Search PubMed⌕ Search

SEARCH · Search PubMed

Results for “Postphlebitic Syndrome”

Search indexed PubMed citations on genomics, clinical trials, systematic reviews and public health. Explore titles, authors and supplied subject terms, then open the PubMed record.

Quote a phrase for an exact phrase match. Source license links do not imply unrestricted reuse.

At least 721 records · Page 40Linked to original sources
PubMed1986

[Phleboscintigraphy in the diagnosis of diseases of leg veins].

The authors worked out the methods of staged radionuclide phleboscintigraphy and defined its clinical importance for examination of patients with chronic venous insufficiency of the lower limbs using a gamma-chamber without an image synchronized with a moving table. Altogether 26 patients with various forms of lower limb venous insufficiency were examined. A normal phleboscintigram and radionuclide semiotics of the main lesions of the lower limb veins were described. The method of staged radionuclide phleboscintigraphy permits one to obtain a good image of the iliofemoral venous segment and vena cava inferior in minimum radiation exposure and traumatism.

Adult↗
PubMed1995

Microcirculation in high perfusion microangiopathy.

Using laser-Doppler flowmetry in association with other noninvasive microcirculatory techniques such as transcutaneous PO2 and PCO2 and capillary filtration measurements it is possible to define two major types of microangiopathy. Low perfusion microangiopathy (LPM) is observed in peripheral vascular disease, essential hypertension, Raynaud's disease etc. High perfusion microangiopathy (HPM) is observed in venous hypertensive microangiopathy and diabetic microangiopathy. In both these conditions there is an increased skin flux, decreased venoarteriolar response and increased capillary filtration leading to edema formation. In HPM elastic compression and drugs acting on capillary filtration effectively reduce skin flux and the increased capillary leakage and edema formation.

Bandages↗
PubMed1995

[Late results of the Palma operation].

Since 1981, 54 femoro-femoral crossover saphenous bypass (Palma-operation) were performed for chronic venous insufficiency caused by unilateral iliac vein occlusion. Long-term patiency rate and clinical results were evaluated by radioisotope venography and venous occlusion plethysmography. Plethysmography demonstrated significant improvement of maximal venous outflow after operation. Radioisotope venography showed remarkable long-term patency rate of Palma-bypass (of 42 operation, 29 patent graft). Long-term clinical results appeared to be excellent after operation of isolated iliac vein occlusion, whereas the results after operations performed with postthrombotic changes in more distal deep veins were not acceptable, therefore a more critical preoperative selection seems to be necessary.

Adult↗
PubMed1994

Morphological changes of dermal blood and lymphatic vessels in chronic venous insufficiency of the leg.

Morphological changes of dermal blood and lymphatic microcirculation in skin biopsies from patients affected by Chronic Venous Insufficiency (CVI) associated with stasis dermatitis of the lower limbs, are reported here. Blood vessels are characterized by an occluded lumen, thickening and reduplication of the basement membrane. The structural changes in dermal lymphatic vessels are: (i) collapsed lumen of lymphatics located in the papillar dermis; (ii) numerous and complex interdigitations between contiguous endothelial cells and lack of open junctions; (iii) derangement of the anchoring filaments that normally pull the lymphatic lumen open. The connective matrix is characterized by fibrosis with formation of dense bundles of collagen and elastic fibers. These results suggest that the dermal lymphatic and blood microcirculation in CVI are connected to a reduced fluid exchange capacity because of the structural changes occurred in the vascular and lymphatic wall and in the surrounding connective tissue.

Biopsy↗
PubMed1995

Are peripheral lymphatics damaged by high pressure manual massage?

Massage of the foot in men and the hindpaw in dogs was performed by applying external pressures of 70-100 mmHg for a period of one, three, five, and ten minutes with a frequency of 25 strokes per minute. This protocol was performed on individuals without edema, on dogs with experimental lymphedema and men with post-thrombotic venous edema. After ten minutes of forceful massage, focal damage of lymphatics was present. In a group of dogs with lymphedema and men with post-thrombotic venous edema, the alteration of lymphatics was greater than in normal individuals and evident only after 3 to 5 minutes of massage. At first, the forceful massage affected the endothelial lining of the initial lymphatics. Alterations of lymphatic collectors were visible later. The fluid in lymphedema was translocated by massage using high pressure from the interstitium into the lumen of lymphatics by means of the open junctions and by artificial cracks that develop from injury to the lymphatic wall. Vigorous massage in lymphedema also produces loosening of subcutaneous connective tissue, formation of large tissue channels and release of lipid droplets that enter the lymphatics. By this mechanism, massage helps reduce the amount of fat cells in the lymphedematous leg.

Adult↗
PubMedDate not supplied

[Ambulatory treatment of postphlebitic ulcers of lower limbs. Physiopathological bases and clinical results].

Venous ulceration is a troublesome and disabling complication, representing one of the most difficult problems to be treated by the vascular surgeon. Venous insufficiency is a widespread condition, the prevalence of venous ulceration being 0.5 - 1 per cent in European populations. Although all venous ulcers will heal if the limb is elevated above heart level for an extended period of time, patients need a safe, effective, not disabling and quick therapy. Hence, the competent vascular surgeon must be familiar with venous pathophysiology and possess a thorough understanding of the treatment options available for a discouraged patient in need of an acceptable and effective approach. The aim of the present study was to assess the efficacy and the speed of healing of venous ulcer using an outpatient ambulatory treatment protocol. This protocol consisted of elastic compression bandage allowing deambulation, local dressing using lyophilized heterologous collagen (Condress, Gentili) and systemic profibrinolytic drugs. Exclusion criteria were coexisting arterial insufficiency, ulcer area greater than 25 cm2, coexisting disabling diseases (congestive cardiac failure, hepatic insufficiency, malignancy). From December 1990 to June 1993, 37 patients affected by venous ulcer were treated, according to the aforementioned protocol, at the Surgical Department of Montecchio Maggiore Hospital (VI). There were 16 male and 21 female patients, mean age was 66 years (range 59-91). Results show the complete healing of the venous ulcer in 94.5% of patients; mean time for ulcer healing was 128 days (range 45-91). The Authors conclude that the outpatient ambulatory treatment protocol is safe, quick, and effective for the therapy of chronic venous ulcer; once obtained the healing of the ulcer, elastic compressive bandage with elastic stockings is mandatory to prevent recurrences.

Aged↗
PubMed1994

[The current concept of the pathogenesis of trophic skin lesions in chronic venous insufficiency from the morphologic viewpoint].

Disturbances of the venous macrocirculation are the main cause of trophic skin lesions in primary and secondary chronic venous insufficiency. The microcirculatory process initiates with functional and organic endothelial alterations in the cutaneous and subcutaneous capillaries, followed by increased permeability for blood plasma and erythrocytes, and later by edema and micronecroses in the interstitial tissue. Subsequently a reactive chronic inflammation develops. A vicious circle consisting of repeated tissue necrosis alternating with repair processes and later with tissue fibrosis may develop. This injury and repair process is non-specific and characteristic for all types of tissue necrosis. Intensity and duration of the process depend on degree and persistence of the underlying disorder.

Capillary Permeability↗
PubMed1994

[Micromorphologic changes in the skin in primary and secondary (post-thrombotic) chronic venous insufficiency].

The micromorphological alterations in chronic venous insufficiency are characterized by a patchlike distribution. At least in the initial stages, normal skin areas may alternate with regions containing severe alterations. The capillaries may be rarified, or elongated and dilated with formation of glomerulus-like clusters, or they may show proliferation within a granulomatous repair tissue. Pericapillary accumulation of fibrin may be observed only within necrotic tissue surrounding an ulcer. The pericapillary space which is enlarged and edematous in chronic venous insufficiency, cannot be anatomically defined. The interstitial tissue may contain a secondary chronic inflammation with repair function. Finally a hyaline scar tissue with so-called "avascular" fields and dystrophic calcification/ossification may result.

Capillaries↗
PubMed1994

[Significance of cutaneous microangiopathy for the pathogenesis of dermatitis in venous congestion due to chronic venous insufficiency].

Skin damage due to chronic venous insufficiency is preceded by severe microangiopathy of skin. With increasing clinical symptoms like edema, hyperpigmentation, induration, ulcer and atrophy blanche number of nutritive capillaries and transcutaneous oxygen-tension decreases, transcapillary, and interstitial leakage increases and cutaneous vascular reserve disappears. These congruent results were found by means of capillaroscopy, fluorescence-videomicroscopy, transcutaneously measured oxygen partial pressure and Laser Doppler Fluxmetry. Most of capillaries are elongated and tortuous, especially in ulcer stage they look glomerular. Compared to pin-shaped capillaries glomerular capillaries contribute less to nutrition because of functional AV-shunts. As dilated capillaries are already seen in skin areas without any trophic skin changes, cutaneous microangiopathy seems to be first consequence of venous hemodynamic disturbances which then is followed by skin disease. As severe microangiopathy still remains after healing of ulcer, it explains frequent recurrencies.

Blood Flow Velocity↗
PubMed1994

Incidence and time of occurrence of valvular incompetence following deep vein thrombosis.

Commencing December 1986 and over the course of 4 years, the diagnosis of acute deep vein thrombosis (DVT) was established by duplex scanning in 286 patients referred to the University of Washington Medical Center in order to rule out this problem. From this group 107 patients (123 legs with DVT) were placed in a long-term follow-up program. The documentation of valvular reflux and its site was demonstrated by duplex scanning. The duplex studies were done at intervals of 1 and 7 days, 1 month, every 3 months for the first year and then yearly thereafter. The mean follow-up time was 341 days. The presence of reflux was also determined in 502 patients with a negative duplex study and no previous history of DVT or chronic venous insufficiency. In the patients with acute DVT, valvular incompetence was noted in 17 limbs (14%) at the time of the initial study. Reflux was absent in 106 limbs (86%). In this last group reflux developed in 17% of the limbs by day 7. By the end of the first month, 37% demonstrated reflux. By the end of the first year, more than two-thirds of the involved limbs had developed valvular incompetence. The distribution of reflux at the end of the first year of follow-up was: 1) popliteal vein, 58%; 2) superficial femoral vein, 37%; 3) common femoral vein, 33%; and 4) posterior tibial vein, 18%. Reflux in the greater saphenous vein occurred in 25% of the limbs after 1 year. Reflux developed more frequently in thrombosed venous segments.(ABSTRACT TRUNCATED AT 250 WORDS)

Adolescent↗
PubMed1994

[Discussion comment: surgical therapy of thrombosis of leg and pelvic veins].

Referring to a survey of the literature and the own clinical series the open problems in the surgical treatment of acute iliofemoral venous thrombosis are discussed. Only 2 reports have been published, which test 2 therapeutical options, surgery versus oral anticoagulant treatment in a randomised trial. Nevertheless there have been some shortcomings. Therefore a further clinical trial, with multicentre design, probably guided by a scientific society, seems justified to settle the remaining questions.

Femoral Vein↗
PubMed1994

[Combined compression and electric stimulation therapy].

The use of compression- or Neuromuscular electrostimulation therapy (NMES) for the treatment of venous and lymphatic disorders has been known for a long time. Furthermore, NMES is being used for the treatment of arterial circulatory disorders as well as for neuromuscular lesions. More and more often, external pneumatic intermittent compression therapy is being used for the prophylaxis of postoperative thromboembolic complications. If both methods are used simultaneously, a synergic effect is being obtained, where as the possible deficits of one technique are being counteracted by the advantage of the other. The KKRT is being described and the outcome of 2 trials performed in gynecological and dermatological field is being presented.

Aged↗
PubMed1994

[Surgical therapy of ulcus cruris. Significance of extension of the damage to deep veins for incidence of ulcus cruris recurrence].

2 retrospective studies illustrate the importance of the extent of damage to the deep venous system governing the recurrence rate of stasis ulcers treated surgically. 1. In patients with recurrent venous stasis ulcerations associated with superficial varicosis of the great or lesser saphenous veins and incompetent perforators operative treatment of the varicose veins resulted in a 100% long-term healing rate of the ulcerations (5-year results). This was the case for 25 legs with venous ulcers in 229 consecutive cases operated for varicose veins. 2. In 76 patients with rebellious ulcers presenting without operable superficial varicose veins the treatment was a localized one consisting of wide and deep excision of the ulcer with ligature of underlying perforators and surrounding varicose veins. The 2-year success rate was 87% in 39 patients with intact deep veins, but only 59% in 37 patients with postphebite damage to the deep veins (p < 0.05). For 1 and 2 level deep vein disease the success rate was still high at 80%, but fell to 20% if damage to the deep veins extended to 3 or 4 levels! Thus, the degree of damage to the deep veins correlates well with the propensity to recurrence of venous ulceration following surgical treatment. Venous hypertension measured by phlebodynometry is the single most powerful predictor of success or failure of surgical treatment. Patients at risk should therefore be encouraged to wear compression stockings or hosiery to offset recurrencies.

Follow-Up Studies↗