59%) greater in the highest area socioeconomic group than in the lowest. The positive gradient narrowed in the 1970s, and by the late 1980s, socioeconomic differences in cancer mortality began to reverse and widen. In 1997-1998, cancer mortality was 19% (95% CI = 11% to 28%) higher in the lowest area socioeconomic group than in the highest. Gradients were steeper for men aged 25-64 years than for men aged 65 years or older. CONCLUSIONS: Socioeconomic patterns in male cancer mortality have reversed over time in the United States. Area socioeconomic indices could serve as a powerful surveillance tool for monitoring health disparities in cancer outcomes.

Adolescent↗

Relationship between premature mortality and socioeconomic factors in black and white populations of US metropolitan areas.

OBJECTIVE: examined the association of mortality with selected socioeconomic indicators of inequality and segregation among blacks and whites younger than age 65 in 267 US metropolitan areas. The primary aim of the analysis was to operationalize the concept of institutional racism in public health. METHODS: Socioeconomic indicators were drawn from Census and vital statistics data for 1989-1991 and included median household income; two measures of income inequality; percentage of the population that was black; and a measure of residential segregation. RESULTS: Age-adjusted premature mortality was 81% higher in blacks than in whites, and median household income was 40% lower. Income inequality, as measured by the Gini coefficient, was greater within the black population (0.45) than within the white population (0.40; p < 0.001). To confirm that the proxy socioeconomic variables were relevant markers of population health status, regression analysis was performed initially on data for the total population. These variables were all independently and significantly related to premature mortality (p < or = 0.01; R(2) = 0.74). Income inequality for the total population was significantly correlated with premature mortality (r = 0.33). Black (r = 0.26) and white (r = 0.20) population-specific correlations between income inequality and premature mortality, while still significant, were smaller. Residential segregation was significantly related to premature mortality and income inequality for blacks (r = 0.38 for both); among whites, however, segregation was modestly correlated with premature mortality (r = 0.19) and uncorrelated with income inequality. Regional analyses demonstrated that the association of segregation with premature mortality was much more pronounced in the South and in areas with larger black populations. CONCLUSION: Social factors such as income inequality and segregation strongly influence premature mortality in the US. Ecologic studies of the relationships among social factors and population health can measure attributes of the social context that may be relevant for population health, providing the basis for imputing macro-level relationships.

Adolescent↗

Hemochromatosis-associated morbidity in the United States: an analysis of the National Hospital Discharge Survey, 1979-1997.

PURPOSE: The recent discovery of the HFE gene and its association with hereditary hemochromatosis has renewed the attention directed to iron-overload diseases. Population screening for hereditary hemochromatosis is under debate, and population-based estimates of morbidity associated with hereditary hemochromatosis are needed. The purpose of this study is to estimate the number of hemochromatosis-associated hospitalizations in the United States using a population-based dataset. METHODS: National Hospital Discharge Survey and census data were used to estimate hemochromatosis-associated hospitalization rates for persons 18 years of age and over. RESULTS: From 1979 through 1997, the rate of hemochromatosis-associated hospitalizations was 2.3 per 100,000 persons in the United States. The rate among persons 60 years of age and over increased more than 60% during this time period. CONCLUSION: The increase in the rate of hereditary hemochromatosis-associated hospitalizations among older persons is consistent with recent trends in mortality data and may reflect the rising awareness of iron-overload disorders in the United States.

Adolescent↗

Ascertaining the prevalence of childhood disability.

OBJECTIVES: To reapply 1985 Office of Population Census and Surveys (OPCS) disability survey methods, modified as necessary, to a sample of children to ascertain presence of disability. To compare OPCS-based prevalence with prevalence based on carer's views and medical records. DESIGN: Analytical study. Setting Community Child Health Department in UK. PARTICIPANTS: Principal carers of 100 children aged 5-15, selected from a district special needs register. Main outcome measures Comparable information about disability from three sources and diagnosis from carers and medical records. RESULTS: Medical records of 46% contained a diagnosis. Carers were always aware of this, although a single question did not always elicit their knowledge. OPCS-derived threshold disability criteria in categories of Hand function, Personal care, Consciousness and Continence gave prevalence results similar to medical records and carers. OPCS criteria yielded higher prevalence of disability in the areas of Locomotion (8%), Communication (14%) and Hearing (18%). Carers, OPCS and medical records disagreed markedly about prevalence of disabilities of Vision, probably because of the use of differing definitions. OPCS learning criteria were judged unsuitable and standard attainment targets (SATs) were substituted. These provided similar prevalence figures to carers and medical records. OPCS behaviour criteria were also unsuitable and were replaced by the General Health and Behaviour Questionnaire (GHBQ). This found an increased prevalence of problems compared with carers and doctors. CONCLUSIONS: Diagnostic labels have limited use when collecting data about disabled children. Doubt is cast on the validity of some of the 1985 OPCS threshold criteria, and reassessment is suggested before their future use. Further work is needed on the use of SATs and GHBQ in the benchmarking of disability. To collect population data it would be easier and at least equally effective (with caution in the case of Vision) to ask carers directly rather than applying descriptive thresholds and external judgements. Similar information could be obtained from medical records, however, they are likely to be out of date.

Adolescent↗

Relationships between ocular dimensions and adult stature among participants in the Reykjavik Eye Study.

PURPOSE: To examine the relationships between adult stature, age and ocular dimensions in a large homogenous, white population. METHODS: We used the national population census for Reykjavik to select a random sample of adults aged 50 years or older. A total of 846 persons were examined. Scheimpflug images were used to measure anterior chamber depth. Ultrasound was used to measure axial length, lens thickness and vitreous chamber depth. An autorefracto-keratometer was used to measure autorefractive and keratometric values, including the radius of the corneal curvature. Stereo fundus photographs were taken of the optic disc and measurements of the disc diameters were made using computer software. RESULTS: Height correlated positively with axial length in the multivariate model (B = 0.020, 95% CI 0.006-0.034, p < 0.01). Both age and height showed significant correlations with vitreous chamber depth, where the correlation with age was negative (B = - 0.016, 95% CI - 0.006 to - 0.025, p < 0.005) and the correlation with height was positive (B = 0.019, 95% CI 0.005-0.034, p < 0.01). Height also showed a positive correlation with the radius of the corneal curvature (B = 0.008, 95% CI 0.004-0.011, p < 0.001). Anterior chamber depth had a negative correlation with age (B = - 0.013, 95% CI - 0.010 to - 0.016, p < 0.001), whereas lens thickness had a significant positive correlation with age (B = 0.019, 95% CI 0.016-0.023, p < 0.001). We found a significant negative correlation between axial length and refraction/spherical equivalent (r = - 0.595, p < 0.0001). DISCUSSION: Our results indicate that there is a significant relationship between height and several ocular dimensions in this adult population and confirms a negative correlation between axial length and refraction.

Aged↗

Urban-rural disparities in smoking behaviour in Germany.

BACKGROUND: It is currently not clear whether individuals living in metropolitan areas differ from individuals living in rural and urban areas with respect to smoking behaviours. Therefore, we sought to explore the relation between residential area and smoking behaviours in Germany. METHODS: We used a nationwide German census representative for the general population of Germany. A number of 181,324 subjects aged 10 years or older were included. Information on the average daily usage of cigarettes that have or had been smoked formerly or currently was available in subjects who have ever smoked. A daily consumption of more than 20 cigarettes was considered heavy smoking. Logistic regression analyses were performed sex-stratified and adjusted for relevant confounders. RESULTS: Analyses revealed inhabitants of metropolitan areas to be more likely current smokers than inhabitants of rural areas (odds ratio 1.56, 95%-confidence interval 1.51; 1.62). Among current and former smokers those who lived in urban communities had also increased odds for being heavy smokers than those who lived in rural communities. CONCLUSION: We conclude that living in an urban and particularly living in a metropolitan area is a determinant of both smoking and severity of current smoking. Tobacco control programs should recognize the difference in living conditions between rural and urban areas.

Adolescent↗