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[Results of treatment of acute cholecystitis following conservative therapy, interval operation and early operation].

The results achieved by conservative treatment interval operation and early operation in 981 patients suffering from acute cholecystitis were compared in a retrospective study by means of electronic data processing (EDP). There is no difference in length of operating time, intra- and postoperative complications and mortality rate between operation at an interval and early operation. By introducing the early operation the total mortality rate of all patients suffering from acute cholecystitis decreased from 7% to an average of 2.5%.

Acute Disease↗

[Evaluation of the effect of the work environment on the state of the oral cavity].

2439 men and employed in 4 industrial plants of Szczecin area had their masticatory system examined. Onto the cards prepared for electronic data processing the information has been written on: oral cavity caries (IMF), oral mucosa membrane, periodontium, parafunction and T.M.J. dysfunction. The main exposure factors of those plants have been determined, namely: welding gas, aromatic hydrocarbons, fluorine compounds, and copper dusts. The IMF values, oral hygiene, periodontal diseases as well as the TMJ-dysfunction in the test workers have been found to be approximately similar to the relevant values of other populations and to vary with sex, age or poor hygienic conditions. On the other hand, the prevalence of oral leukoplakia and parafunction seems to be dependent on the working environment.

Adult↗

Digital pulse plethysmography--a tool for investigating vasoactive substances.

Plethysmographic investigations have been in use for at least a hundred years for the measurement of pharmacological actions in humans. Finger plethysmography was used particularly in the investigation of the vasodilating effect of organic nitrates. It has also proved valuable in determining the relative bioavailability of representatives of this class of drugs. This paper deals with personal experience in the use of this method for the investigation of older and newer organic nitrates. The apparatus that was developed to enable electronic data processing of the plethysmographic signals is described. The effects of other pharmacological interventions on finger volume pulse are also discussed, and the finger plethysmographic investigation of vasodilating substances that belong to classes of drugs other than organic nitrates is presented. The possibilities and limits of the method are discussed.

Carbazoles↗

[Late sequels EPH gestosis (author's transl)].

The courses of the following three groups of pregnancies were studied in the context of 146 women, with twelve years, on average, having elapsed from their first pregnancies: 1. Normal pregnancies without EPH gestosis (58 cases); 2. Pregnancies with EPH gestosis (58 cases); 3. Pregnancies with eclampsia (30 cases). - All clinical findings and statistical calculations were evaluated by means of electronic data processing. - Average systolic and diastolic blood pressures were established in follow-up checks, usually twelve years from pregnancy. They were normal, following normal pregnancies. Statistically secured blood pressures measured from patients with gestosis or eclampsia during their first pregnancy were higher than those recorded from patients in a control group, but pathological values were established in but few cases. - The following, more specialised checks proved or particular importance for an evaluation of EPH gestosis and its effects on liver function following pregnancy: serum electrophoresis, thymol test, SGOT, SGPT, direct and indirect bilirubin, blood and urinary sugar, serum cholesterol, and total fats. - The above results are likely to show that EPH gestosis and its effects are relatively well tolerated by the liver. However, discrete disorders characterised by dysproteinaemia without cellular decay and icterus may occur in certain instances.

Cardiovascular Diseases↗