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Some algebraic properties of crystallographic sublattices.

In this article, a number of the results relevant to the concept of sublattices of a basic crystallographic lattice are reviewed, emphasizing particularly previously unpublished work on the algebraic aspects. A three-dimensional geometric lattice L can be considered as an infinite Abelian group under addition. A sublattice S of L, which is also three-dimensional, is a subgroup of L such that the finite quotient group, G approximately equals L/S, is an Abelian group of order the index of S in L. The sublattice itself in its standard form is represented by an upper triangular matrix. The index of the sublattice is given by the determinant of this matrix. It is first noted that a sublattice described by an arbitrary basis set in L may be converted to this standard form. Next the sublattice is expressed as the intersection of a set of sublattices of individual index a power of a distinct prime, i.e. S(n = p(a)(1)p(b)(2)...) = S(1)(p(a)(1)[cap]S(2)(p(b)(2)...[cap]... = [bigcap](i)S(i)(p(alpha(i)), where p(1), p(2) etc. are prime numbers and n = Pi(i)p(alpha)(i) is the Euclidean factorization of n. This decomposition is important because it corresponds to the Sylow decomposition of the corresponding quotient group G approximately equals (i)[sign: see text] A(p)(i). It is also useful to be able to carry out two commutative binary operations on sublattices of L; these are to find their common sublattice of lowest index in L, which is their intersection S(cap) = S(a)(m)[cap]S(b)(n) and their common superlattice of highest index in L, given by S(< >) = , where < > indicates the span of the sublattices.

Journal Article↗

Stability analysis and design of T-S fuzzy control system with simplified linear rule consequent.

Stability and design issues of simple T-S fuzzy control system with simplified linear rule consequent (TSS) are investigated. A systematic approach to find a common matrix P for TSS fuzzy system is presented, where system matrix Ai is decomposed into proportional part Ai and the remainder delta Ai. Hence an iterative approach to find a common matrix P for pairwise commutative Ai's can be used. The stability of the global system is guaranteed if delta Ai satisfies certain conditions. Qualitative instructions for TSS control system design are summarized. A physical example is given to illustrate the issues discussed throughout the paper.

Journal Article↗

Geometry of Dempster's rule of combination.

In this paper, we analyze Shafer's belief functions (BFs) as geometric entities, focusing in particular on the geometric behavior of Dempster's rule of combination in the belief space, i.e., the set Stheta of all the admissible BFs defined over a given finite domain theta. The study of the orthogonal sums of affine subspaces allows us to unveil a convex decomposition of Dempster's rule of combination in terms of Bayes' rule of conditioning and prove that under specific conditions orthogonal sum and affine closure commute. A direct consequence of these results is the simplicial shape of the conditional subspaces , i.e., the sets of all the possible combinations of a given BF s. We show how Dempster's rule exhibits a rather elegant behavior when applied to BFs assigning the same mass to a fixed subset (constant mass loci). The resulting affine spaces have a common intersection that is characteristic of the conditional subspace, called focus. The affine geometry of these foci eventually suggests an interesting geometric construction of the orthogonal sum of two BFs.

Journal Article↗

Profiles of refugee and non-refugee Palestinians from the West Bank and Gaza.

Relying on demographic and labor surveys which the Palestinian Central Bureau of Statistics collected in 1995, this article investigates the profile of West Bank and Gaza refugees. Refugees are better educated and have higher fertility than non-refugee Palestinians, but the difference is small. However, they have a significantly lower participation rate, a higher unemployment rate and a higher incidence of arrests and work stoppage than the corresponding rates among non-refugee Palestinians. A smaller proportion of Palestinians commute to work into the Israeli labor market and refugees earn lower wages than nonrefugees. Returns to investment in education are small for both groups. High fertility among refugees imposes a future challenge for policy makers in terms of resources required for the provision of appropriate education and health facilities. Employing future labor market entrants is another serious policy challenge.

Asia↗

Extended workshifts and excessive fatigue.

Studies of overtime have pointed to fatigue as a potential factor producing, for example, a three-fold increase in accident rate after 16 h of work, increases in back injuries, hospital outbreaks of bacterial infection, or nuclear-power plant safety compromises. Fatigue has been measured more directly in studies of scheduled long workshifts, where performance decrements in both work-related tasks and laboratory-type behavioural tests have been observed, and significant loss of sleep and increases in subjective sleepiness have been reported. Analyses of accidents or injuries during scheduled extended workshifts, however, have produced equivocal results. Factors which could compound the fatiguing effects of extended workshifts, such as workload, noise, chemical exposure, or duties and responsibilities outside of the workplace, rarely have been studied systematically. It is concluded that extended workshift schedules should be instituted cautiously and evaluated carefully, with appropriate attention given to staffing levels, workload, job rotation, environmental exposures, emergency contingencies, rest breaks, commuting time, and social or domestic responsibilities.

Journal Article↗

Impaired alertness and performance driving home from the night shift: a driving simulator study.

Driving in the early morning is associated with increased accident risk affecting not only professional drivers but also those who commute to work. The present study used a driving simulator to investigate the effects of driving home from a night shift. Ten shift workers participated after a normal night shift and after a normal night sleep. The results showed that driving home from the night shift was associated with an increased number of incidents (two wheels outside the lane marking, from 2.4 to 7.6 times), decreased time to first accident, increased lateral deviation (from 18 to 43 cm), increased eye closure duration (0.102 to 0.143 s), and increased subjective sleepiness. The results indicate severe postnight shift effects on sleepiness and driving performance.

Accidents, Traffic↗

An evaluation of the effectiveness of audio cassettes for CME.

Medical teachers and practising doctors were surveyed by questionnaire and given pre- and post-tests to determine the efficiency and effectiveness of Practical Reviews in Cancer Management, a cassette tape programme of continuing medical education (CME). Doctors indicated a high degree of satisfaction with this approach; in particular the idea of keeping abreast of the current literature while commuting in their cars was appealing. The programme's effectiveness was measured by pre- and post-tests, and the data were analysed by the non-directional t-test for dependent groups. These tests indicated a significant (P less than 0.001) increase in knowledge from the pre- to post-tests.

Alabama↗

In vitro-generated viral double-stranded RNA in contrast to polyinosinic:polycytidylic acid induces interferon-alpha in human plasmacytoid dendritic cells.

Double-stranded RNA (dsRNA) arises in the cytoplasm during viral replication and was shown to participate in the interferon (IFN)-alpha induction process. Besides the intracellular recognition, released dsRNA from dying, infected cells can function as a pathogen-associated molecular pattern (PAMP) for the innate immune system. In the present study, in vitro-generated dsRNA fragments of genomic sequences of Newcastle disease virus were used to induce IFN-alpha release in human peripheral blood mononuclear cells (PBMC), in immature myeloid dendritic cells (mDC) and in immature plasmacytoid DC (pDC). The extracellular administration of dsRNA fragments but not the application of the corresponding single-stranded RNA (ssRNA) strands led to an IFN-alpha production in PBMC. The synthetic dsRNA analogue polyinosinic acid : polycytidylic acid [Poly(I : C)] could only stimulate IFN-alpha production in enriched mDC but not in pDC. In contrast, dsRNA fragments induced IFN-alpha only in pDC. Complexation of dsRNA fragments with transfection reagents increased the efficiency of IFN-alpha induction and commuted ssRNA molecules into IFN-alpha inducers. However, stimulation of in vitro-generated murine Toll-like receptor 7 (TLR7) knockout DC and human TLR-transfected HEK293 cells with dsRNA fragments gave no evidences for the involvement of pDC-specific TLR7 or TLR9 in the observed IFN-alpha induction.

Animals↗

'Take the stairs instead of the escalator': effect of environmental prompts on community stair use and implications for a national 'Small Steps' campaign.

The US government initiated a national health campaign targeting 100 'small step' lifestyle changes to combat obesity. Small Step #67 advocates stair instead of escalator usage in public settings. The aim of this study is to evaluate the effects of motivational signs prompting stair use over escalator use on pedestrians' stair usage in commuter settings. Eight studies, testing the effects of motivational prompts on stair vs. escalator usage in public settings, were reviewed. Participant and study attributes were descriptively coded. Effect size was calculated as the change in percent units of stair users during the intervention phases vs. the baseline phase. The average study included approximately 45,000 observations that were recorded across an average of 15 weeks of intervention. The mean +/- SD change in percent units of stair users was 2.8% +/- 2.4% (P < 0.001), and effects were twice as large in females (4.8%) as in males (2.4%). The number of stairs/building, baseline stair use, and total intervention weeks predicted change in stair use, although the effects were clinically miniscule. In a hypothetical city intervention, we projected that a 2.8% increase in stair usage would result in a weight loss and/or weight gain prevention of 300 g/person/year among new stair users. In sum, point-of-decision motivational signs may help communities attain Small Step #67. However, the singular impact of this community intervention on correcting energy imbalance may be minimal, having slight impact itself on reducing the national obesity prevalence.

Elevators and Escalators↗

Left and right pump output control in one-piece electromechanical total artificial heart.

Left master alternate (LMA) ejection control based on the left pump fill method was implemented for a one-piece electromechanical total artificial heart (TAH). The TAH consists of left and right pusher-plate-type blood pumps sandwiching a compact electromechanical actuator comprising a direct current (DC) brushless motor and a planetary roller screw. The motor rotation is controlled on the basis of the roller-screw position as detected by a Hall effect sensor and a commutation pulse counting method. Since the pusher-plate shaft and roller screw are decoupled during filling, both pumps fill passively with the right and left atrial pressure. To obtain response to the right atrial pressure change in the LMA mode, the left fill trigger level as detected by a Hall effect position sensor is adjusted to operate the pump at a higher rate and to drive the right pump at 85-90% of the full stroke level. The in vitro evaluation demonstrated that this method can respond to right atrial pressure changes provided that the right pump is operated at less than the full stroke level. When the preload is high and the right pump goes into full stroke operation, the left eject level can be decreased to run the pump at a higher rate and to transfer more blood from the right to the left. In the in vivo evaluation, which lasted 1 week in a 95 kg calf, the left and right atrial pressures were kept within physiological ranges.(ABSTRACT TRUNCATED AT 250 WORDS)

Animals↗

Totally implantable total artificial heart and ventricular assist device with multipurpose miniature electromechanical energy system.

A multipurpose miniature electromechanical energy system has been developed to yield a compact, efficient, durable, and biocompatible total artificial heart (TAH) and ventricular assist device (VAD). Associated controller-driver electronics were recently miniaturized and converted into hybrid circuits. The hybrid controller consists of a microprocessor and controller, motor driver, Hall sensor, and commutation circuit hybrids. The sizing study demonstrated that all these components can be incorporated in the pumping unit of the TAH and VAD, particularly in the centerpiece of the TAH and the motor housing of the VAD. Both TAH and VAD pumping units will start when their power line is connected to either the internal power pack or the external battery unit. As a redundant driving and diagnostic port, an emergency port was newly added and will be placed in subcutaneous location. In case of system failure, the skin will be cut down, and an external motor drive or a pneumatic driver will be connected to this port to run the TAH. This will minimize the circulatory arrest time. Overall efficiency of the TAH without the transcutaneous energy transmission system was 14-18% to deliver pump outputs of 4-9 L/min against the right and left afterload pressures of 25 and 100 mm Hg. The internal power requirement ranged from 6 to 13 W. The rechargeable batteries such as NiCd or NiMH with 1 AH capacity can run the TAH for 30-45 min. The external power requirement, when TETS efficiency of 75% was assumed, ranged from 8 to 18 W. The accelerated endurance test in the 42 degrees C saline bath demonstrated stable performance over 4 months. Long-term endurance and chronic animal studies will continue toward a system with 5 years durability by the year 2000.

Animals↗

The implantable fuzzy controlled Helmholtz-left ventricular assist device: first in vitro testing.

To perform first experimental tests for validation of a new left ventricular assist device (LVAD) with a high efficiency energy converter, a new pump design and a novel type of perfusion control, a functional labtype, were manufactured. With a stroke volume of 65 ml, a total pump housing volume of 450 ml (including valves and connectors), and a weight of 430 g, it is one of the smallest and lightest implantable pulsatile electromechanical LVADs. Pulsatile operation is generated by a special reduction and displacement gear which transforms a uniform rotational movement of a sensorless, electronically commutated DC motor into a translatory pusher plate movement. A prolonged duration for filling (60% of the cycle time) supports full-empty pumping and consequently a high overall pump efficiency. Active adaptation of output flow to organ perfusion demand is achieved by changing the rotational speed of the motor by means of a sensorless fuzzy controller, which detects preload and afterload induced effects at the motor current input. First in vitro test results obtained within a circulatory mock loop that simulates physiological preloads and afterloads are presented. They comprise preload sensitivity and the function of the novel perfusion controller as well as preload and afterload related flow data. The results prove the feasability of the energy conversion with the novel gear and control concept for an implantable electromechanical pulsatile LVAD.

Animals↗

Impeller behavior and displacement of the VentrAssist implantable rotary blood pump.

The VentrAssist implantable rotary blood pump, intended for long-term ventricular assist, is under development and is currently being tested for its rotor-dynamic stability. The pump is of the centrifugal type and consists of a shaftless impeller, also acting as the rotor of the brushless DC motor. The impeller remains passively suspended in the pump cavity by hydrodynamic forces, resulting from the small clearances between the impeller outside surfaces and the pump cavity. In the older version of the pump tested, these small clearances range from approximately 50 microm to 230 microm; the displacement of the impeller relative to the pump cavity is unknown in use. This article presents two experiments: the first measured displacement of the impeller using eddy-current proximity sensors and laser proximity sensors. The second experiment used Hall-effect proximity sensors to measure the displacement of the impeller relative to the pump cavity. All transducers were calibrated prior to commencement of the experiments. Voltage output from the transducers was converted into impeller movement in five degrees of freedom (x, y, z, theta(x), and theta(y)). The sixth degree of freedom, the rotation about the impeller axis (theta(z)), was determined by the commutation performed by the motor controller. The impeller displacement was found to be within the acceptable range of 8 micro m to 222 microm, avoiding blood damage and contact between the impeller and cavity walls. Thus the impeller was hydrodynamically suspended within the pump cavity and results were typical of centrifugal pump behavior. This research will be the basis for further investigation into the stiffness and damping coefficient of the pump's hydrodynamic bearing.

Equipment Design↗

Comparison between participants and non-participants in a dental health survey in northern Norway.

The present study focused on possible differences with regard to sex, age, family income and dental status between those who did and those who did not attend a dental health survey. In a village in Northern Norway, all inhabitants aged 20-69 years (180 men and 178 women) were invited by mail to participate in a dental health survey. Two reminders were sent to non-respondents. Eighty-three percent of the target population attended for examination and interviews, and 94% responded to a follow-up questionnaire. Of all non-participants, men, and particularly young men, were overrepresented. Middle-aged people were more likely to participate than were persons under 30 and over 50 years of age. Furthermore, people belonging to the upper income groups seemed to be more willing to participate than those at lower income levels. Apparently, inconvenient working hours and long commuting distances had affected the participation. In addition, it seemed likely that anxiety and local factors had some influence.

Adult↗

Intensity of physical activity and respiratory function in subjects with and without bronchial asthma.

The aim of this study was to assess the intensity of physical activity of asthmatic adults in Finland and the associations between the intensity of physical activity and respiratory function in asthmatic and nonasthmatic persons. The study population (n=8000) was drawn from the population register to represent the Finnish population aged 30 years or over. Adequate information was available from 7193 subjects (89.9% of the sample). Physical activity at work, at leisure and during commuting was recorded with a standard questionnaire. The responses to the questionnaire were expressed as MET values. Asthma was defined on the basis of self-reports of chronic diseases previously diagnosed by a physician. The spirometric values (VC, FVC, FEV1, FEV%, and PEF) were negatively correlated with age. The results showed clear and significant associations between spirometric values and intensities of physical activity at work and during leisure time in asthmatic men. Although healthier subjects may select more physically demanding activities, it is an equally possible hypothesis that physical activity may improve respiratory function in subjects with and without bronchial asthma.

Adult↗

An analysis of Medicare's Incentive Payment program for physicians in health professional shortage areas.

CONTEXT: Medicare's Incentive Payment (MIP) program provides a 10% bonus payment to providers who treat Medicare patients in rural and urban areas where there is a shortage of generalist physicians. PURPOSE: To examine the experience of Alaska, Idaho, North Carolina, South Carolina, and Washington with the MIP program. We determined the program's utilization and which types of physicians received payments. METHODS: Retrospective cohort design, utilizing complete 1998 Medicare Part B data. Physician specialty was determined through American Medical Association data. Rural status was determined by linking the physician business ZIP code to its Rural-Urban Commuting Area code (RUCA). FINDINGS: There were 2,220,275 patients and 39,749 providers in the cohort, including 9,769 (24.6%) generalists, 21,331 (53.7%) specialists, and 8,649 (21.8%) nonphysician providers. Over $4 million in bonus payments (median payment = $173) were made to providers in HPSAs. Specialists and urban providers received 58% and 14% of the bonus reimbursements, respectively. Two million dollars in payments were not distributed because the providers did not claim them. Over $2.8 million in bonus claims were distributed to providers who likely did not work in approved HPSA sites. CONCLUSIONS: The MIP bonus payments given to providers are small. Many providers who should have claimed the bonus did not, and many providers who likely did not qualify for the bonus claimed and received it. Consideration should be given to focusing and enlarging the bonus payments to specific providers, rather than rewarding all providers equally. Policy makers should also consider a system that prospectively determines provider eligibility.

Alaska↗

Urban/rural differences in decision making and the use of advance directives among nursing home residents at admission.

CONTEXT: Advance directives promote patient autonomy and encourage greater awareness of final care options while reducing physician and family uncertainty regarding patient preferences. PURPOSE: To investigate differences in decision making authority and the use of advance directives among nursing home residents admitted from urban and rural areas. METHODS: A total of 551,208 admission assessments in the Minimum Data Set were analyzed for all residents admitted to a nursing facility in 2001. Using the Rural Urban Commuting Areas (RUCA) methodology and ZIP code of primary residence before admission, these residents were classified into 4 urban/rural areas. FINDINGS: Residents from rural areas were significantly more likely to have executed a durable power of attorney for health care or for financial decisions than residents admitted from the other areas, with the largest differences observed between residents admitted from urban and rural areas. Almost 6 residents in 10 from urban areas had no advance directives in place at admission compared with only 4 residents in 10 admitted from rural areas. CONCLUSIONS: Health providers and social workers in both rural and urban areas should advise patients about the value of advance directives.

Advance Directives↗

High school census tract information predicts practice in rural and minority communities.

PURPOSE: Identify census-derived characteristics of residency graduates' high school communities that predict practice in rural, medically underserved, and high minority-population settings. METHODS: Cohort study of 214 graduates of the University of California, San Francisco-Fresno Family Practice Residency Program (UCSF-Fresno) from its establishment in 1970 through 2000. Rural-urban commuting area code; education, racial, and ethnic distribution; median income; population; and federal designation as a medically underserved area were collected for census tracts of each graduate's (1) high school address and (2) practice location. FINDINGS: Twenty-one percent of graduates practice in rural areas, 28% practice in areas with high proportions of minority population (high minority areas), and 35% practice in federally designated medically underserved areas. Graduation from high school in a rural census tract was associated with rural practice (P < .01), Of those practicing in a rural site, 32% graduated from a rural high school, as compared with 11% of nonrural practitioners. Graduation from high school in a census tract with a higher proportion of minorities was associated with practice in a proportionally high minority community (P = .01). For those practicing in a high-minority setting, the median minority percentage of the high school census tract was 31%, compared with 16% for people not practicing in a high minority area. No characteristics of the high school census tract were predictive of practice in a medically underserved area. CONCLUSION: Census data from the residency graduate's high school predicted rural practice and practice in a proportionally high minority community, but not in a federally designated medically underserved area.

Adolescent↗