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At least 721 records · Page 40Linked to original sources
PubMed1990

Morphological aspects of the synovial membrane and the femoral epiphyseal nucleus in anemia induced experimentally (note 1).

The authors describe the macroscopic and ultra-structural changes in the synovial membrane and the growth nucleus consequent to anemia induced experimentally. In the anatomical region studied an early and a late response to the transitory anoxia is observed. The former is represented by the accentuation of the macrophagic activity of the A synoviocytes and by pictures of trabecular fragmentation. The latter is represented by hyperplasia of the synovial membrane, a reduction in the thickness of the joint cartilage, and by early and patchy calcification of the epiphyseal disc.

Anemia↗
PubMed1989

[The clinical x-ray picture and treatment of the hemimelic form of epiphyseal dysplasia].

The authors have studied the course and the efficacy of the surgical treatment of the hemimelic form of epiphyseal dysplasia in 15 children. Three roentgenologic types of epiphysis lesions have been distinguished. It has been determined that the pathologic changes are mainly localized in the posterior medial departments. In multiple severe lesions hyperfunction of the growth areas followed by their early asymmetric synostosis with the development of secondary deformations and focal disturbances in the ossification of the metaphyses have been observed. The necessity of early surgical treatment allowing to prevent the development of the pathologic changes in the growth areas and deforming arthrosis has been substantiated.

Child↗
PubMed1988

Humeral trochlear hypoplasia secondary to epiphyseal injury as a cause of ulnar nerve palsy.

Humeral trochlear hypoplasia (HTH) is a rare condition that occasionally results in ulnar nerve palsy. A 41-year-old man developed HTH secondary to an epiphyseal injury of the trochlea incurred 33 years earlier. This may be the first report of a case of HTH caused by injury. The ulnar nerve appeared compressed by the malposition of the HTH against the medial head of the triceps brachii when the joint was flexed. The close proximity of the olecranon to the HTH also allowed the triceps brachii muscle to compress the nerve by displacing medially and overriding the bone. The condition was resolved surgically and the patient returned to his former occupation as a coal miner.

Adult↗
PubMed1989

Epiphyseal distraction. Chondrodiatasis.

Chondrodiatasis is a limb-lengthening technique involving slow, controlled, symmetric epiphyseal distraction. The clinical and histological differences between this technique and distraction epiphysiolysis are described. Results are given for the elongation of 170 bone segments in 75 children (41 with limb-length discrepancies and 34 with achondroplasia). All patients were operated upon while the growth plate was still open with maximum bone maturation corresponding to Risser 2.

Achondroplasia↗
PubMed1989

Epiphyseal distraction. Hemichondrodiatasis.

Hemichondrodiatasis is a technique of closed, gradual, asymmetric distraction of the growth plate to correct angular deformities in growing children. This report describes the technique and the results achieved in 35 operated lower extremity segments, 14 involving the femur and 21 involving the tibia. The best results were achieved in posttraumatic deformities when the bone bridge occupied less than 20%-30% of the epiphyseal plate. The procedure is best performed toward the end of growth, or earlier if a progressive deformity exceeds 15 degrees - 20 degrees.

Adolescent↗
PubMed1988

The presence of a myeloid cell population showing strong reactivity with monoclonal antibody directed to difucosyl type 2 chain in epiphyseal bone marrow adjacent to joints affected with rheumatoid arthritis (RA) and its absence in the corresponding normal and non-RA bone marrow.

The presence of a specific type of cell, highly expressing difucosyl type 2 chain (dimeric Lex; FH-4 antigen), was found in the epiphyseal bone marrow cells of affected joints from patients with active severe rheumatoid arthritis (RA). The antigen was defined by monoclonal antibody FH-4 which was previously found to be directed to the oncofetal marker. The FH-4(+) cell population was identified as myeloid cell lineage with usual morphology specifically found in bone marrow of patients with severe RA, but is virtually absent in the same cell fraction of patients with osteoarthritis, infectious arthritis, and from normal adult subjects.

Adult↗
PubMed1988

[Spontaneous epiphyseal separation in children with spina bifida. Apropos of a series of 12 cases].

Unknown complication but nevertheless frequent, the spontaneous slipped epiphyseal injury in child with spina bifida states the problem for its diagnosis and its treatment. The authors give their experience about 12 cases in 10 children, insisting on the problem of the pseudo-infected and the pseudo-tumoral cases with an early diagnosis. A review of the literature is made about this subject. The treatment is generally orthopaedic excepted at the hip where it is surgical. A physiopathogenic study is made; explaining the mechanism, the frequency of this pathology and its complications.

Bone Neoplasms↗
PubMedDate not supplied

Epiphyseal separation in scurvy.

The case of a 10-month-old boy with scurvy and epiphyseal displacement of both the distal femur and the right proximal tibia is presented. He was treated without reduction of the displacement.

Bed Rest↗
PubMed1988

Tibial lengthening by epiphyseal distraction.

Tibial lengthening by slow distraction of the distal epiphysis using the dynamic axial fixator was performed in 3 patients near to skeletal maturity, in 2 patients with congenital origin and in one with achondroplasia. The obtained lengths were 4.4 cm (17% of the tibial length), 3.7 cm (12%) and 3.6 cm (19%). There were no serious complications. Bone formation at the site of distraction was thought to be periosteal in origin when assessed using X-rays and computerized tomography. There was no radiological evidence that bone at the distracted sites was formed by an apposition from the metaphyseal side which is expected in cases of stimulation of endochondral ossification in the growth plate. There was no further measurable growth at the distracted growth plates after lengthening. This method is useful for limb lengthening near the time of epiphyseal closure.

Adolescent↗
PubMed1988

Gene expression in mineralizing chick epiphyseal cartilage.

To map transcriptional events associated with mineralization in developing long bones, we have established protocols for preparing RNA from regions of chick epiphyseal cartilage. Using these RNA preparations, we have probed for appearance of mRNA coding for type I, II, and X collagen, as well as osteonectin and calmodulin. Type II collagen mRNA was found in proliferating cartilage and, in lower amounts, in hypertrophic/calcifying cartilage. Type X mRNA was absent from proliferating cartilage and present in hypertrophic/calcifying cartilage at steady state levels slightly lower than that of type II mRNA. Type I mRNA was the major collagen mRNA species in endochondral bone; however, significant amounts of type X mRNA were also found. Examination of type X/type II ratios suggest that the cells producing type X mRNA in bone are different from those in the hypertrophic/calcifying cartilage region. Osteonectin mRNA was present in endochondral bone; however, significant amounts were also detected in precalcified cartilage. Indeed, the level of osteonectin mRNA was significantly higher in the resting/proliferating region than in the hypertrophic/calcifying region of the cartilage. No correlation was observed between calmodulin mRNA and the development of mineralization; levels of this message were slightly lower in endochondral bone, embryonic sterna, and calvaria than they were in chick liver and considerably lower than the calmodulin mRNA levels in chick brain.

Animals↗
PubMed1988

An epiphyseal giant cell tumor associated with early Paget's disease. A case report.

An epiphyseal giant cell tumor occurred in a 50-year-old woman in the absence of roentgenographic signs of Paget's disease adjacent to the tumor area. Only one case with similar features has been previously reported. Treatment increased bone remodeling changes in the whole femur. Two years later the high bone turnover of the femur was arrested. This case suggests that a giant cell tumor of the epiphysis developed in an early phase of Paget's disease.

Bone Neoplasms↗
PubMedDate not supplied

Primary subacute epiphyseal osteomyelitis: a report of three cases.

Three patients with primary subacute epiphyseal osteomyelitis are reviewed. All had a history of minor trauma and complained of pain and limp; none was systemically ill. Plain radiographs demonstrated a well-defined lytic lesion in the epiphysis. One case occurred in the distal tibial epiphysis from which pneumococci were isolated; this appears not to have been described previously. Patients were treated with flucloxacillin and two without operative intervention; all recovered completely. Follow-up radiographs at 2-5 years demonstrated healing of the lesions with no evidence of damage to the epiphysis or the joint. There have been 10 previously reported cases in the literature, all treated by antibiotics and curettage. Based on this experience we believe that administration of appropriate antibiotics and immobilisation of the affected limb are sufficient treatment for some children presenting with this condition.

Acute Disease↗
PubMed1985

[Treatment and results following para-articular epiphyseal injuries of the knee during the growth period].

A total of 23 children aged 3 to 18 years, underwent treatment in a period of 14 years. They were followed-up from 1 to 12 years later. The follow-up examinations confirmed that the treatment has to consider the kind of epiphyseal injury, its localisation and the patient's age in order to avoid prearthrotic deformity. Thus, conservative and operative treatment have their exact indication.

Adolescent↗
PubMed1973

Collagen-proteoglycan relationships in epiphyseal cartilage.

Columnar and hypertrophic zones of calf scapular cartilage were studied before and after extraction with 3 M guanidinium chloride (GuCl) and digestion with enzymes which degrade various components of the extracellular matrix. Morphologic and chemical analysis suggests that there are at least two anatomic pools of proteoglycan in this tissue. One, which resides between collagen fibrils, is extractable with GuCl. Another appears attached to collagen by strong bonds and is apparently not extractable with GuCl. This type of collagen-proteoglycan relationship is possibly restricted to epiphyseal cartilage. The morphology of the lacuna is different in the columnar and hypertrophic zones. Proteoglycans in the distal hypertrophic zone are less resistant to GuCl extraction.

Animals↗
PubMedDate not supplied

Epiphyseal osteochondroma of the anterior cruciate ligament.

An 8-year-old Black boy complained of pain, swelling, and a decreased range of motion in the knee. One arthrotomy operation was reported to show a normal knee joint. Six months later, a second arthrotomy demonstrated an osteochondroma growing from the epiphysis into the anterior cruciate ligament. Epiphyseal osteochondroma should be added to the working differential diagnosis on children with effusion and decrease of knee motion.

Bone Neoplasms↗
PubMed1979

Fractures of the tibia through the proximal tibial epiphyseal cartilage.

Thirty-nine fractures of the tibia involving the proximal tibial epiphyseal cartilage were treated at the Campbell Clinic over a twenty-five-year period. Stress roentgenograms were essential in making the diagnosis in three patients. Two patients had disruption of the popliteal artery, and both had posterior displacement of the tibial shaft. The other immediate complications that we encountered were anterior compartment syndrome, peroneal-nerve palsy, and associated ligamentous and meniscal injuries. Of twenty-eight fractures (twenty seven patients) with an average follow-up of 7.1 years, there were satisfactory results in twenty-four. Unsatisfactory results (four fractures) were due to chronic neurovascular insufficiency, growth disturbance, or traumatic arthritis.

Adolescent↗
PubMed1984

[Epiphyseal fixation with an external fixator. Biomechanical and clinical study].

Fifty one fractures of an epiphysis were treated by fixation using a new external fixator. The stability of the fixation was compared with that obtained by other types of fixator. The basis of the technique was the insertion of five pins into the epiphysis and of a series of pins in the diaphysis. Fixation between the epiphyseal and diaphyseal pins was achieved by three bars. The results obtained in 38 cases, half of them being at the proximal end of the tibia were analysed and were found to be encouraging. Only three had to be grafted secondarily. There was a low number of mal-unions. The main advantage of this method was to allow early mobilisation of the joint. The risk of sepsis did not give rise to concern provided that the rods do not cross the joint.

Biomechanical Phenomena↗