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PubMed2005

[Antiemetic agents are contraindicated in children with acute gastroenteritis].

Elsewhere in this issue, De Moor et al. describe acute urinary retention as a side effect of antiemetic agents in children. This confirms once again that in the treatment of children with gastroenteritis there is no place for any medication other than oral rehydration fluids. After all, the efficacy of antiemetics for this indication has not been proven, whilst there is a real chance of side effects such as dystonia and now also urinary retention.

Acute Disease↗
PubMedDate not supplied

[Is there a role for calcium antagonists when beta-adrenergic blockade therapy is contraindicated in post-myocardial infarction?].

The purpose of this paper is to examine the eventual benefits of treatment with calcium channel blockers in post-myocardial infarction, through an overview of main placebo-controlled trials that have been conducted to test this therapeutic in acute coronary syndromes. It appears obvious that the vast majority of these trials was conducted in the pre-reperfusion era and failed to demonstrate a reduction in mortality. To conclude, the superiority of a therapy with calcium antagonists over a placebo in the management of post-myocardial infarction remains unknown. In contrast, adverse effects associated with the prescription of calcium antagonists are well known.

Adrenergic beta-Antagonists↗