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At least 721 records · Page 40Linked to original sources
PubMed1995

Mechanism of colloidal particle uptake into the lymphatic system: basic study with percutaneous lymphography.

PURPOSE: To examine the extracellular (dispersed particles) and intracellular (phagocytosed particles) colloidal particle transport from subcutaneous tissue into the lymphatic system. MATERIALS AND METHODS: Perfluorocarbon emulsions LA11063 (mean particle diameter, 0.34 micron) and ZY12149 (mean particle diameter, 0.06 micron) were individually injected into the dorsal skin of the hind foot of rabbits. Lymph flow rates and particle concentrations were determined in prenodal lymph fluid after injection, with and without massage of the skin over the injection site. RESULTS: In the first 24 hours after injection, extracellular colloid flux was substantially larger than intracellular flux. Lymph flow rates and colloid concentrations increased substantially with massage. Extracellular LA11063 flux was smaller than ZY12149 flux, whereas intracellular LA11063 flux exceeded ZY12149 flux. CONCLUSION: Transport of colloids into lymphatic vessels is dependent on particle size. Both extracellular and intracellular pathways are utilized. External tissue movement contributes substantially to the rate of particle uptake via both pathways.

Animals↗
PubMed1984

[Value of computed tomography and lymphography for the demonstration of pelvic lymph node metastases in prostatic cancer].

Between 1977 and 1982 74 patients with cancer of the prostate underwent a pelvic lymphadenectomy. 17 had a preceding lymphangiography and 25 computerized tomography; the sensitivity of the former was 50%, the specificity 56% and the accuracy 53%, whereas the latter produced rates of 25, 100 and 76%, respectively. These percentages are in keeping with the literature. In addition, 61 of the 74 patients had during the lymphadenectomy a frozen section, which was in 87% accurate, but yielded a false negative ratio of 32%. The efficiency is within the figures given in the literature.

Evaluation Studies as Topic↗
PubMed1989

Tumor volume, CT scan, lymphography, sonography, intravenous pyelography, and tumor markers in testis tumors.

Correlation of tumor volume to tumor stage in 134 patients with nonseminomatous testicular tumors, which were classified according to the TNM system, revealed similar tumor load for N0 and N1 patients. CT scans (n = 92), lymphangiography (n = 47), intravenous pyelography (IVP) (n = 134), sonography (n = 118) and serial tumor markers (n = 82) were evaluated for sensitivity, specificity and accuracy, both separately and in different combinations. The best individual results were obtained by lymphangiography (sensitivity 0.77, specificity 0.73, accuracy 0.75) and CT scan (sensitivity 0.52, specificity 0.91, accuracy 0.70). In combination CT scan and lymphangiography were the most valuable diagnostic tools (accuracy 0.79) with high sensitivity (0.88) and specificity (0.77). For patients with negative CT scans, subsequent lymphangiography is recommended for accurate staging, as seems mandatory in stage 1 patients entering surveillance programs.

Adult↗