[Phylogenetic development of the tribes and genera of the subfamily Wurmbaeoideae from the point of view of their contained alkaloids and the migration of continents].
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ABO blood groups, subgroups, M, N and Rh blood types were studied among Bhoksas of Dehra Dun district in Uttar Pradesh. Bhoksas are characterized by high A (33.33%), MN (58.16%), Rz (8.85%), R" (7.86%) and moderately low R1 (43.77%). The present sample does not show differences from the Bhoksas of Nainital but remains differentiated from Majumdar's sample so far as ABO blood groups are concerned. The present Bhoksas also remain undifferentiated from many Mongoloid and other populations of Eastern and Western Himalayas with respect to certain Rh chromosome frequencies. On the whole it is difficult to subscribe to, or reject, Bhoksas' claim of Rajput ancestry. Their differences with Indian Mongoloid populations namely, Bhotias and Tharus suggest that they might not belong to Mongoloid stock.
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Human filariasis was detected in an anthropological and medical survey among the indigenous Mamanwa people of the northernmost region of Mindanao, Philippines in specimens of thin blood smears and cultures of leucocytes from blood samples taken in the day time in September, 1978. Microfilaria positives were 23.2% (22/95) at Bo. Pangaylan, Santiago, 26.7% (28/105) at Kitcharao, Agusan del Norte, 19.3% (16/83) at Urbistondo, Surigao del Norte, Mindanao and none (0/50) at Abucay, Bataan, Luzon. Morphological characteristics of microfilaria were those of Wuchereria bancrofti. The periodicity of microfilaria observed in 3 Mamanwa people was nocturnally periodic with the peak hours at 12 o'clock midnight and the periodicity index at 124.4 following the method of Aikat & Das, or 92.35 following the method of Sasa & Tanaka. Microfilaria positives in the culture of leucocytes were as high as 41.2% (28/68). Since blood samples were taken in the day time and the filaria in these areas was nocturnally periodic, the prevalence of infection among these people is assumed to be much higher than the observed prevalence.
Measles in an unvaccinated virgin population exacted a death toll of 4.2% which fell particularly hard on the age groups which would ordinarily be protected by maternal antibody. The organ system most affected was quite variable. When the virus spread to a largely vaccinated village it caused only one death. Herd immunity seemed to protect many who were not vaccinated. Vaccine failed to protect 7.7% of the recipients. Some of these failures may have been due to erroneous record, vaccination in the presence of maternal antibody or inactivated vaccine, but most occurred in a few family groups related by genetics and similar past immunological experience.
Vaccine induced measles antibody titers in the Upper Xingu Indians remained at satisfactory levels without evidence of decline over a period of six years without re-exposure. However, in another area, a vaccination program which used a reduced dose of vaccine was only 63% effective. When measles virus was introduced to the latter area a protracted epidemic ensued with 23% of the population becoming ill and six deaths. The deaths occurred exclusively under 13 months or over 40 years of age.
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