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T'ao-t'ieh, a motif of Chinese funerary art as the iconographic counterpart of Cinnabar, an alchemical drug.

The agency conferring resurrection is soul or its emblem. The earliest conception of soul is blood. Its Redness penetrates subsoil and is taken up by serpent, from whence arises snake-soul, later snake-god. Blood vapours is the other fraction arising upwards. It becomes wraith bird, later soul bird, and finally bird god. Blood as whole gave snake-god plus bird-god. A winged-cobra became snake-god and bird-god or together, one-as-all. Red Cock was its equivalent. As substance came cinnabar, red like blood and sublimable like soul. Dragon was idealized snake-god. Then Dragon-god plus Bird-god became the equal of blood soul, the magical power. T'ao-t'ieh is Dragon-plus-Bird, snake-god plus bird-god, the equivalent of Cosmic soul. Then cinnabar as the equal of blood soul and T'ao-t'ieh, the emblem of Cosmic soul, each were capable of conferring resurrection and have been interred in Chinese graves.

Alchemy↗

A Thomistic understanding of human death.

I investigate Thomas Aquinas's metaphysical account of human death, which is defined in terms of a rational soul separating from its material body. The question at hand concerns what criterion best determines when this separation occurs. Aquinas argues that a body has a rational soul only insofar as it is properly organised to support the soul's vegetative, sensitive, and rational capacities. According the 'higher-brain' concept of death, when a body can no longer provide the biological foundation necessary for the operation of conscious rational thought and volition, a substantial change occurs in which the rational soul departs and the body left behind is a 'humanoid animal' or a mere 'vegetable.' I argue that the separation of soul and body does not occur until the body ceases to function as a unified, integrated organism. A rational soul is not only the seat of a human being's rational capacities; it is also the principle of the body's sensitive and vegetative capacities. Since Aquinas defines a human being as a composite of soul and body, and not with merely the exercise of rational capacities, the determination of death requires incontrovertible evidence that the body has ceased all the operations that correspond to the soul's proper capacities. The evidence of this is the body's loss of its integrative organic unity and the criterion for determining when this loss occurs is the irreversible cessation of whole-brain functioning.

Brain Death↗

Blood as the earliest drug, its substitutes, preparations and latest position.

Blood was soul and Redness its active principle when red substances were rich in soul-content. But soul was a substance whence blood became a drug which donated soul to treat wounds and incurable diseases. Its redness as life-force, but also as substance, could prolong life. A drug made from human blood could treat serious wounds and as a life saving drug was also a drug of fertility. The latest use of blood appears as syrup haemoglobin while the latest use of human blood would be blood transfusion.

Adhesives↗

Comparing Yin-Yang, the Chinese symbol of creation, with Ouroboros of Greek alchemy.

The universe was early divided into Earth below and Heaven above. These, two as one, gave the idea of opposites but forming a unity. Each opposite was assumed to be powerful and so was their final unity. For creation of the universe they projected reproduction to conceive creation. Now reproduction results in the union of two opposites as male and female. Correspondingly, the Chinese believed Light and Darkness, as the ideal opposites, when united, yielded creative energy. The two opposites were further conceived as matter and energy which became dual-natured but as one. The two opposites were yin-yang and their unity was called Chhi. Yin-Yang was treated separately in Chinese cosmology which consisted of five cosmic elements. Since Chinese alchemy did reach Alexandria probably the symbol Yin-Yang, as dual-natured, responsible for creation, was transformed into a symbol called Ouroboros. It is a snake and as such as symbol of soul. Its head and anterior portion is red, being the colour of blood as soul; its tail and posterior half is dark, representing body. Ouroboros here is depicted white and black, as soul and body, the two as "one which is all." It is cosmic soul, the source of all creation. Ouroboros is normally depicted with its anterior half as black but it should be the reverse as shown here. With the name Chemeia taken to Kim-Iya, the last word would take Ouroboros to Yin-Yang.

Alchemy↗

Vegetative state and brain death: philosophical and ethical issues from a personalistic view.

This article intends to precise the anthropologic fundaments of the Persistent Vegetative State starting from the concept of the human person, as it has been described in relation to the philosophical-theological thought of Thomas Aquinas and other more recent personalists (J. Maritain, E. Mounier, E. Gilson, S. Vanni Rovighi). This view is largely shared by the catholic thought and is present in the Teachings of the Catholic Church. The central point of reflection is in affirming the double unity of the human person: the substantial unity of the spiritual body-soul; the uniqueness of the animative principle (soul) as "form" of corporeity. The spiritual soul is the active principle not only of the superior activities (thought, liberty) but also of the vegetative-sensitive activity of the organism which is part of the person. Thus, as long as a vital unit exists in the individual person, there will exist the presence of a spiritual soul in the organism, defined as a whole unit, and the subject must be considered alive, even when gravely and persistently hindered in the application of his/her cognitive functions.

Brain Death↗

Immediate animation: Thomistic principles applied to Norman Ford's objections.

Norman Ford and other scholars argue that the human embryo cannot have a human soul until after week two of fertilization. They claim that the individuality proper to ensoulment requires the development of the primitive streak and excludes the possibility of twinning. Their arguments are refuted by principles of philosophical realism inspired by Aristotle and Aquinas. According to these principles, the new substance formed by the union of the paternal and maternal DNA has a rational soul. The zygote, to be human, requires a human soul that determines its human development. The primitive streak is part of this development, not a condition of it. Twinning does not disprove the existence of a previous embryo with a human soul. Instead it indicates the existence of a new embryo derived from some totipotent cells that separate from the first embryo.

Beginning of Human Life↗

Gunther von Hagens and Body Worlds part 2: The anatomist as priest and prophet.

Part 1 of this two-part series highlighted tensions between the anatomical quest for scientific knowledge about the human interior and artistic representations of the anatomized body, contrasting the roles of Goethe's scientific Prosektor and humanistic Proplastiker-roles disturbingly fused in Gunther von Hagens. Part 2 first examines religious interpretations of the human body that fuel the tensions manifest in anatomy art. The body in Western cultures is a sacred text amenable to interpretation as handiwork of God, habitation for the soul, and vehicle for resurrection. As handiwork of God the body beckons the anatomist's scalpel, helping establish dissection as the hallmark of Western medicine. The body as divinely designed machine encompasses the idea of an indwelling soul expressing its will in actions mediated through the intricate network of muscles-an understanding reflected in the oft occurring muscle men of early anatomical textbooks. Interconnections of body and soul in medieval somatic spirituality are examined with reference to ideas of resurrection and their impact on anatomical illustration. Part 2 concludes with consideration of von Hagens as priest and prophet, culminating in the Promethean impulse that recognizes not God but ourselves as proper owners and molders of our destiny, embodied in the plastinator's visionary quest to create the superhuman.

Anatomy, Artistic↗

Induction of necrotic cell death and mitochondrial permeabilization by heme binding protein 2/SOUL.

We found that heme-binding protein 2/SOUL sensitised NIH3T3 cells to cell death induced by A23187 and etoposide, but it did not affect reactive oxygen species formation. In the presence of sub-threshold calcium, recombinant SOUL provoked mitochondrial permeability transition (mPT) in vitro that was inhibited by cyclosporine A (CsA). This effect was verified in vivo by monitoring the dissipation of mitochondrial membrane potential. Flow cytometry analysis showed that SOUL promoted necrotic death in A23187 and etoposide treated cells, which effect was prevented by CsA. These data suggest that besides its heme-binding properties SOUL promotes necrotic cell death by inducing mPT.

Animals↗

The first structure from the SOUL/HBP family of heme-binding proteins, murine P22HBP.

Murine p22HBP, a 22-kDa monomer originally identified as a cytosolic heme-binding protein ubiquitously expressed in various tissues, has 27% sequence identity to murine SOUL, a heme-binding hexamer specifically expressed in the retina. In contrast to murine SOUL, which binds one heme per subunit via coordination of the Fe(III)-heme to a histidine, murine p22HBP binds one heme molecule per subunit with no specific axial ligand coordination of the Fe(III)-heme. Using intrinsic protein fluorescence quenching, the values for the dissociation constants of p22HBP for hemin and protoporphyrin-IX were determined to be in the low nanomolar range. The three-dimensional structure of murine p22HBP, the first for a protein from the SOUL/HBP family, was determined by NMR methods to consist of a 9-stranded distorted beta-barrel flanked by two long alpha-helices. Although homologous domains have been found in three bacterial proteins, two of which are transcription factors, the fold determined for p22HBP corresponds to a novel alpha plus beta fold in a eukaryotic protein. Chemical shift mapping localized the tetrapyrrole binding site to a hydrophobic cleft formed by residues from helix alphaA and an extended loop. In an attempt to assess the structural basis for tetrapyrrole binding in the SOUL/HBP family, models for the p22HBP-protoporphyrin-IX complex and the SOUL protein were generated by manual docking and automated methods.

Amino Acid Sequence↗

Descartes and the pineal gland in animals: a frequent misinterpretation.

René Descartes presented a number of reasons for his choice of the pineal gland as a logical place for the soul to interact with the physical machinery of the body. It is often stated that one of his reasons was that he believed animals do not have pineal glands, whereas humans alone possess a soul and this small structure. This is a misinterpretation of Descartes. The philosopher knew that barnyard and other animals possess pineal glands, having seen this with his own eyes. His point was that the pineal is unique in humans only because of a special function - acting as the seat for the rational soul.

Animal Population Groups↗

A comparative study of greek and chinese alchemy.

According to an herbal cult of immortality in China, about 200 B.C., certain plants could make man immortal. Greek alchemy, the earliest record of which dated about 200 A.D., presents a similar version, was originally Chinese and was introduced by the Arabs who brought herbal drugs of longevity to Alexandria. The name of these drugs, Chin-I, dialectal Kim-Iya, was Arabicized as Kimiya and transliterated Chemeia by the Copts. Other terms were later influenced by Indians (Chumeia, 100 A.D.) and more directly by the Chinese (Chrusozomion, 200 A.D.). The 3 terms signify herbal elixirs of gold and the art related to them. Both early Chinese and Greek alchemies were not concerned with the making of bullion gold. In China the development of alchemy has been ruled by two theories: first, as like makes like, a perennial plant can make human life perennial: likewise, certain substances can prolong human life as they are rich in Life-force or Soul-content. From here, Blood was equated to Soul and later Redness to Soul. Jade, Cinnabar and eventually gold, more precisely Red-gold or Cinnabar-gold, a colloidal gold, became the ideal drug of immortality. Finally, alchemy can be defined as the art of making metal colloids as panaceae.

Alchemy↗

The Chinese representation of cosmic elements as graphic symbols.

In Chinese cosmology, cosmic elements have been deified and assigned life-forms. Air, representing ultrasonic energy as a celestial entity, became bird-god, Red-bird. Water acquired Dragon as its representative and Fire had Tiger as its graphic symbol. Earth, as body, was fertile and long-lasting. It was symbolized as Tortoise, known to be long-lived. Its soul became Serpent, long enough to be powerful as Cosmic soul. Serpent-Tortoise, as Body-Soul, became the god Black-Warrior in charge of Earth.

China↗

The nature of life in the history of medical and philosophic thinking.

The vitalistic doctrine of Aristotle and Galen, in which the soul is an indissoluble part of the body, was undisputed throughout most of the Middle Ages. The first radical change came with Telesio, who developed philosophic naturalism in which the soul has a reality of its own, though it is connected to the body. The definitive change came with Descartes, who believed that all biologic phenomena can be explained by the laws of mechanics, and only man is distinguished by the possession of a soul. For the next 300 years, this mechanistic view would be challenged by a new vitalism, in which the 'vital force' has an existence in its own right.

Europe↗

Medicine and moral virtue in the Expositio Problematum Aristotelis of Peter of Abano.

This paper examines a set of questions concerning moralia in Peter of Abano's Expositio Problematum (1310) and shows that its author takes a naturalistic approach, heavily reliant on medical doctrine, to propose that not only the lower virtues, but also those dependent on the rational soul, are closely tied to physiological states. For the irrational soul, this close connection with the body is not surprising. However, in the case of the rational virtues, the dependence on the body is more unusual and offers a significant example of Peter's application of medical doctrine beyond the established bounds of the discipline. His is a very different approach to human virtue than that of his contemporaries, and it blurs the distinction between moral virtue and natural virtue throughout his exposition. At the same time, this commentary offers insight into Peter's broader position on the soul.

History, Ancient↗

Spiritual psychotherapy.

The author proposes the practice of spiritual psychotherapy, which transcends but does not preclude traditional modalities or strategies of treatment. The terms soul and spirit are distinguished as different transpersonal abstractions, yet are inextricably linked. The former aims at revealing the mystery of relatedness and intimacy in everyday life, the latter at finding the divine in universal life. For the spiritual therapist, these concepts are applied to a therapeutic context of care and compassion--which means love and belief beyond oneself. More specifically, the way to soulfulness requires Love of Others, Love of Work, and Love of Belonging, whereas the way to spirituality requires Belief in the Sacred, Belief in Unity, and Belief in Transformation. By cultivating a soulful and spiritual existence, thus conducting one's clinical practice on the basis of these six tenets of transcendence, the therapist can guide the patient to reach his or her own authentic self.

Humans↗

Psychology and mind in Aquinas.

This article stresses the main lines of Thomas Aquinas's philosophy on the nature of the body-soul union. Following Aristotle, Aquinas sees the soul as a 'principle of life' which is intimately bound to a body. Together they form a non-contingent composition. In addition, the distinctive feature of the human soul is rationality, which implies that a human needs a mind to be what it is. However, this is not to say, as Descartes proposes, that the reason that I am a human is that I am fully self-conscious. On the contrary, I will show that self-consciousness is not necessarily a key to defining a human being. To that aim, and based on Aquinas's views, I draw a distinction between what I will call 'egos' and selves'.

Consciousness↗

[Care for the incurable elderly].

The goals of medicine encompass the relief of pain and suffering, the promotion of health and the prevention of disease, and the cure of disease when possible and the care of those who can not be cured. Today, closely affiliated with various establishments, medicine sustains an influential but strange subculture in our society. Because of its insistent ideology for cure, medicine is blamed for futility, a misuse of modern technology. The root of the problem lies in the abandonment of the human soul when medicine in the 19th century joined the new-sprung science which identified objectivity as a leading principle forbidding "cogito ergo sum". Accordingly, modern medicine neglected patients for whom the care of the mind is essential and failed to care for those with uncurable conditions. Curiously, the development of life sciences dictates the human soul as a final product of an evolution through a trade-off with aging and death. The human soul and its dignity must be revived at the heart of medicine, and the art of dying must be sought to enable a peaceful death. The concept of Tenju gann or "natural-end cancer", an example for blessed longevity followed by a peaceful death is an ideal goal of palliative care, developing the art of dying for every patient, irrespective of age or disease. Palliative care begins at the irreversible stage of diseases or when treatment impairs the dignity of a dying patient. With public disclosure physicians must be selected by aged patients and their families to promote the art of dying.

Aged↗

The wounded male persona and the mysterious feminine in the poetry of James Wright: a study in the transformation of the self.

James Wright's work is multilayered. Taken as a whole, which Annie Wright's beautiful compilation, Above the River, allows one to do, Wright's poems (as well as his masterful "prose poems") have a pattern akin to a mythic cycle. "Mythemes" (Lévi-Strauss, 1979) recur as dialectic opposites from one poem to another, whether the abandoned male and mysterious woman, humankind and nature, blindness and seeing, secrets and revelation. Suggestive and symbolic forms such as birds, horses, earth, sky, the destitute, rivers, and adolescence weave themselves throughout in inner and outer "landscapes" of images and experiential moments. There is a frequent shift of "gestalts" between the inner world and external reality. Such a "blooming, buzzing confusion" of internal and external referents might appear to be psychotic and imply a loss of "reality testing." Chassaguet-Smirgel (1988), citing Oscar Wilde's The Picture of Dorian Gray as an example, contended that the artist narrowly averts psychosis by transforming it into a work of art. Surrealists, for whom the psychoanalyst Jacques Lacan was an important figure (cf. Sarup, 1992, pp. 17-27), elevated psychosis to the status of art, and Wright has been considered to be a surrealistic poet, although he himself denied such an affiliation. Hall (Wright, 1990, Introduction, pp. xxiii-xxxvii) suggests that Wright, in addition to an extensive history of alcoholism, from which he seemed to recover towards the end of his life, suffered from a major mental illness, which included episodes of severe depression, hospitalizations, and at least one suicide attempt. The severity of the asceticism and the extreme damage to the self in some Wright's work suggests their roots in early traumatic experiences. (A terribly damaged yet heroic personage, whose disfigurement perhaps symbolizes the poet's trauma, is "Hook" [ATR, pp. 315-316], about a man who gives his last few cents to the poet with a hook replacing his amputated hand.) Not enough is known about Wright's childhood to attempt to reconstruct such a trauma, and a definitive biography is long overdue. (Wright died in 1980). However, the concept of "soul murder" as used by Shengold (1989) with respect to psychological trauma does seem pertinent. For example, Wright's powerful identification with the downtrodden, and especially with certain murderers (Doty, Judas) echoes the paranoiac Schreber's identification with his abusive father as "soul murderer": "I, myself, have been 'represented' as the one who had committed soul murder" (Shengold, 1989, p. 22, quoting Schreber). Certainly, the theme of damage to the self is prominent in Wright, and the poet's striving for reparation, restitution, and the restoration of lost goodness is not only characteristic of Melanie Klein's "depressive position" (Segal, 1980, pp. 76-89), which she saw as a normal developmental process, but also of the character structures of profoundly traumatized individuals. In addition, the rapid, "leaping" shifts of imagery in Wright's poems bear some resemblance to the shifts in mood and the dissociated and "autohypnotic" states (Shengold, 1989, pp. 138-154) of posttraumatic stress and related disorders. However much that may be the case, Wright's work moves toward healing and integration, and forces us to reconsider the psychoanalytic shibboleth that all that represents a lack of distinctiveness between self and other is pathological. This assumption denies the richness of that part of the psyche which originates in the symbiotic union of mother and infant. Wright's work does not so much force us to doubt our own perceptions of reality as it gently yet forthrightly guides us into other realms where feeling and thought are in dialogue, where the uniquely human and the universal mythos converge, and where--perhaps most importantly--possibility and transformation are imminent. The abandoned male persona and the mysterious feminine are part of that world, that cosmos, that Wright has cr

Female↗