[Infectious disease epidemiology in the elderly].
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Age Distribution↗
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Results for “COMMUNICABLE DISEASE CONTROL”
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[The resolved and unresolved problems of the infectious disease service in the Russian Federation].
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Child↗
SARS: responding to an unknown virus.
The severe acute respiratory syndrome (SARS) is an emerging infection caused by a novel coronavirus which first appeared in southern China at the end of 2002. In early 2003, through a single incident, it spread to Hong Kong, Singapore, Canada and Vietnam. For busy clinicians in large public hospitals, the response to the virus was initially based on ensuring a high level of protection for staff. However, as the epidemic progressed and more information became available about the virus, procedures were rationalized and the virus is currently under control worldwide. There are, however, numerous unanswered questions concerning super-spreading events, the modes of transmission of the virus and, perhaps most importantly, the rapid detection of the virus early in the course of disease. These issues need to be addressed in case the virus becomes more widespread in the near future.
Communicable Disease Control↗
Importance of National Institute of Infectious Diseases and Institutes of Public Health on control of infectious diseases in the new century.
As the incidence of infectious diseases has recently decreased, we are faced with new problems, such as emerging and re-emerging infectious diseases, food poisoning, zoonosis, and bio-terrorism. In light of these new conditions, the National Institute of Infectious Diseases, the Local Institutes of Public Health, public health offices, and other medical organization must maintain close relationship in order to protect the health and safety of the citizens.
Communicable Disease Control↗
alpha+-Thalassemia protects children against disease caused by other infections as well as malaria.
In the South West Pacific region, the striking geographical correlation between the frequency of alpha+-thalassemia and the endemicity of Plasmodium falciparum suggests that this hemoglobinopathy provides a selective advantage against malaria. In Vanuatu, paradoxically, alpha+-thalassemia increases the incidence of contracting mild malaria in the first 2 years of life, but severe disease was too uncommon to assess adequately. Therefore, we undertook a prospective case-control study of children with severe malaria on the north coast of Papua New Guinea, where malaria transmission is intense and alpha+-thalassemia affects more than 90% of the population. Compared with normal children, the risk of having severe malaria was 0.40 (95% confidence interval 0.22-0.74) in alpha+-thalassemia homozygotes and 0.66 (0.37-1.20) in heterozygotes. Unexpectedly, the risk of hospital admission with infections other than malaria also was reduced to a similar degree in homozygous (0. 36; 95% confidence interval 0.22-0.60) and heterozygous (0.63; 0. 38-1.07) children. This clinical study demonstrates that a malaria resistance gene protects against disease caused by infections other than malaria. The mechanism of the remarkable protective effect of alpha+-thalassemia against severe childhood disease remains unclear but must encompass the clear interaction between this hemoglobinopathy and both malarial and nonmalarial infections.
Child↗
Biosecurity for reproductive diseases.
Application of rational principles of risk management in designing an effective biosecurity plan for reproductive diseases can be an important part of a profitable operation. Knowledge of the disease status of the particular herd, the effective strategies for disease exclusion including test performance and reservoirs is necessary. Vaccination can be an effective part of a biosecurity program by increasing herd immunity and decreasing the impact of an outbreak, but by itself will not prevent infections and losses. A more comprehensive approach to disease control is needed. Development and implementation of a biosecurity program is an individualized effort undertaken for a particular operation. Knowledge of the disease status of the herd for each agent of concern and prioritization of the diseases most important in the herd is necessary. The biosecurity plan is then specific for the herd and the particular agent(s) of concern. Practitioners can apply knowledge of the epidemiology and ecology of disease agents to identify and implement logical control points for the individual herd. Many control strategies may be effective for more than one disease. A comprehensive look at the operation is necessary to make sure that the cost of the biosecurity plan does not exceed the return in prevented disease and increased production over the planning period.
Abortion, Veterinary↗
When do tissues and cells become products? Regulatory oversight of emerging biological therapies.
Although therapeutics derived from biological sources have been subjected to regulatory oversight for some time, the products used in transplantation procedures have historically been exempt from this oversight. These products have been viewed as being part of medical practice rather than as the result of mainstream pharmaceutical manufacture. Furthermore, their unique source makes them difficult to assess in traditional regulatory systems based on the tenets of pharmaceutical quality control. With the increasing use of transplantation therapies to both replace dysfunctional organs and to influence genetic and metabolic processes, public health concerns on these therapies have increased. In addition, it is recognized that therapeutic claims for some of these interventions need to be properly assessed. These considerations have led the established regulatory agencies of the developed world to develop new regulatory paradigms for the products of transplantation practice. While a number of concerns have driven these developments, the minimization of infectious disease risk remains the paramount driver for introducing these regulatory systems. More than the regulation of medicines and medical devices manufactured in traditional pharmaceutical modes, the regulation of cell and tissue products is intimately linked to areas of public health policy and funding. This places regulators in a challenging position as they attempt to reconcile their roles as independent assessors with the needs of the overall public health framework. This is particularly difficult when considering measures which may affect access to life saving therapies. Regulators have recognized the need to assess these therapies through systems which incorporate consideration of risk-benefit ratios and include mechanisms for transparent and accountable release of products when full compliance to traditional concepts of manufacturing practice is not possible.
Biological Therapy↗
[Epidemiological aspects of nonspecific prevention of infectious diseases].
Whether immunomodulators may be used not only to treat immunodeficiencies, but to prevent infectious diseases has been under general discussion in the past years. The use of immunomodulators is mostly substantiated and promising in preventing polyetiological infections (e.g. acute respiratory diseases) against which there are not available specific preventing agents (vaccines) or the latter, if available, are ineffective. This has been evidenced by controlled epidemiological tests that show the potential and actual efficiency of immunomodulators as agents of nonspecific prevention of infectious diseases. The basic lines of studies, which make it possible to elaborate the tactics of drug use, based on the definition of epidemic indications and on the choice of the optimal preventive measures, are substantiated.
Adjuvants, Immunologic↗
[Results of the work of sanitary-epidemiologic service in Poland during last 85 years and perspectives for the future].
Just after the First World War, when Poland received independence, activity of sanitary-epidemiological service was included as the most important in the country. In this time epidemiological situation of infectious diseases was unsuccessful, especially concerning typhus exantematicus, typhoid fever, dysentery, diphtheria, tuberculosis. National Central Epidemiological Institute and since 1923 National Institute of Hygiene together with filias in some voivodships up to 1954 were appointed as sanitary epidemiological service especially to control the infectious diseases. In 1954 National Sanitary Inspection was appointed as official institution of central administration in the country to the hygienic and antiepidemiological problems and National Institute of Hygiene stated to work as scientific unit only. National Sanitary Inspection was organised as the net of sanitary-epidemiological stations in voivodeships, districts and as frontiers stations.
Communicable Disease Control↗
Infectious diseases in schools and child care facilities.
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Child↗
AIDS and the American health polity: the history and prospects of a crisis of authority.
In 1981, a profound crisis of authority was transforming the American health polity. Changing priorities between infectious and chronic diseases, communal and individual responsibilities for health, and comprehensive services and cost control created a fragmented health polity, leaderless and ill-equipped to address the AIDS epidemic. The American health polity may best serve the public interest when institutions within it do not accept fragmentation as the goal and the norm of health affairs.
Acquired Immunodeficiency Syndrome↗
Managing emerging diseases borne by fruit bats (flying foxes), with particular reference to henipaviruses and Australian bat lyssavirus.
Since 1994, a number of novel viruses have been described from bats in Australia and Malaysia, particularly from fruit bats belonging to the genus Pteropus (flying foxes), and it is probable that related viruses will be found in other countries across the geographical range of other members of the genus. These viruses include Hendra and Nipah viruses, members of a new genus, Henipaviruses, within the family Paramyxoviridae; Menangle and Tioman viruses, new members of the Rubulavirus genus within the Paramyxoviridae; and Australian bat lyssavirus (ABLV), a member of the Lyssavirus genus in the family Rhabdoviridae. All but Tioman virus are known to be associated with human and/or livestock diseases. The isolation, disease associations and biological properties of the viruses are described, and are used as the basis for developing management strategies for disease prevention or control. These strategies are directed largely at disease minimization through good farm management practices, reducing the potential for exposure to flying foxes, and better disease recognition and diagnosis, and for ABLV specifically, the use of rabies vaccine for pre- and post-exposure prophylaxis. Finally, an intriguing and long-term strategy is that of wildlife immunization through plant-derived vaccination.
Animals↗
Adaptive chronic infection, structured stress, and medical magic bullets: do reductionist cures select for holistic diseases?
With a generalized language-of-thought argument for immune cognition, we model how population-directed, structured, psychosocial stress can impose an image of itself on the coevolutionary conflict between a highly adaptive chronic infection and the immune response. As population-level structured stress appears a fundamental part of the biology of disease, we raise the possibility that simplistic individual-oriented magic-bullet drug treatments, vaccines, and risk-reduction programs that do not address the fundamental living and working conditions which underlie disease ecology will fail to control many current epidemics. In addition, such reductionist interventions may go so far as to select for more holistic pathogens characterized by processes operating at multiple levels of biocultural organization. The complications are representative of the concerns of cultural immunology, a new field of study.
Adaptation, Physiological↗
Emergency departments (EDs) in the United Kingdom (UK) are not prepared for emerging biological threats and bioterrorism.
OBJECTIVE: To assess the preparedness of emergency departments (EDs) in the United Kingdom (UK) for the management of potential biological incidents. METHODS: We telephoned all hospitals in the UK listed as having a major ED. We surveyed their ED facilities and procedures for managing patients with infectious diseases. We determined how many of the EDs had an isolation room available and, if present, whether this had an independent ventilation system and separate access from outside the ED. In addition, we determined how many of the EDs would isolate patients with suspected cases of chickenpox, tuberculosis (TB), severe acute respiratory syndrome (SARS) and other suspicious infections. RESULTS: We obtained complete data from 203 (79%) of the 257 hospitals approached. Only 49 (24%) of these hospitals had isolation facilities available in the ED. Of these 49 EDs, 30 (61%) reported an independent ventilation system and 18 (37%) reported a separate access from outside the ED. The majority of EDs would isolate patients with potential infectious diseases, however, 47 (23%) would not isolate patients with suspected chickenpox, 37 (18%) EDS would not isolate patients with suspected TB, 12 (6%) EDS would not isolate patients with suspected SARS and 55 (27%) EDS would not isolate patients with other suspicious infections. CONCLUSION: EDs in the UK are not prepared for emerging biological threats and bioterrorism. With current facilities and procedures it is highly likely that an infectious agent will spread to staff and other patients in any future biological incident.
Bioterrorism↗
History of U.S. military contributions to the understanding, prevention, and treatment of infectious diseases: an overview.
The contributions of U.S. military and affiliated civilian personnel to the advancement of mankind's understanding, prevention, and treatment of infectious diseases are innumerable. This supplement of Military Medicine has been produced by the Armed Forces Infectious Diseases Society (AFIDS) to review and highlight the accomplishments of U.S. Department of Defense military and civilian researchers in this field of study. Contributions by U.S. Armed Forces investigators to better the health of the world are documented in the 11 articles that follow.
Communicable Disease Control↗
Special challenges of maintaining wild animals in captivity in South America.
The author summarises the occurrence of major diseases in wild animals maintained in captivity in South America. The epidemiology, impact and significance of the diseases are discussed, together with appropriate husbandry practices to control and prevent transmissible diseases. The following animal groups and pathologies are considered in this review: poxvirus dermatitis, gastroenteritis, pneumonia, amoebosis and coccidiosis in reptiles, management practices and diseases (including botulism, bacterial enteritis, psittacosis, aspergillosis and parasitic diseases in birds), enterocolitis, pneumonias and internal parasites in non-human primates, canine distemper, parvoviruses, babesiosis, internal and external parasites in carnivores, tuberculosis and enteritis in tapirs, haemorrhagic disease in cervids.
Animal Husbandry↗
[The beginning of health education in Quebec: 1880-1901].
Bacteriological discoveries of the last third of the nineteenth century gave rise to radical shifts in understanding the causes and methods of controlling infectious diseases. In Quebec, between 1880-1900, two physicians and a women's organization led the health education movement. We describe firstly the origins of that movement within the context of public health conditions. Secondly we analyze the content of an educational popular periodical: Le Journal d'hygiène populaire, which the two physicians edited in succession. Lastly, we discuss the establishment and contributions of the Montreal Local Council of Women (MLCW).
Communicable Disease Control↗
Veterinary medicine protecting and promoting the public's health and well-being.
Dr. Calvin Schwabe's vision of "One Medicine" has long inspired many in the public health community to strive toward bringing human and veterinary medicine together to improve the public's health and well-being around the world. In an increasingly human-dominated world, as Dr. Schwabe suggested many years ago, human health provides the most-logical unifying or apical cause in veterinary medicine's hierarchy of values. Veterinarians in all aspects of the profession-have opportunity and responsibility to protect the health and well-being of people in all that they do, including protecting food security and safety; addressing threats to antibiotic sensitivity; preventing and controlling zoonotic emerging infectious diseases; protecting environments and ecosystems; participating in bio- and agro-terrorism preparedness and response; using their skills to confront non-zoonotic diseases (such as malaria, HIV/AIDS, vaccine preventable diseases, chronic diseases and injuries); strengthening the public-health infrastructure; and advancing medical science through research. This article provides an overview of contributions made by veterinarians in each of these areas, and discusses the challenges to be overcome and the need for strategic thinking and action to achieve the vision of "one medicine".
Animals↗