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Does porosity matter?

Patients who had survived at least four years after aortic aneurysmectomy were divided into two groups depending on the prosthesis being of woven or knitted fabric. Such prostheses do not develop an endothelial lining in man, and remain thrombogenic despite their great practical success. A comparison of the persistence versus the loss of palpable pulses distal to the prosthesis, was taken as an index of thrombogenicity and the formation of micro-emboli. There was a statistically significant difference in the persistence of distal pulses in patients with knitted grafts in the 5th, 6th and 7th years of the study, suggesting that such grafts are less prone to thromboembolic activity than the woven prostheses.

Animals↗
PubMed1983

[Small-caliber arterial prostheses: influence of porosity].

Thirty-two pyrolytic carbon coated Weavenit dacron grafts and 32 human umbilical vein segments treated with glutaraldehyde were implanted in the carotid arteries of 32 dogs. Prosthesis samples were removed after periods varying from 10 to 120 days, and sections examined by optical microscopy. Internal surfaces were studied by scanning electron microscopy. Overall permeability was 93.7 p. cent for the dacron prosthesis and 84.3 p. cent for human umbilical vein sections. Fundamental stages of the pseudointimal organization process were compared for the two types of prosthesis.

Animals↗
PubMed1983

[Small-caliber arterial prosthesis: effect of porosity].

Thirty-two pyrolytic carbon-coated weanenit Dacron grafts and 32 segments of human umbilical vein treated with glutaraldehyde were implanted into the carotid arteries of 32 dogs. Prosthesis segments were removed after intervals of from 10 to 120 days and sections examined by standard optical microscopy, and the internal surfaces by scanning electron microscopy. Overall percentage permeability was 93.7 p. cent for Dacron prostheses and 84.3 p.cent for human umbilical vein sections. Fundamental stages of pseudo intima organization were compared for the two types of prosthesis.

Animals↗