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At least 721 records · Page 40Linked to original sources
PubMed2000

Thermal Intermolecular Hetero Diels-Alder Cycloadditions of Aldehydes and Imines via o-Quinone Dimethides This work was supported by the National Institutes of Health (AI 16943/CA 28824). Postdoctoral Fellowship support is gratefully acknowledged by M.F.H. (5T32 CA62948-05) and J.G.A (NIH, CA-80356). We are grateful to Dr. George Sukenick (NMR Core Facility, Sloan-Kettering Institute) for NMR and mass spectral analyses.

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Journal Article↗
PubMed2001

Benzylic Imine Catenates: Readily Accessible Octahedral Analogues of the Sauvage Catenates This work was supported by the EPSRC. D.A.L. is an EPSRC Advanced Research Fellow (AF/982324). We thank Dr. B. P. Murphy (Manchester Metropolitan University) for useful discussions and Drs. T. J. Kidd, S. M. Lacy (University of Warwick), G. Di Orazio and R. Nasreen (University of Manchester, Institute of Science and Technology) for early ligand design.

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PubMed2001

Highly Enantioselective Allylation of Imines with a Chiral Zirconium Catalyst This work was partially supported by a Grant-in-Aid for Scientific Research from the Ministry of Education, Science, Sports, and Culture, Japan. The authors are grateful to Dr. Motoo Shiro (Rigaku Co. Ltd.) for his help in performng the X-ray analysis of compound 3 cd. T.G. thanks the Japan Society for the Promotion of Science (JSPS) for the award of a postdoctoral research fellowship.

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PubMedDate not supplied

[Anti-ulcerogenic action of a combination of a psychostimulator of the phenylalkylsydnone imine series and arginine].

It has been revealed that OF 743, one of the psychostimulators belonging to phenylalkylsydnonimine derivatives, exerts anti-ulcerogenic action in case of stress- and ethanol-induced damage of gastric mucosa in rats. However OF 743 was not effective in case of indomethacin-induced gastric mucosal damage. Complex administration of OF 743 and arginine was accompanied by a considerable decrease of indomethacin-induced gastric mucosal damage. That combination was more effective than OF 743 alone in case of ethanol-induced gastric mucosal damage.

Animals↗
PubMed1988

[Characteristics of the mutagenic and toxic effects of ethylene imine and its oligomers. Comparative study in the automated SOS-chromotest system and in standard bacterial test systems].

Raising total positive charge of a chemical mutagen does increase its local concentration in the area of biological target-DNA, and, as a consequence, causes increase in the rate of interaction of a mutagen with the target. Experimental evidence of this idea has been obtained in three test systems: the Ames test, Trp+ reversions in Escherichia coli WP2 and in the automated "SOS-chromotest" system with E. coli PQ 37 ("Labsystems", Finland).

Aziridines↗
PubMedDate not supplied

[Anti-ulcerogenic properties of psychostimulants of the phenylalkylsydnone imine series].

In rats, administration of 96% ethanol to the stomach causes ulcerative damages to its mucosa just 8 minutes later, which are of significant dimensions, reaching their maximum size following 3 hours. The sydnonimine psychostimulant OF-743 in combination with ethanol substantially reduces mucosal damage. The use of ethanol after OF-743 injections results in less ulcerative damage. The findings suggest that the drug has not only protective (preventive) effects, but beneficial properties.

Animals↗