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PubMed1986

Adenoid cystic carcinoma of Bartholin gland.

Five cases of adenoid cystic carcinoma of the Bartholin gland, a rare vulvar tumor, are reviewed with respect to clinical and pathological characteristics. Histologic transition from normal Bartholin gland to adenoid cystic carcinoma was evident in two cases. Two patients developed the tumor in association with pregnancy. Local recurrences are common and may precede distant metastases, pulmonary being the most common. Patients with repetitive local recurrence or pulmonary metastases may have slowly progressive disease and survive for many years. This is reflected in the disparity between the progression-free interval and survival curves. The recommended primary treatment is wide local excision, obtaining clear margins, and an ipsilateral inguinal lymphadenectomy.

Adult↗
PubMed1985

Adenoid cystic carcinoma presenting as an orbital apex syndrome.

Adenoid cystic carcinomas (cylindromas) are distinctive neoplasms characterized by slow growth, perineural spread, extensive local invasion, frequent recurrence, and high mortality. A case of paranasal sinus adenoid cystic carcinoma presenting as an orbital apex syndrome is described.

Adult↗
PubMed1986

[Primary adenoid cystic carcinoma of the esophagus].

A case of primary adenoid cystic carcinoma of the esophagus is reported, and 45 cases are reviewed. The light and electron microscopic appearances are described in a 77-year-old woman. This patient manifested the intraepithelial spread of cancer cells, which suggested that the tumor arose from the mucosal epithelium of the esophagus. The patient died of mediastinal metastasis 11 months after resection. Adenoid cystic carcinoma of the esophagus is a relatively rare lesion, which exhibits a clinically aggressive behavior. Earlier resection and more intensive chemotherapy will be required.

Aged↗
PubMed1986

Mammary adenoid cystic carcinoma with sebaceous differentiation. A morphologic study of the cell types.

Nine examples of mammary adenoid cystic carcinoma with sebaceous differentiation were studied. Each one of the nine tumors contained basaloid, eosinophilic, and sebaceous cells. Two of these tumors were examined by electron microscopy and compared with four mammary adenoid cystic carcinomas without sebaceous differentiation. The sebaceous cells were similar to normal adnexal sebaceous cells. The eosinophilic cells reflected adenosquamous differentiation and were identical to superficial cells of eccrine sweat ducts. The basaloid cells showed no distinctive cytoplasmic differentiation. Cells with features between the basaloid, sebaceous, and adenosquamous cells were present, indicating that basaloid cells have the potential to differentiate toward skin adnexal structures giving rise to both sebaceous and adenosquamous cells. Myoepithelial cells were not identified in any of the six tumors evaluated by electron microscopy.

Breast Neoplasms↗
PubMed1988

[When should removed adenoids be studied histologically?].

Two children with nasopharyngeal rhabdomyosarcoma are used to discuss the relevance of the histopathological investigation of adenoid tissue. Histopathological investigation should only be omitted if there is complete agreement between symptoms, intra-operative findings and macroscopic findings. Histopathology is advised for very large adenoids, alteration of consistency and in older children or young adolescents.

Adenoidectomy↗
PubMed1987

Unsuspected non-Hodgkin's lymphoma of the tonsils and adenoids in children.

Six children with lymphoreticular malignancy arising in the pharyngeal tonsils or adenoids are presented. Early clues to the possible malignant nature of the enlargement of tonsils and adenoids in this series include: asymmetric and persistent enlargement, the absence of such manifestations of infection as fever or pain, and the association of atypical adenopathy. Lack of clinical suspicion brings with it the risk of delayed diagnosis and possible compromise of optimal therapy.

Adenoidectomy↗
PubMed1985

[Concentrations of antibiotics (josamycin, trioleandomycin and amoxicillin) in the secretions of the ear, sinus and adenoids].

This was a comparative study of antibiotics in the pus of otitis and from the sinuses as well as in the adenoids. Three antibiotics were chosen: Trioleandomycin, Josamycin, Amoxicillin. The study protocol was strict. Results obtained were as follows: high concentrations of macrolids in discharge of otitis and the sinuses as well as in the adenoids. Concentrations were higher than serum concentrations. By contrast, in the case of amoxicillin tissue concentrations were lower than the serum concentration. This leads to the conclusion that there is good penetration of infectious ENT sites by macrolids.

Adenoids↗
PubMedDate not supplied

Basal-cell adenoma of parotid. Difficulty of differentiation from adenoid cystic carcinoma on aspiration biopsy.

Two cases of basal-cell adenoma (basaloid monomorphic adenoma, dermal analogue tumor) seen in a one-year period were subjected to fine needle aspiration biopsy and subsequent histologic confirmation. Two cases of adenoid cystic carcinoma occurring in the parotid region were selected for comparison; a great similarity between the two types of tumors was noted. On aspiration smear both lesions consisted of clusters and sheets of uniform, small, regular cells with scant basophilic cytoplasm and regular round or oval bland nuclei. The smears contained varying amounts of homogeneous, pale, eosinophilic stromal substance within and around the cell clusters. Individual cell differences between the two lesions were minimal, with the adenoid cystic carcinomas tending to exhibit more nuclear hyperchromatism and irregularity; the architectural arrangements of the cell clusters and the stromal substance permitted differentiation between the two lesions.

Adenoma↗
PubMed1980

Mucoepidermoid and adenoid cystic carcinomas of the esophagus.

Four case reports of patients with tumors of the esophagus resembling those of salivary gland origin are presented with a review of the cases published to date. These tumors arise in the submucosal glands in the esophagus and are histologically similar to adenoid cystic and mucoepidermoid carcinomas of the salivary glands. The mucoepidermoid variety occurs more frequently in men than in women, and the adenoid cystic carcinomas are equally distributed between the sexes. In most of the cases reported the tumors were resectable but the overall survival rate is poor and is similar to the rates found with the more frequent squamous cell cancer of the esophagus.

Adult↗
PubMed1980

Ultrastructure of adenoid cystic carcinoma arising in the salivary gland of a child.

A case of adenoid cystic carcinoma which developed in the left parotid gland of an 11-year-old girl was studied by electron microscopy. Islands of tumor cells, showing glandular and cribriform appearances, infiltrated the surrounding tissue and nerves. True lumina and pseudocysts were present in the islands of tumor cells. Electron microscopic examination revealed two types of tumor cells; clear cells (secretory epithelial cells) and dark cells myoepitheium-like cells). Some of the tumor cells, showing a transitional form between the two types, formed a part of the luminal wall. There were many crystalline spicules, cellular debris, and fine stellate granules in the lumina. Pseudocysts were composed of replicated basal laminae, fine stellate granules, and a central core of microfilaments. Rarely, a capillary was noted in the center of the pseudocysts. It is speculated that ultrastrutural features of adenoid cystic carcinoma in chidren may differ from the adult cases in the following ways; they contain numerous crystalline spicules in the lumina, dark cells with microvilli forming the luminal wall, and fine capillaries in the pseudocysts.

Carcinoma, Adenoid Cystic↗
PubMed1981

[Adenoid cystic carcinoma (cylindroma) of the bronchi].

Cytological, histological, and ultrastructural examinations of 6 cases of adenoid cystic carcinoma of the bronchi were carried out. Cytological studies demonstrated cells of two types: smaller, rounded or slightly elongated cells with hyperchromic nuclei and scarce basophilic cytoplasm, and larger cells with clear nuclei and basophilic, slightly vacuolated cytoplasm. The cells are located among oxyphilic homogeneous substance. Histologically the tumour has a typical cribrose appearance owing to glandular-like and cyst-like cavities among alveolar cell aggregates embedded into intensely developed but poor in cells and somewhat hyalinized stroma. The invasive growth of the tumour with its extension into the depth of the lung on interalveolar septae, perivascular and peribronchial spaces with outgrowth of the capsule was manifest in all cases. Electron microscopic studies showed the tumour elements to be lowly differentiated epithelial cells. No ultrastructural signs of myothelium or secretory mucous activity was found. The results of these studies indicate that this tumour should be designated as adenoid cystic carcinoma but not adenoma of cylindromatous type.

Adult↗
PubMed1983

Adenoid cystic carcinoma of lacrimal gland.

Adenoid cystic carcinoma of the lacrimal gland is a relatively rare disease. Only two cases, a man of 61 and a woman of 54 were seen in our clinic from 1962-1981. They presented histopathology of the cribriform pattern characteristic of adenoid cystic carcinoma. The lesion in the male patient belonged to the solid type and was mainly composed of solid nests. It is emphasized that radiotherapy in addition to surgical excision of the tumor is recommended because of its infiltrative nature.

Carcinoma, Adenoid Cystic↗
PubMedDate not supplied

Cytopathologic features of adenoid cystic carcinoma. Case report and literature review.

A case of primary bronchial adenoid cystic carcinoma in a 40-year-old white female is reported. Cytologic findings in a bronchial wash specimen obtained at the time of bronchoscopic examination are described, with an emphasis on correlation with the histologic features of the tumor. The literature is briefly reviewed with respect to the occurrence of primary adenoid cystic carcinoma in the bronchial tree.

Adult↗
PubMedDate not supplied

Benign dermal eccrine cylindroma. A pitfall in the cytologic diagnosis of adenoid cystic carcinoma.

Aspiration cytology from four benign dermal eccrine cylindromas and five adenoid cystic carcinomas were compared. These two lesions were found to have so much in common morphologically that they may be indistinguishable on a purely cytologic basis. Accordingly, we recommend a restricted excision to obtain a histopathologic diagnosis before more extensive surgery is performed whenever a lesion is cytologically consistent with adenoid cystic carcinoma but clinically shows a picture that does not exclude dermal eccrine cylindroma.

Biopsy, Needle↗
PubMedDate not supplied

Primary adenoid cystic carcinoma of the oesophagus.

The light and electron microscopic appearances of a primary adenoid cystic carcinoma of the oesophagus are described in a 70 year old male patient. A large tumour in the lower third of the oesophagus was resected. The tumour exhibited a polypoid appearance and was histologically identical to the previously described adenoid cystic carcinoma of the oesophagus. The patient died 3 months after surgery from widespread distant metastases. These tumours appear to be more aggressive when they arise in the oesophagus than in the salivary glands.

Aged↗
PubMed1980

Persistent adenoid presenting as a nasopharyngeal mass.

A diagnosis of hypertrophied adenoid tissue was confirmed in 12 adults each investigated for a nasopharyngeal mass. The patients ranged in age from 17 to 64 and initially presented with either nasal obstruction or serous otitis media. Four patients had evidence of allergic disease. The development of the lymphoid tissue of Waldeyer's ring is reviewed. Although the adenoid is thought to regress in adolescence, it appears that it can remain hypertrophied and become symptomatic in adulthood. A thorough clinical investigation culminating in biopsy is essential to exclude more ominous pathology.

Adenoidectomy↗
PubMed1980

Influence of upper airway obstruction by enlarged tonsils and adenoids upon recurrent infection of the lower airway in childhood.

The influence of hypertrophied tonsils and adenoids upon ventilation during sleep was evaluated by polygraphic recording before and after adenotonsillectomy. In all 19 cases, esophageal pressure during sleep was elevated as high as 4-6 times normal. This was caused by nasal obstruction due to adenoid hypertrophy and obstruction of the "oral airway" by hypertrophied tonsil and collapse of the tongue due to muscular relaxation during sleep. When minimal amount of contrast media was instilled slowly into the nasopharynx aspiration of the contrast media into the lung was found significnatly more frequently in subjects with upper airway obstruction. Active aspiration of the secretion by marked inspiratory negative pressure during sleep may play a major role in causing recurrent infection of the lower airway frequently seen in these children.

Adenoids↗
PubMed1995

Adenoid cystic carcinoma initially diagnosed and treated as hemangioma.

Adenoid cystic carcinoma initially diagnosed and treated as hemangioma. A case diagnosed as having a hemangioma of the soft palate according to clinical and arteriographic findings is discussed. Recurrence appeared one year after embolization. Arteriography showed no vascular lesion and histopathologic study revealed an adenoid cystic carcinoma. It is stated that imaging studies may be insufficient.

Carcinoma, Adenoid Cystic↗