[PRIMARY CARCINOMA OF THE FALLOPIAN TUBE].
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Animals↗
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Primary fallopian tube carcinoma - the experience of a UK cancer centre and a review of the literature.
Primary fallopian tube carcinoma (PFTC) is rare but may be under-diagnosed. We have analysed the incidence, clinical findings and outcome in patients with PFTC at the RUH Gynaecological Cancer Centre in Bath between 1999 and 2004, and compared the incidence with that of advanced ovarian carcinoma (OC). Eight patients had PFTC, seven of whom were diagnosed after 2001, and 55 patients had advanced OC. Our data suggest a relative increase in the number of patients with PFTC over the study period. PFTC patients had a mean age of 69.6 years, most presented with postmenopausal bleeding, two had a second carcinoma, three were nulliparous and none were diagnosed pre-operatively. All were treated surgically and received platinum-based chemotherapy. Although PFTC patients had better outcomes than those with advanced OC, the difference was not statistically significant (p = 0.088). Accurate diagnosis and differentiation of PFTC from advanced OC are important for monitoring trends in incidence, for better characterisation of prognostic features and improved management.
Age Distribution↗
Tubal pregnancy following tubal embryo transfer into the contralateral fallopian tube.
Ectopic and heterotopic pregnancy may occur with increased frequency following assisted reproductive technology (ART) procedures. In addition, there may be unusual sites of implantation, which may cause atypical and confusing clinical manifestations. We present a case of tubal pregnancy after tubal embryo transfer (TET) to the contralateral fallopian tube. Four embryos were transferred to the left fallopian tube by laparoscopy, but the patient developed a right tubal pregnancy, possibly as a result of intrauterine or intra-abdominal migration of the embryo. ART patients must be followed closely soon after the procedure, and there should be a high index of suspicion for an unusual implantation site.
Adult↗
A new concept for anastomosis of the fallopian tube: tissue reconstruction with nonpenetrating, arcuate, legged clips in the rat model.
OBJECTIVE: To evaluate the titanium Kirsch-Zhu microclip microsurgical reanastomoses of the fallopian tubes. DESIGN: Compare the reanastomoses of the rat uterine horn between Kirsch-Zhu clips (Cushman Engineering, Albuquerque, NM) (group A) and conventional suture microsurgical techniques (group B). SETTING: Microsurgery Research Laboratory, Loma Linda University Medical Center, Loma Linda, California. PATIENTS, PARTICIPANTS: Fifteen SD rats Harlan (Harlan Sprague-Dawley Corp., Indianapolis, IN) were done in groups A and B and six in control group (C). MAIN OUTCOME MEASURE: Pregnancy rate, litter size, tissue of procedure, and histologic results. RESULTS: The clip technique was shorter in procedure time and resulted in equal fertility rate and litter size. Histologically, there were less granulomatous formation and histiocytic inflammation, but muscularis thinning and fibrosis were noted with the clip. CONCLUSIONS: The Kirsch-Zhu clip has potential for application to human fallopian tube reanastomoses.
Anastomosis, Surgical↗
Prolonged survival in two cases of carcinoma of the fallopian tube presenting after hysterectomy: case reports.
Two patients presented with fallopian tube carcinoma after hysterectomy. Both have had a prolonged survival after surgical debulking and chemotherapy with platinum-based agents.
Adenocarcinoma, Papillary↗
[A rare case of an adenomatoid mesothelioma of the fallopian tube combined with ovarian stromal hyperplasia and hyperthecosis, endometrial adenocarcinoma and endometriosis interna].
Adenomatoid mesothelioma is a rare benign tumor, most commonly located in the uterine corpus and fallopian tubes in the women during the reproductive years. It usually occurs occasionally and there are no specific symptoms. A case is presented of an adenomatoid tumor of the fallopian tube, associated with many other pathological findings of the genital tract. It is important to recognize the pseudoglandular pattern of this rare kind of benign tumor to avoid a mistaken diagnosis of adenocarcinoma or metastasis.
Adenocarcinoma↗
Bilateral papillary adenofibroma of the fallopian tube.
A unique case of bilateral papillary adenofibroma of the fallopian tube is reported. The seven-year disease-free follow-up after simple excision without salpingectomy further confirms the benign nature of this entity.
Adenofibroma↗
Fallopian tube patency using color Doppler.
OBJECTIVE: To evaluate a new test for tubal patency using color Doppler ultrasonography in infertile women. METHOD: Between October 1991 and March 1992 results of our new technique were compared with those of hysterosalpingography (HSG) and laparoscopy in 27 cases. The new technique of evaluating tubal patency using color Doppler has been described in detail. RESULT: There was 92.59% agreement, i.e. patency or occlusion of the fallopian tubes when the results of our test were compared with those of hysterosalpingography and laparoscopic chromopertubation. The HSG and laparoscopy findings were in 100% agreement. CONCLUSION: Color Doppler ultrasonography is now a very important investigation in the assessment of fallopian tube patency and compares favorably with the existing 'gold standards' namely HSG and laparoscopic chromopertubation.
Fallopian Tube Patency Tests↗
Terbutaline in diagnosis of interstitial fallopian tube obstruction.
Effectiveness of terbutaline, a potent uterine muscle relaxant, for differentiation of temporary and anatomic interstitial fallopian tube obstruction (IFTO) at hysterosalpingography (HSG) was explored. In 43 IFTO evaluated, HSG after terbutaline showed patency in only one of 16 tubes in which IFTO was caused by spasm or other temporary cause. We conclude that terbutaline is not helpful in differentiating temporary from anatomic tubal obstruction during HSG.
Fallopian Tube Diseases↗
Heterologous carcinosarcoma of the fallopian tube. A case report.
Carcinosarcomas occur infrequently in the female genital tract. They arise predominantly in the uterus and much less frequently in the vagina, cervix and ovary. They rarely occur in the fallopian tube; only 25 such cases have been reported in the literature to date. The rarity of carcinosarcoma of the fallopian tube prompted this case report.
Aged↗
Glassy cell carcinoma of the fallopian tube. A case report.
A 31-year-old woman, 10 weeks postpartum, presented with a right adnexal mass. The neoplasm was found to originate from the right fallopian tube and a right salpingoophorectomy was performed. Pathological examination found an adenosquamous carcinoma with features characteristic of a glassy cell carcinoma as described in the uterine cervix. The finding of this neoplasm in the fallopian tube suggests that it may be a tumor type common to the entire müllerian system.
Adenocarcinoma↗
Two modifiers of sperm transport within the fallopian tube of the rat.
In several mammals studied, ovulation appears to stimulate coordinated translocation of a few potential fertilizing spermatozoa to the ampulla from the caudal isthmus of the Fallopian tube. The present experiments demonstrate that, in the rat, this movement is regulated to a considerable degree within each duct by the ipsilateral ovary. Unilateral ovariectomy had no effect on ipsilateral sperm transport into the uterus, but this brought a unilateral quenching of sperm transport to the ampulla of the oviduct, from which spermatozoa were often totally or almost absent. This suppression was always complete on the ipsilateral side in unilaterally ovariectomized females anaesthetized with sodium pentobarbital soon after ovulation, and was evident bilaterally also at a highly significant level among intact females that were anaesthetized in this way. Unilateral ovariectomy and sodium barbital anaesthesia could provide experimental situations through which to decipher the mechanisms of normal sperm transport in the Fallopian tube.
Animals↗
Torsion of the normal fallopian tube in pregnancy.
Two cases of torsion of the normal fallopian tubes during the third trimester of pregnancy are presented. The etiology and clinical features of this complication are discussed. Although uncommon, it should be included in the differential diagnosis of abdominal pain in pregnancy.
Abdomen↗
Rabbit fallopian tube reanastomosis using a microvascular stapling device.
The 3M Precise Microvascular Anastomotic System (MAS), a microvascular stapling device, was compared with microsurgery for the reanastomosis of rabbit fallopian tubes. Differences in operative time, tubal patency, adhesion formation, and fertility rate were studied in 18 rabbits. Only 17% of tubes repaired by MAS were subsequently patent by chromopertubation, compared with 72% with microsurgery. Mean nidation indices were 0.05 for MAS and 0.22 for microsurgery. Sixty-one percent of adnexae repaired by MAS were adhesion stage I, whereas 83% of microsurgically repaired adnexae were stage I. Mean operative time was 28.2 min for MAS vs 21.6 min for microsurgery. Only the differences in patency rate and operative time were statistically significant, but the trends suggest that fallopian tube reanastomosis by MAS offers no advantage over conventional microsurgical technique.
Animals↗
Replacement, repair, and removal of fallopian tubes.
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Fallopian Tube Diseases↗
[Endometriosis of the Fallopian tubes].
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Endometriosis↗
Experimental nonsurgical female sterilization: transcervical implantation of microspindles in fallopian tubes.
PURPOSE: A nonsurgical method of female sterilization was investigated in rabbits. MATERIALS AND METHODS: A self-expanding microspindle (length 9-18 mm, diameter 1.5-2.0 mm) made from tubular metal mesh was implanted in a single fallopian tube of 12 rabbits via catheterization of a single uterus. The contralateral fallopian tube and uterus served as controls. Each rabbit was scheduled to undergo three cycles of breeding. Before delivery, absence of pregnancy on the side with the microspindle was verified with hysterography. RESULTS: Eight rabbits completed three cycles of breeding and pregnancy. Two rabbits had one pregnancy. Two rabbits did not conceive. Spindles were placed correctly in 11 rabbits. Successful contraception was achieved in nine rabbits, who had 25 gestations on the nonspindle side and no gestation on the spindle side. One rabbit, which received the shortest spindle, was bilaterally pregnant, indicating a failure of contraception on the spindle side. No spindles dislocated. Histologic study showed all spindles firmly embedded in the tubal wall without signs of inflammation. CONCLUSION: Microspindles of a certain minimum length have potential as a transcervically implantable, permanent intratubal contraceptive device.
Animals↗
Localization and role of endothelin-1 and endothelin receptors in the human Fallopian tube.
The present experiments were designed to investigate the localization and role of endothelin-1 (ET-1) and endothelin receptors (ET(A) and ET(B)) in human Fallopian tubes obtained from patients in the follicular phase. Immunohistochemical studies revealed the predominant localization of ET-1 and of ET(B) receptors in the tubal epithelium and also within the muscle layer to a lesser degree. ET(A) receptors were dominant within the muscle layer. Scatchard plot analysis of the [(125)I]ET-1 binding also revealed the localization of ET(A) and ET(B) receptors on the Fallopian tubal membrane. A dissociation equilibrium constant of 34.6 +/- 3.3 pmol/l and a maximum binding site concentration of 1137.0 +/- 239.1 fmol/mg protein were obtained from the Scatchard plot analysis. Treatment of Fallopian tubal strips with ET-1 produced a tonic contraction which was inhibited by an ET(A) antagonist but not by an ET(B) antagonist. However, the increase in frequency and decrease in amplitude of rhythmic contractions caused by ET-1 were modulated by the ET(B) antagonist but remained unaffected by the ET(A) antagonist. These results suggest that ET-1 modulates the motility of the Fallopian tube through excitation of ET(A) and/or ET(B) receptors and possibly plays some role in oocyte capture.
Adult↗